Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2009 3
2010 2
2012 1
2013 1
2015 1
2016 1
2017 2
2020 1
2024 1
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

11 results

Results by year

Filters applied: . Clear all
Page 1
Functional characterization of variants in human ABCC11, an axillary osmidrosis risk factor.
Toyoda Y, Matsuo H, Takada T. Toyoda Y, et al. Hum Cell. 2024 Jul;37(4):1070-1079. doi: 10.1007/s13577-024-01074-x. Epub 2024 May 15. Hum Cell. 2024. PMID: 38750405
Accumulating evidence indicates that ABCC11 wild type is responsible for the high-secretion phenotypes in human apocrine glands including wet type of earwax and the risk of axillary osmidrosis. ...Therefore, in addition to p.G180R (a well-charac …
Accumulating evidence indicates that ABCC11 wild type is responsible for the high-secretion phenotypes in human apocrine gl …
Correlation of axillary osmidrosis to a SNP in the ABCC11 gene determined by the Smart Amplification Process (SmartAmp) method.
Inoue Y, Mori T, Toyoda Y, Sakurai A, Ishikawa T, Mitani Y, Hayashizaki Y, Yoshimura Y, Kurahashi H, Sakai Y. Inoue Y, et al. J Plast Reconstr Aesthet Surg. 2010 Aug;63(8):1369-74. doi: 10.1016/j.bjps.2009.06.029. Epub 2009 Jul 21. J Plast Reconstr Aesthet Surg. 2010. PMID: 19625231
Axillary osmidrosis (AO) is caused by apocrine glands secretions that are converted to odouriferous compounds by bacteria. ...Recently, a non-synonymous single nucleotide polymorphism (SNP) 538G> A (Gly180Arg) in the human adenosine triphosphate (AT …
Axillary osmidrosis (AO) is caused by apocrine glands secretions that are converted to odouriferous compounds by …
Association between the ABCC11 gene polymorphism and the expression of apolipoprotein D by the apocrine glands in axillary osmidrosis.
Zhu Z, Zhang H, Luo G, Xu N, Pan Z. Zhu Z, et al. Mol Med Rep. 2015 Jun;11(6):4463-7. doi: 10.3892/mmr.2015.3274. Epub 2015 Jan 29. Mol Med Rep. 2015. PMID: 25633187
The present study aimed to investigate the association between a 538 G>A single-nucleotide polymorphism (SNP) of the ABCC11 gene and the mRNA expression levels of ApoD in the apocrine gland of patients with osmidrosis. ...In conclusion, the results …
The present study aimed to investigate the association between a 538 G>A single-nucleotide polymorphism (SNP) of the ABCC11 gene a …
Clinical and Molecular Evidence of ABCC11 Protein Expression in Axillary Apocrine Glands of Patients with Axillary Osmidrosis.
Toyoda Y, Takada T, Gomi T, Nakagawa H, Ishikawa T, Suzuki H. Toyoda Y, et al. Int J Mol Sci. 2017 Feb 15;18(2):417. doi: 10.3390/ijms18020417. Int J Mol Sci. 2017. PMID: 28212277 Free PMC article.
However, little data are available for the expression of ABCC11 protein in human axillary apocrine glands that produce apocrine sweat-a source of odor from the armpits. ...Furthermore, we examined the expression of ABCC11 protein in human …
However, little data are available for the expression of ABCC11 protein in human axillary apocrine glands that p …
Regulation of the Axillary Osmidrosis-Associated ABCC11 Protein Stability by N-Linked Glycosylation: Effect of Glucose Condition.
Toyoda Y, Takada T, Miyata H, Ishikawa T, Suzuki H. Toyoda Y, et al. PLoS One. 2016 Jun 9;11(6):e0157172. doi: 10.1371/journal.pone.0157172. eCollection 2016. PLoS One. 2016. PMID: 27281343 Free PMC article.
ABCC11 wild-type is responsible for the high-secretion phenotypes in human apocrine glands, such as that of wet-type ear wax, and the risk of axillary osmidrosis. ...These results suggest that N-linked glycosylation is important for the protein …
