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Year Number of Results
1975 1
1986 1
1989 1
1992 3
1997 1
1998 1
1999 2
2001 2
2002 1
2003 1
2004 2
2005 4
2006 5
2007 5
2008 6
2009 4
2010 3
2011 2
2012 5
2013 4
2014 4
2015 4
2016 4
2017 4
2018 4
2019 2
2020 0
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Gut-brain and brain-gut axis in Parkinson's disease models: Effects of a uridine and fish oil diet.
Perez-Pardo P, Dodiya HB, Broersen LM, Douna H, van Wijk N, Lopes da Silva S, Garssen J, Keshavarzian A, Kraneveld AD. Perez-Pardo P, et al. Nutr Neurosci. 2018 Jul;21(6):391-402. doi: 10.1080/1028415X.2017.1294555. Epub 2017 Mar 9. Nutr Neurosci. 2018. PMID: 28276272
Recent investigations have focused on the potential role of gastrointestinal (GI) abnormalities in the pathogenesis of Parkinson's disease (PD). ...The dietary intervention may provide benefits in the prevention of motor and non-motor symptoms in PD....
Recent investigations have focused on the potential role of gastrointestinal (GI) abnormalities in the pathogenesis of Parkinson's di …
The Metabolic Map into the Pathomechanism and Treatment of PGM1-CDG.
Radenkovic S, Bird MJ, Emmerzaal TL, Wong SY, Felgueira C, Stiers KM, Sabbagh L, Himmelreich N, Poschet G, Windmolders P, Verheijen J, Witters P, Altassan R, Honzik T, Eminoglu TF, James PM, Edmondson AC, Hertecant J, Kozicz T, Thiel C, Vermeersch P, Cassiman D, Beamer L, Morava E, Ghesquière B. Radenkovic S, et al. Am J Hum Genet. 2019 May 2;104(5):835-846. doi: 10.1016/j.ajhg.2019.03.003. Epub 2019 Apr 11. Am J Hum Genet. 2019. PMID: 30982613 Free PMC article.
Here, we confirm the clinical benefit of galactose supplementation in PGM1-CDG-affected individuals and obtain significant insights into the functional and biochemical regulation of glycosylation. ...
Here, we confirm the clinical benefit of galactose supplementation in PGM1-CDG-affected individuals and obtain significant insights i …
BrdU/EdU dual labeling to determine the cell-cycle dynamics of defined cellular subpopulations.
Harris L, Zalucki O, Piper M. Harris L, et al. J Mol Histol. 2018 Jun;49(3):229-234. doi: 10.1007/s10735-018-9761-8. Epub 2018 Feb 14. J Mol Histol. 2018. PMID: 29445897
Measuring the mean duration of synthesis-phase (T(s)) and of the total cell-cycle (T(c)) within progenitor cell populations can provide important insights into the biology governing these cells. ...For example, in the rodent forebrain, T(s) is selectively lengthened …
Measuring the mean duration of synthesis-phase (T(s)) and of the total cell-cycle (T(c)) within progenitor cell populations can provi …
Systemic regulation of bilirubin homeostasis: Potential benefits of hyperbilirubinemia.
Fujiwara R, Haag M, Schaeffeler E, Nies AT, Zanger UM, Schwab M. Fujiwara R, et al. Hepatology. 2018 Apr;67(4):1609-1619. doi: 10.1002/hep.29599. Epub 2018 Mar 2. Hepatology. 2018. PMID: 29059457 Review.
Accumulation of bilirubin in the brain leads to the onset of irreversible brain damage, termed kernicterus. Breastfeeding is one of the most significant factors that increase the risk of developing kernicterus in infants. Why does this most natural way of feeding in …
Accumulation of bilirubin in the brain leads to the onset of irreversible brain damage, termed kernicterus. Breastfeeding is o …
Souvenaid in the management of mild cognitive impairment: an expert consensus opinion.
Cummings J, Passmore P, McGuinness B, Mok V, Chen C, Engelborghs S, Woodward M, Manzano S, Garcia-Ribas G, Cappa S, Bertolucci P, Chu LW. Cummings J, et al. Alzheimers Res Ther. 2019 Aug 17;11(1):73. doi: 10.1186/s13195-019-0528-6. Alzheimers Res Ther. 2019. PMID: 31421681 Free PMC article.
