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1910 1
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1953 1
1954 2
1956 2
1957 5
1958 1
1959 1
1960 1
1965 2
1968 1
1969 5
1970 1
1971 3
1972 4
1973 3
1974 4
1975 7
1976 6
1977 4
1978 2
1979 7
1980 6
1981 6
1982 10
1983 9
1984 10
1985 14
1986 11
1987 13
1988 11
1989 8
1990 13
1991 14
1992 8
1993 11
1994 11
1995 21
1996 20
1997 27
1998 26
1999 25
2000 31
2001 14
2002 13
2003 24
2004 22
2005 33
2006 39
2007 55
2008 52
2009 46
2010 57
2011 67
2012 68
2013 82
2014 78
2015 102
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2017 81
2018 88
2019 84
2020 95
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2023 123
2024 37

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Exposure to di-2-ethylhexyl phthalate and breast neoplasm incidence: A cohort study.
Tang L, Wang Y, Yan W, Zhang Z, Luo S, Wen Q, Wang S, Zhou N, Chen Q, Xu Y. Tang L, et al. Sci Total Environ. 2024 May 20;926:171819. doi: 10.1016/j.scitotenv.2024.171819. Epub 2024 Mar 19. Sci Total Environ. 2024. PMID: 38508268 Free article.
OBJECTIVES: To examine the association between DEHP exposure and incidence of breast malignant neoplasm, carcinoma in situ and benign neoplasm. METHODS: A total of 273,295 women from UK Biobank cohort were followed up for a median of 13.5 years. Disease infor …
OBJECTIVES: To examine the association between DEHP exposure and incidence of breast malignant neoplasm, carcinoma in situ and ben
Development and validation of a model and nomogram for breast cancer diagnosis based on quantitative analysis of serum disease-specific haptoglobin N-glycosylation.
Li L, Xu Y, Lai Z, Li D, Sun Q, Li Z, Zhou Y. Li L, et al. J Transl Med. 2024 Apr 4;22(1):331. doi: 10.1186/s12967-024-05039-4. J Transl Med. 2024. PMID: 38575942 Free PMC article. Clinical Trial.
RESULTS: 95 N-glycopeptides at glycosylation sites N207/N211, N241, and N184 were identified in 235 patients with benign breast diseases and 262 patients with breast cancer. DSHp-beta N-tetrafucosyl and hexafucosyl were significantly increased in br
RESULTS: 95 N-glycopeptides at glycosylation sites N207/N211, N241, and N184 were identified in 235 patients with benign breast
Thymic lipofibroadenoma: A case report.
Kazemi A, Nourizadeh AM, Arjmand G, Haseli S, Askari E. Kazemi A, et al. Radiol Case Rep. 2024 Jan 13;19(4):1340-1343. doi: 10.1016/j.radcr.2023.12.060. eCollection 2024 Apr. Radiol Case Rep. 2024. PMID: 38292789 Free PMC article.
After performing a complete excision, a histologic examination of the excised mass revealed it to be LFA of the thymus, which is extremely rare. The follow-up period was uneventful. LFA is a slow-growing benign tumor and is very similar to fibroadenoma of the breast
After performing a complete excision, a histologic examination of the excised mass revealed it to be LFA of the thymus, which is extremely r …
Is there an association between endometriosis and subsequent breast cancer? A retrospective cohort study from Germany.
Gremke N, Griewing S, Göhring J, Isselhard A, Wagner U, Kostev K, Kalder M. Gremke N, et al. Breast Cancer Res Treat. 2024 Apr;204(2):359-365. doi: 10.1007/s10549-023-07211-8. Epub 2023 Dec 23. Breast Cancer Res Treat. 2024. PMID: 38141056 Free PMC article.
PURPOSE: Given the relatively high incidence of both endometriosis and breast cancer, investigating the potential connection between these gynecological diseases is of substantial clinical significance. ...Non-endometriosis patients were matched 1:1 to patients with …
PURPOSE: Given the relatively high incidence of both endometriosis and breast cancer, investigating the potential connection between …
Temporal changes in mammographic breast density and breast cancer risk among women with benign breast disease.
Mullooly M, Fan S, Pfeiffer RM, Bowles EA, Duggan MA, Falk RT, Richert-Boe K, Glass AG, Kimes TM, Figueroa JD, Rohan TE, Abubakar M, Gierach GL. Mullooly M, et al. Breast Cancer Res. 2024 Mar 26;26(1):52. doi: 10.1186/s13058-024-01764-2. Breast Cancer Res. 2024. PMID: 38532516 Free PMC article.
INTRODUCTION: Benign breast disease (BBD) and high mammographic breast density (MBD) are prevalent and independent risk factors for invasive breast cancer. ...RESULTS: Overall, 64.5% (n = 329) of BBD patients had non-proliferative and 35.5% (n = …
INTRODUCTION: Benign breast disease (BBD) and high mammographic breast density (MBD) are prevalent and independe …
An enhanced and efficient approach for feature selection for chronic human disease prediction: A breast cancer study.
Khanna M, Singh LK, Shrivastava K, Singh R. Khanna M, et al. Heliyon. 2024 Feb 28;10(5):e26799. doi: 10.1016/j.heliyon.2024.e26799. eCollection 2024 Mar 15. Heliyon. 2024. PMID: 38463826 Free PMC article.
These algorithms were previously employed; however, their effectiveness in addressing FS issues in predicting human diseases has not been investigated. The following evaluation focuses on the categorization of benign and malignant tumours using the publicly availabl …
These algorithms were previously employed; however, their effectiveness in addressing FS issues in predicting human diseases has not …
Treatment modalities for granulomatous mastitis, seeking the most appropriate treatment with the least recurrence rate: a systematic review and meta-analysis.
Sarmadian R, Safi F, Sarmadian H, Shokrpour M, Almasi-Hashiani A. Sarmadian R, et al. Eur J Med Res. 2024 Mar 12;29(1):164. doi: 10.1186/s40001-024-01761-3. Eur J Med Res. 2024. PMID: 38475841 Free PMC article.
BACKGROUND: Granulomatous mastitis (GM) is a rare, benign, inflammatory breast disease with an unknown etiology that predominantly affects women of reproductive age. ...CONCLUSION: The optimal treatment strategy for GM depends on the disease's severity …
BACKGROUND: Granulomatous mastitis (GM) is a rare, benign, inflammatory breast disease with an unknown etiology that pr …
The crosstalk between benign thyroid disease and breast cancer: A single center study.
Zheng Y, Tang H, Wu J, Guan D, Mo Q, Zheng Q. Zheng Y, et al. Medicine (Baltimore). 2024 Mar 8;103(10):e37298. doi: 10.1097/MD.0000000000037298. Medicine (Baltimore). 2024. PMID: 38457535 Free PMC article.
This study aims to investigate the relationship between benign thyroid disease and breast cancer. The clinical study includes a total of 600 participants, divided into 2 groups: the control group (N = 300), which consists of individuals from the checkup popul …
This study aims to investigate the relationship between benign thyroid disease and breast cancer. The clinical study in …
Pubertal gynecomastia incidence among 530,000 boys: a cross sectional population based study.
Berger O, Hornik-Lurie T, Talisman R. Berger O, et al. Front Pediatr. 2024 Mar 6;12:1367550. doi: 10.3389/fped.2024.1367550. eCollection 2024. Front Pediatr. 2024. PMID: 38510076 Free PMC article.
BACKGROUND: Adolescent gynecomastia, a benign proliferation of male breast tissue, can lead to psychological issues during adolescence. ...Participants aged 12-15 years were included if diagnosed with gynecomastia (International classification of diseases-9 c …
BACKGROUND: Adolescent gynecomastia, a benign proliferation of male breast tissue, can lead to psychological issues during ado …
Bilateral plasma cell mastitis simulating breast cancer: a case report and literature review.
Ashindoitiang J, Nwagbara V, Ugbem T, Ukam J, Asuquo M. Ashindoitiang J, et al. J Int Med Res. 2024 Mar;52(3):3000605241233167. doi: 10.1177/03000605241233167. J Int Med Res. 2024. PMID: 38483137 Free PMC article. Review.
Plasma cell mastitis (PCM) is a chronic inflammatory disease of the breast. It is a benign entity mainly found in nonpregnant and nonlactating women. ...Early presentation and diagnosis are crucial because PCM, a benign disease, can lead to rema …
Plasma cell mastitis (PCM) is a chronic inflammatory disease of the breast. It is a benign entity mainly found in nonpr …
Kv 11.1 Expression Is Associated With Malignancy of Canine Mammary Gland Tumors.
Lee N, Lee S, Kim W. Lee N, et al. In Vivo. 2024 Mar-Apr;38(2):719-724. doi: 10.21873/invivo.13493. In Vivo. 2024. PMID: 38418114 Free PMC article.
The aim of this study was to identify Kv 11.1 expression in 57 benign and malignant cMGT tissues from dogs and to investigate the correlation of Kv 11.1 expression with the clinicopathological parameters and prognosis of cMGT. ...RESULTS: Immunohistochemical analysis revea …
The aim of this study was to identify Kv 11.1 expression in 57 benign and malignant cMGT tissues from dogs and to investigate the cor …
Male breast abscess: A rare entity.
Alzayyat R, Bokhari D, Almuhanna A, Al-Maghrebi D. Alzayyat R, et al. Radiol Case Rep. 2023 Dec 29;19(3):1122-1127. doi: 10.1016/j.radcr.2023.12.014. eCollection 2024 Mar. Radiol Case Rep. 2023. PMID: 38259713 Free PMC article.
Breast abscess in males is a rare condition, which accounts for 1%-3% of all documented breast diseases. ...Fine needle aspiration and culture were performed again after antibiotics and grossly showed 2-3 cc of pus without any growth in culture. Male breas
Breast abscess in males is a rare condition, which accounts for 1%-3% of all documented breast diseases. ...Fine needle
Mammographically detected breast clustered microcalcifications localized by chest thin-section computed tomography.
Liu X, Bao Y, Sui L, Cao J, Wang Y, Yu C, Qiao G, Cong Y. Liu X, et al. World J Surg Oncol. 2024 Feb 29;22(1):72. doi: 10.1186/s12957-024-03354-0. World J Surg Oncol. 2024. PMID: 38419107 Free PMC article.
Pathological results showed 42 cases were cancer, 23 cases were benign, and 6 cases were atypical hyperplasia. The mean age in the CT + MG group was older than that of the MG group (54.12 vs. 49.27 years; P = 0.014). ...
Pathological results showed 42 cases were cancer, 23 cases were benign, and 6 cases were atypical hyperplasia. The mean age in the CT …
Benign Breast Disease among Patients Visiting the Breast and Endocrine Clinic of a Tertiary Care Centre.
Poudel S, Pokharel S, Khadka S. Poudel S, et al. JNMA J Nepal Med Assoc. 2024 Feb 24;62(270):92-94. doi: 10.31729/jnma.8426. JNMA J Nepal Med Assoc. 2024. PMID: 38409990 Free PMC article.
This study aimed to find the prevalence of benign breast diseases among patients visiting the breast and endocrine clinic of a tertiary care centre. ...KEYWORDS: benign; breast diseases; mastalgia; prevalence....
This study aimed to find the prevalence of benign breast diseases among patients visiting the breast and endocri …
Efficiency Assessment of Breast Clinics for Patients Under 35: A Comparative Analysis of Targeted Models in a University Hospital.
Fagbemi OO, Ojo C, Khan MA, Marla S, Narayanan S, Jafferbhoy S, Soumian S. Fagbemi OO, et al. Cureus. 2024 Feb 18;16(2):e54428. doi: 10.7759/cureus.54428. eCollection 2024 Feb. Cureus. 2024. PMID: 38510890 Free PMC article.
Despite the higher incidence of breast cancer in older age groups, it remains pertinent not to overlook breast cancer occurrence in those aged 35 years and below. ...Targeted breast clinics for individuals 35 years and below offer an effective approach in ter …
Despite the higher incidence of breast cancer in older age groups, it remains pertinent not to overlook breast cancer occurren …
Using a combination of superb microvascular imaging and other auxiliary ultrasound techniques to increase the accuracy of gray-scale ultrasound for breast masses.
Abedi M, Sahebi L, Eslami B, Saberi A, Orouji M, Alipour S, Shahsavarhaghighi S. Abedi M, et al. BMC Cancer. 2024 Feb 16;24(1):224. doi: 10.1186/s12885-024-11981-9. BMC Cancer. 2024. PMID: 38365653 Free PMC article.
BACKGROUND: Breast ultrasound is highly sensitive, but its specificity is not as high for detecting malignant lesions. ...Superb microvascular imaging (SMI) is a newer modality with more accuracy for detecting breast lesions. In this study, our goal was to investiga …
BACKGROUND: Breast ultrasound is highly sensitive, but its specificity is not as high for detecting malignant lesions. ...Superb micr …
Dielectric Characterization of Ex-Vivo Breast Tissues: Differentiation of Tumor Types through Permittivity Measurements.
Fernández-Aranzamendi EG, Castillo-Araníbar PR, San Román Castillo EG, Oller BS, Ventura-Zaa L, Eguiluz-Rodriguez G, González-Posadas V, Segovia-Vargas D. Fernández-Aranzamendi EG, et al. Cancers (Basel). 2024 Feb 15;16(4):793. doi: 10.3390/cancers16040793. Cancers (Basel). 2024. PMID: 38398184 Free PMC article.
Early analysis and diagnosis of breast tumors is essential for either quickly launching a treatment or for seeing the evolution of patients who, for instance, have already undergone chemotherapy treatment. ...These results highlight the effectiveness of these measurements …
Early analysis and diagnosis of breast tumors is essential for either quickly launching a treatment or for seeing the evolution of pa …
Training an automated circulating tumor cell classifier when the true classification is uncertain.
Nanou A, Stoecklein NH, Doerr D, Driemel C, Terstappen LWMM, Coumans FAW. Nanou A, et al. PNAS Nexus. 2024 Feb 9;3(2):pgae048. doi: 10.1093/pnasnexus/pgae048. eCollection 2024 Feb. PNAS Nexus. 2024. PMID: 38371418 Free PMC article.
Refinement was performed using automatic contrast maximization CM-CTC of events detected in cancer and in benign samples (CM-CTC). We used 418 samples from benign diseases, 6,293 from nonmetastatic breast, 2,408 from metastatic breast, and 698 f …
Refinement was performed using automatic contrast maximization CM-CTC of events detected in cancer and in benign samples (CM-CTC). We …
Productivity losses from short-term work absence due to neoplasms in Poland.
Łyszczarz B. Łyszczarz B. Sci Rep. 2024 Feb 8;14(1):3289. doi: 10.1038/s41598-024-53878-4. Sci Rep. 2024. PMID: 38332168 Free PMC article.
Around 60% of the losses were associated with cancers while the remaining part of the burden was due to non-malignant neoplasms. The neoplasms that led to the highest losses were benign neoplasms, breast cancer, colorectum cancer and prostate cancer. ...Investing in …
Around 60% of the losses were associated with cancers while the remaining part of the burden was due to non-malignant neoplasms. The neoplas …
Potential added value of computed tomography radiomics to multimodal prediction models for benign and malignant breast tumors.
Qin J, Qin X, Duan Y, Xie Y, Zhou Y, Zhang C. Qin J, et al. Transl Cancer Res. 2024 Jan 31;13(1):317-329. doi: 10.21037/tcr-23-1042. Epub 2024 Jan 15. Transl Cancer Res. 2024. PMID: 38410225 Free PMC article.
This study examined whether integrating computed tomography (CT) radiomics information based on ultrasound (US) models can improve the efficacy of breast cancer prediction. METHODS: We retrospectively analyzed 420 patients with pathologically confirmed benign or mal …
This study examined whether integrating computed tomography (CT) radiomics information based on ultrasound (US) models can improve the effic …
Application of computer-aided diagnosis to predict malignancy in BI-RADS 3 breast lesions.
He P, Chen W, Bai MY, Li J, Wang QQ, Fan LH, Zheng J, Liu CT, Zhang XR, Yuan XR, Song PJ, Cui LG. He P, et al. Heliyon. 2024 Jan 17;10(2):e24560. doi: 10.1016/j.heliyon.2024.e24560. eCollection 2024 Jan 30. Heliyon. 2024. PMID: 38304808 Free PMC article.
PURPOSE: To evaluate the ability of computer-aided diagnosis (CAD) system (S-Detect) to identify malignancy in ultrasound (US) -detected BI-RADS 3 breast lesions. MATERIALS AND METHODS: 148 patients with 148 breast lesions categorized as BI-RADS 3 were included in t …
PURPOSE: To evaluate the ability of computer-aided diagnosis (CAD) system (S-Detect) to identify malignancy in ultrasound (US) -detected BI- …
Idiopathic Granulomatous Mastitis.
Dilaveri C, Degnim A, Lee C, DeSimone D, Moldoveanu D, Ghosh K. Dilaveri C, et al. Breast J. 2024 Jan 25;2024:6693720. doi: 10.1155/2024/6693720. eCollection 2024. Breast J. 2024. PMID: 38304866 Free PMC article. Review.
Idiopathic granulomatous mastitis (IGM) is a rare, benign inflammatory disorder of the breast that is often underrecognized. ...Patients typically present with a painful mass and symptoms of inflammation, and these features can sometimes mimic breast cancer. …
Idiopathic granulomatous mastitis (IGM) is a rare, benign inflammatory disorder of the breast that is often underrecognized. . …
Expression analysis of lymphocyte subsets and lymphocyte-to-monocyte ratio: reveling immunosuppression and chronic inflammation in breast cancer.
Zhang H, Li Y, Liu G, Chen X. Zhang H, et al. J Cancer Res Clin Oncol. 2024 Jan 23;150(1):28. doi: 10.1007/s00432-023-05508-1. J Cancer Res Clin Oncol. 2024. PMID: 38263363 Free PMC article.
Furthermore, it seeks to examine the correlation between these subsets and LMR with clinicopathological features. METHODS: A total of 100 breast cancer patients were selected as the experimental group, while 55 patients with benign breast diseases were …
Furthermore, it seeks to examine the correlation between these subsets and LMR with clinicopathological features. METHODS: A total of 100 …
Correlation of Histopathology and Radiological Findings Among the Diverse Breast Lesions in a Tertiary Care Centre.
