Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 4
2004 3
2005 1
2006 2
2007 1
2008 3
2009 3
2010 2
2011 3
2012 2
2013 2
2014 1
2015 3
2017 1
2021 0
Text availability
Article attribute
Article type
Publication date

Search Results

31 results
Results by year
Filters applied: . Clear all
Page 1
The use of molecular beacons to detect and quantify microRNA.
Baker MB, Bao G, Searles CD. Baker MB, et al. Among authors: bao g. Methods Mol Biol. 2013;1039:279-87. doi: 10.1007/978-1-62703-535-4_22. Methods Mol Biol. 2013. PMID: 24026703
Molecular beacons are oligonucleotide (DNA or RNA) probes that have become increasingly important tools for RNA sensitive detection both in vitro and in living cells. ...Our group has performed extensive studies on molecular beacon design, molecular …
Molecular beacons are oligonucleotide (DNA or RNA) probes that have become increasingly important tools for RNA sensitive dete …
Delivery of molecular beacons for live-cell imaging and analysis of RNA.
Chen AK, Rhee WJ, Bao G, Tsourkas A. Chen AK, et al. Among authors: bao g. Methods Mol Biol. 2011;714:159-74. doi: 10.1007/978-1-61779-005-8_10. Methods Mol Biol. 2011. PMID: 21431740
As a result of their favorable fluorescent enhancement and their high specificity, molecular beacons have been used for a wide range of applications, including the monitoring of RNA expression and localization in living cells, cancer cell detection, and the study of …
As a result of their favorable fluorescent enhancement and their high specificity, molecular beacons have been used for a wide …
Molecular beacons can assess changes in expression and 3'-polyadenylation of human eNOS mRNA.
Jones R, Baker MB, Weber M, Harrison DG, Bao G, Searles CD. Jones R, et al. Among authors: bao g. Am J Physiol Cell Physiol. 2009 Mar;296(3):C498-504. doi: 10.1152/ajpcell.00462.2008. Epub 2008 Dec 24. Am J Physiol Cell Physiol. 2009. PMID: 19109525 Free PMC article.
Single- and dual-fluorescence resonance energy transfer (FRET) molecular beacon hybridization assays were developed to measure changes in mRNA levels and 3'-polyadenylation, respectively, in primary human endothelial cell cultures subjected to laminar shear stress o …
Single- and dual-fluorescence resonance energy transfer (FRET) molecular beacon hybridization assays were developed to measure …
Hybridization kinetics and thermodynamics of molecular beacons.
Tsourkas A, Behlke MA, Rose SD, Bao G. Tsourkas A, et al. Among authors: bao g. Nucleic Acids Res. 2003 Feb 15;31(4):1319-30. doi: 10.1093/nar/gkg212. Nucleic Acids Res. 2003. PMID: 12582252 Free PMC article.
To fully realize the potential of molecular beacons, it is necessary to optimize their structure. Here we report a systematic study of the thermodynamic and kinetic parameters that describe the molecular beacon structure-function relationship. ...Mo …
To fully realize the potential of molecular beacons, it is necessary to optimize their structure. Here we report a systematic …
Peptide-linked molecular beacons for efficient delivery and rapid mRNA detection in living cells.
Nitin N, Santangelo PJ, Kim G, Nie S, Bao G. Nitin N, et al. Among authors: bao g. Nucleic Acids Res. 2004 Apr 14;32(6):e58. doi: 10.1093/nar/gnh063. Nucleic Acids Res. 2004. PMID: 15084673 Free PMC article.
We conjugated the TAT peptide to molecular beacons using three different linkages and demonstrated that, at relatively low concentrations, these molecular beacon constructs were internalized into living cells within 30 min with nearly 100% efficiency. …
We conjugated the TAT peptide to molecular beacons using three different linkages and demonstrated that, at relatively low con …
Hybridization of 2'-O-methyl and 2'-deoxy molecular beacons to RNA and DNA targets.
Tsourkas A, Behlke MA, Bao G. Tsourkas A, et al. Among authors: bao g. Nucleic Acids Res. 2002 Dec 1;30(23):5168-74. Nucleic Acids Res. 2002. PMID: 12466541 Free PMC article. Corrected and republished.
The improved stability of the 2'-O-methyl/RNA duplex was accompanied by a slightly reduced specificity compared with the duplex of 2'-deoxy molecular beacons and RNA targets. However, the 2'-O-methyl molecular beacons hybridized to RNA more quickly tha …
The improved stability of the 2'-O-methyl/RNA duplex was accompanied by a slightly reduced specificity compared with the duplex of 2'-deoxy …
Structure-function relationships of shared-stem and conventional molecular beacons.
Tsourkas A, Behlke MA, Bao G. Tsourkas A, et al. Among authors: bao g. Nucleic Acids Res. 2002 Oct 1;30(19):4208-15. doi: 10.1093/nar/gkf536. Nucleic Acids Res. 2002. PMID: 12364599 Free PMC article.
Here we report the design of shared-stem molecular beacons with one arm participating in both stem formation when the beacon is closed and target hybridization when it is open. ...Shared-stem molecular beacons form more stable duplexes with targ …
Here we report the design of shared-stem molecular beacons with one arm participating in both stem formation when the beaco …
Engineering imaging probes and molecular machines for nanomedicine.
Tong S, Cradick TJ, Ma Y, Dai Z, Bao G. Tong S, et al. Among authors: bao g. Sci China Life Sci. 2012 Oct;55(10):843-61. doi: 10.1007/s11427-012-4380-1. Epub 2012 Oct 31. Sci China Life Sci. 2012. PMID: 23108862 Review.
Recent advances in nanomedicine include the development of functional nanoparticle based molecular imaging probes, nano-structured materials as drug/gene carriers for in vivo delivery, and engineered molecular machines for treating single-gene disorders. This review …
Recent advances in nanomedicine include the development of functional nanoparticle based molecular imaging probes, nano-structured ma …
Live-cell characterization and analysis of a clinical isolate of bovine respiratory syncytial virus, using molecular beacons.
Santangelo P, Nitin N, LaConte L, Woolums A, Bao G. Santangelo P, et al. Among authors: bao g. J Virol. 2006 Jan;80(2):682-8. doi: 10.1128/JVI.80.2.682-688.2006. J Virol. 2006. PMID: 16378971 Free PMC article.
Molecular beacons are dual-labeled, hairpin oligonucleotide probes with a reporter fluorophore at one end and a quencher at the other; they are designed to fluoresce only when hybridizing to a complementary target. ...Low background in uninfected cells and simultane …
Molecular beacons are dual-labeled, hairpin oligonucleotide probes with a reporter fluorophore at one end and a quencher at th …
Target accessibility and signal specificity in live-cell detection of BMP-4 mRNA using molecular beacons.
Rhee WJ, Santangelo PJ, Jo H, Bao G. Rhee WJ, et al. Among authors: bao g. Nucleic Acids Res. 2008 Mar;36(5):e30. doi: 10.1093/nar/gkn039. Epub 2008 Feb 14. Nucleic Acids Res. 2008. PMID: 18276638 Free PMC article.
We carried out an extensive study of the target accessibility of BMP-4 mRNA using 10 different designs of molecular beacons (MBs), and identified the optimal beacon design. ...We found that fluorescence signal from MBs depends critically on target sequences; …
We carried out an extensive study of the target accessibility of BMP-4 mRNA using 10 different designs of molecular beacons (M …
31 results