Although single-agent nutritional supplements have failed to produce cognitive benefits for patients with MCI, a broader nutritional approach warrants consideration. Evidence from randomized controlled trials suggests that Souvenaid should be considered as an option for so …
Although single-agent nutritional supplements have failed to produce cognitive benefits for patients with MCI, a broader nutritional …
Ambient temperature influences the neural benefits of exercise.
Maynard ME, Chung C, Comer A, Nelson K, Tran J, Werries N, Barton EA, Spinetta M, Leasure JL. Maynard ME, et al. Behav Brain Res. 2016 Feb 15;299:27-31. doi: 10.1016/j.bbr.2015.11.017. Epub 2015 Nov 30. Behav Brain Res. 2016. PMID: 26608539
Exercise represents a significant challenge to the brain because it produces heat, but brain temperature does not rise during exercise in the cold. ...Brains were immunohistochemically processed for dividing cells (Ki67+), surviving cells (BrdU+) and new neur …
Exercise represents a significant challenge to the brain because it produces heat, but brain temperature does not rise during …
Effect Size Analyses of Souvenaid in Patients with Alzheimer's Disease.
Cummings J, Scheltens P, McKeith I, Blesa R, Harrison JE, Bertolucci PH, Rockwood K, Wilkinson D, Wijker W, Bennett DA, Shah RC. Cummings J, et al. J Alzheimers Dis. 2017;55(3):1131-1139. doi: 10.3233/JAD-160745. J Alzheimers Dis. 2017. PMID: 27767993 Free PMC article. Clinical Trial.
Effect size was determined by calculating Cohen's d statistic (or Cramér's V method for nominal data), number needed to treat and number needed to harm. ...No effect was shown on cognition in patients with mild-to-moderate AD (S-Connect). The number needed to …
Effect size was determined by calculating Cohen's d statistic (or Cramér's V method for nominal data), number needed to treat …
The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis.
Kee N, Sivalingam S, Boonstra R, Wojtowicz JM. Kee N, et al. J Neurosci Methods. 2002 Mar 30;115(1):97-105. doi: 10.1016/s0165-0270(02)00007-9. J Neurosci Methods. 2002. PMID: 11897369
This was expected, since BrdU can be incorporated into DNA only during the S-phase of the mitotic process, whereas Ki-67 is expressed for its whole duration. ...Thus, Ki-67 is an effective mitotic marker and has most of the benefits of BrdU and none of the costs. Th …
This was expected, since BrdU can be incorporated into DNA only during the S-phase of the mitotic process, whereas Ki-67 is expressed …
Synergistic benefits of erythropoietin and simvastatin after traumatic brain injury.
Chauhan NB, Gatto R. Chauhan NB, et al. Brain Res. 2010 Nov 11;1360:177-92. doi: 10.1016/j.brainres.2010.09.010. Epub 2010 Sep 15. Brain Res. 2010. PMID: 20833152
Simvastatin and recombinant human erythropoietin (rhEpo) are implicated as potential therapeutic candidates for traumatic brain injury (TBI). ...
Simvastatin and recombinant human erythropoietin (rhEpo) are implicated as potential therapeutic candidates for traumatic brain injur …
Differentiation and neurological benefit of the mesenchymal stem cells transplanted into the rat brain following intracerebral hemorrhage.
Zhang H, Huang Z, Xu Y, Zhang S. Zhang H, et al. Neurol Res. 2006 Jan;28(1):104-12. doi: 10.1179/016164106X91960. Neurol Res. 2006. PMID: 16464372
Previous studies indicate that mesenchymal stem cells (MSCs) grafted into the ischemic rat brain can improve neurological function. ...We generated the ICH model by injecting collagenase VII into rat brain. Subsequently, 5-bromo-2-deoxyuridine (BrdU)-labeled mesench …
Previous studies indicate that mesenchymal stem cells (MSCs) grafted into the ischemic rat brain can improve neurological function. . …
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