Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1927 1
1929 2
1930 1
1932 1
1933 3
1934 1
1940 1
1944 1
1948 1
1949 2
1950 1
1952 3
1953 4
1954 2
1955 1
1956 4
1958 3
1959 5
1960 7
1961 2
1962 10
1963 8
1964 14
1965 9
1966 6
1967 6
1968 5
1969 13
1970 16
1971 11
1972 20
1973 10
1974 11
1975 18
1976 20
1977 31
1978 14
1979 13
1980 8
1981 17
1982 18
1983 20
1984 13
1985 22
1986 37
1987 36
1988 38
1989 44
1990 49
1991 45
1992 64
1993 44
1994 49
1995 43
1996 95
1997 46
1998 64
1999 56
2000 106
2001 76
2002 72
2003 83
2004 87
2005 125
2006 141
2007 158
2008 179
2009 204
2010 274
2011 302
2012 333
2013 313
2014 399
2015 407
2016 436
2017 466
2018 513
2019 523
2020 652
2021 718
2022 726
2023 682
2024 796
2025 944
2026 778
2027 3

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

10,327 results

Results by year

Filters applied: . Clear all
Page 1
Biological properties and clinical applications of berberine.
Song D, Hao J, Fan D. Song D, et al. Front Med. 2020 Oct;14(5):564-582. doi: 10.1007/s11684-019-0724-6. Epub 2020 Apr 25. Front Med. 2020. PMID: 32335802 Review.
Berberine also inhibits the proliferation of various types of cancer cells and impedes invasion and metastasis. ...Berberine shows potent neuroprotective effects, including antioxidative, antiapoptotic, and anti-ischemic. ...
Berberine also inhibits the proliferation of various types of cancer cells and impedes invasion and metastasis. ...Berberine s …
Berberine and Its Role in Chronic Disease.
Cicero AF, Baggioni A. Cicero AF, et al. Adv Exp Med Biol. 2016;928:27-45. doi: 10.1007/978-3-319-41334-1_2. Adv Exp Med Biol. 2016. PMID: 27671811 Review.
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Altogether the available evidences suggest a possible application of berberine use in the management of chronic cardiometabolic disorders....
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Altogether the available evidence …
The metabolism of berberine and its contribution to the pharmacological effects.
Wang K, Feng X, Chai L, Cao S, Qiu F. Wang K, et al. Drug Metab Rev. 2017 May;49(2):139-157. doi: 10.1080/03602532.2017.1306544. Epub 2017 Apr 3. Drug Metab Rev. 2017. PMID: 28290706 Review.
Meanwhile, berberine undergoes extensive metabolism after oral administration which results in its extremely low plasma exposure. ...Overall, berberine together with its metabolites formed the material basis of berberine in vivo....
Meanwhile, berberine undergoes extensive metabolism after oral administration which results in its extremely low plasma exposure. ... …
Inhibition of inflammation by berberine: Molecular mechanism and network pharmacology analysis.
Wang K, Yin J, Chen J, Ma J, Si H, Xia D. Wang K, et al. Phytomedicine. 2024 Jun;128:155258. doi: 10.1016/j.phymed.2023.155258. Epub 2024 Jan 11. Phytomedicine. 2024. PMID: 38522318
Furthermore, it delves into a deeper understanding of berberine's effectiveness by integrating network pharmacology and molecular docking techniques in the context of treating inflammatory diseases. It provides guidance and reference for berberine's su …
Furthermore, it delves into a deeper understanding of berberine's effectiveness by integrating network pharmacology and molecu …
Berberine pharmacology and the gut microbiota: A hidden therapeutic link.
Habtemariam S. Habtemariam S. Pharmacol Res. 2020 May;155:104722. doi: 10.1016/j.phrs.2020.104722. Epub 2020 Feb 24. Pharmacol Res. 2020. PMID: 32105754 Review.
The multifunctional nature of berberine as a therapeutic agent is an attribute of its diverse effects on enzymes, receptors and cell signalling pathways. ...A growing evidence now suggest the role of the gut microbiota, the so-called the hidden organ, as targets for the mu …