Mohan R, Selvakumar A S, S R, K M, S S, Kathiah R, T R, Rajan Prasaad P, Kumar S D, K S. Mohan R, et al. Cureus. 2024 Jan 11;16(1):e52097. doi: 10.7759/cureus.52097. eCollection 2024 Jan. Cureus. 2024. PMID: 38344545 Free PMC article.
Introduction Breast lumps in any age group are addressed cautiously to exclude the possibility of breast cancer. ...Results A total of 400 cases were reviewed. There were 238 (59.5%) histologically confirmed benign breast lesions and 162 (40.5%) malign …
Introduction Breast lumps in any age group are addressed cautiously to exclude the possibility of breast cancer. ...Results A …
Margin status impact on recurrence of phyllodes tumors in high-risk groups: a retrospective observational study.
Ranjbar A, Zangouri V, Shokripour M. Ranjbar A, et al. BMC Cancer. 2024 Jan 9;24(1):48. doi: 10.1186/s12885-023-11805-2. BMC Cancer. 2024. PMID: 38195454 Free PMC article.
The data were collected from medical records from 2001 to 2020 in the breast clinic of Shahid Motahhari Clinic of Shiraz. Patients were followed up for at least 3 years after the operation to be checked for local recurrence or distant metastasis at regular intervals. ...CO …
The data were collected from medical records from 2001 to 2020 in the breast clinic of Shahid Motahhari Clinic of Shiraz. Patients we …
Multimodal ultrasound imaging for diagnostic differentiation of sclerosing adenosis from invasive ductal carcinoma.
Li W, Zheng Y, Liu H, Tai Z, Zhu H, Li Z, Gu Q, Li Y. Li W, et al. Quant Imaging Med Surg. 2024 Jan 3;14(1):877-887. doi: 10.21037/qims-23-524. Epub 2024 Jan 2. Quant Imaging Med Surg. 2024. PMID: 38223094 Free PMC article.
BACKGROUND: Sclerosing adenosis (SA) is a common proliferative benign lesion without atypia in the breast that may mimic invasive ductal carcinoma (IDC) on medical imaging, leading to it often being misdiagnosed and mistreated. ...METHODS: Multimodal ultrasound imag …
BACKGROUND: Sclerosing adenosis (SA) is a common proliferative benign lesion without atypia in the breast that may mimic invas …
Adenomyoepithelial adenosis mimicking phylloides: A diagnostic dilemma.
Singh J, Singhai A, Babu S, Singh K, Mishra A. Singh J, et al. Indian J Pathol Microbiol. 2024 Jan-Mar;67(1):223-225. doi: 10.4103/ijpm.ijpm_925_22. Indian J Pathol Microbiol. 2024. PMID: 38358228 Free article.
Benign proliferative breast diseases are well recognized in young females. ...Benign proliferative breast diseases are well recognized in young females. ...
Benign proliferative breast diseases are well recognized in young females. ...Benign proliferative breast
Development of a cost-effective compact diode-laser-based photoacoustic sensing instrument for breast tissue diagnosis.
Khan S, Mukhopadhyay S, Vasudevan S, Goel G, Joshi D, Kapoor N, Das S. Khan S, et al. J Biomed Opt. 2024 Jan;29(1):017002. doi: 10.1117/1.JBO.29.1.017002. Epub 2024 Jan 11. J Biomed Opt. 2024. PMID: 38213472 Free PMC article.
RESULTS: The corresponding dominant frequency peak in the PA spectral response (PASR) study was low in the fibrofatty normal breast tissue 0.26 0.03 MHz, compared to the dominant frequency peak of 1.60 0.016 MHz in the fibrocystic disease tissue, which had in …
RESULTS: The corresponding dominant frequency peak in the PA spectral response (PASR) study was low in the fibrofatty normal breast t …
Potential Usefulness a Coronal View using an Automated Breast Ultrasound System in Detecting Breast Lesions.
Suzuki M, Nakayama R, Namba K, Kawami H, Nara M, Nakamura S. Suzuki M, et al. Eur J Breast Health. 2023 Dec 27;20(1):57-63. doi: 10.4274/ejbh.galenos.2023.2023-11-6. eCollection 2024 Jan. Eur J Breast Health. 2023. PMID: 38187110 Free PMC article.
OBJECTIVE: An automated breast ultrasound system (ABUS) combined with screening mammography has increased cancer detection rates; however, supplemental ABUS use has increased recall rates. ...MATERIALS AND METHODS: This retrospective observer study included comprised 114 A …
OBJECTIVE: An automated breast ultrasound system (ABUS) combined with screening mammography has increased cancer detection rates; how …
A New Set of in Silico Tools to Support the Interpretation of ATM Missense Variants Using Graphical Analysis.
Porras LM, Padilla N, Moles-Fernández A, Feliubadaló L, Santamariña-Pena M, Sánchez AT, López-Novo A, Blanco A, de la Hoya M, Molina IJ, Osorio A, Pineda M, Rueda D, Ruiz-Ponte C, Vega A, Lázaro C, Díez O, Gutiérrez-Enríquez S, de la Cruz X. Porras LM, et al. J Mol Diagn. 2024 Jan;26(1):17-28. doi: 10.1016/j.jmoldx.2023.09.009. Epub 2023 Oct 19. J Mol Diagn. 2024. PMID: 37865290 Free article.
Establishing the pathogenic nature of variants in ATM, a gene associated with breast cancer and other hereditary cancers, is crucial for providing patients with adequate care. ...We propose a family of fast and easy-to-use graphical representations in which the impact of a …
Establishing the pathogenic nature of variants in ATM, a gene associated with breast cancer and other hereditary cancers, is crucial …
Evaluating clinical efficacy of hospital-based surveillance with mammography and ultrasonography for breast cancer.
Han HJ, Huang CS, Lu TP, Tseng LM, Chie WC, Huang CC. Han HJ, et al. J Formos Med Assoc. 2024 Jan;123(1):78-87. doi: 10.1016/j.jfma.2023.06.006. Epub 2023 Jul 1. J Formos Med Assoc. 2024. PMID: 37400295 Free article.
Healthy controls underwent breast surveillance and were concurrently free of cancer. More benign diseases rather than cancers were identified from premenopausal women (age 50 years) with sonography alone within one year, as well as older women (age >50) wi …
Healthy controls underwent breast surveillance and were concurrently free of cancer. More benign diseases rather than c …
Galactocele.
Gada PB, Bakhshi G. Gada PB, et al. 2023 Jan 16. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jan 16. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 35201708 Free Books & Documents.
Galactocele, also known as lactocele, or a lacteal cyst, is a rare benign retention cyst of the breast, defined as a milk-filled cyst. ...Although a galactocele can occur anywhere along the milk line extending from the axilla to the groin, it has a predilection to f …
Galactocele, also known as lactocele, or a lacteal cyst, is a rare benign retention cyst of the breast, defined as a milk-fill …
Danazol.
Ashfaq S, Can AS. Ashfaq S, et al. 2023 Mar 11. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Mar 11. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 33232014 Free Books & Documents.
It is also used in other gynecological problems like uterine fibroids and fibrocystic breast disease and various hematological diseases such as in patients with persistent/chronic refractory immune thrombocytopenia (ITP) who failed to respond to cortic …
It is also used in other gynecological problems like uterine fibroids and fibrocystic breast disease and various hemato …
Breast Cyst.
Kowalski A, Okoye E. Kowalski A, et al. 2023 Sep 4. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Sep 4. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 32965867 Free Books & Documents.
They represent the most common cause of breast mass or breast symptoms in general. Breast cysts are part of a larger benign disease process known as fibrocystic disease of the breast. ...Many studies report that in women, th …
They represent the most common cause of breast mass or breast symptoms in general. Breast cysts are part of a larger …
Fibrocystic Breast Disease.
Malherbe K, Khan M, Fatima S. Malherbe K, et al. 2023 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31869073 Free Books & Documents.
Fibrocystic breast disease is the most common benign type of breast disease, diagnosed in millions of women worldwide. Certain hormonal factors underpin the function, evaluation, and treatment of this disease. Benign brea
Fibrocystic breast disease is the most common benign type of breast disease, diagnosed in millions
Breast Examination Techniques.
Henderson JA, Duffee D, Ferguson T. Henderson JA, et al. 2023 Jan 16. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jan 16. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29083747 Free Books & Documents.
A clinical breast exam is a key step in the diagnosis and surveillance of a number of benign and malignant breast diseases. When used as part of a multimodal evaluation, the breast exam provides important information used in both the workup and …
A clinical breast exam is a key step in the diagnosis and surveillance of a number of benign and malignant breast di
Breast Nipple Discharge.
Sajadi-Ernazarova KR, Sugumar K, Adigun R. Sajadi-Ernazarova KR, et al. 2023 Jun 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jun 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 28613688 Free Books & Documents.
Any fluid that leaks from one or both nipples of a non-pregnant and non-breastfeeding breast is referred to as nipple discharge. Nipple discharge is a complex diagnostic challenge for the clinician as it can occur normally or be a manifestation of a wide variety of dise
Any fluid that leaks from one or both nipples of a non-pregnant and non-breastfeeding breast is referred to as nipple discharge. Nipp …
Identification of Risk Factors for Mastalgia and Its Relationship with Benign or Malignant Breast Diseases.
Yigit B, Kilicarslan G, Citgez B. Yigit B, et al. Sisli Etfal Hastan Tip Bul. 2023 Dec 29;57(4):485-494. doi: 10.14744/SEMB.2023.75002. eCollection 2023. Sisli Etfal Hastan Tip Bul. 2023. PMID: 38268653 Free PMC article.
The regular exercise rate in G1 was 18.01%, while it was 25.74% in G2 (p=0.034). The past history of breast cancer rate was significantly higher in G2 than in G1 (p=0.015). ...No significant difference was found concerning the frequency of benign or malignant pathol …
The regular exercise rate in G1 was 18.01%, while it was 25.74% in G2 (p=0.034). The past history of breast cancer rate was significa …
Multi-MicroRNA Analysis Can Improve the Diagnostic Performance of Mammography in Determining Breast Cancer Risk.
Song JE, Jang JY, Kang KN, Jung JS, Kim CW, Kim AS. Song JE, et al. Breast J. 2023 Dec 27;2023:9117047. doi: 10.1155/2023/9117047. eCollection 2023. Breast J. 2023. PMID: 38178922 Free PMC article.
The objective of this study was to determine whether multi-microRNA analysis using a combination of four microRNA biomarkers (miR-1246, 202, 21, and 219B) could improve the diagnostic performance of mammography in determining breast cancer risk by age group (under 50 vs. o …
The objective of this study was to determine whether multi-microRNA analysis using a combination of four microRNA biomarkers (miR-1246, 202, …
Risk analysis of breast cancer and breast fibrocystic change in female primary Sjogren's syndrome patients.
Chen HY, Chung JY, Lin SC. Chen HY, et al. Medicine (Baltimore). 2023 Dec 22;102(51):e36769. doi: 10.1097/MD.0000000000036769. Medicine (Baltimore). 2023. PMID: 38134080 Free PMC article.
Since mammary tissue shares the glandular structure, Sjogren's syndrome may also target mammary tissue to cause breast diseases. We therefore determined whether primary Sjogren's syndrome (pSS) is associated with the increased risk of breast cancer (BC) and …
Since mammary tissue shares the glandular structure, Sjogren's syndrome may also target mammary tissue to cause breast diseases
Growth of a Nipple Adenoma After Estrogen Replacement Therapy.
Skaribas EE, Tschen J. Skaribas EE, et al. Cureus. 2023 Dec 20;15(12):e50843. doi: 10.7759/cureus.50843. eCollection 2023 Dec. Cureus. 2023. PMID: 38249210 Free PMC article.
A 4 mm punch biopsy and subsequent immunohistochemistry stain revealed the proliferation of ductal structures consistent with a papillary adenoma and tumor cells expressing estrogen receptors (ER) and progesterone receptors (PR). Despite their benign nature, nipple adenoma …
A 4 mm punch biopsy and subsequent immunohistochemistry stain revealed the proliferation of ductal structures consistent with a papillary ad …
A hematological parameter-based model for distinguishing non-puerperal mastitis from invasive ductal carcinoma.
Wang Z, Hua L, Liu X, Chen X, Xue G. Wang Z, et al. Front Oncol. 2023 Dec 13;13:1295656. doi: 10.3389/fonc.2023.1295656. eCollection 2023. Front Oncol. 2023. PMID: 38152369 Free PMC article.
PURPOSE: Non-puerperal mastitis (NPM) accounts for approximately 4-5% of all benign breast lesions. Ultrasound is the preferred method for screening breast diseases; however, similarities in imaging results can make it challenging to distinguish NPM fr …
PURPOSE: Non-puerperal mastitis (NPM) accounts for approximately 4-5% of all benign breast lesions. Ultrasound is the preferre …
Comparative Evaluation of Contrast-Enhanced Spectral Mammography and Digital Breast Tomosynthesis for Diagnosing and Treating Breast Cancer.
Yang D, Gong F. Yang D, et al. Med Sci Monit. 2023 Dec 13;29:e941880. doi: 10.12659/MSM.941880. Med Sci Monit. 2023. PMID: 38087777 Free PMC article.
MATERIAL AND METHODS We retrospectively analyzed data on 125 lesions of 115 patients with breast diseases in Lanzhou First People's Hospital from January 2020 to June 2022. ...CONCLUSIONS The diagnostic efficacy of CESM was significantly better than DBT in premenopa …
MATERIAL AND METHODS We retrospectively analyzed data on 125 lesions of 115 patients with breast diseases in Lanzhou First Peo …
Drug Responses in Plexiform Neurofibroma Type I (PNF1) Cell Lines Using High-Throughput Data and Combined Effectiveness and Potency.
Zamora PO, Altay G, Santamaria U, Dwarshuis N, Donthi H, Moon CI, Bakalar D, Zamora M. Zamora PO, et al. Cancers (Basel). 2023 Dec 12;15(24):5811. doi: 10.3390/cancers15245811. Cancers (Basel). 2023. PMID: 38136356 Free PMC article.
Background: Neurofibromatosis type 1 (NF1) is a genetic disorder characterized by heterozygous germline NF1 gene mutations that predispose patients to developing plexiform neurofibromas, which are benign but often disfiguring tumors of the peripheral nerve sheath induced b …
Background: Neurofibromatosis type 1 (NF1) is a genetic disorder characterized by heterozygous germline NF1 gene mutations that predispose p …
Contouring variation affects estimates of normal tissue complication probability for breast fibrosis after radiotherapy.
Jaikuna T, Osorio EV, Azria D, Chang-Claude J, De Santis MC, Gutiérrez-Enríquez S, van Herk M, Hoskin P, Lambrecht M, Lingard Z, Seibold P, Seoane A, Sperk E, Symonds RP, Talbot CJ, Rancati T, Rattay T, Reyes V, Rosenstein BS, de Ruysscher D, Vega A, Veldeman L, Webb A, West CML, Aznar MC. Jaikuna T, et al. Breast. 2023 Dec;72:103578. doi: 10.1016/j.breast.2023.103578. Epub 2023 Sep 11. Breast. 2023. PMID: 37713940 Free PMC article.
BACKGROUND: Normal tissue complication probability (NTCP) models can be useful to estimate the risk of fibrosis after breast-conserving surgery (BCS) and radiotherapy (RT) to the breast. ...CONCLUSION: Contour variations can lead to significantly different NTCP esti …
BACKGROUND: Normal tissue complication probability (NTCP) models can be useful to estimate the risk of fibrosis after breast-conservi …
Assessment of prevalence and factors affecting Mastalgia among early reproductive-aged women in Bangladesh: a cross-sectional survey.
Siddique AB, Nath SD, Mubarak M, Akter A, Mehrin S, Hkatun MJ, Liza AP, Islam MS, Amin MZ, Ferdous MZ. Siddique AB, et al. BMC Public Health. 2023 Nov 17;23(1):2269. doi: 10.1186/s12889-023-17173-7. BMC Public Health. 2023. PMID: 37978504 Free PMC article.
BACKGROUND: Mastalgia, or breast pain, is a prevalent and distressing condition experienced by women, impacting their daily lives and causing complications. It is common among women of reproductive age, with associations found with premenstrual syndrome, fibrocystic
BACKGROUND: Mastalgia, or breast pain, is a prevalent and distressing condition experienced by women, impacting their daily lives and …
Enhancing histopathological image classification of invasive ductal carcinoma using hybrid harmonization techniques.
Abdallah N, Marion JM, Tauber C, Carlier T, Hatt M, Chauvet P. Abdallah N, et al. Sci Rep. 2023 Nov 16;13(1):20014. doi: 10.1038/s41598-023-46239-0. Sci Rep. 2023. PMID: 37973797 Free PMC article.
We assess the proposed pipeline's performance on two public breast cancer databases, BreaKHIS and IDCDB, utilizing recall, precision, and accuracy metrics. ...Our findings reveal that harmonizing variabilities between patches from different batches directly impacts the lea …
We assess the proposed pipeline's performance on two public breast cancer databases, BreaKHIS and IDCDB, utilizing recall, precision, …
Fatty acid profiles and Delta9 desaturase (stearoyl-CoA desaturase; SCD 1) expression in adipose tissue surrounding benign and malignant breast tumors.
Sefidabi R, Alizadeh A, Alipour S, Omranipour R, Shahhoseini M, Izadi A, Vesali S, Moini A. Sefidabi R, et al. Heliyon. 2023 Oct 6;9(11):e20658. doi: 10.1016/j.heliyon.2023.e20658. eCollection 2023 Nov. Heliyon. 2023. PMID: 37885725 Free PMC article.
Understanding the role of adipose tissue (AT), as the main component of the breast tumor microenvironment (TME) in the development of cancer, is crucial for the early detection of breast cancer (BC). This study compared the FA profiles, desaturase index (DI), and st …
Understanding the role of adipose tissue (AT), as the main component of the breast tumor microenvironment (TME) in the development of …
Fibrocystic breast disease with pleomorphic calcifications and segmental distribution: A case report.
JiueLan K, Sekine C, Kurozumi S, Matsuoka R, Komuta M, Shiomi T, Horiguchi J. JiueLan K, et al. Radiol Case Rep. 2023 Aug 25;18(11):3828-3830. doi: 10.1016/j.radcr.2023.08.010. eCollection 2023 Nov. Radiol Case Rep. 2023. PMID: 37670913 Free PMC article.
