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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1927 1
1929 2
1930 1
1932 1
1933 3
1934 1
1940 1
1944 1
1948 1
1949 2
1950 1
1952 3
1953 4
1954 2
1955 1
1956 4
1958 3
1959 5
1960 7
1961 2
1962 10
1963 8
1964 14
1965 9
1966 6
1967 6
1968 5
1969 13
1970 16
1971 11
1972 20
1973 10
1974 11
1975 18
1976 20
1977 31
1978 14
1979 13
1980 8
1981 17
1982 18
1983 20
1984 13
1985 22
1986 37
1987 36
1988 38
1989 44
1990 49
1991 45
1992 64
1993 44
1994 48
1995 43
1996 95
1997 46
1998 64
1999 56
2000 106
2001 76
2002 72
2003 83
2004 87
2005 125
2006 141
2007 158
2008 179
2009 204
2010 274
2011 302
2012 333
2013 313
2014 398
2015 405
2016 436
2017 465
2018 506
2019 503
2020 616
2021 235
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6,355 results
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Page 1
Berberine, an epiphany against cancer.
Ortiz LM, Lombardi P, Tillhon M, Scovassi AI. Ortiz LM, et al. Molecules. 2014 Aug 15;19(8):12349-67. doi: 10.3390/molecules190812349. Molecules. 2014. PMID: 25153862 Free PMC article. Review.
In recent years, berberine has been reported to inhibit cell proliferation and to be cytotoxic towards cancer cells. ...The main properties of berberine and derivatives will be illustrated....
In recent years, berberine has been reported to inhibit cell proliferation and to be cytotoxic towards cancer cells. ...The main prop …
The metabolism of berberine and its contribution to the pharmacological effects.
Wang K, Feng X, Chai L, Cao S, Qiu F. Wang K, et al. Drug Metab Rev. 2017 May;49(2):139-157. doi: 10.1080/03602532.2017.1306544. Epub 2017 Apr 3. Drug Metab Rev. 2017. PMID: 28290706 Review.
Meanwhile, berberine undergoes extensive metabolism after oral administration which results in its extremely low plasma exposure. ...Overall, berberine together with its metabolites formed the material basis of berberine in vivo....
Meanwhile, berberine undergoes extensive metabolism after oral administration which results in its extremely low plasma exposure. ... …
Berberine and Its Role in Chronic Disease.
Cicero AF, Baggioni A. Cicero AF, et al. Adv Exp Med Biol. 2016;928:27-45. doi: 10.1007/978-3-319-41334-1_2. Adv Exp Med Biol. 2016. PMID: 27671811 Review.
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Altogether the available evidences suggest a possible application of berberine use in the management of chronic cardiometabolic disorders....
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Altogether the available evidence
Berberis Vulgaris and Berberine: An Update Review.
Imenshahidi M, Hosseinzadeh H. Imenshahidi M, et al. Phytother Res. 2016 Nov;30(11):1745-1764. doi: 10.1002/ptr.5693. Epub 2016 Aug 16. Phytother Res. 2016. PMID: 27528198 Review.
Berberine is an isoquinoline alkaloid present in several plants, including Coptis sp. and Berberis sp. Berberine is a customary component in Chinese medicine, and is characterized by a diversity of pharmacological effects. ...
Berberine is an isoquinoline alkaloid present in several plants, including Coptis sp. and Berberis sp. Berberine is a customar
Berberine and barberry (Berberis vulgaris): A clinical review.
Imenshahidi M, Hosseinzadeh H. Imenshahidi M, et al. Phytother Res. 2019 Mar;33(3):504-523. doi: 10.1002/ptr.6252. Epub 2019 Jan 13. Phytother Res. 2019. PMID: 30637820 Review.
An extensive search in electronic databases (PubMed, Scopus, Embase, Web of Sciences and Science Direct) was used to identify the clinical trials on B. vulgaris and berberine. Lipid-lowering and insulin-resistance improving actions are the most studied properties of ber
An extensive search in electronic databases (PubMed, Scopus, Embase, Web of Sciences and Science Direct) was used to identify the clinical t …
Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics.
Feng X, Sureda A, Jafari S, Memariani Z, Tewari D, Annunziata G, Barrea L, Hassan STS, Šmejkal K, Malaník M, Sychrová A, Barreca D, Ziberna L, Mahomoodally MF, Zengin G, Xu S, Nabavi SM, Shen AZ. Feng X, et al. Theranostics. 2019 Mar 16;9(7):1923-1951. doi: 10.7150/thno.30787. eCollection 2019. Theranostics. 2019. PMID: 31037148 Free PMC article. Review.
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide, underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is an eminent component of traditional Chinese and Ayurvedic medicine for more than 2000 years. ...
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide, underscoring the urgent necessity to develop new pha …
Pharmacological effects of berberine and its derivatives: a patent update.
Jin Y, Khadka DB, Cho WJ. Jin Y, et al. Expert Opin Ther Pat. 2016;26(2):229-43. doi: 10.1517/13543776.2016.1118060. Epub 2015 Dec 4. Expert Opin Ther Pat. 2016. PMID: 26610159 Review.
AREAS COVERED: This review discusses recent and mostly Chinese patents that report the synthesis of berberine, berberine derivatives and berberine salts, and methods of preparation for formulations (traditional Chinese medicine) containing herbal components r …
AREAS COVERED: This review discusses recent and mostly Chinese patents that report the synthesis of berberine, berberine deriv …
Berberine pharmacology and the gut microbiota: A hidden therapeutic link.
Habtemariam S. Habtemariam S. Pharmacol Res. 2020 May;155:104722. doi: 10.1016/j.phrs.2020.104722. Epub 2020 Feb 24. Pharmacol Res. 2020. PMID: 32105754 Review.
The multifunctional nature of berberine as a therapeutic agent is an attribute of its diverse effects on enzymes, receptors and cell signalling pathways. ...A growing evidence now suggest the role of the gut microbiota, the so-called the hidden organ, as targets for the mu …
The multifunctional nature of berberine as a therapeutic agent is an attribute of its diverse effects on enzymes, receptors and cell …
Current knowledge and pharmacological profile of berberine: An update.
Kumar A, Ekavali, Chopra K, Mukherjee M, Pottabathini R, Dhull DK. Kumar A, et al. Eur J Pharmacol. 2015 Aug 15;761:288-97. doi: 10.1016/j.ejphar.2015.05.068. Epub 2015 Jun 16. Eur J Pharmacol. 2015. PMID: 26092760 Review.
Studies regarding the safety profile, drug interactions and important clinical trials of berberine have also been included. Clinical trials with respect to neurological disorders need to be undertaken to exploit the beneficiary effects of berberine against serious d …
Studies regarding the safety profile, drug interactions and important clinical trials of berberine have also been included. Clinical …
Antiviral activity of berberine.
Warowicka A, Nawrot R, Goździcka-Józefiak A. Warowicka A, et al. Arch Virol. 2020 Sep;165(9):1935-1945. doi: 10.1007/s00705-020-04706-3. Epub 2020 Jun 28. Arch Virol. 2020. PMID: 32594322 Free PMC article. Review.
Plants are a rich source of new antiviral, pharmacologically active agents. The naturally occurring plant alkaloid berberine (BBR) is one of the phytochemicals with a broad range of biological activity, including anticancer, anti-inflammatory and antiviral activity. ...In …
Plants are a rich source of new antiviral, pharmacologically active agents. The naturally occurring plant alkaloid berberine (BBR) is …
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