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Incremental Doses of Nitrate-Rich Beetroot Juice Do Not Modify Cognitive Function and Cerebral Blood Flow in Overweight and Obese Older Adults: A 13-Week Pilot Randomised Clinical Trial.
Babateen AM, Shannon OM, O'Brien GM, Okello E, Smith E, Olgacer D, Koehl C, Fostier W, Wightman E, Kennedy D, Mathers JC, Siervo M. Babateen AM, et al. Nutrients. 2022 Mar 2;14(5):1052. doi: 10.3390/nu14051052. Nutrients. 2022. PMID: 35268027 Free PMC article. Clinical Trial.
This pilot study tested the effects of prolonged consumption of a range of doses of dietary nitrate (NO(3)(-)), provided as beetroot juice, on cognitive function and cerebral blood flow (CBF) in overweight and obese older participants. ...The fi …
This pilot study tested the effects of prolonged consumption of a range of doses of dietary nitrate (NO(3)(-)), provided as beetroot …
Dietary nitrate modulates cerebral blood flow parameters and cognitive performance in humans: A double-blind, placebo-controlled, crossover investigation.
Wightman EL, Haskell-Ramsay CF, Thompson KG, Blackwell JR, Winyard PG, Forster J, Jones AM, Kennedy DO. Wightman EL, et al. Physiol Behav. 2015 Oct 1;149:149-58. doi: 10.1016/j.physbeh.2015.05.035. Epub 2015 May 31. Physiol Behav. 2015. PMID: 26037632 Clinical Trial.
The current study assessed the effects of dietary nitrate on cognitive performance and prefrontal cortex cerebral blood-flow (CBF) parameters in healthy adults. In this randomised, double-blind, placebo-controlled, parallel-groups study, 40 healthy adu …
The current study assessed the effects of dietary nitrate on cognitive performance and prefrontal cortex cerebral blood …
A Randomized, Crossover Study of the Acute Cognitive and Cerebral Blood Flow Effects of Phenolic, Nitrate and Botanical Beverages in Young, Healthy Humans.
Jackson PA, Wightman EL, Veasey R, Forster J, Khan J, Saunders C, Mitchell S, Haskell-Ramsay CF, Kennedy DO. Jackson PA, et al. Nutrients. 2020 Jul 28;12(8):2254. doi: 10.3390/nu12082254. Nutrients. 2020. PMID: 32731478 Free PMC article. Clinical Trial.
OBJECTIVE: The current study investigated the effects of combining extracts of beetroot, ginseng and sage with phenolic-rich apple, blueberry and coffee berry extracts. ...Cognition, mood and CBF parameters were assessed at baseline and then again at 60, 180 and 360 …
OBJECTIVE: The current study investigated the effects of combining extracts of beetroot, ginseng and sage with phenolic-rich apple, b …
Protocol and recruitment results from a 13-week randomized controlled trial comparing the effects of different doses of nitrate-rich beetroot juice on cognition, cerebral blood flow and peripheral vascular function in overweight and obese older people.
Babateen AM, Rubele S, Shannon O, Okello E, Smith E, McMahon N, O'Brien G, Wightman E, Kennedy D, Mathers JC, Siervo M. Babateen AM, et al. Contemp Clin Trials Commun. 2020 Apr 25;18:100571. doi: 10.1016/j.conctc.2020.100571. eCollection 2020 Jun. Contemp Clin Trials Commun. 2020. PMID: 32405570 Free PMC article.
Secondary aims tested dose-dependent changes in cognitive, vascular and pulmonary functions and cerebral blood flow (CBF). METHODS: This was a single blind, four-arm parallel RCT conducted in 60 overweight and obese older participants. ...Measurements …
Secondary aims tested dose-dependent changes in cognitive, vascular and pulmonary functions and cerebral blood flow …
Acute effects of nitrate and breakfast on working memory, cerebral blood flow, arterial stiffness, and psychological factors in adolescents: Study protocol for a randomised crossover trial.
Regan C, Heiland EG, Ekblom Ö, Tarassova O, Kjellenberg K, Larsen FJ, Walltott H, Fernström M, Nyberg G, Ekblom MM, Helgadóttir B. Regan C, et al. PLoS One. 2023 May 19;18(5):e0285581. doi: 10.1371/journal.pone.0285581. eCollection 2023. PLoS One. 2023. PMID: 37205681 Free PMC article.
Therefore, this study will investigate the acute effects of nitrate and breakfast on working memory performance, task-related cerebral blood flow (CBF), arterial stiffness, and psychological outcomes in Swedish adolescents. ...Consequently, results will indic …
Therefore, this study will investigate the acute effects of nitrate and breakfast on working memory performance, task-related cerebral …
Can Beetroot (Beta vulgaris) Support Brain Health? A Perspective Review on Alzheimer's Disease.
Kimble R, Shannon OM. Kimble R, et al. Nutrients. 2025 Dec 3;17(23):3790. doi: 10.3390/nu17233790. Nutrients. 2025. PMID: 41374080 Free PMC article. Review.
Human studies further suggest that nitrate-rich beetroot can improve cerebral blood flow and vascular responsiveness, and that higher intakes of plant-derived nitrate are associated with reduced cognitive decline. ...By integrating vascular, ant …
Human studies further suggest that nitrate-rich beetroot can improve cerebral blood flow and vascular responsive …
Effects of a Dietary Beetroot Juice Treatment on Systemic and Cerebral Haemodynamics- A Pilot Study.
Curry BH, Bond V, Pemminati S, Gorantla VR, Volkova YA, Kadur K, Millis RM. Curry BH, et al. J Clin Diagn Res. 2016 Jul;10(7):CC01-5. doi: 10.7860/JCDR/2016/20049.8113. Epub 2016 Jul 1. J Clin Diagn Res. 2016. PMID: 27630836 Free PMC article.
INTRODUCTION: Beetroot Juice (BJ) contains dietary nitrates that increase the blood Nitric Oxide (NO) level, decrease Blood Pressure (BP), increase athletic performance and improve cognitive functions but the mechanism remains unclear. Ultrasonographic …
INTRODUCTION: Beetroot Juice (BJ) contains dietary nitrates that increase the blood Nitric Oxide (NO) level, decrease Blood …
Performance and Health Benefits of Dietary Nitrate Supplementation in Older Adults: A Systematic Review.
Stanaway L, Rutherfurd-Markwick K, Page R, Ali A. Stanaway L, et al. Nutrients. 2017 Oct 27;9(11):1171. doi: 10.3390/nu9111171. Nutrients. 2017. PMID: 29077028 Free PMC article.
This systematic review examines 12 randomised, crossover, control trials, investigating food-based NO3(-) supplementation in older adults and its potential benefits on physiological and cognitive performances, and CV, cerebrovascular and metabolic health. Four studi …
This systematic review examines 12 randomised, crossover, control trials, investigating food-based NO3(-) supplementation in older adults an …