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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1966 9
1967 11
1968 10
1969 13
1970 11
1971 17
1972 18
1973 20
1974 25
1975 34
1976 23
1977 43
1978 28
1979 60
1980 62
1981 56
1982 90
1983 102
1984 66
1985 112
1986 104
1987 110
1988 129
1989 120
1990 126
1991 125
1992 121
1993 134
1994 105
1995 119
1996 152
1997 128
1998 183
1999 134
2000 128
2001 138
2002 119
2003 126
2004 129
2005 120
2006 121
2007 121
2008 107
2009 88
2010 89
2011 112
2012 119
2013 124
2014 120
2015 126
2016 125
2017 108
2018 102
2019 99
2020 89
2021 114
2022 131
2023 122
2024 130
2025 124
2026 36

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Search Results

5,418 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Target attainment of benzylpenicillin in patients with infective endocarditis.
Bock M, Van Hasselt JGC, Fuursted K, Ihlemann N, Gill S, Christiansen U, Bruun NE, Elming H, Povlsen JA, Køber L, Høfsten DE, Fosbøl EL, Pries-Heje MM, Christensen JJ, Rosenvinge FS, Pedersen CT, Helweg-Larsen J, Tønder N, Iversen K, Bundgaard H, Moser C. Bock M, et al. Clin Microbiol Infect. 2025 Aug;31(8):1350-1355. doi: 10.1016/j.cmi.2025.04.025. Epub 2025 Apr 28. Clin Microbiol Infect. 2025. PMID: 40306489 Clinical Trial.
OBJECTIVES: Benzylpenicillin is commonly used to treat infective endocarditis, particularly for streptococcal infections. ...This substudy included patients receiving intravenous benzylpenicillin (3000 mg q6h). Pharmacokinetic measurements were conducted, and a popu …
OBJECTIVES: Benzylpenicillin is commonly used to treat infective endocarditis, particularly for streptococcal infections. ...This sub …
One Dose versus Three Doses of Benzathine Penicillin G in Early Syphilis.
Hook EW 3rd, Dionne JA, Workowski K, McNeil CJ, Taylor SN, Batteiger TA, Dombrowski JC, Mayer KH, Seña AC, Hamill MM, Wiesenfeld HC, Zhu C, Perlowski C, Mejia-Galvis JE, Newman LM. Hook EW 3rd, et al. N Engl J Med. 2025 Sep 4;393(9):869-878. doi: 10.1056/NEJMoa2401802. N Engl J Med. 2025. PMID: 40902161 Free PMC article. Clinical Trial.
BACKGROUND: Controversy persists regarding the appropriate duration of therapy with benzathine penicillin G in persons with early (i.e., primary, secondary, or early latent) syphilis (Treponema pallidum infection). ...CONCLUSIONS: Treatment with one dose of 2.4 mill …
BACKGROUND: Controversy persists regarding the appropriate duration of therapy with benzathine penicillin G in persons with ea …
Effects of early-life antibiotics on the developing infant gut microbiome and resistome: a randomized trial.
Reyman M, van Houten MA, Watson RL, Chu MLJN, Arp K, de Waal WJ, Schiering I, Plötz FB, Willems RJL, van Schaik W, Sanders EAM, Bogaert D. Reyman M, et al. Nat Commun. 2022 Feb 16;13(1):893. doi: 10.1038/s41467-022-28525-z. Nat Commun. 2022. PMID: 35173154 Free PMC article. Clinical Trial.
Here, 147 infants born at 36 weeks of gestational age, requiring broad-spectrum antibiotics for treatment of sEONS in their first week of life were randomized 1:1:1 to receive three commonly prescribed intravenous antibiotic combinations, namely penicillin + gentamicin, c …
Here, 147 infants born at 36 weeks of gestational age, requiring broad-spectrum antibiotics for treatment of sEONS in their first week of l …
Interventions for the prevention of recurrent erysipelas and cellulitis.
Dalal A, Eskin-Schwartz M, Mimouni D, Ray S, Days W, Hodak E, Leibovici L, Paul M. Dalal A, et al. Cochrane Database Syst Rev. 2017 Jun 20;6(6):CD009758. doi: 10.1002/14651858.CD009758.pub2. Cochrane Database Syst Rev. 2017. PMID: 28631307 Free PMC article.
Among the studies assessing antibiotics, one study evaluated oral erythromycin (n = 32) and four studies assessed penicillin (n = 481). Treatment duration varied from six to 18 months, and two studies continued to follow up participants after discontinuation of prophylaxis …
Among the studies assessing antibiotics, one study evaluated oral erythromycin (n = 32) and four studies assessed penicillin (n = 481 …
Different antibiotic treatments for group A streptococcal pharyngitis.
van Driel ML, De Sutter AI, Thorning S, Christiaens T. van Driel ML, et al. Cochrane Database Syst Rev. 2021 Mar 17;3(3):CD004406. doi: 10.1002/14651858.CD004406.pub5. Cochrane Database Syst Rev. 2021. Update in: Cochrane Database Syst Rev. 2023 Nov 15;11:CD004406. doi: 10.1002/14651858.CD004406.pub6. PMID: 33728634 Free PMC article. Updated.
