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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1987 3
1988 4
1989 3
1990 1
1991 1
1992 4
1993 7
1994 8
1995 6
1996 7
1997 11
1998 9
1999 6
2000 6
2001 6
2002 2
2003 7
2004 1
2005 1
2006 4
2007 4
2008 8
2009 4
2010 3
2011 4
2012 5
2013 5
2014 3
2015 2
2016 2
2017 2
2018 4
2019 3
2020 1
2021 1
2022 2
2023 1
2024 0

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147 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Early intervention with azelastine nasal spray may reduce viral load in SARS-CoV-2 infected patients.
Klussmann JP, Grosheva M, Meiser P, Lehmann C, Nagy E, Szijártó V, Nagy G, Konrat R, Flegel M, Holzer F, Groß D, Steinmetz C, Scherer B, Gruell H, Schlotz M, Klein F, de Aragão PA, Morr H, Al Saleh H, Bilstein A, Russo B, Müller-Scholtz S, Acikel C, Sahin H, Werkhäuser N, Allekotte S, Mösges R. Klussmann JP, et al. Sci Rep. 2023 Apr 26;13(1):6839. doi: 10.1038/s41598-023-32546-z. Sci Rep. 2023. PMID: 37100830 Free PMC article. Clinical Trial.
Ninety SARS-CoV-2 positive patients were randomized into 3 groups receiving placebo, 0.02% or 0.1% azelastine nasal spray for 11 days, during which viral loads were assessed by quantitative PCR. ...Comparable numbers of adverse events occurred in all treatment groups with …
Ninety SARS-CoV-2 positive patients were randomized into 3 groups receiving placebo, 0.02% or 0.1% azelastine nasal spray for 11 days …
Second-generation antihistamines: a comparative review.
Slater JW, Zechnich AD, Haxby DG. Slater JW, et al. Drugs. 1999 Jan;57(1):31-47. doi: 10.2165/00003495-199957010-00004. Drugs. 1999. PMID: 9951950
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofenadine, ketotifen, loratadine, mizolastine and terfenadine, for significant features that affect choice. ...
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofen …
Azelastine nasal spray in the management of seasonal allergic rhinitis.
Meltzer EO, Weiler JM, Dockhorn RJ, Widlitz MD, Freitag JJ. Meltzer EO, et al. Ann Allergy. 1994 Apr;72(4):354-9. Ann Allergy. 1994. PMID: 7908778 Clinical Trial.
Azelastine is capable of inhibiting both early-phase and late-phase allergic responses in animals and humans. ...Improvements in rhinitis symptoms were observed by the second hour after administration of azelastine and lasted up to 24 hours. The therapeutic effect o
Azelastine is capable of inhibiting both early-phase and late-phase allergic responses in animals and humans. ...Improvements in rhin
Comparison of azelastine and chlorpheniramine in the treatment of mastocytosis.
Friedman BS, Santiago ML, Berkebile C, Metcalfe DD. Friedman BS, et al. J Allergy Clin Immunol. 1993 Oct;92(4):520-6. doi: 10.1016/0091-6749(93)90076-r. J Allergy Clin Immunol. 1993. PMID: 8104966 Clinical Trial.
RESULTS: Subjects' mean wheal area responses provoked by histamine or morphine sulfate were significantly lowered by azelastine when compared with chlorpheniramine. Plasma histamine levels in subjects receiving azelastine or chlorpheniramine were not significantly d …
RESULTS: Subjects' mean wheal area responses provoked by histamine or morphine sulfate were significantly lowered by azelastine when …
Intranasal Azelastine and Fluticasone as Combination Therapy for Allergic Rhinitis: Systematic Review and Meta-analysis.
Debbaneh PM, Bareiss AK, Wise SK, McCoul ED. Debbaneh PM, et al. Otolaryngol Head Neck Surg. 2019 Sep;161(3):412-418. doi: 10.1177/0194599819841883. Epub 2019 Apr 9. Otolaryngol Head Neck Surg. 2019. PMID: 30961435
OBJECTIVE: Combination therapy with intranasal azelastine and fluticasone propionate is an option for treatment of allergic rhinitis. ...CONCLUSION: Current evidence supports both efficacy and superiority of combination intranasal azelastine and fluticasone in reduc …
OBJECTIVE: Combination therapy with intranasal azelastine and fluticasone propionate is an option for treatment of allergic rhinitis. …
Azelastine eye drops in the treatment of perennial allergic conjunctivitis.
