Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1927 1
1929 2
1930 1
1932 1
1933 3
1934 1
1940 1
1944 1
1948 1
1949 2
1950 1
1952 3
1953 4
1954 2
1955 1
1956 4
1958 3
1959 5
1960 7
1961 2
1962 10
1963 8
1964 14
1965 9
1966 6
1967 6
1968 5
1969 13
1970 16
1971 11
1972 20
1973 10
1974 11
1975 18
1976 20
1977 31
1978 14
1979 13
1980 8
1981 17
1982 18
1983 20
1984 13
1985 22
1986 37
1987 36
1988 38
1989 44
1990 49
1991 45
1992 64
1993 44
1994 49
1995 43
1996 95
1997 46
1998 64
1999 56
2000 106
2001 76
2002 72
2003 83
2004 87
2005 125
2006 141
2007 158
2008 179
2009 204
2010 274
2011 302
2012 333
2013 313
2014 399
2015 407
2016 436
2017 466
2018 513
2019 523
2020 652
2021 717
2022 706
2023 637
2024 799
2025 333

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

9,014 results

Results by year

Filters applied: . Clear all
Page 1
The metabolism of berberine and its contribution to the pharmacological effects.
Wang K, Feng X, Chai L, Cao S, Qiu F. Wang K, et al. Drug Metab Rev. 2017 May;49(2):139-157. doi: 10.1080/03602532.2017.1306544. Epub 2017 Apr 3. Drug Metab Rev. 2017. PMID: 28290706 Review.
Meanwhile, berberine undergoes extensive metabolism after oral administration which results in its extremely low plasma exposure. ...Overall, berberine together with its metabolites formed the material basis of berberine in vivo....
Meanwhile, berberine undergoes extensive metabolism after oral administration which results in its extremely low plasma exposure. ... …
Anticancer Effects and Mechanisms of Berberine from Medicinal Herbs: An Update Review.
Xiong RG, Huang SY, Wu SX, Zhou DD, Yang ZJ, Saimaiti A, Zhao CN, Shang A, Zhang YJ, Gan RY, Li HB. Xiong RG, et al. Molecules. 2022 Jul 15;27(14):4523. doi: 10.3390/molecules27144523. Molecules. 2022. PMID: 35889396 Free PMC article. Review.
This paper summarizes effectiveness and mechanisms of berberine on different cancers and highlights the mechanisms of action. In addition, the nanotechnologies to improve bioavailability of berberine are included. Moreover, the side effects of berberine are a …
This paper summarizes effectiveness and mechanisms of berberine on different cancers and highlights the mechanisms of action. In addi …
Berberine and Its Role in Chronic Disease.
Cicero AF, Baggioni A. Cicero AF, et al. Adv Exp Med Biol. 2016;928:27-45. doi: 10.1007/978-3-319-41334-1_2. Adv Exp Med Biol. 2016. PMID: 27671811 Review.
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Altogether the available evidences suggest a possible application of berberine use in the management of chronic cardiometabolic disorders....
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Altogether the available evidence
Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics.
Feng X, Sureda A, Jafari S, Memariani Z, Tewari D, Annunziata G, Barrea L, Hassan STS, Šmejkal K, Malaník M, Sychrová A, Barreca D, Ziberna L, Mahomoodally MF, Zengin G, Xu S, Nabavi SM, Shen AZ. Feng X, et al. Theranostics. 2019 Mar 16;9(7):1923-1951. doi: 10.7150/thno.30787. eCollection 2019. Theranostics. 2019. PMID: 31037148 Free PMC article. Review.
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide, underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is an eminent component of traditional Chinese and Ayurvedic medicine for more than 2000 years. ...
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide, underscoring the urgent necessity to develop new pha …
Inhibition of inflammation by berberine: Molecular mechanism and network pharmacology analysis.
Wang K, Yin J, Chen J, Ma J, Si H, Xia D. Wang K, et al. Phytomedicine. 2024 Jun;128:155258. doi: 10.1016/j.phymed.2023.155258. Epub 2024 Jan 11. Phytomedicine. 2024. PMID: 38522318
