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In silico exploration of phytocompounds from AYUSH-64 medicinal plants against SARS CoV-2 RNA-dependent RNA polymerase.
Cheemanapalli S, Golla R, Pagidi S, Pantangi S. Cheemanapalli S, et al. J Ayurveda Integr Med. 2024 Nov-Dec;15(6):101026. doi: 10.1016/j.jaim.2024.101026. Epub 2024 Nov 1. J Ayurveda Integr Med. 2024. PMID: 39488119 Free PMC article.
BACKGROUND: The AYUSH 64 formulation helps to treat mild to moderate cases of COVID-19. Although several drugs have been proposed to combat COVID-19, no medication is available for SARS-CoV-2 infection. ...RESULTS: Among the tested, five phytocompounds (Picroside I, …
BACKGROUND: The AYUSH 64 formulation helps to treat mild to moderate cases of COVID-19. Although several drugs have been propo …
Evaluating therapeutic potential of AYUSH-64 constituents against omicron variant of SARS-CoV-2 using ensemble docking and simulations.
Jani V, Koulgi S, Uppuladinne MVN, Thrigulla SR, Gundeti M, Prasad GP, Kumar S, Narayanam S, Sonavane U, Joshi R. Jani V, et al. Curr Res Struct Biol. 2024 May 31;7:100151. doi: 10.1016/j.crstbi.2024.100151. eCollection 2024. Curr Res Struct Biol. 2024. PMID: 38881558 Free PMC article.
One of the earlier, in-silico study has shown the binding of the constituents of AYUSH-64 to the main protease (M(pro)) of the SARS-CoV-2. This study enlisted four phytochemicals of AYUSH-64, which were found to have significant binding with the M(pro) …
One of the earlier, in-silico study has shown the binding of the constituents of AYUSH-64 to the main protease (M(pro)) of the …
Effect of herbal extracts and Saroglitazar on high-fat diet-induced obesity, insulin resistance, dyslipidemia, and hepatic lipidome in C57BL/6J mice.
Kumari D, Gautam J, Sharma V, Gupta SK, Sarkar S, Jana P, Singhal V, Babele P, Kamboj P, Bajpai S, Tandon R, Kumar Y, Dikshit M. Kumari D, et al. Heliyon. 2023 Nov 4;9(11):e22051. doi: 10.1016/j.heliyon.2023.e22051. eCollection 2023 Nov. Heliyon. 2023. PMID: 38027691 Free PMC article.
We evaluated the effects of select herbal extracts (Tinospora cordifolia [TC], Tinospora cordifolia with Piper longum [TC + PL], Withania somnifera [WS], Glycyrrhiza glabra [GG], AYUSH-64 [AY-64], and Saroglitazar [S]) on various parameters in a diet-induced obesity …
We evaluated the effects of select herbal extracts (Tinospora cordifolia [TC], Tinospora cordifolia with Piper longum [TC + PL], Withania so …
Evaluation of Ayush-64 (a Polyherbal Formulation) and Its Ingredients in the Syrian Hamster Model for SARS-CoV-2 Infection Reveals the Preventative Potential of Alstonia scholaris.
Rizvi ZA, Madan U, Tripathy MR, Goswami S, Mani S, Awasthi A, Dikshit M. Rizvi ZA, et al. Pharmaceuticals (Basel). 2023 Sep 21;16(9):1333. doi: 10.3390/ph16091333. Pharmaceuticals (Basel). 2023. PMID: 37765142 Free PMC article.
In the current study, we evaluated the efficacy of Ayush-64 (A64), a polyherbal formulation containing Alstonia scholaris (L.) R. Br. (A. scholaris), Caesalpinia crista L. ...
In the current study, we evaluated the efficacy of Ayush-64 (A64), a polyherbal formulation containing Alstonia scholaris (L.) …
Co-administration of AYUSH 64 as an adjunct to standard of care in mild and moderate COVID-19: A randomized, controlled, multicentric clinical trial.
Chopra A, Tillu G, Chuadhary K, Reddy G, Srivastava A, Lakdawala M, Gode D, Reddy H, Tamboli S, Saluja M, Sarmukaddam S, Gundeti M, Raut AK, Rao BCS, Yadav B, Srikanth N, Patwardhan B. Chopra A, et al. PLoS One. 2023 Mar 16;18(3):e0282688. doi: 10.1371/journal.pone.0282688. eCollection 2023. PLoS One. 2023. PMID: 36928877 Free PMC article. Clinical Trial.
