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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1981 1
1983 2
1984 2
1986 4
1987 3
1988 3
1989 4
1990 2
1991 7
1992 13
1993 7
1994 18
1995 18
1996 23
1997 10
1998 17
1999 19
2000 22
2001 32
2002 25
2003 36
2004 34
2005 30
2006 25
2007 38
2008 29
2009 42
2010 37
2011 44
2012 54
2013 58
2014 59
2015 75
2016 82
2017 68
2018 87
2019 93
2020 98
2021 75
2022 74
2023 78
2024 75

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1,347 results

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Page 1
A major role for ferroptosis in Mycobacterium tuberculosis-induced cell death and tissue necrosis.
Amaral EP, Costa DL, Namasivayam S, Riteau N, Kamenyeva O, Mittereder L, Mayer-Barber KD, Andrade BB, Sher A. Amaral EP, et al. J Exp Med. 2019 Mar 4;216(3):556-570. doi: 10.1084/jem.20181776. Epub 2019 Feb 20. J Exp Med. 2019. PMID: 30787033 Free PMC article.
We observed that Mtb-induced macrophage necrosis is associated with reduced levels of glutathione and glutathione peroxidase-4 (Gpx4), along with increased free iron, mitochondrial superoxide, and lipid peroxidation, all of which are important hallmarks of fe …
We observed that Mtb-induced macrophage necrosis is associated with reduced levels of glutathione and glutathione perox …
Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial.
Akkasheh G, Kashani-Poor Z, Tajabadi-Ebrahimi M, Jafari P, Akbari H, Taghizadeh M, Memarzadeh MR, Asemi Z, Esmaillzadeh A. Akkasheh G, et al. Nutrition. 2016 Mar;32(3):315-20. doi: 10.1016/j.nut.2015.09.003. Epub 2015 Sep 28. Nutrition. 2016. PMID: 26706022 Clinical Trial.
Additionally, taking probiotics resulted in a significant rise in plasma total glutathione levels (1.8 83.1 vs. -106.8 190.7 mumol/L, P = 0.02) compared with the placebo. We did not find any significant change in fasting plasma glucose, homeostatic model assessment …
Additionally, taking probiotics resulted in a significant rise in plasma total glutathione levels (1.8 83.1 vs. -106.8 190.7 m …
Role of Glutathione in Cancer: From Mechanisms to Therapies.
Kennedy L, Sandhu JK, Harper ME, Cuperlovic-Culf M. Kennedy L, et al. Biomolecules. 2020 Oct 9;10(10):1429. doi: 10.3390/biom10101429. Biomolecules. 2020. PMID: 33050144 Free PMC article. Review.
Glutathione (GSH) is the most abundant non-protein thiol present at millimolar concentrations in mammalian tissues. ...Although in healthy cells it is crucial for the removal and detoxification of carcinogens, elevated GSH levels in tumor cells are associated with t …
Glutathione (GSH) is the most abundant non-protein thiol present at millimolar concentrations in mammalian tissues. ...Although in he …
Aluminum, Arsenic, Beryllium, Cadmium, Chromium, Cobalt, Copper, Iron, Lead, Mercury, Molybdenum, Nickel, Platinum, Thallium, Titanium, Vanadium, and Zinc: Molecular Aspects in Experimental Liver Injury.
Teschke R. Teschke R. Int J Mol Sci. 2022 Oct 13;23(20):12213. doi: 10.3390/ijms232012213. Int J Mol Sci. 2022. PMID: 36293069 Free PMC article. Review.
NiCl(2) causes increased iron deposition in the liver, upregulation of cyclooxygenase 2 (COX-2) protein and mRNA expression levels, downregulation of glutathione eroxidase 4 (GPX4), ferritin heavy chain 1 (FTH1), nuclear receptor coactivator 4 (NCOA4) protein, and m …
NiCl(2) causes increased iron deposition in the liver, upregulation of cyclooxygenase 2 (COX-2) protein and mRNA expression levels, d …
Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function.
Sinha R, Sinha I, Calcagnotto A, Trushin N, Haley JS, Schell TD, Richie JP Jr. Sinha R, et al. Eur J Clin Nutr. 2018 Jan;72(1):105-111. doi: 10.1038/ejcn.2017.132. Epub 2017 Aug 30. Eur J Clin Nutr. 2018. PMID: 28853742 Free PMC article.
BACKGROUND/OBJECTIVES: Glutathione (GSH) is the most abundant endogenous antioxidant and a critical regulator of oxidative stress. Maintenance of optimal tissues for GSH levels may be an important strategy for the prevention of oxidative stress-related diseases. ...
