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Mechanism of the anti-angiogenic effect of Avemar on tumor cells.
Imir NG, Aydemir E, Şimşek E. Imir NG, et al. Oncol Lett. 2018 Feb;15(2):2673-2678. doi: 10.3892/ol.2017.7604. Epub 2017 Dec 13. Oncol Lett. 2018. PMID: 29434991 Free PMC article.
Avemar has numerous biological activities, and several recent studies have reported that it may also have metastatic and anti-angiogenic effects. ...VEGF and Cox-2 protein and mRNA levels were significantly lower in Avemar-treated cells than in untreated cells. The
Avemar has numerous biological activities, and several recent studies have reported that it may also have metastatic and anti-angioge
Fermented wheat germ extract (Avemar) in the treatment of cancer and autoimmune diseases.
Boros LG, Nichelatti M, Shoenfeld Y. Boros LG, et al. Ann N Y Acad Sci. 2005 Jun;1051:529-42. doi: 10.1196/annals.1361.097. Ann N Y Acad Sci. 2005. PMID: 16126993 Review.
Avemar, the product of industrial fermentation of wheat germ, possesses unique cancer-fighting characteristics. Taken orally, Avemar can inhibit metastatic tumor dissemination and proliferation during and after chemotherapy, surgery, or radiation. ...
Avemar, the product of industrial fermentation of wheat germ, possesses unique cancer-fighting characteristics. Taken orally, Avem
Inhibitory Effects of AVEMAR on Proliferation and Metastasis of Oral Cancer Cells.
Yang MD, Chang WS, Tsai CW, Wang MF, Chan YC, Chan KC, Lu MC, Kao AW, Hsu CM, Bau DT. Yang MD, et al. Nutr Cancer. 2016;68(3):473-80. doi: 10.1080/01635581.2016.1153668. Epub 2016 Mar 23. Nutr Cancer. 2016. PMID: 27007465
In this study, the potential of AVEMAR to inhibit tumor proliferation and metastasis of oral cancer was first investigated. Antiproliferative activity of AVEMAR was determined in human oral squamous carcinoma SCC-4 cells by MTT methodology. ...
In this study, the potential of AVEMAR to inhibit tumor proliferation and metastasis of oral cancer was first investigated. Antiproli …
Avemar and Echinacea extracts enhance mobilization and homing of CD34(+) stem cells in rats with acute myocardial infarction.
Abdelmonem M, Kassem SH, Gabr H, Shaheen AA, Aboushousha T. Abdelmonem M, et al. Stem Cell Res Ther. 2015 Sep 14;6(1):172. doi: 10.1186/s13287-015-0171-5. Stem Cell Res Ther. 2015. PMID: 26369808 Free PMC article.
AMI rats were either post-treated or pre- and post-treated daily with oral doses of Avemar (121 mg/kg) or Echinacea (130 mg/kg). In whole blood, the number of CD34(+) cells was measured by flow cytometry and their homing to the myocardium was immunohistochemically assessed …
AMI rats were either post-treated or pre- and post-treated daily with oral doses of Avemar (121 mg/kg) or Echinacea (130 mg/kg). In w …
Avemar (wheat germ extract) in cancer prevention and treatment.
Telekes A, Hegedus M, Chae CH, Vékey K. Telekes A, et al. Nutr Cancer. 2009;61(6):891-9. doi: 10.1080/01635580903285114. Nutr Cancer. 2009. PMID: 20155632
All of these lead to apoptosis of tumor cells. The wide range of biological activity of Avemar probably cannot be explained by only one active ingredient. Since there are numerous experimental data and the clinical benefit repeatedly confirmed Avemar can be one of t …
All of these lead to apoptosis of tumor cells. The wide range of biological activity of Avemar probably cannot be explained by only o …
Synergistic effect of Avemar on proinflammatory cytokine production and Ras-mediated cell activation.