OBJECTIVE: Evaluate the efficacy of AYUSH 64, a standard polyherbal Ayurvedic drug in COVID-19. METHODS: During the first pandemic wave, 140 consenting and eligible hospitalized adult participants with mild-moderate symptomatic disease (specific standard RT-PCR assa …
OBJECTIVE: Evaluate the efficacy of AYUSH 64, a standard polyherbal Ayurvedic drug in COVID-19. METHODS: During the first pand …
AYUSH (Indian System of Medicines) Therapeutics for COVID-19: A Living Systematic Review and Meta-Analysis (First Update).
Thakar A, Panara K, Goyal M, Kumari R, Sungchol K. Thakar A, et al. J Integr Complement Med. 2023 Mar;29(3):139-155. doi: 10.1089/jicm.2022.0559. Epub 2022 Nov 2. J Integr Complement Med. 2023. PMID: 36322891 Review.
Results: Of 3609 studies retrieved, 17 were included in the systematic review, and 3 AYUSH therapeutics were meta-analyzed. Meta-analysis suggested that add-on AYUSH-64 likely provides therapeutic benefits by reducing time to symptom resolution (mean difference [MD] …
Results: Of 3609 studies retrieved, 17 were included in the systematic review, and 3 AYUSH therapeutics were meta-analyzed. Meta-analysis su …
In vitro effect of Withania somnifera, AYUSH-64, and remdesivir on the activity of CYP-450 enzymes: Implications for possible herb-drug interactions in the management of COVID-19.
Kasarla SS, Borse SP, Kumar Y, Sharma N, Dikshit M. Kasarla SS, et al. Front Pharmacol. 2022 Oct 12;13:973768. doi: 10.3389/fphar.2022.973768. eCollection 2022. Front Pharmacol. 2022. PMID: 36313313 Free PMC article.
Ayurvedic medicines Withania somnifera Dunal (ashwagandha) and AYUSH-64 have been used for the prevention and management of COVID-19 in India. The present study explores the effect of Ashwagandha and AYUSH-64 on important human CYP enzymes (CYP3A4, CYP …
Ayurvedic medicines Withania somnifera Dunal (ashwagandha) and AYUSH-64 have been used for the prevention and management of CO …
A methodological analysis of CTRI registered clinical trials on ayurveda interventions for COVID-19 management.
Chaudhari SS, Somvanshi PR. Chaudhari SS, et al. J Ayurveda Integr Med. 2023 Jan-Feb;14(1):100631. doi: 10.1016/j.jaim.2022.100631. Epub 2022 Aug 11. J Ayurveda Integr Med. 2023. PMID: 35971456 Free PMC article.
Most common intervention used were guduchi, ashwagandha, yashtimadhu, AYUSH-64, curcumin and chyavanprash. CONCLUSION: Although there was a surge of clinical trials on CTRI regarding ayurveda for COVID -19, the methodological quality is not up to the mark with large …
Most common intervention used were guduchi, ashwagandha, yashtimadhu, AYUSH-64, curcumin and chyavanprash. CONCLUSION: Althoug …
Disease Characteristics, Care-Seeking Behavior, and Outcomes Associated With the Use of AYUSH-64 in COVID-19 Patients in Home Isolation in India: A Community-Based Cross-Sectional Analysis.
Srikanth N, Kumar A, Chandrasekhararao B, Singhal R, Yadav B, Khanduri S, Jameela S, Rai AK, Tripathi A, Rana R, Ahmad A, Sharma BS, Jaiswal A, Kotecha R; State Level Collaborators. Srikanth N, et al. Front Public Health. 2022 Jul 6;10:904279. doi: 10.3389/fpubh.2022.904279. eCollection 2022. Front Public Health. 2022. PMID: 35900336 Free PMC article.
BACKGROUND: During the second wave of the COVID-19 pandemic in India, the Ministry of Ayush conducted a community study to provide therapeutic care to patients with asymptomatic, mild, and moderate COVID-19 in home isolation based on the empirical evidence generated on the effica …
BACKGROUND: During the second wave of the COVID-19 pandemic in India, the Ministry of Ayush conducted a community study to provide therapeut …
25 results