BACKGROUND/OBJECTIVES: Glutathione (GSH) is the most abundant endogenous antioxidant and a critical regulator of oxidative stress. Ma …
Multiomics Analysis Reveals Aberrant Metabolism and Immunity Linked Gut Microbiota with Insomnia.
Wang Q, Chen B, Sheng D, Yang J, Fu S, Wang J, Zhao C, Wang Y, Gai X, Wang J, Stirling K, Heng X, Man H, Zhang L. Wang Q, et al. Microbiol Spectr. 2022 Oct 26;10(5):e0099822. doi: 10.1128/spectrum.00998-22. Epub 2022 Oct 3. Microbiol Spectr. 2022. PMID: 36190400 Free PMC article.
Moreover, we found that IL-1beta levels were significantly higher in insomnia patients while TNF-alpha was significantly reduced. We further identified that the changes in the level of IL-1beta and TNF-alpha were associated with some specific bacteria and met …
Moreover, we found that IL-1beta levels were significantly higher in insomnia patients while TNF-alpha was significantly reduced. We …
Akkermansia muciniphila Ameliorates Acetaminophen-Induced Liver Injury by Regulating Gut Microbial Composition and Metabolism.
Xia J, Lv L, Liu B, Wang S, Zhang S, Wu Z, Yang L, Bian X, Wang Q, Wang K, Zhuge A, Li S, Yan R, Jiang H, Xu K, Li L. Xia J, et al. Microbiol Spectr. 2022 Feb 23;10(1):e0159621. doi: 10.1128/spectrum.01596-21. Epub 2022 Feb 2. Microbiol Spectr. 2022. PMID: 35107323 Free PMC article.
Administration of A. muciniphila efficiently alleviated APAP-induced hepatotoxicity and reduced the levels of serum alanine aminotransferase (ALT) and aspartate transaminase (AST). A. muciniphila significantly attenuated APAP-induced oxidative stress and the inflammatory r …
Administration of A. muciniphila efficiently alleviated APAP-induced hepatotoxicity and reduced the levels of serum alanine aminotran …
2-Deoxy-d-ribose induces ferroptosis in renal tubular epithelial cells via ubiquitin-proteasome system-mediated xCT protein degradation.
Kim M, Bae JY, Yoo S, Kim HW, Lee SA, Kim ET, Koh G. Kim M, et al. Free Radic Biol Med. 2023 Nov 1;208:384-393. doi: 10.1016/j.freeradbiomed.2023.08.027. Epub 2023 Sep 1. Free Radic Biol Med. 2023. PMID: 37659699 Free article.
Recent findings suggest that inhibiting system chic-induces ferroptosis by reducing intracellular cystine levels, and that ferroptosis in renal tubular epithelial cells (RTECs) contributes to acute kidney injury (AKI) and diabetic nephropathy. ...This study aimed to invest …
Recent findings suggest that inhibiting system chic-induces ferroptosis by reducing intracellular cystine levels, and that ferroptosi …
Glutathione and infection.
Morris D, Khurasany M, Nguyen T, Kim J, Guilford F, Mehta R, Gray D, Saviola B, Venketaraman V. Morris D, et al. Biochim Biophys Acta. 2013 May;1830(5):3329-49. doi: 10.1016/j.bbagen.2012.10.012. Epub 2012 Oct 23. Biochim Biophys Acta. 2013. PMID: 23089304 Review.
BACKGROUND: The tripeptide gamma-glutamylcysteinylglycine or glutathione (GSH) has demonstrated protective abilities against the detrimental effects of oxidative stress within the human body, as well as protection against infection by exogenous microbial organisms. …
BACKGROUND: The tripeptide gamma-glutamylcysteinylglycine or glutathione (GSH) has demonstrated protective abilities against the detr …
Cancer-associated fibroblasts reprogram cysteine metabolism to increase tumor resistance to ferroptosis in pancreatic cancer.
Zhu Y, Fang S, Fan B, Xu K, Xu L, Wang L, Zhu L, Chen C, Wu R, Ni J, Wang J. Zhu Y, et al. Theranostics. 2024 Feb 11;14(4):1683-1700. doi: 10.7150/thno.89805. eCollection 2024. Theranostics. 2024. PMID: 38389839 Free PMC article.
The effects of exogenous cysteine intake were examined in a mouse xenograft model and the effects of the cysteine pathway on ferroptosis in PDAC were investigated by western blotting, measurement of glutathione and reactive oxygen species levels, among others. Resul …
The effects of exogenous cysteine intake were examined in a mouse xenograft model and the effects of the cysteine pathway on ferroptosis in …
1,347 results