Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2009 5
2010 1
2011 1
2012 1
2013 1
2014 2
2015 1
2016 4
2017 4
2018 5
2019 4
2020 0
Text availability
Article attribute
Article type
Publication date

Search Results

29 results
Results by year
Filters applied: . Clear all
Page 1
Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells.
Han S, Fink J, Jörg DJ, Lee E, Yum MK, Chatzeli L, Merker SR, Josserand M, Trendafilova T, Andersson-Rolf A, Dabrowska C, Kim H, Naumann R, Lee JH, Sasaki N, Mort RL, Basak O, Clevers H, Stange DE, Philpott A, Kim JK, Simons BD, Koo BK. Han S, et al. Among authors: Basak O. Cell Stem Cell. 2019 Sep 5;25(3):342-356.e7. doi: 10.1016/j.stem.2019.07.008. Epub 2019 Aug 15. Cell Stem Cell. 2019. PMID: 31422913 Free PMC article.
Several markers have been proposed for gastric corpus stem cells in both isthmus and base regions. However, the identity of isthmus stem cells (IsthSCs) and the interaction between distinct stem cell populations is still under debate. ...Finally, single-ce
Several markers have been proposed for gastric corpus stem cells in both isthmus and base regions. However, the identity of isthmus s …
Profiling proliferative cells and their progeny in damaged murine hearts.
Kretzschmar K, Post Y, Bannier-Hélaouët M, Mattiotti A, Drost J, Basak O, Li VSW, van den Born M, Gunst QD, Versteeg D, Kooijman L, van der Elst S, van Es JH, van Rooij E, van den Hoff MJB, Clevers H. Kretzschmar K, et al. Among authors: Basak O. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12245-E12254. doi: 10.1073/pnas.1805829115. Epub 2018 Dec 7. Proc Natl Acad Sci U S A. 2018. PMID: 30530645 Free PMC article.
By single-cell mRNA sequencing and genetic lineage tracing using two Ki67 knockin mouse models, we map all proliferating cells and their progeny in homoeostatic and regenerating murine hearts. Cycling cardiomyocytes were only robustly observed in the early postnatal …
By single-cell mRNA sequencing and genetic lineage tracing using two Ki67 knockin mouse models, we map all proliferating cells
Programs for the persistence, vigilance and control of human CD8(+) lung-resident memory T cells.
Hombrink P, Helbig C, Backer RA, Piet B, Oja AE, Stark R, Brasser G, Jongejan A, Jonkers RE, Nota B, Basak O, Clevers HC, Moerland PD, Amsen D, van Lier RA. Hombrink P, et al. Among authors: Basak O. Nat Immunol. 2016 Dec;17(12):1467-1478. doi: 10.1038/ni.3589. Epub 2016 Oct 24. Nat Immunol. 2016. PMID: 27776108
Tissue-resident memory T cells (T(RM) cells) in the airways mediate protection against respiratory infection. We characterized T(RM) cells expressing integrin α(E) (CD103) that reside within the epithelial barrier of human lungs. ...A distinct set of transcri …
Tissue-resident memory T cells (T(RM) cells) in the airways mediate protection against respiratory infection. We characterized …
Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy.
Basak O, Krieger TG, Muraro MJ, Wiebrands K, Stange DE, Frias-Aldeguer J, Rivron NC, van de Wetering M, van Es JH, van Oudenaarden A, Simons BD, Clevers H. Basak O, et al. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E610-E619. doi: 10.1073/pnas.1715911114. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311336 Free PMC article.
This behavior is best explained by stochastic fate decisions, where stem-cell number within a shared niche fluctuates over time. Fate mapping proliferating cells using a Ki67(iresCreER) allele confirms that active NSCs reversibly return to quiescence, achieving long …
This behavior is best explained by stochastic fate decisions, where stem-cell number within a shared niche fluctuates over time. Fate …
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids.
Hu H, Gehart H, Artegiani B, LÖpez-Iglesias C, Dekkers F, Basak O, van Es J, Chuva de Sousa Lopes SM, Begthel H, Korving J, van den Born M, Zou C, Quirk C, Chiriboga L, Rice CM, Ma S, Rios A, Peters PJ, de Jong YP, Clevers H. Hu H, et al. Among authors: Basak O. Cell. 2018 Nov 29;175(6):1591-1606.e19. doi: 10.1016/j.cell.2018.11.013. Cell. 2018. PMID: 30500538 Free article.
