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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 7
1970 4
1971 3
1972 6
1973 6
1974 5
1975 7
1976 8
1977 3
1978 5
1979 7
1980 8
1981 2
1982 10
1983 13
1984 8
1985 25
1986 15
1987 27
1988 30
1989 19
1990 25
1991 34
1992 36
1993 45
1994 38
1995 41
1996 34
1997 34
1998 48
1999 28
2000 35
2001 43
2002 32
2003 38
2004 31
2005 40
2006 39
2007 32
2008 31
2009 24
2010 33
2011 29
2012 28
2013 48
2014 37
2015 48
2016 37
2017 42
2018 28
2019 35
2020 34
2021 33
2022 29
2023 32
2024 32
2025 32
2026 10

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1,408 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Azathioprine for people with multiple sclerosis.
Ridley B, Nonino F, Baldin E, Casetta I, Iuliano G, Filippini G. Ridley B, et al. Cochrane Database Syst Rev. 2024 Dec 9;12(12):CD015005. doi: 10.1002/14651858.CD015005.pub2. Cochrane Database Syst Rev. 2024. PMID: 39651635 Free PMC article.
Given this, a review of azathioprine's benefits and harms would be timely and valuable to inform shared healthcare decisions. ...We found no evidence comparing azathioprine to other DMTs for QoL impairment (mental score), long-term adverse events (neoplasms) or mort …
Given this, a review of azathioprine's benefits and harms would be timely and valuable to inform shared healthcare decisions. ...We f …
Infliximab, azathioprine, or combination therapy for Crohn's disease.
Colombel JF, Sandborn WJ, Reinisch W, Mantzaris GJ, Kornbluth A, Rachmilewitz D, Lichtiger S, D'Haens G, Diamond RH, Broussard DL, Tang KL, van der Woude CJ, Rutgeerts P; SONIC Study Group. Colombel JF, et al. N Engl J Med. 2010 Apr 15;362(15):1383-95. doi: 10.1056/NEJMoa0904492. N Engl J Med. 2010. PMID: 20393175 Free article. Clinical Trial.
BACKGROUND: The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease are unknown. METHODS: In this randomized, double-blind trial, we evaluated the efficacy of infliximab monotherapy, azathioprine monothe …
BACKGROUND: The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease ar …
Rituximab versus azathioprine for maintenance in ANCA-associated vasculitis.
Guillevin L, Pagnoux C, Karras A, Khouatra C, Aumaître O, Cohen P, Maurier F, Decaux O, Ninet J, Gobert P, Quémeneur T, Blanchard-Delaunay C, Godmer P, Puéchal X, Carron PL, Hatron PY, Limal N, Hamidou M, Ducret M, Daugas E, Papo T, Bonnotte B, Mahr A, Ravaud P, Mouthon L; French Vasculitis Study Group. Guillevin L, et al. N Engl J Med. 2014 Nov 6;371(19):1771-80. doi: 10.1056/NEJMoa1404231. N Engl J Med. 2014. PMID: 25372085 Free article. Clinical Trial.
Twenty-five patients in each group (P=0.92) had severe adverse events; there were 44 events in the azathioprine group and 45 in the rituximab group. Eight patients in the azathioprine group and 11 in the rituximab group had severe infections, and cancer developed in …
Twenty-five patients in each group (P=0.92) had severe adverse events; there were 44 events in the azathioprine group and 45 in the r …
An open-label randomised-controlled trial of azathioprine vs. mycophenolate mofetil for the induction of remission in treatment-naive autoimmune hepatitis.
Snijders RJALM, Stoelinga AEC, Gevers TJG, Pape S, Biewenga M, Tushuizen ME, Verdonk RC, de Jonge HJM, Vrolijk JM, Bakker SF, Vanwolleghem T, de Boer YS, Baven Pronk MAMC, Beuers U, van der Meer AJ, Gerven NMFV, Sijtsma MGM, van Eijck BC, van IJzendoorn MC, van Herwaarden M, van den Brand FF, Korkmaz KS, van den Berg AP, Guichelaar MMJ, Levens AD, van Hoek B, Drenth JPH; Dutch Autoimmune Hepatitis Working Group. Snijders RJALM, et al. J Hepatol. 2024 Apr;80(4):576-585. doi: 10.1016/j.jhep.2023.11.032. Epub 2023 Dec 14. J Hepatol. 2024. PMID: 38101756 Free article. Clinical Trial.
There is genuine concern about the efficacy and tolerability of the current standard combination therapy of prednisolone and azathioprine. Mycophenolate mofetil (MMF) has emerged as an alternative option. The aim of this study was to compare MMF to azathioprine as i …
There is genuine concern about the efficacy and tolerability of the current standard combination therapy of prednisolone and azathioprine …
Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis.
Hasskamp J, Meinhardt C, Patton PH, Timmer A. Hasskamp J, et al. Cochrane Database Syst Rev. 2025 Feb 27;2(2):CD000478. doi: 10.1002/14651858.CD000478.pub5. Cochrane Database Syst Rev. 2025. PMID: 40013523 Free PMC article.