Fibrocystic breast disease is the most common benign condition and is important for differentiating breast cancer. ...Although fibrocystic breast disease does not require treatment, appropriate follow-up is necessary after a
Fibrocystic breast disease is the most common benign condition and is important for differentiating breast
Rapid Segmentation and Diagnosis of Breast Tumor Ultrasound Images at the Sonographer Level Using Deep Learning.
Yang L, Zhang B, Ren F, Gu J, Gao J, Wu J, Li D, Jia H, Li G, Zong J, Zhang J, Yang X, Zhang X, Du B, Wang X, Li N. Yang L, et al. Bioengineering (Basel). 2023 Oct 19;10(10):1220. doi: 10.3390/bioengineering10101220. Bioengineering (Basel). 2023. PMID: 37892950 Free PMC article.
BACKGROUND: Breast cancer is one of the most common malignant tumors in women. A noninvasive ultrasound examination can identify mammary-gland-related diseases and is well tolerated by dense breast, making it a preferred method for breast cancer screen …
BACKGROUND: Breast cancer is one of the most common malignant tumors in women. A noninvasive ultrasound examination can identify mamm …
Association between breast diseases and symptomatic uterine fibroids by using South Korean National Health Insurance database.
Yuk JS, Yang SW, Yoon SH, Kim MH, Seo YS, Lee Y, Joo Y, Kim J, Yoon SY, Cho H, Yang K, Gwak G. Yuk JS, et al. Sci Rep. 2023 Oct 5;13(1):16772. doi: 10.1038/s41598-023-43443-w. Sci Rep. 2023. PMID: 37798304 Free PMC article.
Both the uterus and breasts have sex hormone dependence, yet there are few studies on the association between breast disease and uterine fibroids (UFs). The purpose of this study was to investigate the incidence of benign breast disease (BBD), c …
Both the uterus and breasts have sex hormone dependence, yet there are few studies on the association between breast disease a …
Pseudoangiomatous stromal hyperplasia: A clinical perspective and a brief review.
Patel G, Bipte S, Narurkar S. Patel G, et al. J Cancer Res Ther. 2023 Oct 1;19(7):1714-1720. doi: 10.4103/jcrt.jcrt_127_22. Epub 2023 Jan 3. J Cancer Res Ther. 2023. PMID: 38376269 Free article. Review.
Pseudoangiomatous stromal hyperplasia (PASH) is a benign entity of the breast and typically found incidentally or as a palpable mass. ...It is associated with a good prognosis with no increased risk to develop breast cancer. Hence, the operating surgeon and p …
Pseudoangiomatous stromal hyperplasia (PASH) is a benign entity of the breast and typically found incidentally or as a palpabl …
Immunohistochemical study of the expressed cluster differentiation markers proteins type 20 and 56 in breast tissues from a group of Iraqi patients with breast cancers.
Zeiny SMH, Mohammed Ali SH. Zeiny SMH, et al. Asian Pac J Cancer Prev. 2023 Oct 1;24(10):3621-3628. doi: 10.31557/APJCP.2023.24.10.3621. Asian Pac J Cancer Prev. 2023. PMID: 37898871 Free PMC article.
Statistical significant differences (P<0.05) between both groups of malignant and benign breast tumors and the control group were found. However, between breast malignant and benign tumor groups, no significant difference was found ( p >0.05). De …
Statistical significant differences (P<0.05) between both groups of malignant and benign breast tumors and the control grou …
Clinicopathological profile of mastalgia in females: incidence, types, and pathological correlations. a cross-Sectional study.
Ali AA, Faraj FH. Ali AA, et al. Ann Med Surg (Lond). 2023 Aug 17;85(10):4764-4772. doi: 10.1097/MS9.0000000000001159. eCollection 2023 Oct. Ann Med Surg (Lond). 2023. PMID: 37811083 Free PMC article.
Non-cyclical diseases are mainly benign rather than malignant. Solid masses (fibroadenomas), cysts, infections, abscesses, trauma, and nipple discharge (hormones) are rare diseases associated with breast cancer. ...Non-cyclical mastalgia was subdivided …
Non-cyclical diseases are mainly benign rather than malignant. Solid masses (fibroadenomas), cysts, infections, abscesses, tra …
Paraneoplastic autoimmune Laminin-332 syndrome (PALS): Anti-Laminin-332 mucous membrane pemphigoid as a prototype.
Ahmed AR, Kalesinskas M, Kooper-Johnson S. Ahmed AR, et al. Autoimmun Rev. 2023 Oct;22(10):103444. doi: 10.1016/j.autrev.2023.103444. Epub 2023 Sep 5. Autoimmun Rev. 2023. PMID: 37673192 Free article. Review.
Recently, autoantibodies to Laminin-332 have been described in several autoimmune diseases. Many of these autoimmune diseases have a high incidence of malignancy. ...EVIDENCE REVIEW: A literature search was conducted to identify autoimmune and inflammatory diseas
Recently, autoantibodies to Laminin-332 have been described in several autoimmune diseases. Many of these autoimmune diseases
Adenosquamous proliferation in radial sclerosing lesions: Histologic spectrum and key features in systematic review of 247 lesions.
Bachert SE, Cornea V, Bocklage T. Bachert SE, et al. Breast. 2023 Oct;71:99-105. doi: 10.1016/j.breast.2023.08.002. Epub 2023 Aug 7. Breast. 2023. PMID: 37566996 Free PMC article.
Adenosquamous proliferation (ASP) is known to occur in the central nidus of radial sclerosing lesions (RSL) of the breast. However, their significance is debated and remains largely unknown. ...
Adenosquamous proliferation (ASP) is known to occur in the central nidus of radial sclerosing lesions (RSL) of the breast. However, t …
Method Comparison and Clinical Performance of Breast Cancer Tumor Markers on Novel Multiplex Immunoassay and Automatized LOCI Technology Platforms.
Schröder L, Mallmann MR, Domroese CM, Wefers N, Dolscheid-Pommerich R, Stoffel-Wagner B, Trulson I, Vahldiek K, Klawonn F, Holdenrieder S. Schröder L, et al. Diagnostics (Basel). 2023 Sep 30;13(19):3101. doi: 10.3390/diagnostics13193101. Diagnostics (Basel). 2023. PMID: 37835844 Free PMC article.
To investigate the method dependency and clinical significance of breast cancer protein tumor markers, CEA, CA 15-3, CA 125, CA 19-9 and AFP were measured in a total of 154 biobanked samples from 77 patients with breast cancer, 10 with DCIS, 31 with benign
To investigate the method dependency and clinical significance of breast cancer protein tumor markers, CEA, CA 15-3, CA 125, CA 19-9 …
Clinicopathological Parameters Predicting Malignancy in Phyllodes Tumor of the Breast.
Hashmi AA, Mallick BA, Rashid K, Zafar S, Zia S, Malik UA, Sapna F, Anjali F, Vishal F, Irfan M. Hashmi AA, et al. Cureus. 2023 Sep 28;15(9):e46168. doi: 10.7759/cureus.46168. eCollection 2023 Sep. Cureus. 2023. PMID: 37908929 Free PMC article.
Introduction Phyllodes tumor (PT) is an uncommon fibroepithelial neoplasm of the breast. It is a biphasic tumor with stromal and epithelial components, with a tendency to recur. Because of its wide range of disease manifestations, it has been subclassified into thre …
Introduction Phyllodes tumor (PT) is an uncommon fibroepithelial neoplasm of the breast. It is a biphasic tumor with stromal and epit …
Is Insulin Receptor Substrate4 (IRS4) a Platform Involved in the Activation of Several Oncogenes?
Guijarro LG, Justo Bermejo FJ, Boaru DL, De Castro-Martinez P, De Leon-Oliva D, Fraile-Martínez O, Garcia-Montero C, Alvarez-Mon M, Toledo-Lobo MDV, Ortega MA. Guijarro LG, et al. Cancers (Basel). 2023 Sep 20;15(18):4651. doi: 10.3390/cancers15184651. Cancers (Basel). 2023. PMID: 37760618 Free PMC article. Review.
We used the name of the protein that it encodes "(IRS-4 or IRS4)", or the combination of these terms with the word "(cancer)" or "(human)", for searches. Terms related to specific tumor pathologies ("breast", "ovary", "colon", "lung", "lymphoma", etc.) were also used. Desp …
We used the name of the protein that it encodes "(IRS-4 or IRS4)", or the combination of these terms with the word "(cancer)" or "(human)", …
Changing the Surgical Approach to Breast Diseases During the COVID-19 Pandemic Period.
Gur HU, Degerli MS. Gur HU, et al. Cureus. 2023 Sep 20;15(9):e45653. doi: 10.7759/cureus.45653. eCollection 2023 Sep. Cureus. 2023. PMID: 37745739 Free PMC article.
Background Postponing elective surgeries during the COVID-19 pandemic has also affected the approach to both malignant and benign breast diseases. This paper aims to share how the COVID-19 pandemic affects our approach to breast cancer, benign
Background Postponing elective surgeries during the COVID-19 pandemic has also affected the approach to both malignant and benign
Perioperative nursing care speed up recover of a male patient after bilateral endoscopic mastectomy: a case report.
Wang LP, Salzberg CA, Benson JR, Rocco N, Liang SS. Wang LP, et al. AME Case Rep. 2023 Sep 18;7:48. doi: 10.21037/acr-23-101. eCollection 2023. AME Case Rep. 2023. PMID: 37942036 Free PMC article.
BACKGROUND: Gynecomastia (GYN) is mainly caused by the benign proliferation of mammary glands and adipose tissue. Currently, up to 38% of adult males have GYN. GYN can be caused by systemic diseases, obesity, endocrine disorders (such as liver cirrhosis, which impai …
BACKGROUND: Gynecomastia (GYN) is mainly caused by the benign proliferation of mammary glands and adipose tissue. Currently, up to 38 …
Tumoral pseudoangiomatous stromal hyperplasia (PASH) of the male breast: A systematic analysis.
Salati SA, Sulaiman Alsulaim L, Elmuttalut MA, Alfehaid M, Ahmad Alsuwaydani S. Salati SA, et al. Pol Przegl Chir. 2023 Sep 6;96(0):78-83. doi: 10.5604/01.3001.0053.8610. Pol Przegl Chir. 2023. PMID: 38348993 Free article.
</br> <b><br>Conclusions:</b> Tumoral PASH is a benign myofibroblastic proliferation disorder rarely reported in males. This condition should be considered a differential diagnosis of breast or axillary lumps, …
</br> <b><br>Conclusions:</b> Tumoral PASH is a benign myofibroblastic prolif …
POST-HOC EXPLAINABILITY OF BI-RADS DESCRIPTORS IN A MULTI-TASK FRAMEWORK FOR BREAST CANCER DETECTION AND SEGMENTATION.
Karimzadeh M, Vakanski A, Xian M, Zhang B. Karimzadeh M, et al. IEEE Int Workshop Mach Learn Signal Process. 2023 Sep;2023:10.1109/mlsp55844.2023.10286006. doi: 10.1109/mlsp55844.2023.10286006. Epub 2023 Oct 23. IEEE Int Workshop Mach Learn Signal Process. 2023. PMID: 38572141 Free PMC article.
Despite recent medical advancements, breast cancer remains one of the most prevalent and deadly diseases among women. ...Thirdly, the proposed approach outputs quantified contributions of each BI-RADS descriptor toward predicting the benign or malignant class …
Despite recent medical advancements, breast cancer remains one of the most prevalent and deadly diseases among women. ...Third …
Clinicopathological pattern of breast lesions in children and adolescents.
Nwafor CC, Umeh KU, Etuk EB, Eziagu UB, Kudamnya IJ, Ekwo E. Nwafor CC, et al. Afr Health Sci. 2023 Sep;23(3):228-235. doi: 10.4314/ahs.v23i3.28. Afr Health Sci. 2023. PMID: 38357104 Free PMC article.
BACKGROUND: Breast lesions are not common in children and adolescents. The aim of this study is to retrospectively survey the clinicopathological pattern of breast lesions in children and adolescents in our setting. ...The mean size of the lumps was 6.2cm 3.9. Fibro …
BACKGROUND: Breast lesions are not common in children and adolescents. The aim of this study is to retrospectively survey the clinico …
Clinicopathological profile of breast cancer from Chhattisgarh India: A single-center hospital-based study.
Srivastava NK, Singh S, Mohanty D, Hussain N. Srivastava NK, et al. J Family Med Prim Care. 2023 Sep;12(9):1923-1930. doi: 10.4103/jfmpc.jfmpc_2315_22. Epub 2023 Sep 30. J Family Med Prim Care. 2023. PMID: 38024932 Free PMC article.
The mean age for breast cancer was 39 3.028 years (ranged 31-50 years). Twenty patients had locally advanced breast carcinoma. ...None breast cancer patients have previous histology-proven benign breast disease. ...
The mean age for breast cancer was 39 3.028 years (ranged 31-50 years). Twenty patients had locally advanced breast carcinoma. …
The value of multimodal magnetic resonance imaging in breast cancer and its correlation with pathological features and prognosis.
Luo Q, Yang L, Zhou X. Luo Q, et al. Eur Rev Med Pharmacol Sci. 2023 Sep;27(18):8397-8403. doi: 10.26355/eurrev_202309_33762. Eur Rev Med Pharmacol Sci. 2023. PMID: 37782156 Free article.
OBJECTIVE: This study aimed to explore the diagnostic value of multimodal magnetic resonance imaging (MRI) in breast cancer (BC) and its correlation with pathological features of the disease. PATIENTS AND METHODS: Clinical data of 85 BC patients (malignant group) an …
OBJECTIVE: This study aimed to explore the diagnostic value of multimodal magnetic resonance imaging (MRI) in breast cancer (BC) and …
Immunohistochemical Detection of the Expressed BRCA1 and BRCA2 Proteins in Microenvironment of Malignant Breast Cancerous Tissues Infected with Human Mammary Tumor Virus.
Mohammed Ali SH, Abid Mohammed KI, Ali WM, Al-Fakhar SA, Al-Alwany SHM, Mousa JM. Mohammed Ali SH, et al. Asian Pac J Cancer Prev. 2023 Sep 1;24(9):3261-3267. doi: 10.31557/APJCP.2023.24.9.3261. Asian Pac J Cancer Prev. 2023. PMID: 37774080 Free PMC article.
RESULTS: There were 12 out of 40 (30%) benign breast tumorous tissues and 14 out of 40 (35%) BC tissues, while healthy control breast tissues were 10% (2 out of 20 tissues). ...CONCLUSION: HMTV might contribute to the development of subsets of benign a …
RESULTS: There were 12 out of 40 (30%) benign breast tumorous tissues and 14 out of 40 (35%) BC tissues, while healthy control …
Hepatic adenoma in a 7-year-old girl: a case report and literature review.
Gao Y, Zhou J, Xie YC, Qiu LJ, Duan L, A ZX, Wu HF, Lv MX. Gao Y, et al. BMC Pediatr. 2023 Aug 24;23(1):420. doi: 10.1186/s12887-023-04209-5. BMC Pediatr. 2023. PMID: 37620840 Free PMC article. Review.
BACKGROUND: Hepatocellular adenomas (HCAs) are rare benign tumors of the liver that occur predominantly in women taking oral contraceptives. ...CASE PRESENTATION: A 7-year-old girl was presented to our hospital with bilateral breast enlargement for 2 months, polydip …
BACKGROUND: Hepatocellular adenomas (HCAs) are rare benign tumors of the liver that occur predominantly in women taking oral contrace …
The "Trunk sign": A novel X-ray sign in galactography of patients with nipple discharge suggesting malignancy.
Wu T, Zhang K, Wang Y, Ma R. Wu T, et al. Medicine (Baltimore). 2023 Aug 11;102(32):e34589. doi: 10.1097/MD.0000000000034589. Medicine (Baltimore). 2023. PMID: 37565883 Free PMC article.
Baseline characteristics were obtained from their electronic records including age, menstruation status, physical examination, galactography, cytology, and pathology. There were 110 cases of benign disease, 12 cases of high-risk disease, and 39 cases of malig …
Baseline characteristics were obtained from their electronic records including age, menstruation status, physical examination, galactography …
Granulomatous Mastitis Occurring during Pregnancy: A Case Report.
Yoshino R, Yoshida N, Ito A, Ujiie N, Nakatsubo M, Hayashi M, Kitada M. Yoshino R, et al. Medicina (Kaunas). 2023 Aug 3;59(8):1418. doi: 10.3390/medicina59081418. Medicina (Kaunas). 2023. PMID: 37629708 Free PMC article.
Background and Objectives: Granulomatous mastitis is a benign disease with a clinical presentation similar to that of breast cancer, and is most commonly observed in women of childbearing age. ...The occurrence of this disease during pregnancy has rare …
Background and Objectives: Granulomatous mastitis is a benign disease with a clinical presentation similar to that of breas
Low presence of papillomavirus and its lack of correlation with clinicopathological factors in breast cancer: a case control study.
Makvandi M, Rashno M, Faghihloo E, Bagheri S, Hesam S, Mirzaei H, Ramezani A. Makvandi M, et al. Iran J Microbiol. 2023 Aug;15(4):585-593. doi: 10.18502/ijm.v15i4.13513. Iran J Microbiol. 2023. PMID: 38045712 Free PMC article.
BACKGROUND AND OBJECTIVES: Breast cancer is currently the most commonly diagnosed neoplasm in women worldwide. ...The aim of this study was to investigate the presence of the HPV viral genome in benign and malignant breast tissue samples and its clinicopathol …
BACKGROUND AND OBJECTIVES: Breast cancer is currently the most commonly diagnosed neoplasm in women worldwide. ...The aim of this stu …
Epidemiology Trend of Urogenital System Disorders of Hospitalized Patients in an Eastern Chinese City from 2017 to 2019.
Wu W, Zou J, Luo S, Lin H. Wu W, et al. Arch Esp Urol. 2023 Aug;76(6):389-396. doi: 10.56434/j.arch.esp.urol.20237606.47. Arch Esp Urol. 2023. PMID: 37681329 Free article.
The highest prevalence of these diseases was in the 40- to 64-year-old age group (47.37%), followed by the 18- to 39-year-old age group (23.94%). Over the 3 years, the five most common diseases in hospitalized male patients were male reproductive organ disorders, ur …
The highest prevalence of these diseases was in the 40- to 64-year-old age group (47.37%), followed by the 18- to 39-year-old age gro …
Plasma metabolomic signatures of breast cancer.
Xu Y, Zhao B, Xu Z, Li X, Sun Q. Xu Y, et al. Front Med (Lausanne). 2023 Jul 31;10:1148542. doi: 10.3389/fmed.2023.1148542. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37588002 Free PMC article.
