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Year Number of Results
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61 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
Liu H, Yu H, Xia J, Liu L, Liu GJ, Sang H, Peinemann F. Liu H, et al. Cochrane Database Syst Rev. 2020 May 1;5(5):CD011368. doi: 10.1002/14651858.CD011368.pub2. Cochrane Database Syst Rev. 2020. PMID: 32356369 Free PMC article.
The clinical benefit of the topical acne treatments azelaic acid, salicylic acid, nicotinamide, sulphur, zinc, and alpha-hydroxy acid is unclear. ...AUTHORS' CONCLUSIONS: Compared to benzoyl peroxide, azelaic acid probably leads to a worse treatment re …
The clinical benefit of the topical acne treatments azelaic acid, salicylic acid, nicotinamide, sulphur, zinc, and alpha-hydro …
755-nm picosecond laser plus topical 20% azelaic acid compared to topical 20% azelaic acid alone for the treatment of melasma: a randomized, split-face and controlled trial.
Lai D, Cheng S, Zhou S, Hao J, Chen H, Jia K, Liu H, Cui Y. Lai D, et al. Lasers Med Sci. 2024 Apr 24;39(1):113. doi: 10.1007/s10103-024-04052-9. Lasers Med Sci. 2024. PMID: 38656631 Clinical Trial.
PURPOSE: Melasma remains a refractory skin condition that needs to be actively explored. Azelaic acid has been used for decades as a topical agent to improve melasma through multiple mechanisms, however, there is a lack of research on its combination with laser ther …
PURPOSE: Melasma remains a refractory skin condition that needs to be actively explored. Azelaic acid has been used for decade …
Efficacy of extended-release 45 mg oral minocycline and extended-release 45 mg oral minocycline plus 15% azelaic acid in the treatment of acne rosacea.
Jackson JM, Kircik LH, Lorenz DJ. Jackson JM, et al. J Drugs Dermatol. 2013 Mar;12(3):292-8. J Drugs Dermatol. 2013. PMID: 23545911 Clinical Trial.
This manuscript highlights the use of a new sustained-release low-dose minocycline 45 mg tablet, with or without azelaic acid, for the treatment of papulopustular rosacea....
This manuscript highlights the use of a new sustained-release low-dose minocycline 45 mg tablet, with or without azelaic acid, …
A comparison of the effectiveness of azelaic and pyruvic acid peels in the treatment of female adult acne: a randomized controlled trial.
Chilicka K, Rogowska AM, Szyguła R, Dzieńdziora-Urbińska I, Taradaj J. Chilicka K, et al. Sci Rep. 2020 Jul 28;10(1):12612. doi: 10.1038/s41598-020-69530-w. Sci Rep. 2020. PMID: 32724156 Free PMC article. Clinical Trial.
In the parallel clinical study design, one randomized group (n = 60, 50%) was treated using azelaic acid (AA), whereas the second group participated in pyruvic acid (PA) sessions. ...
In the parallel clinical study design, one randomized group (n = 60, 50%) was treated using azelaic acid (AA), whereas the sec …
Clinical and dermoscopic evaluation of combined (salicylic acid 20% and azelaic acid 20%) versus trichloroacetic acid 25% chemical peel in acne: an RCT.
Abdel Hay R, Hegazy R, Abdel Hady M, Saleh N. Abdel Hay R, et al. J Dermatolog Treat. 2019 Sep;30(6):572-577. doi: 10.1080/09546634.2018.1484876. Epub 2019 Mar 1. J Dermatolog Treat. 2019. PMID: 29862871 Free article. Clinical Trial.
Background: Combined azelaic acid (AA) and salicylic acid (SA) have not been previously used for acne. Objective: To compare the efficacy of this combination versus trichloroacetic acid (TCA) 25% peel in acne. ...
