Molecular and biological diagnostic tests for monitoring benzimidazole resistance in human soil-transmitted helminths.
Am J Trop Med Hyg. 2013.
PMID: 23458960
Free PMC article.
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Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm.
Lancet. 2006 May 6;367(9521):1521-32. doi: 10.1016/S0140-6736(06)68653-4.
Lancet. 2006.
PMID: 16679166
Review.
The three main soil-transmitted helminth infections, ascariasis, trichuriasis, and hookworm, are common clinical disorders in man. ...The use of these drugs is not limited to treatment of symptomatic soil-transmitted helminth infections, …
The three main soil-transmitted helminth infections, ascariasis, trichuriasis, and hookworm, are common clinical disord …
Is anthelmintic resistance a concern for the control of human soil-transmitted helminths?
Int J Parasitol Drugs Drug Resist. 2011 Oct 14;1(1):14-27. doi: 10.1016/j.ijpddr.2011.09.002. eCollection 2011 Dec.
Int J Parasitol Drugs Drug Resist. 2011.
PMID: 24533260
Free PMC article.
Review.
The major human soil-transmitted helminths (STH), Ascaris lumbricoides, hookworms (Necator americanus and Ancylostoma duodenale) and Trichuris trichiura have a marked impact on human health in many parts of the world. ...In this review we address these issues …
The major human soil-transmitted helminths (STH), Ascaris lumbricoides, hookworms (Necator americanus and Ancylostoma d …
Predicting the risk and speed of drug resistance emerging in soil-transmitted helminths during preventive chemotherapy.
Nat Commun. 2024 Feb 6;15(1):1099. doi: 10.1038/s41467-024-45027-2.
Nat Commun. 2024.
PMID: 38321011
Free PMC article.
Control of soil-transmitted helminths relies heavily on regular large-scale deworming of high-risk groups (e.g., children) with benzimidazole derivatives. Although drug resistance has not yet been documented in human soil-transmitted …
Control of soil-transmitted helminths relies heavily on regular large-scale deworming of high-risk groups (e.g., childr …
Drug Combinations Against Soil-Transmitted Helminth Infections.
Adv Parasitol. 2019;103:91-115. doi: 10.1016/bs.apar.2018.08.002. Epub 2018 Sep 7.
Adv Parasitol. 2019.
PMID: 30878060
Review.
The soil-transmitted helminths (STHs), Ascaris lumbricoides, hookworm and Trichuris trichiura are common in areas with warm and moist climates with little access to adequate water, sanitation, and hygiene affecting the poorest populations. ...The recent succe …
The soil-transmitted helminths (STHs), Ascaris lumbricoides, hookworm and Trichuris trichiura are common in areas with …
[Geohelminths].
Enferm Infecc Microbiol Clin. 2016 Jun-Jul;34(6):384-9. doi: 10.1016/j.eimc.2016.02.002. Epub 2016 Mar 12.
Enferm Infecc Microbiol Clin. 2016.
PMID: 26980233
Spanish.
Millions of people in in rural areas and deprived tropical and subtropical regions are infected by soil-transmitted helminths: Ascaris lumbricoides, Trichuris trichiura, hookworms (Ancylostoma duodenale and Necator americanus), and Strongyloides stercoralis. …
Millions of people in in rural areas and deprived tropical and subtropical regions are infected by soil-transmitted helmint …
Molecular and biological diagnostic tests for monitoring benzimidazole resistance in human soil-transmitted helminths.
Am J Trop Med Hyg. 2013 Jun;88(6):1052-61. doi: 10.4269/ajtmh.12-0484. Epub 2013 Mar 4.
Am J Trop Med Hyg. 2013.
PMID: 23458960
Free PMC article.
In endemic countries with soil-transmitted helminths mass drug administration with albendazole or mebendazole are being implemented as a control strategy. ...Given the concern that resistance could arise in human soil-transmitted helmi …
In endemic countries with soil-transmitted helminths mass drug administration with albendazole or mebendazole are being …
Efficacy of Anthelminthic Drugs and Drug Combinations Against Soil-transmitted Helminths: A Systematic Review and Network Meta-analysis.
Clin Infect Dis. 2019 Jan 1;68(1):96-105. doi: 10.1093/cid/ciy423.
Clin Infect Dis. 2019.
PMID: 29788074
Free article.
BACKGROUND: Periodic mass distribution of benzimidazole anthelminthic drugs is the key strategy to control soil-transmitted helminths (STHs) globally. However, benzimidazoles have low efficacy against Trichuris trichiura, and there are concerns …
BACKGROUND: Periodic mass distribution of benzimidazole anthelminthic drugs is the key strategy to control soil-transmitted …
High Endemicity of Soil-Transmitted Helminths in a Population Frequently Exposed to Albendazole but No Evidence of Antiparasitic Resistance.
Trop Med Infect Dis. 2019 Apr 27;4(2):73. doi: 10.3390/tropicalmed4020073.
Trop Med Infect Dis. 2019.
PMID: 31035610
Free PMC article.
INTRODUCTION: Soil-transmitted helminths (STHs) are gastrointestinal parasites widely distributed in tropical and subtropical areas. Mass drug administration (MDA) of benzimidazoles (BZ) is the most recommended for STH control. These drugs have demonst …
INTRODUCTION: Soil-transmitted helminths (STHs) are gastrointestinal parasites widely distributed in tropical and subtr …
Preventive Chemotherapy in the Fight against Soil-Transmitted Helminthiasis: Achievements and Limitations.
Trends Parasitol. 2018 Jul;34(7):590-602. doi: 10.1016/j.pt.2018.04.008. Epub 2018 May 29.
Trends Parasitol. 2018.
PMID: 29858018
Review.
Soil-transmitted helminths (STHs) are endemic in more than half of the world's countries. ...Two factors might jeopardise the success of PC programs. First, the benzimidazoles possess unsatisfactory efficacy against Trichuris trichiura infections. Seco …
Soil-transmitted helminths (STHs) are endemic in more than half of the world's countries. ...Two factors might jeopardi …
Benzimidazole resistance-associated mutations improve the in silico dimerization of hookworm tubulin: An additional resistance mechanism.
Vet World. 2024 Dec;17(12):2736-2746. doi: 10.14202/vetworld.2024.2736-2746. Epub 2024 Dec 6.
Vet World. 2024.
PMID: 39897360
Free PMC article.
BACKGROUND AND AIM: Mutations in the beta-tubulin genes of helminths confer benzimidazole (BZ) resistance by reducing the drug's binding efficiency to the expressed protein. However, the effects of these resistance-associated mutations on tubulin dimer …
BACKGROUND AND AIM: Mutations in the beta-tubulin genes of helminths confer benzimidazole (BZ) resistance by reducing t …
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