In the present study, a wide range of targeted metabolomics profiling was conducted to investigate the plasma signatures of breast cancer. METHODS: A total of 86 patients with benign breast abnormalities (L group) and 143 patients with breast cancer (E …
In the present study, a wide range of targeted metabolomics profiling was conducted to investigate the plasma signatures of breast ca …
Human Cytomegalovirus in breast milk is associated with milk composition, the infant gut microbiome, and infant growth.
Johnson KE, Heisel T, Fields DA, Isganaitis E, Jacobs KM, Knights D, Lock EF, Rudolph MC, Gale CA, Schleiss MR, Albert FW, Demerath EW, Blekhman R. Johnson KE, et al. bioRxiv [Preprint]. 2023 Jul 19:2023.07.19.549370. doi: 10.1101/2023.07.19.549370. bioRxiv. 2023. PMID: 37503212 Free PMC article. Preprint.
Human cytomegalovirus (CMV) is a highly prevalent herpesvirus that is often transmitted to the neonate via breast milk. Postnatal CMV transmission can have negative health consequences for preterm and immunocompromised infants, but any effects on healthy term infants are t …
Human cytomegalovirus (CMV) is a highly prevalent herpesvirus that is often transmitted to the neonate via breast milk. Postnatal CMV …
Evolutionary Origin of Human PALB2 Germline Pathogenic Variants.
Chian JS, Li J, Wang SM. Chian JS, et al. Int J Mol Sci. 2023 Jul 12;24(14):11343. doi: 10.3390/ijms241411343. Int J Mol Sci. 2023. PMID: 37511102 Free PMC article.
Germline pathogenic variation in PALB2 disrupts DNA damage repair and increases the risk of Fanconi Anemia, breast cancer, and ovarian cancer. Determination of the evolutionary origin of human PALB2 variants will promote a deeper understanding of the biological basis of PA …
Germline pathogenic variation in PALB2 disrupts DNA damage repair and increases the risk of Fanconi Anemia, breast cancer, and ovaria …
CXCL12 and CXCR4 as Potential Early Biomarkers for Luminal A and Luminal B Subtypes of Breast Cancer.
Motyka J, Gacuta E, Kicman A, Kulesza M, Malinowski P, Ławicki S. Motyka J, et al. Cancer Manag Res. 2023 Jul 4;15:573-589. doi: 10.2147/CMAR.S416382. eCollection 2023. Cancer Manag Res. 2023. PMID: 37426394 Free PMC article.
PURPOSE: Breast cancer is the most common type of malignancy in women. Factors that increase the risk of occurrence include chronic inflammation, with chemokines as its mediators. ...PATIENTS AND METHODS: The study included 100 patients with early breast cancer of l …
PURPOSE: Breast cancer is the most common type of malignancy in women. Factors that increase the risk of occurrence include chronic i …
Value of negatively correlated miR-205-5p/HMGB3 and miR-96-5p/FOXO1 on the diagnosis of breast cancer and benign breast diseases.
Li J, Peng S, Zou X, Geng X, Wang T, Zhu W, Xia T. Li J, et al. Cancer Pathog Ther. 2023 May 12;1(3):159-167. doi: 10.1016/j.cpt.2023.04.002. eCollection 2023 Jul. Cancer Pathog Ther. 2023. PMID: 38327836 Free PMC article.
We used real-time quantitative reverse transcription polymerase chain reaction to verify BC and benign disease samples, and logistic regression analysis was used to establish a diagnostic model based on miRNAs and target mRNAs. ...CONCLUSIONS: A diagnostic model inc …
We used real-time quantitative reverse transcription polymerase chain reaction to verify BC and benign disease samples, and lo …
A systematic review of Pilomatrix carcinoma arising from the previous scar site of Pilomatrixoma.
Panda SK, Sahoo PK, Agarwala SK, Houghton TT, Sankar KV, Mohanty P. Panda SK, et al. J Cancer Res Ther. 2023 Jul-Sep;19(5):1098-1102. doi: 10.4103/jcrt.jcrt_720_21. J Cancer Res Ther. 2023. PMID: 37787269 Free article. Review.
Since then till date to the best of our knowledge only around 125 cases were reported in literature, of which only 11 cases were reported to arise from histologically proven areas of previous pilomatrixoma which is the benign variant. One such case is being reported here a …
Since then till date to the best of our knowledge only around 125 cases were reported in literature, of which only 11 cases were reported to …
Obesity, obesity-related metabolic conditions, and risk of thyroid cancer in women: results from a prospective cohort study (Sister Study).
Pasqual E, O'Brien K, Rinaldi S, Sandler DP, Kitahara CM. Pasqual E, et al. Lancet Reg Health Am. 2023 Jun 14;23:100537. doi: 10.1016/j.lana.2023.100537. eCollection 2023 Jul. Lancet Reg Health Am. 2023. PMID: 37346380 Free PMC article.
METHODS: From the Sister Study, a cohort of sisters of women with breast cancer, we included 47,739 women who were cancer-free at baseline (2003-2009). ...Cox proportional hazards regression models were adjusted for age (time scale), race/ethnicity, smoking, baseline histo …
METHODS: From the Sister Study, a cohort of sisters of women with breast cancer, we included 47,739 women who were cancer-free at bas …
Cancer status in the Occupied Palestinian Territories: types; incidence; mortality; sex, age, and geography distribution; and possible causes.
Salem HS. Salem HS. J Cancer Res Clin Oncol. 2023 Jul;149(8):5139-5163. doi: 10.1007/s00432-022-04430-2. Epub 2022 Nov 9. J Cancer Res Clin Oncol. 2023. PMID: 36350411 Free PMC article.
Cancer is a disease in which some cells of the body grow uncontrollably and occasionally spread to other parts of the body. ...In addition to other types of cancer in the OPT, its main types are lung (highest in males), breast (highest in females), colorectal (highe …
Cancer is a disease in which some cells of the body grow uncontrollably and occasionally spread to other parts of the body. ...In add …
Development and validation of a prediction model for the diagnosis of breast cancer based on clinical and ultrasonic features.
He X, Lu Y, Li J. He X, et al. Gland Surg. 2023 Jun 30;12(6):736-748. doi: 10.21037/gs-22-663. Epub 2023 Jun 5. Gland Surg. 2023. PMID: 37441019 Free PMC article.
BACKGROUND: The aim of this study was to develop a simple and effective prediction model for calculating the probability of breast cancer by selecting clinical and sonographic features associated with breast cancer. ...RESULTS: One hundred and seventy-nine malignant …
BACKGROUND: The aim of this study was to develop a simple and effective prediction model for calculating the probability of breast ca …
An exploration of the correlations between seven psychiatric disorders and the risks of breast cancer, breast benign tumors and breast inflammatory diseases: Mendelian randomization analyses.
Ren F, Shang Q, Zhao S, Yang C, Feng K, Liu J, Kang X, Zhang R, Wang X, Wang X. Ren F, et al. Front Psychiatry. 2023 Jun 28;14:1179562. doi: 10.3389/fpsyt.2023.1179562. eCollection 2023. Front Psychiatry. 2023. PMID: 37448488 Free PMC article.
BACKGROUND: Previous observational studies have showed that certain psychiatric disorders may be linked to breast cancer risk, there is, however, little understanding of relationships between mental disorders and a variety of breast diseases. This study aims …
BACKGROUND: Previous observational studies have showed that certain psychiatric disorders may be linked to breast cancer risk, there …
Breast Cancer Diagnosis Based on IoT and Deep Transfer Learning Enabled by Fog Computing.
Pati A, Parhi M, Pattanayak BK, Singh D, Singh V, Kadry S, Nam Y, Kang BG. Pati A, et al. Diagnostics (Basel). 2023 Jun 27;13(13):2191. doi: 10.3390/diagnostics13132191. Diagnostics (Basel). 2023. PMID: 37443585 Free PMC article.
Across all countries, both developing and developed, women face the greatest risk of breast cancer. Patients who have their breast cancer diagnosed and staged early have a better chance of receiving treatment before the disease spreads. ...The Internet of Thi …
Across all countries, both developing and developed, women face the greatest risk of breast cancer. Patients who have their breast
Anomaly Detection of Breast Cancer Using Deep Learning.
Alloqmani A, Abushark YB, Khan AI. Alloqmani A, et al. Arab J Sci Eng. 2023 Jun 12:1-26. doi: 10.1007/s13369-023-07945-z. Online ahead of print. Arab J Sci Eng. 2023. PMID: 37361464 Free PMC article.
Cancer is one of the deadliest diseases facing humanity, one of the which is breast cancer, and it can be considered one of the primary causes of death for most women. ...This article proposes an efficient and accurate deep learning-based anomaly detection framework …
Cancer is one of the deadliest diseases facing humanity, one of the which is breast cancer, and it can be considered one of th …
Potential Diagnostic Value of Salivary Tumor Markers in Breast, Lung and Ovarian Cancer: A Preliminary Study.
Bel'skaya LV, Sarf EA, Loginova AI, Vyushkov DM, Choi ED. Bel'skaya LV, et al. Curr Issues Mol Biol. 2023 Jun 10;45(6):5084-5098. doi: 10.3390/cimb45060323. Curr Issues Mol Biol. 2023. PMID: 37367072 Free PMC article.
The aim of the study was to determine the content of tumor markers for breast, lung and ovarian cancer in saliva, as well as for benign diseases of the corresponding organs and in the control group, and to evaluate their diagnostic significance. ...The concen …
The aim of the study was to determine the content of tumor markers for breast, lung and ovarian cancer in saliva, as well as for b
Comparison between cone-beam breast-CT and full-field digital mammography for microcalcification detection depending on breast density.
Wienbeck S, Andrijevska V, Kück F, Perske C, Unterberg-Buchwald C, Fischer U, Lotz J, Kunze M. Wienbeck S, et al. Medicine (Baltimore). 2023 Jun 2;102(22):e33900. doi: 10.1097/MD.0000000000033900. Medicine (Baltimore). 2023. PMID: 37266644 Free PMC article.
The purpose of this study was to evaluate the impact of breast density on the diagnostic performance of cone-beam breast-CT (CBBCT) in comparison to full-field digital mammography (FFDM) for the detection of microcalcifications. ...Thirty-two breasts (35.5%) were gr …
The purpose of this study was to evaluate the impact of breast density on the diagnostic performance of cone-beam breast-CT (C …
Benign and malignant breast diseases during pregnancy and lactation: a diagnostic challenge.
Rahim A, Hafeez M, Sattar A, Farooqui WA. Rahim A, et al. J Pak Med Assoc. 2023 Jun;73(6):1192-1196. doi: 10.47391/JPMA.6111. J Pak Med Assoc. 2023. PMID: 37427613 Free article.
METHODS: The descriptive, observational study was conducted at the Dow Institute of Radiology, DUHS, Karachi from December 2020 to August 2021, and comprised of pregnant and lactating women with clinically palpable breast lumps and/or painful breast. The margins, or …
METHODS: The descriptive, observational study was conducted at the Dow Institute of Radiology, DUHS, Karachi from December 2020 to August 20 …
Effect of the COVID-19 pandemic on surgery for indeterminate thyroid nodules (THYCOVID): a retrospective, international, multicentre, cross-sectional study.
Medas F, Dobrinja C, Al-Suhaimi EA, Altmeier J, Anajar S, Arikan AE, Azaryan I, Bains L, Basili G, Bolukbasi H, Bononi M, Borumandi F, Bozan MB, Brenta G, Brunaud L, Brunner M, Buemi A, Canu GL, Cappellacci F, Cartwright SB, Castells Fusté I, Cavalheiro B, Cavallaro G, Chala A, Chan SYB, Chaplin J, Cheema MS, Chiapponi C, Chiofalo MG, Chrysos E, D'Amore A, de Cillia M, De Crea C, de Manzini N, de Matos LL, De Pasquale L, Del Rio P, Demarchi MS, Dhiwakar M, Donatini G, Dora JM, D'Orazi V, Doulatram Gamgaram VK, Eismontas V, Kabiri EH, El Malki HO, Elzahaby I, Enciu O, Eskander A, Feroci F, Figueroa-Bohorquez D, Filis D, François G, Frías-Fernández P, Gamboa-Dominguez A, Genc V, Giordano D, Gómez-Pedraza A, Graceffa G, Griffin J, Guerreiro SC, Gupta K, Gupta KK, Gurrado A, Hajiioannou J, Hakala T, Harahap WA, Hargitai L, Hartl D, Hellmann A, Hlozek J, Hoang VT, Iacobone M, Innaro N, Ioannidis O, Jang JHI, Xavier-Junior JC, Jovanovic M, Kaderli RM, Kakamad F, Kaliszewski K, Karamanliev M, Katoh H, Košec A, Kovacevic B, Kowalski LP, Králik R, Yadav SK, Kumorová A, Lampridis S, Lasithiotakis K, Leclere JC, Leong EKF, Leow MK, Lim JY, Lino-Silva LS, Liu SYW, Llorach NP, Lombardi CP, Lóp… See abstract for full author list ➔ Medas F, et al. Lancet Diabetes Endocrinol. 2023 Jun;11(6):402-413. doi: 10.1016/S2213-8587(23)00094-3. Epub 2023 Apr 28. Lancet Diabetes Endocrinol. 2023. PMID: 37127041 Free PMC article.
FINDINGS: Data from 157 centres (n=49 countries) on 87 467 patients who underwent surgery for benign and malignant thyroid disease were collected, of whom 22 974 patients (18 052 [78.6%] female patients and 4922 [21.4%] male patients) received surgery for indetermin …
FINDINGS: Data from 157 centres (n=49 countries) on 87 467 patients who underwent surgery for benign and malignant thyroid disease
Current clinical practice in the management of phyllodes tumors of the breast: an international cross-sectional study among surgeons and oncologists.
Sars C, Sackey H, Frisell J, Dickman PW, Karlsson F, Kindts I, Marta GN, Freitas-Junior R, Tvedskov TF, Kassem L, Ali AS, Ihalainen H, Neron M, Kontos M, Kaidar-Person O, Meattini I, Francken AB, van Duijnhoven F, Moberg IO, Marinko T, Kollar A, Ahmed M, Remoundos D, Banks J, Jagsi R, Dossett LA, Lindqvist EK. Sars C, et al. Breast Cancer Res Treat. 2023 Jun;199(2):293-304. doi: 10.1007/s10549-023-06896-1. Epub 2023 Mar 6. Breast Cancer Res Treat. 2023. PMID: 36879102 Free PMC article.
PURPOSE: Phyllodes tumors of the breast are rare fibroepithelial lesions that are classified as benign, borderline or malignant. ...The majority of respondents were experienced and worked in a university hospital. Most agreed to recommend a tumor-free excision margi …
PURPOSE: Phyllodes tumors of the breast are rare fibroepithelial lesions that are classified as benign, borderline or malignan …
Improving the Quantitative Analysis of Breast Microcalcifications: A Multiscale Approach.
Marasinou C, Li B, Paige J, Omigbodun A, Nakhaei N, Hoyt A, Hsu W. Marasinou C, et al. J Digit Imaging. 2023 Jun;36(3):1016-1028. doi: 10.1007/s10278-022-00751-3. Epub 2023 Feb 23. J Digit Imaging. 2023. PMID: 36820930 Free PMC article.
We modeled the extracted features using gradient tree boosting to classify each case as benign or malignant. Compared to state-of-the-art comparison methods, our approach achieved superior mean intersection over the union (0.670 0.121 per image versus 0.524 0.034 per image …
We modeled the extracted features using gradient tree boosting to classify each case as benign or malignant. Compared to state-of-the …
Optimising clinical care through CDH1-specific germline variant curation: improvement of clinical assertions and updated curation guidelines.
Luo X, Maciaszek JL, Thompson BA, Leong HS, Dixon K, Sousa S, Anderson M, Roberts ME, Lee K, Spurdle AB, Mensenkamp AR, Brannan T, Pardo C, Zhang L, Pesaran T, Wei S, Fasaye GA, Kesserwan C, Shirts BH, Davis JL, Oliveira C, Plon SE, Schrader KA, Karam R; ClinGen CDH1 Variant Curation Expert Panel. Luo X, et al. J Med Genet. 2023 Jun;60(6):568-575. doi: 10.1136/jmg-2022-108807. Epub 2022 Dec 7. J Med Genet. 2023. PMID: 36600593 Free PMC article.
BACKGROUND: Germline pathogenic variants in CDH1 are associated with increased risk of diffuse gastric cancer and lobular breast cancer. Risk reduction strategies include consideration of prophylactic surgery, thereby making accurate interpretation of germline CDH1 variant …
BACKGROUND: Germline pathogenic variants in CDH1 are associated with increased risk of diffuse gastric cancer and lobular breast canc …
Case report: Abrikossoff's tumor of the facial skin.
Ardeleanu V, Jecan RC, Moroianu M, Teodoreanu RN, Tebeica T, Moroianu LA, Bujoreanu FC, Nwabudike LC, Tatu AL. Ardeleanu V, et al. Front Med (Lausanne). 2023 May 31;10:1149735. doi: 10.3389/fmed.2023.1149735. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37324160 Free PMC article.
The most common location is in the oral cavity, followed by the skin, but they can also be found in the breast, digestive tract, tracheobronchial tree, or central nervous system. ...This manuscript presents the case of a 12-year-old girl with a benign GCT, located i …
The most common location is in the oral cavity, followed by the skin, but they can also be found in the breast, digestive tract, trac …
DOG-1 as a Myoepithelial Marker in Discriminating Invasive Breast Carcinomas From Non-Invasive Breast Lesions.
Perumandal S, Ponnaboina DM, Moula MC, Rajan YR. Perumandal S, et al. Cureus. 2023 May 29;15(5):e39676. doi: 10.7759/cureus.39676. eCollection 2023 May. Cureus. 2023. PMID: 37398743 Free PMC article.

P63 expression was strongly positive in benign breast diseases and strongly negative in malignant diseases (p < 0.0001). Conclusion DOG1 seems to be similar to p63 as a myoepithelial cell marker both in normal breast tissue and in benign

P63 expression was strongly positive in benign breast diseases and strongly negative in malignant diseases (p &l …
Radiomics Analysis of Breast Lesions in Combination with Coronal Plane of ABVS and Strain Elastography.