ABCC11 wild-type is responsible for the high-secretion phenotypes in human apocrine glands, such as that of wet-type ea …
Soy Isoflavone Genistein Inhibits an Axillary Osmidrosis Risk Factor ABCC11: In Vitro Screening and Fractional Approach for ABCC11-Inhibitory Activities in Plant Extracts and Dietary Flavonoids.
Saito H, Toyoda Y, Hirata H, Ota-Kontani A, Tsuchiya Y, Takada T, Suzuki H. Saito H, et al. Nutrients. 2020 Aug 14;12(8):2452. doi: 10.3390/nu12082452. Nutrients. 2020. PMID: 32824087 Free PMC article.
Axillary osmidrosis (AO) is a common chronic skin condition characterized by unpleasant body odors emanating from the armpits, and its aetiology is not fully understood. ...Recent studies have revealed that human ATP-binding cassette transporter C11 (ABCC11) …
Axillary osmidrosis (AO) is a common chronic skin condition characterized by unpleasant body odors emanating from the armpits, …
A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene.
Nakano M, Miwa N, Hirano A, Yoshiura K, Niikawa N. Nakano M, et al. BMC Genet. 2009 Aug 4;10:42. doi: 10.1186/1471-2156-10-42. BMC Genet. 2009. PMID: 19650936 Free PMC article.
AO was defined here as a clinical condition of individuals with a deep anxiety regarding axillary odor and had undergone the removal of bilateral axillary apocrine glands. RESULTS: A comparison of the frequencies of genotypes at rs17822931 in the 79 AO …
AO was defined here as a clinical condition of individuals with a deep anxiety regarding axillary odor and had undergone the removal …
Pharmacogenetics of human ABC transporter ABCC11: new insights into apocrine gland growth and metabolite secretion.
Ishikawa T, Toyoda Y, Yoshiura K, Niikawa N. Ishikawa T, et al. Front Genet. 2013 Jan 2;3:306. doi: 10.3389/fgene.2012.00306. eCollection 2012. Front Genet. 2013. PMID: 23316210 Free PMC article.
The recent finding that the non-synonymous single nucleotide polymorphisms (SNP) 538G > A (rs17822931; Gly180Arg) in the ABCC11 gene determines the type of earwax in humans has shed light on the novel function of this ABC (ATP-binding cassette) transporter in apocrin …
The recent finding that the non-synonymous single nucleotide polymorphisms (SNP) 538G > A (rs17822931; Gly180Arg) in the ABCC11 ge …
Pharmacogenomics of human ABC transporter ABCC11 (MRP8): potential risk of breast cancer and chemotherapy failure.
Toyoda Y, Ishikawa T. Toyoda Y, et al. Anticancer Agents Med Chem. 2010 Oct 1;10(8):617-24. doi: 10.2174/187152010794473975. Anticancer Agents Med Chem. 2010. PMID: 21182469 Free PMC article. Review.
The SNP variant lacking N-linked glycosylation is recognized as a misfolded protein in the endoplasmic reticulum (ER) and readily undergoes proteasomal degradation. This ER-associated degradation of ABCC11 protein underlies the molecular mechanism of affecting the function …
The SNP variant lacking N-linked glycosylation is recognized as a misfolded protein in the endoplasmic reticulum (ER) and readily undergoes …
A missense variant of the ABCC11 gene is associated with Axillary Osmidrosis susceptibility and clinical phenotypes in the Chinese Han Population.
Ren Y, Liu W, Chen J, Wang J, Wang K, Zhou J, Cai S, Zheng M, Liu J, Liu L, Xue D. Ren Y, et al. Sci Rep. 2017 May 9;7:46335. doi: 10.1038/srep46335. Sci Rep. 2017. PMID: 28485377 Free PMC article.
Axillary osmidrosis (AO) is a common condition characterized by an offensive odor arising from apocrine gland secretions in the axillae that socially and psychologically impairs affected individuals. ...Our study concluded that the association of rs178 …
Axillary osmidrosis (AO) is a common condition characterized by an offensive odor arising from apocrine gland se …
11 results