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28 results

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Page 1
Drug-drug interactions involving classic psychedelics: A systematic review.
Halman A, Kong G, Sarris J, Perkins D. Halman A, et al. J Psychopharmacol. 2024 Jan;38(1):3-18. doi: 10.1177/02698811231211219. Epub 2023 Nov 20. J Psychopharmacol. 2024. PMID: 37982394 Free PMC article.
However, our understanding of the potential interactions and outcomes when using these substances in combination with other drugs is limited. This systematic review aims to provide a comprehensive overview of the current research on drug-drug interactions …
However, our understanding of the potential interactions and outcomes when using these substances in combination with other drugs is …
Predicting drug-drug interactions between ayahuasca alkaloids and SSRIs using physiologically based pharmacokinetic modeling.
Ribeiro GSG, Paranhos BAPB, Dörr F, Yonamine M, Villanova B, Guerra LTL, Raminelli AO, Reis JAS, de Paula CC, Zacharias ABV, Cecílio Hallak JE, Dos Santos RG, Martins FS, Marcourakis T. Ribeiro GSG, et al. Front Mol Biosci. 2026 Feb 18;13:1768402. doi: 10.3389/fmolb.2026.1768402. eCollection 2026. Front Mol Biosci. 2026. PMID: 41788629 Free PMC article.
Drug-drug interaction simulations were performed under acute and chronic SSRI dosing conditions. ...This study provides a mechanistic and quantitative framework for assessing interaction risks between ayahuasca alkaloids and SSRIs, supporting clinical decisio …
Drug-drug interaction simulations were performed under acute and chronic SSRI dosing conditions. ...This study provides a mech …
The pharmacological interaction of compounds in ayahuasca: a systematic review.
Ruffell S, Netzband N, Bird C, Young AH, Juruena MF. Ruffell S, et al. Braz J Psychiatry. 2020 Nov-Dec;42(6):646-656. doi: 10.1590/1516-4446-2020-0884. Braz J Psychiatry. 2020. PMID: 32638916 Free PMC article.
Ayahuasca is a South American psychoactive plant brew used as traditional medicine in spiritual and in cultural rituals. ...At present, it is unclear whether the pharmacological interactions in ayahuasca act synergistically or additively to produce psychoacti …
Ayahuasca is a South American psychoactive plant brew used as traditional medicine in spiritual and in cultural rituals. ...At presen …
Ayahuasca: What Healthcare Providers Need to Know.
Goldin D, Salani D. Goldin D, et al. J Addict Nurs. 2021 Apr-Jun 01;32(2):167-173. doi: 10.1097/JAN.0000000000000405. J Addict Nurs. 2021. PMID: 34060770
The consequences of ayahuasca use remain uncertain because of poor quality control, unpredictability, and polydrug interactions. Nurses, advanced practice nurses, and other healthcare providers working in outpatient settings, hospitals, and treatment centers need to …
The consequences of ayahuasca use remain uncertain because of poor quality control, unpredictability, and polydrug interactions …
Shared functional connectome fingerprints following ritualistic ayahuasca intake.
Mallaroni P, Mason NL, Kloft L, Reckweg JT, van Oorsouw K, Toennes SW, Tolle HM, Amico E, Ramaekers JG. Mallaroni P, et al. Neuroimage. 2024 Jan;285:120480. doi: 10.1016/j.neuroimage.2023.120480. Epub 2023 Dec 6. Neuroimage. 2024. PMID: 38061689 Free article.
However, whether such "fingerprints" persist under altered states of consciousness is unknown. Ayahuasca is a potent serotonergic psychedelic which produces a widespread dysregulation of functional connectivity. Used communally in religious ceremonies, its shared use may h …
However, whether such "fingerprints" persist under altered states of consciousness is unknown. Ayahuasca is a potent serotonergic psy …
Screening the receptorome for plant-based psychoactive compounds.
O'Connor KA, Roth BL. O'Connor KA, et al. Life Sci. 2005 Dec 22;78(5):506-11. doi: 10.1016/j.lfs.2005.09.002. Epub 2005 Oct 6. Life Sci. 2005. PMID: 16213532 Review.
The "receptorome" (that portion of the genome encoding ligand reception) encompasses more than 8% of the human genome (Roth et al., 2004) and as such provides a large number of possible targets for psychoactive drug interactions. A systematic, comprehensive study is …
The "receptorome" (that portion of the genome encoding ligand reception) encompasses more than 8% of the human genome (Roth et al., 2004) an …
Novel harmala-ocudelic tuning (HOT) for ocular disorders.
Lansky ES. Lansky ES. Med Hypotheses. 2020 Oct;143:109834. doi: 10.1016/j.mehy.2020.109834. Epub 2020 May 16. Med Hypotheses. 2020. PMID: 32498006
One drug potentially satisfying these criteria is the common, botanically-occurring indole alkaloid and "major hallucinogen," harmine. ...Though the possibility of drug-drug or herb-drug interactions exists, especially with SSRIs, at correct pat …
One drug potentially satisfying these criteria is the common, botanically-occurring indole alkaloid and "major hallucinogen," harmine …
Brain-body integromics of the ayahuasca experience.
Madrid-Gambin F, Mallaroni P, Haro N, Pozo OJ, Mason NL, Reckweg JT, Kloft-Heller L, van Oorsouw K, Toennes SW, Ramaekers JG. Madrid-Gambin F, et al. Biomed Pharmacother. 2026 Jun;199:119391. doi: 10.1016/j.biopha.2026.119391. Epub 2026 Apr 23. Biomed Pharmacother. 2026. PMID: 42030660 Free article.
Ayahuasca is a psychoactive brew containing N,N-dimethyltryptamine (DMT) and beta-carboline alkaloids that induces marked alterations in perception, emotion and self-referential processing. ...Together, these findings indicate that psychedelic states reflect coordinated, s …
Ayahuasca is a psychoactive brew containing N,N-dimethyltryptamine (DMT) and beta-carboline alkaloids that induces marked alterations …
Ayahuasca preparations and serotonin reuptake inhibitors: a potential combination for severe adverse interactions.
Callaway JC, Grob CS. Callaway JC, et al. J Psychoactive Drugs. 1998 Oct-Dec;30(4):367-9. doi: 10.1080/02791072.1998.10399712. J Psychoactive Drugs. 1998. PMID: 9924842
The Amazonian psychoactive plant beverage ayahuasca has attracted increasing interest in recent years. Little attention has been given, however, to potentially dangerous interactions with other drugs. ...Caution is advised when combining ayahuasca with certai …
The Amazonian psychoactive plant beverage ayahuasca has attracted increasing interest in recent years. Little attention has been give …
Ayahuasca: An ancient sacrament for treatment of contemporary psychiatric illness?
Malcolm BJ, Lee KC. Malcolm BJ, et al. Ment Health Clin. 2018 Mar 23;7(1):39-45. doi: 10.9740/mhc.2017.01.039. eCollection 2017 Jan. Ment Health Clin. 2018. PMID: 29955496 Free PMC article.
Due to its MAOI properties, there are serious drug interactions that may be of concern among patients who participate in ayahuasca use. The objectives of this paper are to describe ayahuasca's pharmacology, potential drug interactions …
Due to its MAOI properties, there are serious drug interactions that may be of concern among patients who participate in ay …
28 results