Ma Q, Shen C, Gao Y, Duan Y, Li W, Lu G, Qin X, Zhang C, Wang J. Ma Q, et al. Breast Cancer (Dove Med Press). 2023 May 26;15:381-390. doi: 10.2147/BCTT.S410356. eCollection 2023. Breast Cancer (Dove Med Press). 2023. PMID: 37260586 Free PMC article.
BACKGROUND: Breast cancer is the most common tumor globally. Automated Breast Volume Scanner (ABVS) and strain elastography (SE) can provide more useful breast information. The use of radiomics combined with ABVS and SE images to predict breast cancer …
BACKGROUND: Breast cancer is the most common tumor globally. Automated Breast Volume Scanner (ABVS) and strain elastography (S …
Autophagy regulates sex steroid hormone synthesis through lysosomal degradation of lipid droplets in human ovary and testis.
Esmaeilian Y, Hela F, Bildik G, İltumur E, Yusufoglu S, Yildiz CS, Yakin K, Kordan Y, Oktem O. Esmaeilian Y, et al. Cell Death Dis. 2023 May 26;14(5):342. doi: 10.1038/s41419-023-05864-3. Cell Death Dis. 2023. PMID: 37236920 Free PMC article.
Our data, together with the findings of the previous works, may have significant clinical implications by opening a new avenue in understanding and treatment of a wide range of diseases, from reproductive disorders to sex steroid-producing neoplasms, sex steroid-dependent …
Our data, together with the findings of the previous works, may have significant clinical implications by opening a new avenue in understand …
Prevalence, Impact, and Diagnostic Challenges of Benign Breast Disease: A Narrative Review.
Fraker JL, Clune CG, Sahni SK, Yaganti A, Vegunta S. Fraker JL, et al. Int J Womens Health. 2023 May 18;15:765-778. doi: 10.2147/IJWH.S351095. eCollection 2023. Int J Womens Health. 2023. PMID: 37223067 Free PMC article. Review.
Benign breast diseases, which are commonly seen in clinical practice, have various clinical presentations and implications, as well as management strategies. ...Also included in this review are the most recent data and guideline-based recommendations for the
Benign breast diseases, which are commonly seen in clinical practice, have various clinical presentations and implicati
Benign breast disease with malignant imaging features: a case report.
Zhong Y, Cheng Y, Chen L, Yin Y. Zhong Y, et al. J Med Case Rep. 2023 May 16;17(1):197. doi: 10.1186/s13256-023-03931-z. J Med Case Rep. 2023. PMID: 37189170 Free PMC article.
BACKGROUND: Diabetic mastopathy is a rare breast condition that occurs in women with poorly controlled diabetes and is characterized by hardening of the breast tissue. ...Her past medical history was otherwise unremarkable. Physical examination of the breast
BACKGROUND: Diabetic mastopathy is a rare breast condition that occurs in women with poorly controlled diabetes and is characterized …
ANO10 is a potential prognostic biomarker and correlates with immune infiltration in breast cancer.
Ning R, Pan S, Xiao D, Zheng Y, Zhang J. Ning R, et al. Am J Cancer Res. 2023 May 15;13(5):1845-1862. eCollection 2023. Am J Cancer Res. 2023. PMID: 37293146 Free PMC article.
Compared to benign breast lesions, the protein level of ANO10 was lower in malignant breast tumors. ...Altogether, ANO10 is a potential biomarker that can effectively predict the prognosis of breast cancer. Our findings highlight the promising prognost …
Compared to benign breast lesions, the protein level of ANO10 was lower in malignant breast tumors. ...Altogether, ANO1 …
The Ratio of Monocyte to Apolipoprotein A1 is an Independent Predictor of Breast Cancer: A Retrospective Study.
Lin Z, Luo C, Yuan Y. Lin Z, et al. Cancer Manag Res. 2023 May 15;15:423-432. doi: 10.2147/CMAR.S402770. eCollection 2023. Cancer Manag Res. 2023. PMID: 37214188 Free PMC article.
METHODS: The hematological test results of 394 patients with breast diseases, including 276 cases of BC, 118 cases of benign breast disease (BBD), and 219 healthy volunteers (HV), were retrospectively collected. ...CONCLUSION: MAR is a new indic …
METHODS: The hematological test results of 394 patients with breast diseases, including 276 cases of BC, 118 cases of benig
VinDr-Mammo: A large-scale benchmark dataset for computer-aided diagnosis in full-field digital mammography.
Nguyen HT, Nguyen HQ, Pham HH, Lam K, Le LT, Dao M, Vu V. Nguyen HT, et al. Sci Data. 2023 May 12;10(1):277. doi: 10.1038/s41597-023-02100-7. Sci Data. 2023. PMID: 37173336 Free PMC article.
Mammography, or breast X-ray imaging, is the most widely used imaging modality to detect cancer and other breast diseases. ...The dataset consists of 5,000 mammography exams, each of which has four standard views and is double read with disagreement (if any) …
Mammography, or breast X-ray imaging, is the most widely used imaging modality to detect cancer and other breast diseases
Supervised breast cancer prediction using integrated dimensionality reduction convolutional neural network.
Xu H, Shao X, Hui S, Jin L. Xu H, et al. PLoS One. 2023 May 5;18(5):e0282350. doi: 10.1371/journal.pone.0282350. eCollection 2023. PLoS One. 2023. PMID: 37146014 Free PMC article.
Early detection of breast cancer will promote treatment. A technology that determines whether a tumor is benign desirable. This article introduces a new method in which deep learning is used to classify breast cancer. METHODS: A new computer-aided detection ( …
Early detection of breast cancer will promote treatment. A technology that determines whether a tumor is benign desirable. Thi …
Lymphocytic interstitial pneumonia presenting with a ground glass nodule: A case report and literature review.
Liu Q, Chen Z, Deng P, Wang J, Zhang S, Tang L, Yang Y, Lang B. Liu Q, et al. Medicine (Baltimore). 2023 May 5;102(18):e33613. doi: 10.1097/MD.0000000000033613. Medicine (Baltimore). 2023. PMID: 37144997 Free PMC article. Review.
RATIONALE: Lymphocytic interstitial pneumonia (LIP) is a rare benign lymphoproliferative disorder, often associated with autoimmune diseases. ...
RATIONALE: Lymphocytic interstitial pneumonia (LIP) is a rare benign lymphoproliferative disorder, often associated with autoimmune …
Targeting the formation of estrogens for treatment of hormone dependent diseases-current status.
Rižner TL, Romano A. Rižner TL, et al. Front Pharmacol. 2023 Apr 28;14:1155558. doi: 10.3389/fphar.2023.1155558. eCollection 2023. Front Pharmacol. 2023. PMID: 37188267 Free PMC article. Review.
Local formation and action of estrogens have crucial roles in hormone dependent cancers and benign diseases like endometriosis. Drugs that are currently used for the treatment of these diseases act at the receptor and at the pre-receptor levels, targeting the …
Local formation and action of estrogens have crucial roles in hormone dependent cancers and benign diseases like endometriosis …
Restoration of the Lost Human Beta Defensin (hBD-1) in Cancer as a Strategy to Improve the Efficacy of Chemotherapy.
Pandurangi RS, Sekar TV, Paulmurugan R. Pandurangi RS, et al. bioRxiv [Preprint]. 2023 Apr 5:2023.04.03.535411. doi: 10.1101/2023.04.03.535411. bioRxiv. 2023. PMID: 37066380 Free PMC article. Preprint.
Both innate and adaptive immunity are the important components of the human defense system against various diseases including cancer. Human Beta Defensin (hBD-1) is one such immunomodulatory peptide which is lost at high frequencies in malignant cancers, while high levels …
Both innate and adaptive immunity are the important components of the human defense system against various diseases including cancer. …
PTEN hamartoma tumour syndrome: case report based on data from the Iranian hereditary colorectal cancer registry and literature review.
Rahmatinejad Z, Goshayeshi L, Bergquist R, Goshayeshi L, Golabpour A, Hoseini B. Rahmatinejad Z, et al. Diagn Pathol. 2023 Apr 4;18(1):43. doi: 10.1186/s13000-023-01331-x. Diagn Pathol. 2023. PMID: 37016356 Free PMC article. Review.
Whole-exome sequencing led to a PHTS diagnosis, even though the patient displayed no clinical or skin symptoms of the condition. Further screenings identified early-stage breast cancer and benign thyroid nodules through mammography and thyroid ultrasound. ...The lit …
Whole-exome sequencing led to a PHTS diagnosis, even though the patient displayed no clinical or skin symptoms of the condition. Further scr …
Unilateral hyperpigmented lesion of the breast.
Chaima K, Mariem A, Khadija S, Rim K, Emna B, Tahya B, Hamida T. Chaima K, et al. Clin Case Rep. 2023 Apr 2;11(4):e7132. doi: 10.1002/ccr3.7132. eCollection 2023 Apr. Clin Case Rep. 2023. PMID: 37020668 Free PMC article.
Muco-cutaneous melanosis is a benign entity with no progression. Although, dermoscopic features may help to differentiate melanosis from malignant pigmented diseases, histopathology remains crucial for the confirming of melanosis of the nipple and areola. ...
Muco-cutaneous melanosis is a benign entity with no progression. Although, dermoscopic features may help to differentiate melanosis f …
Prognostic Significance Of FOXP3+ Tumour-Infiltrating Tregs In Egyptian Breast Cancer Patients.
Abdelkader MM, Saied EM, ElShourbagy SH, El-Anwer NM. Abdelkader MM, et al. J Pak Med Assoc. 2023 Apr;73(Suppl 4)(4):S146-S150. doi: 10.47391/JPMA.EGY-S4-30. J Pak Med Assoc. 2023. PMID: 37482848 Free article.
OBJECTIVES: To evaluate the prognostic importance of tumour-infiltrating forkhead box P3 protein + regulatory T cells in breast cancer patients. METHOD: The case-control study was conducted from January 2020 to March 2021 at the Kafrelsheikh University Hospital, Egypt, and …
OBJECTIVES: To evaluate the prognostic importance of tumour-infiltrating forkhead box P3 protein + regulatory T cells in breast cance …
Clinicohistopathological study of benign breast lesions in surgically excised specimens in a tertiary care hospital.
Boral S, Jagtap SV. Boral S, et al. J Cancer Res Ther. 2023 Apr;19(Supplement):S116-S120. doi: 10.4103/jcrt.JCRT_688_20. J Cancer Res Ther. 2023. PMID: 37147991 Free article.
BACKGROUND: Distinguishing benign breast diseases (BBDs) from malignant breast diseases is a worrisome entity and should also have knowledge of the pattern of occurrence of the disorders in their geographical location. ...Of the 153 cases, 94 ca …
BACKGROUND: Distinguishing benign breast diseases (BBDs) from malignant breast diseases is a worrisome en …
Evaluation of Benign Breast Diseases With or Without Atypical Epithelial Hyperplasia Accompanying Radial Scars.
Turkyilmaz Z, Sarisik E, Ozkurt E, Tukenmez M, Emiroglu S, Emiroglu B, Onder S, Yilmaz R, Muslumanoglu M, Igci A, Ozmen V, Cabioglu N. Turkyilmaz Z, et al. Eur J Breast Health. 2023 Apr 1;19(2):166-171. doi: 10.4274/ejbh.galenos.2023.2022-10-4. eCollection 2023 Apr. Eur J Breast Health. 2023. PMID: 37025577 Free PMC article.
OBJECTIVE: A radial scar (RS) is a benign breast lesion (BBL) that has an obscure etiology. RS is easily confused with breast carcinoma and therefore correct identification radiologically and pathologically is important. ...Atypical epithelial hyperplasia (AE …
OBJECTIVE: A radial scar (RS) is a benign breast lesion (BBL) that has an obscure etiology. RS is easily confused with brea
The largest and heaviest giant juvenile fibroadenoma of the breast in the Chinese population: A case report.
Zhang Y, Huang J, Zhou L, Leng Y. Zhang Y, et al. Medicine (Baltimore). 2023 Mar 31;102(13):e33422. doi: 10.1097/MD.0000000000033422. Medicine (Baltimore). 2023. PMID: 37000060 Free PMC article.
RATIONALE: Fibroadenoma is the most common benign tumor of the breast, but giant juvenile fibroadenoma exceeding 20 cm is much rare. ...DIAGNOSIS AND INTERVENTIONS: An 18-year-old adolescent girl with a 2-year history of a large left breast mass with progress …
RATIONALE: Fibroadenoma is the most common benign tumor of the breast, but giant juvenile fibroadenoma exceeding 20 cm is much …
Plasma Levels of Metalloproteinase 3 (MMP-3) and Metalloproteinase 7 (MMP-7) as New Candidates for Tumor Biomarkers in Diagnostic of Breast Cancer Patients.
Ławicki P, Malinowski P, Motyka J, Ławicki M, Kicman A, Kulesza M, Gacuta E, Guszczyn T, Januszkiewicz M, Zbucka-Krętowska M, Ławicki S. Ławicki P, et al. J Clin Med. 2023 Mar 30;12(7):2618. doi: 10.3390/jcm12072618. J Clin Med. 2023. PMID: 37048701 Free PMC article.
The role of matrix metalloproteinase-3 (MMP-3) and (MMP-7) in the pathogenesis of breast cancer (BC) has been demonstrated, suggesting that they may be considered as potential markers of this condition. The aim of this study was to assess plasma concentrations and diagnost …
The role of matrix metalloproteinase-3 (MMP-3) and (MMP-7) in the pathogenesis of breast cancer (BC) has been demonstrated, suggestin …
Exploration of utility of combined optical photothermal infrared and Raman imaging for investigating the chemical composition of microcalcifications in breast cancer.
Bouzy P, Lyburn ID, Pinder SE, Scott R, Mansfield J, Moger J, Greenwood C, Bouybayoune I, Cornford E, Rogers K, Stone N. Bouzy P, et al. Anal Methods. 2023 Mar 30;15(13):1620-1630. doi: 10.1039/d2ay01197b. Anal Methods. 2023. PMID: 36880909 Free PMC article.
They are evaluated by their radiological and histological characteristics but it is challenging to find a link between their morphology, their composition and the nature of a specific type of breast lesion. Whilst there are some mammographic features that are either typica …
They are evaluated by their radiological and histological characteristics but it is challenging to find a link between their morphology, the …
Trans-axillary single port insufflation technique-assisted endoscopic surgery for breast diseases: Clinic experience, cosmetic outcome and oncologic result.
Wang X, Wan X, Li L, Liu X, Meng R, Sun X, Xiao C. Wang X, et al. Front Oncol. 2023 Mar 29;13:1157545. doi: 10.3389/fonc.2023.1157545. eCollection 2023. Front Oncol. 2023. PMID: 37064139 Free PMC article.
RESULTS: A total of 115 cases were included, of which 33 patients with benign disease underwent mass resection, 68 patients with malignant tumors underwent mastectomy. 10 patients had a special type of breast lesion. ...All patients were very satisfied with t …
RESULTS: A total of 115 cases were included, of which 33 patients with benign disease underwent mass resection, 68 patients wi …
Review of Breast Abscess Cases at a Tertiary Hospital in Addis Ababa, Ethiopia.
Suga Y, Kuehn T, W/Ammanuel G, Knfe G, Teklewold B. Suga Y, et al. Int J Womens Health. 2023 Mar 24;15:433-442. doi: 10.2147/IJWH.S391686. eCollection 2023. Int J Womens Health. 2023. PMID: 36999001 Free PMC article.
The majority are benign, but worrisome etiologies such as inflammatory cancer and concomitant immune-compromising diseases should be addressed when a non-lactating patient presents with a breast abscess. ...RESULTS: Two hundred and nine patients were included …
The majority are benign, but worrisome etiologies such as inflammatory cancer and concomitant immune-compromising diseases sho …
Antioxidants in Traditional Mexican Medicine and Their Applications as Antitumor Treatments.
Soto KM, Pérez Bueno JJ, Mendoza López ML, Apátiga-Castro M, López-Romero JM, Mendoza S, Manzano-Ramírez A. Soto KM, et al. Pharmaceuticals (Basel). 2023 Mar 23;16(4):482. doi: 10.3390/ph16040482. Pharmaceuticals (Basel). 2023. PMID: 37111239 Free PMC article. Review.
Traditional medicine in Latin America and mainly in Mexico represents an essential alternative for treating different diseases. The use of plants as medicine is the product of a rich cultural tradition of the indigenous peoples, in which a great variety of species are used …
Traditional medicine in Latin America and mainly in Mexico represents an essential alternative for treating different diseases. The u …
Radiological Society of North America (RSNA) 3D Printing Special Interest Group (SIG) clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: breast conditions.
Arribas EM, Kelil T, Santiago L, Ali A, Chadalavada SC, Chepelev L, Ghodadra A, Ionita CN, Lee J, Ravi P, Ryan JR, Sheikh AM, Rybicki FJ, Ballard DH; RSNA Special Interest 3D Printing Breast Conditions Voting Group. Arribas EM, et al. 3D Print Med. 2023 Mar 23;9(1):8. doi: 10.1186/s41205-023-00171-1. 3D Print Med. 2023. PMID: 36952139 Free PMC article.
The use of medical 3D printing has expanded dramatically for breast diseases. A writing group composed of the Radiological Society of North America (RSNA) Special Interest Group on 3D Printing (SIG) provides updated appropriateness criteria for breast 3D prin …
The use of medical 3D printing has expanded dramatically for breast diseases. A writing group composed of the Radiological Soc …
Investigating the Link between Early Life and Breast Anomalies.
Christopoulos P, Matsas A, Eleftheriades M, Kotsira G, Eleftheriades A, Vlahos NF. Christopoulos P, et al. Children (Basel). 2023 Mar 21;10(3):601. doi: 10.3390/children10030601. Children (Basel). 2023. PMID: 36980159 Free PMC article. Review.
Several factors during childhood and adolescence are thought to be associated with the development of proliferative benign breast diseases and breast cancer in adulthood. In order to identify them, the authors conducted an extensive review of the liter …
Several factors during childhood and adolescence are thought to be associated with the development of proliferative benign breast
An Online Mammography Database with Biopsy Confirmed Types.
Cai H, Wang J, Dan T, Li J, Fan Z, Yi W, Cui C, Jiang X, Li L. Cai H, et al. Sci Data. 2023 Mar 7;10(1):123. doi: 10.1038/s41597-023-02025-1. Sci Data. 2023. PMID: 36882402 Free PMC article.