Nazarov O, Petzold U, Haase H, Nguyen DT, Ellers-Lenz B, Hermann R. Nazarov O, et al. Arzneimittelforschung. 2003;53(3):167-73. doi: 10.1055/s-0031-1297090. Arzneimittelforschung. 2003. PMID: 12705171 Clinical Trial.
Azelastine significantly improved itching and conjunctival redness versus placebo (p < 0.001). ...On Day 7, ocular symptoms score improved by 1.5 +/- 0.9 (versus 0.5 +/- 0.8 placebo) with score improvement > or = 2 in 55% with azelastine (versus 14% placebo).
Azelastine significantly improved itching and conjunctival redness versus placebo (p < 0.001). ...On Day 7, ocular symptoms score
Topical azelastine in perennial allergic conjunctivitis.
Canonica GW, Ciprandi G, Petzold U, Kolb C, Ellers-Lenz B, Hermann R. Canonica GW, et al. Curr Med Res Opin. 2003;19(4):321-9. doi: 10.1185/030079903125001794. Curr Med Res Opin. 2003. PMID: 12841925 Clinical Trial.
The present study aimed to evaluate azelastine eye drops in patients with PAC compared to placebo. RESEARCH DESIGN AND METHODS: A multinational trial in 22 centres randomised 139 patients to twice-daily treatment for 6 weeks with masked 0.05% azelastine eye drops, m …
The present study aimed to evaluate azelastine eye drops in patients with PAC compared to placebo. RESEARCH DESIGN AND METHODS: A mul …
Azelastine eye-drops in seasonal allergic conjunctivitis or rhinoconjunctivitis. A double-blind, randomized, placebo-controlled study.
Giede-Tuch C, Westhoff M, Zarth A. Giede-Tuch C, et al. Allergy. 1998 Sep;53(9):857-62. doi: 10.1111/j.1398-9995.1998.tb03991.x. Allergy. 1998. PMID: 9788686 Clinical Trial.
One patient each from the two azelastine groups and three from the placebo group withdrew because of inefficacy. ...Azelastine eye-drops are effective and well tolerated at a dose of 0.05% for the treatment of seasonal allergic conjunctivitis....
One patient each from the two azelastine groups and three from the placebo group withdrew because of inefficacy. ...Azelastine
Azelastine nasal spray and desloratadine tablets in pollen-induced seasonal allergic rhinitis: a pharmacodynamic study of onset of action and efficacy.
Horak F, Zieglmayer UP, Zieglmayer R, Kavina A, Marschall K, Munzel U, Petzold U. Horak F, et al. Curr Med Res Opin. 2006 Jan;22(1):151-7. doi: 10.1185/030079906X80305. Curr Med Res Opin. 2006. PMID: 16393441 Clinical Trial.
Decrease both in Major Nasal Symptom Score (MNSS) and in Total Nasal Symptom Score (TNSS) was fastest after azelastine treatment. Improvement of nasal symptom severity was most pronounced after azelastine treatment for all nasal symptoms including nasal congestion. …
Decrease both in Major Nasal Symptom Score (MNSS) and in Total Nasal Symptom Score (TNSS) was fastest after azelastine treatment. Imp …
Pharmacodynamic evaluation of azelastine in subjects with asthma.
Spector SL, Perhach JL, Rohr AS, Rachelefsky GS, Katz RM, Siegel SC. Spector SL, et al. J Allergy Clin Immunol. 1987 Jul;80(1):75-80. doi: 10.1016/s0091-6749(87)80194-x. J Allergy Clin Immunol. 1987. PMID: 3298379 Clinical Trial.
A broad antiallergic compound called azelastine was studied pharmacodynamically in 34 subjects to correlate bronchodilator effect with blood levels of azelastine and desmethyl azelastine, its major metabolic product in man. Despite azelastine and desme …
A broad antiallergic compound called azelastine was studied pharmacodynamically in 34 subjects to correlate bronchodilator effect wit …
147 results