Furthermore, it delves into a deeper understanding of berberine's effectiveness by integrating network pharmacology and molecular docking techniques in the context of treating inflammatory diseases. It provides guidance and reference for berberine's su …
Furthermore, it delves into a deeper understanding of berberine's effectiveness by integrating network pharmacology and molecu …
Berberine pharmacology and the gut microbiota: A hidden therapeutic link.
Habtemariam S. Habtemariam S. Pharmacol Res. 2020 May;155:104722. doi: 10.1016/j.phrs.2020.104722. Epub 2020 Feb 24. Pharmacol Res. 2020. PMID: 32105754 Review.
The multifunctional nature of berberine as a therapeutic agent is an attribute of its diverse effects on enzymes, receptors and cell signalling pathways. ...A growing evidence now suggest the role of the gut microbiota, the so-called the hidden organ, as targets for the mu …
The multifunctional nature of berberine as a therapeutic agent is an attribute of its diverse effects on enzymes, receptors and cell …
Berberine as a Potential Anticancer Agent: A Comprehensive Review.
Rauf A, Abu-Izneid T, Khalil AA, Imran M, Shah ZA, Emran TB, Mitra S, Khan Z, Alhumaydhi FA, Aljohani ASM, Khan I, Rahman MM, Jeandet P, Gondal TA. Rauf A, et al. Molecules. 2021 Dec 4;26(23):7368. doi: 10.3390/molecules26237368. Molecules. 2021. PMID: 34885950 Free PMC article. Review.
Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. ...Despite its significance as a potentially promising drug candidate, there are currentl
Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to
Berberine: Pharmacological Features in Health, Disease and Aging.
Gasmi A, Asghar F, Zafar S, Oliinyk P, Khavrona O, Lysiuk R, Peana M, Piscopo S, Antonyak H, Pen JJ, Lozynska I, Noor S, Lenchyk L, Muhammad A, Vladimirova I, Dub N, Antoniv O, Tsal O, Upyr T, Bjørklund G. Gasmi A, et al. Curr Med Chem. 2024;31(10):1214-1234. doi: 10.2174/0929867330666230207112539. Curr Med Chem. 2024. PMID: 36748808 Review.
BACKGROUND: Berberine is the main active compound of different herbs and is defined as an isoquinoline quaternary botanical alkaloid found in barks and roots of numerous plants. ...Berberine exhibits neuroprotective properties in various neurodegenerative and neurop …
BACKGROUND: Berberine is the main active compound of different herbs and is defined as an isoquinoline quaternary botanical alkaloid …
Berberine in Non-Alcoholic Fatty Liver Disease-A Review.
Koperska A, Wesołek A, Moszak M, Szulińska M. Koperska A, et al. Nutrients. 2022 Aug 23;14(17):3459. doi: 10.3390/nu14173459. Nutrients. 2022. PMID: 36079717 Free PMC article. Review.
Multiple bioactive compounds have been proposed to treat NAFLD. One of the most promising is Berberine (BBR). Its pleiotropic effect positively impacts various cardiometabolic aspects. ...
Multiple bioactive compounds have been proposed to treat NAFLD. One of the most promising is Berberine (BBR). Its pleiotropic effect …
Effects of Berberine against Pancreatitis and Pancreatic Cancer.
Vlavcheski F, O'Neill EJ, Gagacev F, Tsiani E. Vlavcheski F, et al. Molecules. 2022 Dec 6;27(23):8630. doi: 10.3390/molecules27238630. Molecules. 2022. PMID: 36500723 Free PMC article. Review.
Inflammation and fibrosis caused by chronic pancreatitis exacerbate malignant transformation and significantly increase the risk of developing pancreatic cancer, the world's most aggressive cancer with a 5-year survival rate less than 10%. Berberine (BBR) is a naturally oc …
Inflammation and fibrosis caused by chronic pancreatitis exacerbate malignant transformation and significantly increase the risk of developi …
9,014 results