Breast carcinoma is the second largest cancer in the world among women. ...Mammography, a noninvasive imaging tool with low cost, is widely used to diagnose breast disease at an early stage due to its high sensitivity. Although some public mammography dataset
Breast carcinoma is the second largest cancer in the world among women. ...Mammography, a noninvasive imaging tool with low cost, is
Australian Genomics: Outcomes of a 5-year national program to accelerate the integration of genomics in healthcare.
Stark Z, Boughtwood T, Haas M, Braithwaite J, Gaff CL, Goranitis I, Spurdle AB, Hansen DP, Hofmann O, Laing N, Metcalfe S, Newson AJ, Scott HS, Thorne N, Ward RL, Dinger ME, Best S, Long JC, Grimmond SM, Pearson J, Waddell N, Barnett CP, Cook M, Field M, Fielding D, Fox SB, Gecz J, Jaffe A, Leventer RJ, Lockhart PJ, Lunke S, Mallett AJ, McGaughran J, Mileshkin L, Nones K, Roscioli T, Scheffer IE, Semsarian C, Simons C, Thomas DM, Thorburn DR, Tothill R, White D, Dunwoodie S, Simpson PT, Phillips P, Brion MJ, Finlay K, Quinn MC, Mattiske T, Tudini E, Boggs K, Murray S, Wells K, Cannings J, Sinclair AH, Christodoulou J, North KN. Stark Z, et al. Am J Hum Genet. 2023 Mar 2;110(3):419-426. doi: 10.1016/j.ajhg.2023.01.018. Am J Hum Genet. 2023. PMID: 36868206 Free PMC article. Review.
In the first five years of operation, Australian Genomics has evaluated the outcomes of genomic testing in more than 5,200 individuals across 19 rare disease and cancer flagship studies. Comprehensive analyses of the health economic, policy, ethical, legal, implementation …
In the first five years of operation, Australian Genomics has evaluated the outcomes of genomic testing in more than 5,200 individuals acros …
Bilateral lymphadenopathies on mammograms: a case of mixed connective tissue disease and psoriatic arthropathy.
Giambersio E, Magni V, Sardanelli F. Giambersio E, et al. BJR Case Rep. 2023 Jan 23;9(2):20220077. doi: 10.1259/bjrcr.20220077. eCollection 2023 Mar. BJR Case Rep. 2023. PMID: 36998332 Free PMC article.
., increase in size or density) of lymph nodes in the armpit, caused by malignant diseases such as metastases (mainly from primary breast cancer), lymphoma, or leukaemia as well as benign conditions such as infectious or autoimmune systemic diseases. . …
., increase in size or density) of lymph nodes in the armpit, caused by malignant diseases such as metastases (mainly from primary …
Detection of microcalcifications in photon-counting dedicated breast-CT using a deep convolutional neural network: Proof of principle.
Landsmann A, Ruppert C, Borkowski K, Hejduk P, Ciritsis A, Wieler J, Rossi C, Boss A. Landsmann A, et al. Clin Imaging. 2023 Mar;95:28-36. doi: 10.1016/j.clinimag.2022.12.006. Epub 2022 Dec 28. Clin Imaging. 2023. PMID: 36603416 Free article.
OBJECTIVE: In this study, we investigate the feasibility of a deep Convolutional Neural Network (dCNN), trained with mammographic images, to detect and classify microcalcifications (MC) in breast-CT (BCT) images. METHODS: This retrospective single-center study was approved …
OBJECTIVE: In this study, we investigate the feasibility of a deep Convolutional Neural Network (dCNN), trained with mammographic images, to …
Benign Breast Disease, NSAIDs, and Postmenopausal Breast Cancer Risk in the CPS-II Cohort.
Sherman ME, Vierkant RA, Masters M, Radisky DC, Winham SJ, Degnim AC, Vachon CM, Patel AV, Teras LR. Sherman ME, et al. Cancer Prev Res (Phila). 2023 Mar 1;16(3):175-184. doi: 10.1158/1940-6207.CAPR-22-0403. Cancer Prev Res (Phila). 2023. PMID: 36596665 Free PMC article.
ABSTRACT: Nonsteroidal anti-inflammatory agents (NSAID) are associated with modest inconsistent reductions in breast cancer risk in population-based cohorts, whereas two focused studies of patients with benign breast disease (BBD) have found lower risk …
ABSTRACT: Nonsteroidal anti-inflammatory agents (NSAID) are associated with modest inconsistent reductions in breast cancer risk in p …
Algorithmic transparency and interpretability measures improve radiologists' performance in BI-RADS 4 classification.
Jungmann F, Ziegelmayer S, Lohoefer FK, Metz S, Müller-Leisse C, Englmaier M, Makowski MR, Kaissis GA, Braren RF. Jungmann F, et al. Eur Radiol. 2023 Mar;33(3):1844-1851. doi: 10.1007/s00330-022-09165-9. Epub 2022 Oct 25. Eur Radiol. 2023. PMID: 36282311 Free PMC article.
METHODS: In this retrospective observer study, four radiologists were asked to classify Breast Imaging-Reporting and Data System 4 (BI-RADS4) lesions (n = 101 benign, n = 99 malignant). ...
METHODS: In this retrospective observer study, four radiologists were asked to classify Breast Imaging-Reporting and Data System 4 (B …
The nipple-areolar complex: anatomy, methods and pathologic findings, between senologist and dermatologist.
Luigi B, Carlo V, Corrado C, Orlando C. Luigi B, et al. J Ultrasound. 2023 Mar;26(1):239-247. doi: 10.1007/s40477-022-00722-y. Epub 2022 Sep 9. J Ultrasound. 2023. PMID: 36085438 Free PMC article.
The purpose of this presentation is to show the ultrasonography findings of normal variants and benign and malignant diseases that affect the nipple-areolar complex. ...We will show you a combined clinical and radiological approach to evaluate the nipple-areolar com …
The purpose of this presentation is to show the ultrasonography findings of normal variants and benign and malignant diseases
Multiple cholesterol granulomas of the breast: A case report and review of the literature.
Jin M, Wu Q, Miao B, Jin J, Gao C, Xu X, Luo Y, Chen Z. Jin M, et al. Medicine (Baltimore). 2023 Feb 22;102(8):e33084. doi: 10.1097/MD.0000000000033084. Medicine (Baltimore). 2023. PMID: 36827045 Free article. Review.
RATIONALE: Cholesterol granuloma of the breast is a rare disease defined as chronic reactive inflammation of cholesterol crystals and foreign body giant cells. ...DIAGNOSES: The patient was confirmed to have a final diagnosis of benign cholesterol granulomas …
RATIONALE: Cholesterol granuloma of the breast is a rare disease defined as chronic reactive inflammation of cholesterol cryst …
Biomineralogical signatures of breast microcalcifications.
Kunitake JAMR, Sudilovsky D, Johnson LM, Loh HC, Choi S, Morris PG, Jochelson MS, Iyengar NM, Morrow M, Masic A, Fischbach C, Estroff LA. Kunitake JAMR, et al. Sci Adv. 2023 Feb 22;9(8):eade3152. doi: 10.1126/sciadv.ade3152. Epub 2023 Feb 22. Sci Adv. 2023. PMID: 36812311 Free PMC article.
Microcalcifications, primarily biogenic apatite, occur in cancerous and benign breast pathologies and are key mammographic indicators. Outside the clinic, numerous microcalcification compositional metrics (e.g., carbonate and metal content) are linked to malignancy, …
Microcalcifications, primarily biogenic apatite, occur in cancerous and benign breast pathologies and are key mammographic ind …
Potential Early Markers for Breast Cancer: A Proteomic Approach Comparing Saliva and Serum Samples in a Pilot Study.
Sinha I, Fogle RL, Gulfidan G, Stanley AE, Walter V, Hollenbeak CS, Arga KY, Sinha R. Sinha I, et al. Int J Mol Sci. 2023 Feb 19;24(4):4164. doi: 10.3390/ijms24044164. Int J Mol Sci. 2023. PMID: 36835577 Free PMC article.
We sought to identify protein markers in saliva and serum for early detection of breast cancer. A rigorous analysis was performed for individual saliva and serum samples from women without breast disease, and women diagnosed with benign or malignant …
We sought to identify protein markers in saliva and serum for early detection of breast cancer. A rigorous analysis was performed for …
Real-World Evidence: How Long Do Our Patients Fast?-Results from a Prospective JAGO-NOGGO-Multicenter Analysis on Perioperative Fasting in 924 Patients with Malignant and Benign Gynecological Diseases.
Beck MH, Balci-Hakimeh D, Scheuerecker F, Wallach C, Güngor HL, Lee M, Abdel-Kawi AF, Glajzer J, Vasiljeva J, Kubiak K, Blohmer JU, Sehouli J, Pietzner K. Beck MH, et al. Cancers (Basel). 2023 Feb 18;15(4):1311. doi: 10.3390/cancers15041311. Cancers (Basel). 2023. PMID: 36831652 Free PMC article.
Virtual elastography ultrasound via generative adversarial network for breast cancer diagnosis.
Yao Z, Luo T, Dong Y, Jia X, Deng Y, Wu G, Zhu Y, Zhang J, Liu J, Yang L, Luo X, Li Z, Xu Y, Hu B, Huang Y, Chang C, Xu J, Luo H, Dong F, Xia X, Wu C, Hu W, Wu G, Li Q, Chen Q, Deng W, Jiang Q, Mou Y, Yan H, Xu X, Yan H, Zhou P, Shao Y, Cui L, He P, Qian L, Liu J, Shi L, Zhao Y, Xu Y, Zhan W, Wang Y, Yu J, Zhou J. Yao Z, et al. Nat Commun. 2023 Feb 11;14(1):788. doi: 10.1038/s41467-023-36102-1. Nat Commun. 2023. PMID: 36774357 Free PMC article.
Here we show a cost-efficient solution by designing a deep neural network to synthesize virtual EUS (V-EUS) from conventional B-mode images. A total of 4580 breast tumor cases were collected from 15 medical centers, including a main cohort with 2501 cases for model establi …
Here we show a cost-efficient solution by designing a deep neural network to synthesize virtual EUS (V-EUS) from conventional B-mode images. …
Study on the correlation between B vitamins and breast cancer.
Xie S, Tan M, Li H, Li L, Zhang H, Wang Q, Li S, Yang J, Xie H, Chen P, Liu D, Guo R, Tang S. Xie S, et al. Cancer Cell Int. 2023 Feb 9;23(1):22. doi: 10.1186/s12935-023-02860-7. Cancer Cell Int. 2023. PMID: 36759846 Free PMC article.
METHODS: The study used liquid chromatography-tandem mass spectrometry to determine the serum vitamin levels of 520 people who attended Yunnan Cancer Hospital from September 2020 to December 2020. After screening by exclusion criteria, 38 patients with benign breast
METHODS: The study used liquid chromatography-tandem mass spectrometry to determine the serum vitamin levels of 520 people who attended Yunn …
Combined fine-needle aspiration and selective intraoperative frozen section to optimize prediction of malignant thyroid nodules: A retrospective cohort study of more than 3000 patients.
Mao Z, Ding Y, Wen L, Zhang Y, Wu G, You Q, Wu J, Luo D, Teng L, Wang W. Mao Z, et al. Front Endocrinol (Lausanne). 2023 Feb 6;14:1091200. doi: 10.3389/fendo.2023.1091200. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 36814578 Free PMC article.
BACKGROUND: Preoperative fine-needle aspiration (FNA) is widely used to differentiate malignant from benign thyroid nodules, while intraoperative frozen sections (FS) are suggested as a systematic supplement for intraoperative decision-making, but limitations still remain …
BACKGROUND: Preoperative fine-needle aspiration (FNA) is widely used to differentiate malignant from benign thyroid nodules, while in …
Towards precision medicine based on a continuous deep learning optimization and ensemble approach.
Li J, Jin L, Wang Z, Peng Q, Wang Y, Luo J, Zhou J, Cao Y, Zhang Y, Zhang M, Qiu Y, Hu Q, Chen L, Yu X, Zhou X, Li Q, Zhou S, Huang S, Luo D, Mao X, Yu Y, Yang X, Pan C, Li H, Wang J, Liao J. Li J, et al. NPJ Digit Med. 2023 Feb 3;6(1):18. doi: 10.1038/s41746-023-00759-1. NPJ Digit Med. 2023. PMID: 36737644 Free PMC article.
We developed a continuous learning system (CLS) based on deep learning and optimization and ensemble approach, and conducted a retrospective data simulated prospective study using ultrasound images of breast masses for precise diagnoses. We extracted 629 breast mass …
We developed a continuous learning system (CLS) based on deep learning and optimization and ensemble approach, and conducted a retrospective …
Ductal carcinoma in situ of the breast arising in a solitary intraductal papilloma.
Badrawi N, AlSayegh AA. Badrawi N, et al. Radiol Case Rep. 2022 Nov 23;18(2):449-451. doi: 10.1016/j.radcr.2022.11.014. eCollection 2023 Feb. Radiol Case Rep. 2022. PMID: 36439917 Free PMC article.
Ductal disease is a broad group encompassing both benign and malignant entities which may overlap clinically and radiologically. Ductal carcinoma in situ (DCIS) is a noninvasive breast malignancy accounting for 20% of newly diagnosed breast cancer case …
Ductal disease is a broad group encompassing both benign and malignant entities which may overlap clinically and radiologicall …
The capillary lobule variant of radiation-associated angiosarcoma in the setting of breast cancer: A diagnostic pitfall.
Agrawal S, Fritchie KJ, Fernandez AP, Ko JS, Bergfeld W, Rubin BP, Billings SD. Agrawal S, et al. J Cutan Pathol. 2023 Feb;50(2):140-146. doi: 10.1111/cup.14328. Epub 2022 Oct 10. J Cutan Pathol. 2023. PMID: 36107728 Free PMC article.
AIM: Post-radiation angiosarcoma is an iatrogenic event seen in the setting of breast cancer treatment. Histopathologically, there are morphologic variants of angiosarcoma that mimic benign entities, including the capillary lobule variant of post-radiation angiosarc …
AIM: Post-radiation angiosarcoma is an iatrogenic event seen in the setting of breast cancer treatment. Histopathologically, there ar …
Non-oncologic incidental uptake on FAPI PET/CT imaging.
Hotta M, Rieger AC, Jafarvand MG, Menon N, Farolfi A, Benz MR, Calais J. Hotta M, et al. Br J Radiol. 2023 Feb;96(1142):20220463. doi: 10.1259/bjr.20220463. Epub 2022 Jul 13. Br J Radiol. 2023. PMID: 35776566 Free PMC article. Review.
FAPI PET uptake has been reported in various conditions such as benign tumors, fibrotic, granulomatosis, scarring/wound, degenerative diseases, and inflammatory diseases.The knowledge of physiological and non-oncologic causes of FAPI uptake is indispensable f …
FAPI PET uptake has been reported in various conditions such as benign tumors, fibrotic, granulomatosis, scarring/wound, degenerative …
MicroRNA and Messenger RNA Expression Profiles in Canine Mammary Gland Tumor.
Kim EP, Jang G, Kim JW, Kim SW, Chung H, Yang YJ, Kim WH, Kim GA. Kim EP, et al. Int J Mol Sci. 2023 Jan 30;24(3):2618. doi: 10.3390/ijms24032618. Int J Mol Sci. 2023. PMID: 36768939 Free PMC article.
In this study, we analyzed differentially expressed microRNAs followed by RNA-Seq to investigate the alterations in mRNA levels based on the malignancy (benign, malignant) and the biopsy locations (tumors, surrounding normal tissues). We identified multiple breast c …
In this study, we analyzed differentially expressed microRNAs followed by RNA-Seq to investigate the alterations in mRNA levels based on the …
Classification of benign and malignant subtypes of breast cancer histopathology imaging using hybrid CNN-LSTM based transfer learning.
Srikantamurthy MM, Rallabandi VPS, Dudekula DB, Natarajan S, Park J. Srikantamurthy MM, et al. BMC Med Imaging. 2023 Jan 30;23(1):19. doi: 10.1186/s12880-023-00964-0. BMC Med Imaging. 2023. PMID: 36717788 Free PMC article.
Recent deep learning methods for medical image analysis suggest the utility of automated radiologic imaging classification for relating disease characteristics or diagnosis and patient stratification. METHODS: To develop a hybrid model using the convolutional neural networ …
Recent deep learning methods for medical image analysis suggest the utility of automated radiologic imaging classification for relating d
Mammography in Breast Disease Screening and Diagnosis.
Tari DU, Pinto F. Tari DU, et al. J Pers Med. 2023 Jan 27;13(2):228. doi: 10.3390/jpm13020228. J Pers Med. 2023. PMID: 36836462 Free PMC article.
Female breasts can suffer from a wide spectrum of pathologies, ranging from inflammatory diseases to benign and malignant tumors [...]....
Female breasts can suffer from a wide spectrum of pathologies, ranging from inflammatory diseases to benign and malignant tumo …
Species-Level Characterization of the Microbiome in Breast Tissues with Different Malignancy and Hormone-Receptor Statuses Using Nanopore Sequencing.
Luo L, Fu A, Shi M, Hu J, Kong D, Liu T, Yuan J, Sun S, Chen C. Luo L, et al. J Pers Med. 2023 Jan 19;13(2):174. doi: 10.3390/jpm13020174. J Pers Med. 2023. PMID: 36836409 Free PMC article.
Unambiguous evidence indicates that microbes are closely linked to various human diseases, including cancer. Most prior work investigating the microbiome of breast tissue describes an association between compositional differences of microbial species in benign
Unambiguous evidence indicates that microbes are closely linked to various human diseases, including cancer. Most prior work investig …
Gynecomastia: Etiology, Diagnosis, and Treatment.
Swerdloff RS, Ng JCM. Swerdloff RS, et al. 2023 Jan 6. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. 2023 Jan 6. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 25905330 Free Books & Documents. Review.
Gynecomastia is a relatively common disorder. Its causes range from benign physiological processes to rare neoplasms. To diagnose the etiology of the gynecomastia, the clinician must understand the hormonal factors involved in breast development. Parallel to female …
Gynecomastia is a relatively common disorder. Its causes range from benign physiological processes to rare neoplasms. To diagnose the …
[Methods for fertility preservation].
Rodriguez-Wallberg K. Rodriguez-Wallberg K. Lakartidningen. 2023 Jan 4;120:22071. Lakartidningen. 2023. PMID: 36598163 Free article. Swedish.