Background: Combined azelaic acid (AA) and salicylic acid (SA) have not been previously used for acne. Objective: To compare t …
Interventions for rosacea.
van Zuuren EJ, Fedorowicz Z, Carter B, van der Linden MM, Charland L. van Zuuren EJ, et al. Cochrane Database Syst Rev. 2015 Apr 28;2015(4):CD003262. doi: 10.1002/14651858.CD003262.pub5. Cochrane Database Syst Rev. 2015. PMID: 25919144 Free PMC article.
Physician assessments including investigators' global assessments, lesion counts and erythema were evaluated in three-quarters of the studies, but time needed for improvement and duration of remission were incompletely or not reported.The quality of the body of evidence was rated …
Physician assessments including investigators' global assessments, lesion counts and erythema were evaluated in three-quarters of the studie …
Interventions for rosacea.
van Zuuren EJ, Kramer S, Carter B, Graber MA, Fedorowicz Z. van Zuuren EJ, et al. Cochrane Database Syst Rev. 2011 Mar 16;(3):CD003262. doi: 10.1002/14651858.CD003262.pub4. Cochrane Database Syst Rev. 2011. Update in: Cochrane Database Syst Rev. 2015 Apr 28;(4):CD003262. doi: 10.1002/14651858.CD003262.pub5. PMID: 21412882 Updated.
Three trials provided data, based on participants' assessments, illustrating azelaic acid was more effective than placebo (RR 1.52, 95% CI 1.32 to 1.76).Physician-based assessments in two trials indicated that doxycycline appeared to be significantly more effective …
Three trials provided data, based on participants' assessments, illustrating azelaic acid was more effective than placebo (RR …
Interventions for rosacea.
van Zuuren EJ, Graber MA, Hollis S, Chaudhry M, Gupta AK, Gover M. van Zuuren EJ, et al. Cochrane Database Syst Rev. 2005 Jul 20;(3):CD003262. doi: 10.1002/14651858.CD003262.pub3. Cochrane Database Syst Rev. 2005. Update in: Cochrane Database Syst Rev. 2011 Mar 16;(3):CD003262. doi: 10.1002/14651858.CD003262.pub4. PMID: 16034895 Updated.
Data pooled from three between-patient trials showed a clear improvement in the azelaic acid group; the rates of treatment success were approximately 70 to 80% versus 50% to 55% (OR 2.45, 95% CI 1.82 to 3.28). ...There is evidence that topical metronidazole and a …
Data pooled from three between-patient trials showed a clear improvement in the azelaic acid group; the rates of treatment suc …
Azelaic acid 20% cream in the treatment of facial hyperpigmentation in darker-skinned patients.
Lowe NJ, Rizk D, Grimes P, Billips M, Pincus S. Lowe NJ, et al. Clin Ther. 1998 Sep-Oct;20(5):945-59. doi: 10.1016/s0149-2918(98)80076-3. Clin Ther. 1998. PMID: 9829446 Clinical Trial.

There was a significantly greater global improvement with azelaic acid than with vehicle at week 24 (P = 0.008). Azelaic acid produced a slightly but significantly greater amount of burning (weeks 4 and 12, P < or = 0.046) and stinging (week 4, P =

…
There was a significantly greater global improvement with azelaic acid than with vehicle at week 24 (P = 0.008). Azelaic …
Interventions for rosacea.
van Zuuren EJ, Graber MA, Hollis S, Chaudhry M, Gupta AK. van Zuuren EJ, et al. Cochrane Database Syst Rev. 2004;(1):CD003262. doi: 10.1002/14651858.CD003262.pub2. Cochrane Database Syst Rev. 2004. Update in: Cochrane Database Syst Rev. 2005 Jul 20;(3):CD003262. doi: 10.1002/14651858.CD003262.pub3. PMID: 14974010 Updated.
There is evidence that topical metronidazole and azelaic acid cream have a therapeutic effect. There is some evidence that oral metronidazole and tetracycline are effective. ...
There is evidence that topical metronidazole and azelaic acid cream have a therapeutic effect. There is some evidence that ora …
61 results