Telekes A, Kiss-Tóth E, Nagy T, Qwarnstrom EE, Kúsz E, Polgár T, Resetár A, Dower SK, Duda E. Telekes A, et al. Ann N Y Acad Sci. 2005 Jun;1051:515-28. doi: 10.1196/annals.1361.096. Ann N Y Acad Sci. 2005. PMID: 16126992
Macrophages activated by lipopolysaccharide and/or phorbol esters exhibited high sensitivity to Avemar, a fermented wheat germ extract. Avemar synergized with lipopolysaccharide and PMA in the induction of the transcription of cytokine genes and release of inflammat …
Macrophages activated by lipopolysaccharide and/or phorbol esters exhibited high sensitivity to Avemar, a fermented wheat germ extrac …
Avemar, a nontoxic fermented wheat germ extract, induces apoptosis and inhibits ribonucleotide reductase in human HL-60 promyelocytic leukemia cells.
Saiko P, Ozsvar-Kozma M, Madlener S, Bernhaus A, Lackner A, Grusch M, Horvath Z, Krupitza G, Jaeger W, Ammer K, Fritzer-Szekeres M, Szekeres T. Saiko P, et al. Cancer Lett. 2007 Jun 8;250(2):323-8. doi: 10.1016/j.canlet.2006.10.018. Epub 2006 Nov 29. Cancer Lett. 2007. PMID: 17137710
Avemar (MSC) is a nontoxic fermented wheat germ extract demonstrated to significantly improve the survival rate in patients suffering from various malignancies. ...We conclude that Avemar exerts a number of beneficial effects which could support conventional chemoth
Avemar (MSC) is a nontoxic fermented wheat germ extract demonstrated to significantly improve the survival rate in patients suffering
AVEMAR (a new benzoquinone-containing natural product) administration interferes with the Th2 response in experimental SLE and promotes amelioration of the disease.
Ehrenfeld M, Blank M, Shoenfeld Y, Hidvegi M. Ehrenfeld M, et al. Lupus. 2001;10(9):622-7. doi: 10.1191/096120301682430203. Lupus. 2001. PMID: 11678450
The potential of oral treatment with AVEMAR (AVEMAR), a new benzoquinone-containing fermentation product of wheat germ, on features of experimental systemic lupus erythematosus (SLE) in naive mice, induced by idiotypic manipulation, was studied. We assessed the effe …
The potential of oral treatment with AVEMAR (AVEMAR), a new benzoquinone-containing fermentation product of wheat germ, on fea …
Avemar, a nontoxic fermented wheat germ extract, attenuates the growth of sensitive and 5-FdUrd/Ara-C cross-resistant H9 human lymphoma cells through induction of apoptosis.
Saiko P, Ozsvar-Kozma M, Graser G, Lackner A, Grusch M, Madlener S, Krupitza G, Jaeger W, Hidvegi M, Agarwal RP, Fritzer-Szekeres M, Szekeres T. Saiko P, et al. Oncol Rep. 2009 Mar;21(3):787-91. Oncol Rep. 2009. PMID: 19212640
Avemar (MSC) is a nontoxic fermented wheat germ extract, which has been shown to significantly improve the survival rate in patients suffering from various malignancies. ...As MSC treatment likely overcomes 5-FdUrd/Ara-C resistance, further investigations to elucidate the
Avemar (MSC) is a nontoxic fermented wheat germ extract, which has been shown to significantly improve the survival rate in patients
Immunologic and biochemical effects of the fermented wheat germ extract Avemar.
Illmer C, Madlener S, Horvath Z, Saiko P, Losert A, Herbacek I, Grusch M, Krupitza G, Fritzer-Szekeres M, Szekeres T. Illmer C, et al. Exp Biol Med (Maywood). 2005 Feb;230(2):144-9. doi: 10.1177/153537020523000209. Exp Biol Med (Maywood). 2005. PMID: 15673563
Avemar (MSC) is a nontoxic fermented wheat germ extract demonstrated to have antitumor effects. ...In addition, we determined the effects of Avemar on the activity of cyclooxygenase-1 and -2. Both enzymes were significantly inhibited by Avemar with IC50 value
Avemar (MSC) is a nontoxic fermented wheat germ extract demonstrated to have antitumor effects. ...In addition, we determined the eff
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