The largest patient groups undergoing procedures for fertility preservation include those with a cancer diagnosis, but also individuals with benign diseases, gender dysphoria and genetic conditions facing infertility risk may be offered fertility preservation. ...Th …
The largest patient groups undergoing procedures for fertility preservation include those with a cancer diagnosis, but also individuals with …
A Rare Case of Granulomatous Mastitis Associated With Positive Systemic Lupus Erythematosus Serology in a Young Female Patient: A Case Report and Literature Review.
Abdalla MS, Saad E, Abdulrahman A, Abdulrahman AA, Mokhtar M, Mohamed K. Abdalla MS, et al. Cureus. 2023 Jan 2;15(1):e33279. doi: 10.7759/cureus.33279. eCollection 2023 Jan. Cureus. 2023. PMID: 36741602 Free PMC article.
Granulomatous mastitis (GM) is a rare benign breast disease that affects women of childbearing age, usually within five years of pregnancy. ...Further laboratory workup revealed evidence of some immunological criteria of SLE. Steroid therapy led to the resolu …
Granulomatous mastitis (GM) is a rare benign breast disease that affects women of childbearing age, usually within five …
Cholesterol Granuloma of the Breast Mimicking Cancer: A Case Report and Review of the Literature.
Lahbacha B, Chaabane A, Chelly B, Douggaz A, Mfarrej MK, Jbir I, Nechi S, Chelbi E. Lahbacha B, et al. J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231193275. doi: 10.1177/23247096231193275. J Investig Med High Impact Case Rep. 2023. PMID: 37565689 Free PMC article. Review.
Cholesterol granuloma of the breast is an infrequent benign lesion with clinical and radiological findings suggestive of cancer. ...Despite the alarming radiologic features, microscopic findings were consistent with breast cholesterol granuloma....
Cholesterol granuloma of the breast is an infrequent benign lesion with clinical and radiological findings suggestive of cance …
Deep learning for differentiating benign from malignant tumors on breast-specific gamma image.
Yu X, Dong M, Yang D, Wang L, Wang H, Ma L. Yu X, et al. Technol Health Care. 2023;31(S1):61-67. doi: 10.3233/THC-236007. Technol Health Care. 2023. PMID: 37038782 Free PMC article.
BACKGROUND: Breast diseases are a significant health threat for women. With the fast-growing BSGI data, it is becoming increasingly critical for physicians to accurately diagnose benign as well as malignant breast tumors. OBJECTIVE: The purpose of this …
BACKGROUND: Breast diseases are a significant health threat for women. With the fast-growing BSGI data, it is becoming increas …
Factors leading to delayed and challenging presentation of benign breast lumps in young females.
Saleem S, Tariq S, Tariq S, Irfan S, Javed F. Saleem S, et al. Pak J Med Sci. 2023 Jan-Feb;39(1):80-85. doi: 10.12669/pjms.39.1.6647. Pak J Med Sci. 2023. PMID: 36694785 Free PMC article.
BACKGROUND AND OBJECTIVE: A delayed presentation of benign breast diseases may lead to a therapeutic challenge when they enlarge enormously or become multiple. ...All the sub-scales of stigma, i.e., social rejection, financial insecurity, internalized shame a …
BACKGROUND AND OBJECTIVE: A delayed presentation of benign breast diseases may lead to a therapeutic challenge when the …
Cell Blocks from Ultrasound Guided Fine Needle Aspirates: Diagnostic Yield in a Series of 51 Dermatologic Lesions.
Laverde-Saad A, Nájera Botello L, Salgüero Fernandez I, Turrión Merino L, Roustan Gullón G, Alfageme Roldan F. Laverde-Saad A, et al. Actas Dermosifiliogr. 2023 Jan;114(1):T69-T72. doi: 10.1016/j.ad.2022.01.052. Epub 2022 Nov 10. Actas Dermosifiliogr. 2023. PMID: 36372113 Free article. Review. English, Spanish.
The generation of cell blocks (CBs) obtained from ultrasound-guided fine needle aspiration biopsies (USFNAB) is a well-established technique in breast and thyroid pathology, but is rarely used in dermatology. We reviewed CBs obtained from USFNAB of skin lesions, which were …
The generation of cell blocks (CBs) obtained from ultrasound-guided fine needle aspiration biopsies (USFNAB) is a well-established technique …
Clinical Implications and Management of Non-BIA-ALCL Breast Implant Capsular Pathology.
Vorstenbosch J, Chu JJ, Ariyan CE, McCarthy CM, Disa JJ, Nelson JA. Vorstenbosch J, et al. Plast Reconstr Surg. 2023 Jan 1;151(1):20e-30e. doi: 10.1097/PRS.0000000000009780. Epub 2022 Oct 4. Plast Reconstr Surg. 2023. PMID: 36194076 Free PMC article. Review.
Although normally benign, increased awareness of breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) highlights that disease may arise from the capsule. ...Several benign and malignant breast implant capsular diseases can …
Although normally benign, increased awareness of breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) highlight …
Cell Blocks from Ultrasound Guided Fine Needle Aspirates: Diagnostic Yield in a Series of 51 Dermatologic Lesions.
Laverde-Saad A, Nájera Botello L, Salgüero Fernandez I, Turrión Merino L, Roustan Gullón G, Alfageme Roldan F. Laverde-Saad A, et al. Actas Dermosifiliogr. 2023 Jan;114(1):69-72. doi: 10.1016/j.ad.2022.01.044. Epub 2022 Jun 26. Actas Dermosifiliogr. 2023. PMID: 35760095 Free article. Review. English, Spanish.
The generation of cell blocks (CB) obtained from ultrasound-guided fine needle aspiration biopsies (USFNAB) is a well-established technique in breast and thyroid pathology, but is rarely used in dermatology. We reviewed CBs obtained from USFNAB of skin lesions, which were …
The generation of cell blocks (CB) obtained from ultrasound-guided fine needle aspiration biopsies (USFNAB) is a well-established technique …
A Multi-Stage Approach to Breast Cancer Classification Using Histopathology Images.
Bagchi A, Pramanik P, Sarkar R. Bagchi A, et al. Diagnostics (Basel). 2022 Dec 30;13(1):126. doi: 10.3390/diagnostics13010126. Diagnostics (Basel). 2022. PMID: 36611418 Free PMC article.
Breast cancer is one of the deadliest diseases worldwide among women. Early diagnosis and proper treatment can save many lives. Breast image analysis is a popular method for detecting breast cancer. ...
Breast cancer is one of the deadliest diseases worldwide among women. Early diagnosis and proper treatment can save many lives
Enhancement of Mammographic Images Using Histogram-Based Techniques for Their Classification Using CNN.
Alshamrani K, Alshamrani HA, Alqahtani FF, Almutairi BS. Alshamrani K, et al. Sensors (Basel). 2022 Dec 26;23(1):235. doi: 10.3390/s23010235. Sensors (Basel). 2022. PMID: 36616832 Free PMC article.
This kind of examination enables the detection of abnormalities in breast tissue, such as masses and microcalcifications, which are thought to be indicators of the presence of disease. This study aims to determine how histogram-based image enhancement methods affect …
This kind of examination enables the detection of abnormalities in breast tissue, such as masses and microcalcifications, which are t …
Pituitary tumors and the risk of other malignancies: is the relationship coincidental or causal?
Pekic S, Stojanovic M, Popovic V. Pekic S, et al. Endocr Oncol. 2022 Dec 22;2(1):R1-R13. doi: 10.1530/EO-21-0033. eCollection 2022 Jan. Endocr Oncol. 2022. PMID: 37435457 Free PMC article. Review.
Pituitary adenomas are benign neoplasms of the pituitary. The most prevalent are prolactinomas and non-functioning pituitary adenomas, followed by growth hormone- and ACTH-secreting adenomas. ...They found an association of pituitary tumors with positive family history for …
Pituitary adenomas are benign neoplasms of the pituitary. The most prevalent are prolactinomas and non-functioning pituitary adenomas …
[Idiopathic granulomatous mastitis associated with erythema nodosum: a case report].
Conte AB, Alaoui FZF, Jayi S, Chaara H, Melhouf MA. Conte AB, et al. Pan Afr Med J. 2022 Dec 16;43:196. doi: 10.11604/pamj.2022.43.196.26754. eCollection 2022. Pan Afr Med J. 2022. PMID: 36942131 Free PMC article. French.
Idiopathic granulomatous mastitis (IMD) is a chronic benign inflammatory disease of the breast which can mimic breast cancer. It is more common in young women of childbearing age and poses a challenge in diagnosis of inflammatory breast tumor. W …
Idiopathic granulomatous mastitis (IMD) is a chronic benign inflammatory disease of the breast which can mimic breas
Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies.
Hatchwell E, Smith EB 3rd, Jalilzadeh S, Bruno CD, Taoufik Y, Hendel-Chavez H, Liblau R, Brassat D, Martin-Blondel G, Wiendl H, Schwab N, Cortese I, Monaco MC, Imberti L, Capra R, Oksenberg JR, Gasnault J, Stankoff B, Richmond TA, Rancour DM, Koralnik IJ, Hanson BA, Major EO, Chow CR, Eis PS. Hatchwell E, et al. Front Neurol. 2022 Dec 14;13:1016377. doi: 10.3389/fneur.2022.1016377. eCollection 2022. Front Neurol. 2022. PMID: 36588876 Free PMC article.
In some patients, iatrogenic (i.e., drug-induced) PML occurs as a serious adverse event from exposure to immunosuppressant therapies used to treat their disease (e.g., hematological malignancies and multiple sclerosis). ...CONCLUSION: For the first time, a PML genetic risk …
In some patients, iatrogenic (i.e., drug-induced) PML occurs as a serious adverse event from exposure to immunosuppressant therapies used to …
Quantitative Assessment of Breast-Tumor Stiffness Using Shear-Wave Elastography Histograms.
Papageorgiou I, Valous NA, Hadjidemetriou S, Teichgräber U, Malich A. Papageorgiou I, et al. Diagnostics (Basel). 2022 Dec 13;12(12):3140. doi: 10.3390/diagnostics12123140. Diagnostics (Basel). 2022. PMID: 36553148 Free PMC article.
This study proposes a histogram-based SWE analysis to improve breast malignancy detection. Methods: N = 22/32 (patients/tumors) benign and n = 51/64 malignant breast tumors with histological ground truth. ...Results: The SWEavg and SWEmax did not discriminate …
This study proposes a histogram-based SWE analysis to improve breast malignancy detection. Methods: N = 22/32 (patients/tumors) be
Genotype-phenotype associations in a large PTEN Hamartoma Tumor Syndrome (PHTS) patient cohort.
Hendricks LAJ, Hoogerbrugge N, Venselaar H, Aretz S, Spier I, Legius E, Brems H, de Putter R, Claes KBM, Evans DG, Woodward ER, Genuardi M, Brugnoletti F, van Ierland Y, Dijke K, Tham E, Tesi B, Schuurs-Hoeijmakers JHM, Branchaud M, Salvador H, Jahn A, Schnaiter S, Anastasiadou VC, Brunet J, Oliveira C, Roht L, Blatnik A, Irmejs A; PTEN Study Group; Mensenkamp AR, Vos JR. Hendricks LAJ, et al. Eur J Med Genet. 2022 Dec;65(12):104632. doi: 10.1016/j.ejmg.2022.104632. Epub 2022 Oct 18. Eur J Med Genet. 2022. PMID: 36270489 Free article.
BACKGROUND: Pathogenic PTEN germline variants cause PTEN Hamartoma Tumor Syndrome (PHTS), a rare disease with a variable genotype and phenotype. Knowledge about these spectra and genotype-phenotype associations could help diagnostics and potentially lead to personalized ca …
BACKGROUND: Pathogenic PTEN germline variants cause PTEN Hamartoma Tumor Syndrome (PHTS), a rare disease with a variable genotype and …
Evaluation of complications, conversion rate, malignancy rate, and, surgeon's experience in laparoscopic assisted supracervical hysterectomy (LASH) of 1274 large uteri: A retrospective study.
Tchartchian G, Bojahr B, Krentel H, De Wilde RL. Tchartchian G, et al. Acta Obstet Gynecol Scand. 2022 Dec;101(12):1450-1457. doi: 10.1111/aogs.14468. Epub 2022 Oct 6. Acta Obstet Gynecol Scand. 2022. PMID: 36203317 Free PMC article.
MATERIAL AND METHODS: The present retrospective study, between June 27, 1998 and August 31, 2019, evaluates 1274 patients with a uterus weight over 500 g who were treated with LASH for benign uterine diseases at the Clinic for Minimal Invasive Surgery (Berlin, Germa …
MATERIAL AND METHODS: The present retrospective study, between June 27, 1998 and August 31, 2019, evaluates 1274 patients with a uterus weig …
Non-glandular findings on breast ultrasound. Part I: a pictorial review of superficial lesions.
Caruso M, Catalano O, Bard R, Varelli C, Corvino F, Caiazzo C, Corvino A. Caruso M, et al. J Ultrasound. 2022 Dec;25(4):783-797. doi: 10.1007/s40477-021-00619-2. Epub 2022 Apr 19. J Ultrasound. 2022. PMID: 35438461 Free PMC article. Review.
In this setting, the radiologist must be familiar with the non-glandular breast diseases, which can occur in the superficial layers as well as in the chest wall. ...They may be located in the dermis or hypodermis: the former are usually benign skin lesions, w …
In this setting, the radiologist must be familiar with the non-glandular breast diseases, which can occur in the superficial l …
Breast Cancer Classification by Using Multi-Headed Convolutional Neural Network Modeling.
Pathan RK, Alam FI, Yasmin S, Hamd ZY, Aljuaid H, Khandaker MU, Lau SL. Pathan RK, et al. Healthcare (Basel). 2022 Nov 25;10(12):2367. doi: 10.3390/healthcare10122367. Healthcare (Basel). 2022. PMID: 36553891 Free PMC article.
Breast cancer is one of the most widely recognized diseases after skin cancer. ...In this study, artificial intelligence was used to rapidly detect breast cancer by analyzing ultrasound images from the Breast Ultrasound Images Dataset (BUSI), which con
Breast cancer is one of the most widely recognized diseases after skin cancer. ...In this study, artificial intelligence was u
Are contrast enhanced mammography and digital breast tomosynthesis equally effective in diagnosing patients recalled from breast cancer screening?
Siminiak N, Pasiuk-Czepczyńska A, Godlewska A, Wojtyś P, Olejnik M, Michalak J, Nowaczyk P, Gajdzis P, Godlewski D, Ruchała M, Czepczyński R. Siminiak N, et al. Front Oncol. 2022 Nov 24;12:941312. doi: 10.3389/fonc.2022.941312. eCollection 2022. Front Oncol. 2022. PMID: 36505843 Free PMC article.
Contrast enhanced mammography (CEM) and digital breast tomosynthesis (DBT) are used in the diagnostic setting, however their accuracies need to be compared.The aim of the study was to evaluate the diagnostic performance of CEM and DBT in women recalled from breast c …
Contrast enhanced mammography (CEM) and digital breast tomosynthesis (DBT) are used in the diagnostic setting, however their accuraci …
Uncertainty Ordinal Multi-Instance Learning for Breast Cancer Diagnosis.
Xu X, Guo Q, Li Z, Li D. Xu X, et al. Healthcare (Basel). 2022 Nov 17;10(11):2300. doi: 10.3390/healthcare10112300. Healthcare (Basel). 2022. PMID: 36421624 Free PMC article.
Ordinal multi-instance learning (OMIL) deals with the weak supervision scenario wherein instances in each training bag are not only multi-class but also have rank order relationships between classes, such as breast cancer, which has become one of the most frequent disea
Ordinal multi-instance learning (OMIL) deals with the weak supervision scenario wherein instances in each training bag are not only multi-cl …
Cell membrane-coated human hair nanoparticles for precise disease therapies.
Zhang Y, Li Y, Xia Q, Li Y, Jin S, Mao Q, Liu C, Fan X, Lin H. Zhang Y, et al. J Nanobiotechnology. 2022 Nov 16;20(1):480. doi: 10.1186/s12951-022-01673-6. J Nanobiotechnology. 2022. PMID: 36384635 Free PMC article.
Precision medicine is the ultimate goal for current disease therapies, including tumor and infection. The lack of specific targeted drugs for liver cancer and the lack of specific anti-infective drugs in the treatment of diabetic foot ulcer with infection (DFI) are the rep …
Precision medicine is the ultimate goal for current disease therapies, including tumor and infection. The lack of specific targeted d …
Biomedical Indicators of Patients with Non-Puerperal Mastitis: A Retrospective Study.
Shi L, Wu J, Hu Y, Zhang X, Li Z, Xi PW, Wei JF, Ding Q. Shi L, et al. Nutrients. 2022 Nov 14;14(22):4816. doi: 10.3390/nu14224816. Nutrients. 2022. PMID: 36432503 Free PMC article.
METHODS: Overall, 284 patients diagnosed with NPM were consecutively recruited as cases in this study, and patients with benign breast disease (n = 1128) were enrolled as control. The clinical, biomedical, and pathological indicators were analyzed. ...The dif …
METHODS: Overall, 284 patients diagnosed with NPM were consecutively recruited as cases in this study, and patients with benign br
Long non-coding RNAs as novel prognostic biomarkers for breast cancer in Egyptian women.
El-Helkan B, Emam M, Mohanad M, Fathy S, Zekri AR, Ahmed OS. El-Helkan B, et al. Sci Rep. 2022 Nov 14;12(1):19498. doi: 10.1038/s41598-022-23938-8. Sci Rep. 2022. PMID: 36376369 Free PMC article.
Our study included 75 women recently diagnosed with BC and 25 healthy women as normal controls. Patients were divided into three groups: 24 with benign breast diseases, 28 with metastatic breast cancer (MBC, stage IV), and 23 with non-metastatic bre
Our study included 75 women recently diagnosed with BC and 25 healthy women as normal controls. Patients were divided into three groups: 24 …
Plasma Levels of CXC Motif Chemokine 1 (CXCL1) and Chemokine 8 (CXCL8) as Diagnostic Biomarkers in Luminal A and B Breast Cancer.
Motyka J, Gacuta E, Kicman A, Kulesza M, Ławicki P, Ławicki S. Motyka J, et al. J Clin Med. 2022 Nov 12;11(22):6694. doi: 10.3390/jcm11226694. J Clin Med. 2022. PMID: 36431173 Free PMC article.