MAIN RESULTS: We included 19 trials reported in 18 publications (5839 randomised participants): six trials compared penicillin with cephalosporins; six compared penicillin with macrolides; three compared penicillin with carbacephem; one compared penicillin …
MAIN RESULTS: We included 19 trials reported in 18 publications (5839 randomised participants): six trials compared penicillin with c …
Oral linezolid compared with benzathine penicillin G for treatment of early syphilis in adults (Trep-AB Study) in Spain: a prospective, open-label, non-inferiority, randomised controlled trial.
Ubals M, Nadal-Baron P, Arando M, Rivero Á, Mendoza A, Descalzo Jorro V, Ouchi D, Pérez-Mañá C, Álvarez M, Alemany A, Hoyos-Mallecot Y, Nunley E, Lieberman NAP, Greninger AL, Galván-Casas C, Suñer C, G-Beiras C, Paredes R, Rodríguez-Gascón A, Canut A, García-Patos V, Farré M, Marks M, Giacani L, Vall-Mayans M, Mitjà O. Ubals M, et al. Lancet Infect Dis. 2024 Apr;24(4):404-416. doi: 10.1016/S1473-3099(23)00683-7. Epub 2024 Jan 8. Lancet Infect Dis. 2024. PMID: 38211601 Free PMC article. Clinical Trial.
BACKGROUND: Management of syphilis, a sexually transmitted infection (STI) with increasing incidence, is challenged by drug shortages, scarcity of randomised trial data, an absence of non-penicillin alternatives for pregnant women with penicillin allergy (other than …
BACKGROUND: Management of syphilis, a sexually transmitted infection (STI) with increasing incidence, is challenged by drug shortages, scarc …
Benzylpenicillin plus an aminoglycoside versus meropenem in neutropenic lymphoma and leukaemia patients with a suspected bacterial infection: a randomized, controlled trial.
Torfoss D, Fladhagen T, Holte H, Brinch L, Schjesvold FH, Fløisand Y, Nyquist E, Dalgaard J, Meyer P, Lehmann AK, Hammerstrøm J, Skjelbakken T, Høiby EA, Sandvik L, Kvaløy S. Torfoss D, et al. Clin Microbiol Infect. 2017 Mar;23(3):179-187. doi: 10.1016/j.cmi.2016.10.019. Epub 2016 Oct 26. Clin Microbiol Infect. 2017. PMID: 27793737 Free article. Clinical Trial.
OBJECTIVES: In Norway, initial treatment of febrile neutropenia (FN) has traditionally been benzylpenicillin plus an aminoglycoside. Internationally, FN is often treated with a broad-spectrum beta-lactam antibiotic. ...CONCLUSION: Clinical success was more common in FN pat …
OBJECTIVES: In Norway, initial treatment of febrile neutropenia (FN) has traditionally been benzylpenicillin plus an aminoglycoside. …
Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers.
Kado JH, Salman S, Henderson R, Hand R, Wyber R, Page-Sharp M, Batty K, Carapetis J, Manning L. Kado JH, et al. J Antimicrob Chemother. 2020 Oct 1;75(10):2951-2959. doi: 10.1093/jac/dkaa282. J Antimicrob Chemother. 2020. PMID: 32696033 Clinical Trial.
METHODS: To compare the pharmacokinetic profile and tolerability of benzathine penicillin G according to different routes of administration, 15 healthy males participated in a randomized crossover study to receive benzathine penicillin G by either SC o …
METHODS: To compare the pharmacokinetic profile and tolerability of benzathine penicillin G according to different routes of a …
Insights Into Treatment Alternatives for Neurosyphilis: Systematic Literature Review and Meta-Analysis.
Callado GY, Pardo I, Gutfreund MC, Deliberato RO, Holubar M, Salinas JL, Marra CM, Perencevich EN, Marra AR. Callado GY, et al. Sex Transm Dis. 2024 Oct 1;51(10):641-647. doi: 10.1097/OLQ.0000000000001983. Epub 2024 Apr 24. Sex Transm Dis. 2024. PMID: 38661311
Our analysis revealed that the efficacy of intravenous (IV) ceftriaxone 2 g daily for 10 days (51 patients) did not appear statistically different compared with IV penicillin G 18 to 24 million units daily for 10 days (185 patients) for neurosyphilis (pooled odds ra …
Our analysis revealed that the efficacy of intravenous (IV) ceftriaxone 2 g daily for 10 days (51 patients) did not appear statistically dif …
Decrease of selective immunoglobulin E response to amoxicillin despite repeated administration of benzylpenicillin and penicillin V.
Fernandez T, Torres MJ, R-Pena R, Fuentes MS, Robles S, Mayorga C, Blanca M. Fernandez T, et al. Clin Exp Allergy. 2005 Dec;35(12):1645-50. doi: 10.1111/j.1365-2222.2005.02378.x. Clin Exp Allergy. 2005. PMID: 16393332 Clinical Trial.
OBJECTIVE: To determine in subjects with selective responses to amoxicillin (AX) and good tolerance to benzylpenicillin (BP) and penicillin V (PV) whether the administration of these compounds induced any change in specificity, measured by either skin or in vitro te …
OBJECTIVE: To determine in subjects with selective responses to amoxicillin (AX) and good tolerance to benzylpenicillin (BP) and p …
5,418 results