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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1981 1
1983 2
1984 2
1986 4
1987 3
1988 3
1989 4
1990 2
1991 7
1992 13
1993 7
1994 18
1995 18
1996 23
1997 10
1998 17
1999 19
2000 22
2001 32
2002 25
2003 36
2004 34
2005 30
2006 25
2007 38
2008 29
2009 42
2010 37
2011 43
2012 54
2013 58
2014 59
2015 75
2016 82
2017 68
2018 86
2019 90
2020 39
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1,024 results
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Page 1
Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial.
Akkasheh G, Kashani-Poor Z, Tajabadi-Ebrahimi M, Jafari P, Akbari H, Taghizadeh M, Memarzadeh MR, Asemi Z, Esmaillzadeh A. Akkasheh G, et al. Nutrition. 2016 Mar;32(3):315-20. doi: 10.1016/j.nut.2015.09.003. Epub 2015 Sep 28. Nutrition. 2016. PMID: 26706022 Clinical Trial.
Additionally, taking probiotics resulted in a significant rise in plasma total glutathione levels (1.8 ± 83.1 vs. -106.8 ± 190.7 μmol/L, P = 0.02) compared with the placebo. ...CONCLUSIONS: Probiotic administration in patients with MDD for 8 wk had beneficial effect …
Additionally, taking probiotics resulted in a significant rise in plasma total glutathione levels (1.8 ± 83.1 vs. -106.8 ± 190 …
Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function.
Sinha R, Sinha I, Calcagnotto A, Trushin N, Haley JS, Schell TD, Richie JP Jr. Sinha R, et al. Eur J Clin Nutr. 2018 Jan;72(1):105-111. doi: 10.1038/ejcn.2017.132. Epub 2017 Aug 30. Eur J Clin Nutr. 2018. PMID: 28853742 Free PMC article.
BACKGROUND/OBJECTIVES: Glutathione (GSH) is the most abundant endogenous antioxidant and a critical regulator of oxidative stress. Maintenance of optimal tissues for GSH levels may be an important strategy for the prevention of oxidative stress-related diseases. ...
BACKGROUND/OBJECTIVES: Glutathione (GSH) is the most abundant endogenous antioxidant and a critical regulator of oxidative stress. Ma …
A major role for ferroptosis in Mycobacterium tuberculosis-induced cell death and tissue necrosis.
Amaral EP, Costa DL, Namasivayam S, Riteau N, Kamenyeva O, Mittereder L, Mayer-Barber KD, Andrade BB, Sher A. Amaral EP, et al. J Exp Med. 2019 Mar 4;216(3):556-570. doi: 10.1084/jem.20181776. Epub 2019 Feb 20. J Exp Med. 2019. PMID: 30787033 Free PMC article.
We observed that Mtb-induced macrophage necrosis is associated with reduced levels of glutathione and glutathione peroxidase-4 (Gpx4), along with increased free iron, mitochondrial superoxide, and lipid peroxidation, all of which are important hallmarks of fe …
We observed that Mtb-induced macrophage necrosis is associated with reduced levels of glutathione and glutathione perox …
A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity.
Cao JY, Poddar A, Magtanong L, Lumb JH, Mileur TR, Reid MA, Dovey CM, Wang J, Locasale JW, Stone E, Cole SPC, Carette JE, Dixon SJ. Cao JY, et al. Cell Rep. 2019 Feb 5;26(6):1544-1556.e8. doi: 10.1016/j.celrep.2019.01.043. Cell Rep. 2019. PMID: 30726737 Free PMC article.
Using genome-wide human haploid genetic screening technology coupled to fluorescence-activated cell sorting (FACS), we directly identify genes that regulate intracellular glutathione abundance and characterize their role in ferroptosis regulation. ...By contrast, di …
Using genome-wide human haploid genetic screening technology coupled to fluorescence-activated cell sorting (FACS), we directly ident …
Genotoxic stress-triggered β-catenin/JDP2/PRMT5 complex facilitates reestablishing glutathione homeostasis.
Cao L, Wu G, Zhu J, Tan Z, Shi D, Wu X, Tang M, Li Z, Hu Y, Zhang S, Yu R, Mo S, Wu J, Song E, Li M, Song L, Li J. Cao L, et al. Nat Commun. 2019 Aug 21;10(1):3761. doi: 10.1038/s41467-019-11696-7. Nat Commun. 2019. PMID: 31434880 Free PMC article.
Treatment with OICR-9429, a small-molecule antagonist of the WDR5-MLL interaction, inhibits the β-catenin/JDP2/PRMT5 complex-reestablished GSH metabolism, leading to a lethal increase in the already-elevated levels of ROS in the genotoxic-agent treated cancer cells. ...