CXCL1 and CXCL8 belong to the ELR-motif-containing group of CXC chemokines, which, in breast cancer (BC), stimulate angiogenesis and increase migration and invasiveness of tumor cells. ...The study group consisted of 100 patients with BC, and the control group of 50 subjec …
CXCL1 and CXCL8 belong to the ELR-motif-containing group of CXC chemokines, which, in breast cancer (BC), stimulate angiogenesis and …
Benign Breast Disease in Makkah, Saudi Arabia: A Retrospective Analytical Cross-Sectional Study.
Almatrafi MI, Almalki MA, Althagafi JA, AlSindi TS, Masarit RM, Almatrafi RM. Almatrafi MI, et al. Cureus. 2022 Nov 6;14(11):e31174. doi: 10.7759/cureus.31174. eCollection 2022 Nov. Cureus. 2022. PMID: 36514593 Free PMC article.
Introduction The most frequent reason for visiting breast clinics is benign breast disease (BBD), which accounts for 90% of all breast-related presentations globally. It is widespread among women of childbearing age, peaking between the ages of …
Introduction The most frequent reason for visiting breast clinics is benign breast disease (BBD), which accounts …
Sclerosing Adenosis of the Prostate-A Benign Lesion Similar to Prostate Cancer: A Case Report and Literature Review.
Yao H, Tang G, Cui Y, Wu J. Yao H, et al. Am J Mens Health. 2022 Nov-Dec;16(6):15579883221143182. doi: 10.1177/15579883221143182. Am J Mens Health. 2022. PMID: 36527372 Free PMC article. Review.
Sclerosing adenosis of the prostate (SAP) is a rare benign non-neoplastic small acinar hyperplasia. Like sclerosing adenosis of the breast, which is confused with breast cancer, SAP is a trap in the pathological differential diagnosis of benign and mal …
Sclerosing adenosis of the prostate (SAP) is a rare benign non-neoplastic small acinar hyperplasia. Like sclerosing adenosis of the …
Distinct molecular subtypes of papillary thyroid carcinoma and gene signature with diagnostic capability.
Hong S, Xie Y, Cheng Z, Li J, He W, Guo Z, Zhang Q, Peng S, He M, Yu S, Xu L, Liu R, Xu T, Zhang Y, Li Y, Wang J, Lv W, Yu J, Xiao H. Hong S, et al. Oncogene. 2022 Nov;41(47):5121-5132. doi: 10.1038/s41388-022-02499-0. Epub 2022 Oct 17. Oncogene. 2022. PMID: 36253446 Free PMC article.
We integrated transcriptomic sequencing, genomic analysis and clinicopathologic information from 582 tissue samples of 216 PTC and 75 benign thyroid nodule (BTN) patients. We discovered four subtypes of PTC including Immune-enriched Subtype, BRAF-enriched Subtype, Stromal …
We integrated transcriptomic sequencing, genomic analysis and clinicopathologic information from 582 tissue samples of 216 PTC and 75 ben
MARGINAL: An Automatic Classification of Variants in BRCA1 and BRCA2 Genes Using a Machine Learning Model.
Karalidou V, Kalfakakou D, Papathanasiou A, Fostira F, Matsopoulos GK. Karalidou V, et al. Biomolecules. 2022 Oct 24;12(11):1552. doi: 10.3390/biom12111552. Biomolecules. 2022. PMID: 36358902 Free PMC article.
Implementation of next-generation sequencing (NGS) for the genetic analysis of hereditary diseases has resulted in a vast number of genetic variants identified daily, leading to inadequate variant interpretation and, consequently, a lack of useful clinical information for …
Implementation of next-generation sequencing (NGS) for the genetic analysis of hereditary diseases has resulted in a vast number of g …
Proteomics-Based Identification of Dysregulated Proteins in Breast Cancer.
Neagu AN, Jayathirtha M, Whitham D, Mutsengi P, Sullivan I, Petre BA, Darie CC. Neagu AN, et al. Proteomes. 2022 Oct 21;10(4):35. doi: 10.3390/proteomes10040035. Proteomes. 2022. PMID: 36278695 Free PMC article. Review.
Immunohistochemistry (IHC) is still widely used as a morphology-based assay for in situ analysis of target proteins as specific tumor antigens. However, as a very heterogeneous collection of neoplastic diseases, breast cancer (BC) requires an accurate identification …
Immunohistochemistry (IHC) is still widely used as a morphology-based assay for in situ analysis of target proteins as specific tumor antige …
Benign thyroid disease and the risk of breast cancer: An updated systematic review and meta-analysis.
Han M, Wang Y, Jin Y, Zhao X, Cui H, Wang G, Gang X. Han M, et al. Front Endocrinol (Lausanne). 2022 Oct 12;13:984593. doi: 10.3389/fendo.2022.984593. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36313770 Free PMC article.
BACKGROUND: The correlation between benign thyroid disease (BTD) and breast cancer (BC) has long been discussed. ...The current meta-analysis aimed at performing a comprehensive assessment of the relationship between different types of benign thyroid …
BACKGROUND: The correlation between benign thyroid disease (BTD) and breast cancer (BC) has long been discussed. ...The …
A Case of a Female Patient Presenting With Idiopathic Granulomatous Mastitis With Superimposed Enterococcus Avium Infection.
Albogami M, Alsaedy A, Matrood RA Sr, Alotaibi Y, Al Ahmadi B. Albogami M, et al. Cureus. 2022 Oct 6;14(10):e29997. doi: 10.7759/cureus.29997. eCollection 2022 Oct. Cureus. 2022. PMID: 36381742 Free PMC article.
Idiopathic granulomatous mastitis (IGM) is defined as an uncommon, benign, chronic inflammatory disease of unknown etiology that affects the breast and can mimic breast cancer. It usually manifests as a solid, ill-defined breast lump in postpart …
Idiopathic granulomatous mastitis (IGM) is defined as an uncommon, benign, chronic inflammatory disease of unknown etiology th …
Efficacy of digital breast tomosynthesis combined with magnetic resonance imaging in the diagnosis of early breast cancer.
Ren Y, Zhang J, Zhang JD, Xu JZ. Ren Y, et al. World J Clin Cases. 2022 Oct 6;10(28):10042-10052. doi: 10.12998/wjcc.v10.i28.10042. World J Clin Cases. 2022. PMID: 36246806 Free PMC article.
METHODS: This study was divided into two parts. Firstly, 110 patients with early breast cancer confirmed by pathological examination and 110 with benign breast diseases diagnosed simultaneously in Changzhi People's Hospital of Shanxi Province and Shanx …
METHODS: This study was divided into two parts. Firstly, 110 patients with early breast cancer confirmed by pathological examination …
Unexpectedly High Coexistence Rate of In Situ/Invasive Carcinoma In Phyllodes Tumors. 10-Year Retrospective and Review Study.
Gemci ÖD, Altınay S, İlbar Tartar R, Ferahman S. Gemci ÖD, et al. Eur J Breast Health. 2022 Oct 1;18(4):343-352. doi: 10.4274/ejbh.galenos.2022.2022-6-2. eCollection 2022 Oct. Eur J Breast Health. 2022. PMID: 36248757 Free PMC article.
RESULTS: A total of 29 patients diagnosed with PTs were identified, among whom 14 (48.2%) had benign PTs, 10 (34.4%) had borderline PTs, and 5 (17.2%) had malignant PTs. ...The coexistence of malignant PTs and carcinoma was significantly higher than those of benign
RESULTS: A total of 29 patients diagnosed with PTs were identified, among whom 14 (48.2%) had benign PTs, 10 (34.4%) had borderline P …
Epidermal inclusion cyst in male breast: how to differentiate from other male breast lesions.
Ak M, Yurtsever C, Cakir OF, Yurtsever N. Ak M, et al. Radiol Case Rep. 2022 Aug 12;17(10):3919-3922. doi: 10.1016/j.radcr.2022.07.097. eCollection 2022 Oct. Radiol Case Rep. 2022. PMID: 36032200 Free PMC article.
Male breast lesions are relatively less common. The most encountered malignant lesion in the male breast is ductal adenocarcinoma; and benign lesions are gynecomastia, fibrocystic disease, intramammary lymph node, fibroadenoma, lipoma and epider …
Male breast lesions are relatively less common. The most encountered malignant lesion in the male breast is ductal adenocarcin …
Breast calcification micromorphology classification.
Scott R, Lyburn I, Cornford E, Bouzy P, Stone N, Greenwood C, Bouybayoune I, Pinder S, Rogers K. Scott R, et al. Br J Radiol. 2022 Oct 1;95(1139):20220485. doi: 10.1259/bjr.20220485. Epub 2022 Jul 25. Br J Radiol. 2022. PMID: 35819921 Free PMC article.
We therefore suggest that the time is ripe to develop a lexicon of terms for classifying the micromorphology of breast calcifications. METHODS: Calcifications within a wide range of histological sections of breast tissue, both benign and malignant, were image …
We therefore suggest that the time is ripe to develop a lexicon of terms for classifying the micromorphology of breast calcifications …
Radiotherapy-induced oxidative stress and fibrosis in breast cancer are suppressed by vactosertib, a novel, orally bioavailable TGF-beta/ALK5 inhibitor.
Park J, Choi J, Cho I, Sheen YY. Park J, et al. Sci Rep. 2022 Sep 27;12(1):16104. doi: 10.1038/s41598-022-20050-9. Sci Rep. 2022. PMID: 36167880 Free PMC article.
Radio-resistance resulting from radiotherapy-induced fibrosis is a major clinical obstacle in breast cancer treatment because it typically leads to cancer recurrence, treatment failure, and patient death. ...However, combination therapy with vactosertib not only inhibits t …
Radio-resistance resulting from radiotherapy-induced fibrosis is a major clinical obstacle in breast cancer treatment because it typi …
Palpable breast lumps: An age-based approach to evaluation and diagnosis.
Malherbe F, Nel D, Molabe H, Cairncross L, Roodt L. Malherbe F, et al. S Afr Fam Pract (2004). 2022 Sep 23;64(1):e1-e5. doi: 10.4102/safp.v64i1.5571. S Afr Fam Pract (2004). 2022. PMID: 36226953 Free PMC article.
A palpable breast lump is a common presentation of breast disease to a general practitioner. Fortunately, investigation of most of these lumps will lead to a benign diagnosis. It is essential to have a clear and systematic approach when investigating a …
A palpable breast lump is a common presentation of breast disease to a general practitioner. Fortunately, investigation …
Benign or premalignant? Idiopathic granulomatous mastitis later diagnosed as ductal carcinoma breast cancer: Case report and review of literature.
Zangouri V, Niazkar HR, Nasrollahi H, Homapour F, Ranjbar A, Seyyedi MS. Zangouri V, et al. Clin Case Rep. 2022 Sep 12;10(9):e6323. doi: 10.1002/ccr3.6323. eCollection 2022 Sep. Clin Case Rep. 2022. PMID: 36172329 Free PMC article.
Idiopathic granulomatous mastitis (IGM) is a rare benign infectious disease of the breast, commonly presenting with a unilateral breast mass. Since GM's clinical presentation and imaging can be very similar to breast cancer, diagnosing GM can be …
Idiopathic granulomatous mastitis (IGM) is a rare benign infectious disease of the breast, commonly presenting with a u …
Breast microbiome associations with breast tumor characteristics and neoadjuvant chemotherapy: A case-control study.
Li X, Sun X, Zhang A, Pang J, Li Y, Yan M, Xu Z, Yu Y, Yang Z, Chen X, Wang X, Cao XC, Tang NJ. Li X, et al. Front Oncol. 2022 Sep 12;12:926920. doi: 10.3389/fonc.2022.926920. eCollection 2022. Front Oncol. 2022. PMID: 36172155 Free PMC article.
BACKGROUND: Commensal microbiota have been proven to colonize the mammary gland, but whether their composition is altered in patients with breast cancer (BC) remains elusive. This study intends to explore the breast microbiome differences between benign and m …
BACKGROUND: Commensal microbiota have been proven to colonize the mammary gland, but whether their composition is altered in patients with …
The Use of Optical Coherence Tomography for Gross Examination and Sampling of Fixed Breast Specimens: A Pilot Study.
Faragalla H, Davoudi B, Nofech-Moses N, Yucel Y, Jakate K. Faragalla H, et al. Diagnostics (Basel). 2022 Sep 9;12(9):2191. doi: 10.3390/diagnostics12092191. Diagnostics (Basel). 2022. PMID: 36140591 Free PMC article.
Ductal carcinoma in situ can be subtle, and it is made more recognizable by the presence of comedo necrosis and calcifications. OCT features of benign and malignant breast entities were compiled in a granular but user-friendly reference tool. CONCLUSION: OCT images …
Ductal carcinoma in situ can be subtle, and it is made more recognizable by the presence of comedo necrosis and calcifications. OCT features …
Ectopic bronchogenic cyst of liver misdiagnosed as gallbladder diverticulum: A case report.
Dong CJ, Yang RM, Wang QL, Wu QY, Yang DJ, Kong DC, Zhang P. Dong CJ, et al. World J Gastroenterol. 2022 Sep 7;28(33):4920-4925. doi: 10.3748/wjg.v28.i33.4920. World J Gastroenterol. 2022. PMID: 36156928 Free PMC article.
CONCLUSION: Radiologists, hepatobiliary and pancreatic surgeons, gastrointestinal surgeons, urologists, and even neurosurgeons should be aware and consider a possible diagnosis of ectopic bronchogenic cysts, especially when other types of cyst, cystadenoma, and other diseases
CONCLUSION: Radiologists, hepatobiliary and pancreatic surgeons, gastrointestinal surgeons, urologists, and even neurosurgeons should be awa …
Causes of bloody stools in neonates: a case series report.
Lin M, Zhu H, Zhang R, Wang H. Lin M, et al. Transl Pediatr. 2022 Sep;11(9):1438-1444. doi: 10.21037/tp-22-166. Transl Pediatr. 2022. PMID: 36247883 Free PMC article.
Previous studies always focused on one particular disease related to bloody stools in neonates, or the study only involved a small number of cases. ...Survival at hospital discharge was 100%. CONCLUSIONS: Bloody stools in neonates is generally a benign, self-limitin …
Previous studies always focused on one particular disease related to bloody stools in neonates, or the study only involved a small nu …
Drugs That Changed Society: Microtubule-Targeting Agents Belonging to Taxanoids, Macrolides and Non-Ribosomal Peptides.
Christensen SB. Christensen SB. Molecules. 2022 Sep 1;27(17):5648. doi: 10.3390/molecules27175648. Molecules. 2022. PMID: 36080414 Free PMC article. Review.
During a screening performed by the National Cancer Institute in the 1960s, the terpenoid paclitaxel was discovered. Paclitaxel expanded the treatment options for breast, lung, prostate and ovarian cancer. Paclitaxel is only present in minute amounts in the bark of Taxia b …
During a screening performed by the National Cancer Institute in the 1960s, the terpenoid paclitaxel was discovered. Paclitaxel expanded the …
Transient ipsilateral breast edema following COVID-19 vaccination.
McGrath AL, Drotman MB, Dodelzon K. McGrath AL, et al. Clin Imaging. 2022 Sep;89:89-91. doi: 10.1016/j.clinimag.2022.06.006. Epub 2022 Jun 23. Clin Imaging. 2022. PMID: 35772333 Free PMC article.
While ipsilateral lymphadenopathy following COVID-19 vaccination is a relatively common finding on mammography and breast ultrasound transient ipsilateral breast edema is rare with only a few published case reports. Radiologists should be aware of this potential ima …
While ipsilateral lymphadenopathy following COVID-19 vaccination is a relatively common finding on mammography and breast ultrasound …
Reversible Gynecomastia in HIV-Infected Man Treated With Triple Antiretroviral Therapy Containing Efavirenz: A Case Report.
Essafi MA, Elazizi L, Aynaou H, Salhi H, El Ouahabi H. Essafi MA, et al. Cureus. 2022 Aug 14;14(8):e27991. doi: 10.7759/cureus.27991. eCollection 2022 Aug. Cureus. 2022. PMID: 36120227 Free PMC article.
Gynecomastia is benign hypertrophy of male breast glandular tissue, either unilateral or bilateral, secondary to increased estrogen/testosterone ratio (elevated estrogen level, decreased testosterone levels, or both). ...After one year, the patient presented in the …
Gynecomastia is benign hypertrophy of male breast glandular tissue, either unilateral or bilateral, secondary to increased est …
Pseudoangiomatous stromal hyperplasia of the breast: A case report.
Tahmasebi S, Khorsand Rahim Zadeh A, Zangouri V, Akrami M, Ghoddusi Johari M, Talei A. Tahmasebi S, et al. Clin Case Rep. 2022 Aug 9;10(8):e6221. doi: 10.1002/ccr3.6221. eCollection 2022 Aug. Clin Case Rep. 2022. PMID: 35957783 Free PMC article.
Pseudoangiomatous stromal hyperplasia (PASH) is a rare benign breast entity scarcely reported in the medical literature. ...
Pseudoangiomatous stromal hyperplasia (PASH) is a rare benign breast entity scarcely reported in the medical literature. ...
A Comparative Study Between Fine-Needle Aspiration Cytology and Core Needle Biopsy in Diagnosing Clinically Palpable Breast Lumps.
Tripathi K, Yadav R, Maurya SK. Tripathi K, et al. Cureus. 2022 Aug 5;14(8):e27709. doi: 10.7759/cureus.27709. eCollection 2022 Aug. Cureus. 2022. PMID: 36081980 Free PMC article.
Background and objective Most breast diseases present as palpable lumps. The accuracy of their diagnosis can be enhanced by a combination of clinical examination, mammography, fine-needle aspiration cytology (FNAC), and core needle biopsy (CNB) preoperatively. The u …
Background and objective Most breast diseases present as palpable lumps. The accuracy of their diagnosis can be enhanced by a …
A Clinical, Etiological, and Therapeutic Profile of Gynecomastia.
Elazizi L, Essafi MA, Hanane A, Aynaou H, Salhi H, El Ouahabi H. Elazizi L, et al. Cureus. 2022 Aug 4;14(8):e27687. doi: 10.7759/cureus.27687. eCollection 2022 Aug. Cureus. 2022. PMID: 36072183 Free PMC article.
Background and objective Gynecomastia is defined as a benign proliferation of male breast glandular tissue, either unilateral or bilateral, resulting from an imbalance of testosterone and estrogen. ...Regarding treatment, 42% of patients received an etiological trea …
Background and objective Gynecomastia is defined as a benign proliferation of male breast glandular tissue, either unilateral …