SELECTION CRITERIA: Randomized controlled trials (RCTs) of at least 24 weeks' duration comparing azathioprine or 6-mercaptopurine with placebo or any other medication, or comparing different treatment modalities of azathioprine or 6-mercaptopurine, in persons of any …
SELECTION CRITERIA: Randomized controlled trials (RCTs) of at least 24 weeks' duration comparing azathioprine or 6-mercaptopurine wit …
Safety and efficacy of tocilizumab versus azathioprine in highly relapsing neuromyelitis optica spectrum disorder (TANGO): an open-label, multicentre, randomised, phase 2 trial.
Zhang C, Zhang M, Qiu W, Ma H, Zhang X, Zhu Z, Yang CS, Jia D, Zhang TX, Yuan M, Feng Y, Yang L, Lu W, Yu C, Bennett JL, Shi FD; TANGO Study Investigators. Zhang C, et al. Lancet Neurol. 2020 May;19(5):391-401. doi: 10.1016/S1474-4422(20)30070-3. Lancet Neurol. 2020. PMID: 32333897 Free PMC article. Clinical Trial.
BACKGROUND: Azathioprine is used as a first-line treatment to prevent relapses of neuromyelitis optica spectrum disorder (NMOSD). ...Treatment-associated adverse events occurred in 36 (61%) of 59 tocilizumab-treated patients and 49 (83%) of 59 azathioprine-treated p …
BACKGROUND: Azathioprine is used as a first-line treatment to prevent relapses of neuromyelitis optica spectrum disorder (NMOSD). ... …
Azathioprine for multiple sclerosis.
Casetta I, Iuliano G, Filippini G. Casetta I, et al. Cochrane Database Syst Rev. 2007 Oct 17;2007(4):CD003982. doi: 10.1002/14651858.CD003982.pub2. Cochrane Database Syst Rev. 2007. PMID: 17943809 Free PMC article.
BACKGROUND: Azathioprine is the most widely used immunosuppressive treatment in multiple sclerosis (MS). ...This systematic review aimed to determine the trade off between the benefits and risks of azathioprine in multiple sclerosis. OBJECTIVES: To compare azathi …
BACKGROUND: Azathioprine is the most widely used immunosuppressive treatment in multiple sclerosis (MS). ...This systematic review ai …
Mycophenolate mofetil plus methotrexate versus cyclophosphamide with sequential azathioprine for treatment of Takayasu arteritis.
Sun X, Li J, Duan X, Wang Y, Chen Y, Wang Y, Zhang L, Yao D, Xue J, Wu Z, Zhao Y, Luo L, Zhang H, Zhang X, Pan L, Zeng X, Li M, Merkel PA, Tian X. Sun X, et al. Ann Rheum Dis. 2025 Oct;84(10):1733-1742. doi: 10.1016/j.ard.2025.07.018. Epub 2025 Aug 22. Ann Rheum Dis. 2025. PMID: 40849269 Free article. Clinical Trial.
OBJECTIVES: Study the efficacy and safety of mycophenolate mofetil (MMF) combined with methotrexate (MTX) compared to cyclophosphamide (CYC) followed by azathioprine (AZA) to treat active Takayasu arteritis (TAK). METHODS: Adults with active TAK were randomised in a 2:1 ra …
OBJECTIVES: Study the efficacy and safety of mycophenolate mofetil (MMF) combined with methotrexate (MTX) compared to cyclophosphamide (CYC) …
Top-down infliximab plus azathioprine versus azathioprine alone in patients with acute severe ulcerative colitis responsive to intravenous steroids: a parallel, open-label randomised controlled trial, the ACTIVE trial.
Amiot A, Seksik P, Meyer A, Stefanescu C, Wils P, Altwegg R, Vuitton L, Plastaras L, Nicolau A, Pereira B, Duveau N, Laharie D, Mboup B, Boualit M, Allez M, Rajca S, Chanteloup E, Bouguen G, Bazin T, Goutorbe F, Richard N, Moussata D, Vicaut E, Peyrin-Biroulet L. Amiot A, et al. Gut. 2025 Jan 17;74(2):197-205. doi: 10.1136/gutjnl-2024-333281. Gut. 2025. PMID: 39586616 Clinical Trial.
Eligible patients were randomly assigned to receive infliximab (IFX) and azathioprine (AZA) with a 7-day steroid tapering scheme (IFX+AZA arm) or AZA and conventional standardised steroid tapering regimen (AZA arm). ...
Eligible patients were randomly assigned to receive infliximab (IFX) and azathioprine (AZA) with a 7-day steroid tapering scheme (IFX …
Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease.
Chande N, Townsend CM, Parker CE, MacDonald JK. Chande N, et al. Cochrane Database Syst Rev. 2016 Oct 26;10(10):CD000545. doi: 10.1002/14651858.CD000545.pub5. Cochrane Database Syst Rev. 2016. PMID: 27783843 Free PMC article.
The combination of azathioprine and infliximab was significantly superior to infliximab alone for induction of steroid-free clinical remission. ...There were no statistically significant differences in withdrawals due to adverse events between azathioprine or 6-merc …
The combination of azathioprine and infliximab was significantly superior to infliximab alone for induction of steroid-free clinical …
1,408 results