Treatment with OICR-9429, a small-molecule antagonist of the WDR5-MLL interaction, inhibits the β-catenin/JDP2/PRMT5 complex-reestablished G …
Microbial antioxidant defense enzymes.
Staerck C, Gastebois A, Vandeputte P, Calenda A, Larcher G, Gillmann L, Papon N, Bouchara JP, Fleury MJJ. Staerck C, et al. Microb Pathog. 2017 Sep;110:56-65. doi: 10.1016/j.micpath.2017.06.015. Epub 2017 Jun 16. Microb Pathog. 2017. PMID: 28629723 Review.
ROS and RNS are highly reactive species with potentially harmful effects on any cellular components (lipids, proteins and nucleic acids) when produced with a high level. ...Bacteria, fungi and parasites also display similar enzymatic activities to escape the host ox …
ROS and RNS are highly reactive species with potentially harmful effects on any cellular components (lipids, proteins and nucleic acids) whe …
Targeted interplay between bacterial pathogens and host autophagy.
Sudhakar P, Jacomin AC, Hautefort I, Samavedam S, Fatemian K, Ari E, Gul L, Demeter A, Jones E, Korcsmaros T, Nezis IP. Sudhakar P, et al. Autophagy. 2019 Sep;15(9):1620-1633. doi: 10.1080/15548627.2019.1590519. Epub 2019 Mar 25. Autophagy. 2019. PMID: 30909843 Free PMC article.
Despite previous key findings of bacteria-autophagy interplay, asystems-level insight into selective targeting by the host and autophagy modulation by the pathogens is lacking. ...Abbreviations: ATG5: autophagy related 5; CALCOCO2/NDP52: calcium binding and coiled-c …
Despite previous key findings of bacteria-autophagy interplay, asystems-level insight into selective targeting by the host and …
The Effects of Synbiotic Supplementation on Pregnancy Outcomes in Gestational Diabetes.
Karamali M, Nasiri N, Taghavi Shavazi N, Jamilian M, Bahmani F, Tajabadi-Ebrahimi M, Asemi Z. Karamali M, et al. Probiotics Antimicrob Proteins. 2018 Sep;10(3):496-503. doi: 10.1007/s12602-017-9313-7. Probiotics Antimicrob Proteins. 2018. PMID: 28786012 Clinical Trial.
. - 19.7 ± 124.6 mmol/L, P = 0.009) and total glutathione (GSH) levels (+ 28.7 ± 61.5 vs. - 14.9 ± 85.3 μmol/L, P = 0.02). Supplementation with synbiotic had a significant decrease in cesarean section rate (16.7 vs. 40.0%, P = 0.04), lower incidence of hyperbilirubi …
. - 19.7 ± 124.6 mmol/L, P = 0.009) and total glutathione (GSH) levels (+ 28.7 ± 61.5 vs. - 14.9 ± 85.3 μmol/L, P = 0.02). Sup …
Clinical and metabolic response to probiotic supplementation in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled trial.
Kouchaki E, Tamtaji OR, Salami M, Bahmani F, Daneshvar Kakhaki R, Akbari E, Tajabadi-Ebrahimi M, Jafari P, Asemi Z. Kouchaki E, et al. Clin Nutr. 2017 Oct;36(5):1245-1249. doi: 10.1016/j.clnu.2016.08.015. Epub 2016 Sep 16. Clin Nutr. 2017. PMID: 27669638 Clinical Trial.
. -0.005 ± 0.01, P < 0.001) and HDL-cholesterol levels (2.7 ± 3.4 vs. 0.9 ± 2.9 mg/dL, P = 0.02) compared with the placebo. CONCLUSIONS: Our study demonstrated that the use of probiotic capsule for 12 weeks among subjects with MS had favorable effects on EDSS, parameter …
. -0.005 ± 0.01, P < 0.001) and HDL-cholesterol levels (2.7 ± 3.4 vs. 0.9 ± 2.9 mg/dL, P = 0.02) compared with the placebo. CONCLU …
Modulation of gut microbiota by mulberry fruit polysaccharide treatment of obese diabetic db/db mice.
Chen C , You LJ , Huang Q , Fu X , Zhang B , Liu RH , Li C . Chen C , et al. Food Funct. 2018 Jul 17;9(7):3732-3742. doi: 10.1039/c7fo01346a. Food Funct. 2018. PMID: 29995048
Furthermore, our data showed increased enzymatic activities as evidenced by parameters such as superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT). ...Especially at the genus level, the enrichment of some key bacteria like Bacteroi …
Furthermore, our data showed increased enzymatic activities as evidenced by parameters such as superoxide dismutase (SOD), glutathione
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