Two modes of damage response have been described: (1) The "oval cell" response emanates from the biliary tree when all hepatocytes are affected by chronic liver disease. (2) A massive, proliferative response of mature hepatocytes occurs upon acute liver damage such as part …
Two modes of damage response have been described: (1) The "oval cell" response emanates from the biliary tree when all hepatocytes ar …
Single-cell messenger RNA sequencing reveals rare intestinal cell types.
Grün D, Lyubimova A, Kester L, Wiebrands K, Basak O, Sasaki N, Clevers H, van Oudenaarden A. Grün D, et al. Among authors: Basak O. Nature. 2015 Sep 10;525(7568):251-5. doi: 10.1038/nature14966. Epub 2015 Aug 19. Nature. 2015. PMID: 26287467
Identifying rare cell types, such as stem cells, short-lived progenitors, cancer stem cells, or circulating tumour cells, is crucial to acquire a better understanding of normal or diseased tissue biology. ...We demonstrate that this algorithm can resol …
Identifying rare cell types, such as stem cells, short-lived progenitors, cancer stem cells, or circulating tumour c
Visualization of a short-range Wnt gradient in the intestinal stem-cell niche.
Farin HF, Jordens I, Mosa MH, Basak O, Korving J, Tauriello DV, de Punder K, Angers S, Peters PJ, Maurice MM, Clevers H. Farin HF, et al. Among authors: Basak O. Nature. 2016 Feb 18;530(7590):340-3. doi: 10.1038/nature16937. Epub 2016 Feb 10. Nature. 2016. PMID: 26863187
Wnt3 is produced specifically by Paneth cells. Here we have generated an epitope-tagged, functional Wnt3 knock-in allele. Wnt3 covers basolateral membranes of neighbouring stem cells. ...By manipulating Wnt3 secretion and by arresting stem-cell proliferation, …
Wnt3 is produced specifically by Paneth cells. Here we have generated an epitope-tagged, functional Wnt3 knock-in allele. Wnt3 covers …
Induced Quiescence of Lgr5+ Stem Cells in Intestinal Organoids Enables Differentiation of Hormone-Producing Enteroendocrine Cells.
Basak O, Beumer J, Wiebrands K, Seno H, van Oudenaarden A, Clevers H. Basak O, et al. Cell Stem Cell. 2017 Feb 2;20(2):177-190.e4. doi: 10.1016/j.stem.2016.11.001. Epub 2016 Dec 8. Cell Stem Cell. 2017. PMID: 27939219 Free article.
Lgr5+ adult intestinal stem cells are highly proliferative throughout life. Single Lgr5+ stem cells can be cultured into three-dimensional organoids containing all intestinal epithelial cell types at near-normal ratios. Conditions to generate the main cell
Lgr5+ adult intestinal stem cells are highly proliferative throughout life. Single Lgr5+ stem cells can be cultured into three …
Establishment and characterization of a canine keratinocyte organoid culture system.
Wiener DJ, Basak O, Asra P, Boonekamp KE, Kretzschmar K, Papaspyropoulos A, Clevers H. Wiener DJ, et al. Among authors: Basak O. Vet Dermatol. 2018 Oct;29(5):375-e126. doi: 10.1111/vde.12541. Epub 2018 Jul 2. Vet Dermatol. 2018. PMID: 29963730
METHODS: Cells derived from microdissected IFE and HFs were seeded in Matrigel and keratinocyte organoids were grown and characterized using immunohistochemistry, RT-qPCR and RNA sequencing. RESULTS: Both organoid lines develop into a basal IFE-like cell type. Gene …
METHODS: Cells derived from microdissected IFE and HFs were seeded in Matrigel and keratinocyte organoids were grown and characterize …
Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.
Tetteh PW, Basak O, Farin HF, Wiebrands K, Kretzschmar K, Begthel H, van den Born M, Korving J, de Sauvage F, van Es JH, van Oudenaarden A, Clevers H. Tetteh PW, et al. Among authors: Basak O. Cell Stem Cell. 2016 Feb 4;18(2):203-13. doi: 10.1016/j.stem.2016.01.001. Epub 2016 Jan 28. Cell Stem Cell. 2016. PMID: 26831517 Free article.
Genetic fate-mapping of Alpi(+) cells before or during targeted ablation of Lgr5-expressing stem cells generated numerous long-lived crypt-villus "ribbons," indicative of dedifferentiation of enterocyte precursors into Lgr5(+) stems. By single-cell analysis o …
Genetic fate-mapping of Alpi(+) cells before or during targeted ablation of Lgr5-expressing stem cells generated numerous long …
29 results
Jump to page
Feedback