The multifunctional nature of berberine as a therapeutic agent is an attribute of its diverse effects on enzymes, receptors and cell …
Multiple target and regulatory pathways of berberine.
Zhou W, Asif A, Situ C, Wang J, Hao H. Zhou W, et al. Phytomedicine. 2025 Oct;146:157030. doi: 10.1016/j.phymed.2025.157030. Epub 2025 Jul 11. Phytomedicine. 2025. PMID: 40763599 Review.
It also impacts gut flora, offering new treatment avenues for gastrointestinal diseases, diabetes, and related renal disorders. Despite its clinical efficacy, berberine's low oral bioavailability and the complexity of its mechanisms and safety profile highlight the …
It also impacts gut flora, offering new treatment avenues for gastrointestinal diseases, diabetes, and related renal disorders. Despite its …
Coptidis rhizoma and berberine as anti-cancer drugs: A 10-year updates and future perspectives.
Chen G, Zhang C, Zou J, Zhou Z, Zhang J, Yan Y, Liang Y, Tang G, Chen G, Xu X, Wang N, Feng Y. Chen G, et al. Pharmacol Res. 2025 Jun;216:107742. doi: 10.1016/j.phrs.2025.107742. Epub 2025 Apr 19. Pharmacol Res. 2025. PMID: 40258505 Free article. Review.
This paper offers an exhaustive overview of the cancer-fighting characteristics of Coptidis Rhizoma and berberine, while also exploring recent developments in nanotechnology aimed at enhancing the bioavailability of berberine. Furthermore, the side effects and safet …
This paper offers an exhaustive overview of the cancer-fighting characteristics of Coptidis Rhizoma and berberine, while also explori …
Berberine improves ovulation and endometrial receptivity in polycystic ovary syndrome.
Wang Z, Nie K, Su H, Tang Y, Wang H, Xu X, Dong H. Wang Z, et al. Phytomedicine. 2021 Oct;91:153654. doi: 10.1016/j.phymed.2021.153654. Epub 2021 Jul 12. Phytomedicine. 2021. PMID: 34333328 Free article.
Then they was divided into model (Mod) group, low-dose of berberine (BL) group, high-dose of berberine (BH) group and metformin (Met) group as well as a control (Con) group was established. ...These changes could be reversed by high-dose of berberine interven …
Then they was divided into model (Mod) group, low-dose of berberine (BL) group, high-dose of berberine (BH) group and metformi …
The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review.
Nie Q, Li M, Huang C, Yuan Y, Liang Q, Ma X, Qiu T, Li J. Nie Q, et al. J Transl Med. 2024 Mar 1;22(1):225. doi: 10.1186/s12967-024-05011-2. J Transl Med. 2024. PMID: 38429794 Free PMC article.
Importantly, Berberine exhibited a favorable safety profile, with only mild gastrointestinal adverse events reported. CONCLUSION: This meta-analysis demonstrates berberine's efficacy in improving liver enzymes, lipid profile, and insulin sensitivity in NAFLD …
Importantly, Berberine exhibited a favorable safety profile, with only mild gastrointestinal adverse events reported. CONCLUSION: Thi …
Berberine modulates ovarian cancer autophagy and glycolysis through the LINC01123/P65/MAPK10 signaling axis.
Yan X, Yuan C, Wang Z, Xu Z, Wu Z, Wang M, Xu M, Wang Z, Sun Y. Yan X, et al. Phytomedicine. 2024 Dec;135:156121. doi: 10.1016/j.phymed.2024.156121. Epub 2024 Oct 5. Phytomedicine. 2024. PMID: 39395322
These findings were further validated in animal models. CONCLUSION: Our study highlights berberine's dual benefits of anti-inflammatory effects and inhibition of ovarian cancer proliferation and metastasis by modulating autophagy and glycolysis levels. Mechanistical …
These findings were further validated in animal models. CONCLUSION: Our study highlights berberine's dual benefits of anti-inf …
10,327 results
You have reached the last available page of results. Please see the User Guide for more information.