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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1927 1
1929 2
1930 1
1932 1
1933 3
1934 1
1940 1
1944 1
1948 1
1949 2
1950 1
1952 3
1953 4
1954 2
1955 1
1956 4
1958 3
1959 5
1960 7
1961 2
1962 10
1963 8
1964 14
1965 9
1966 6
1967 6
1968 5
1969 13
1970 16
1971 11
1972 20
1973 10
1974 11
1975 18
1976 20
1977 31
1978 14
1979 13
1980 8
1981 17
1982 18
1983 20
1984 13
1985 22
1986 37
1987 36
1988 38
1989 44
1990 49
1991 45
1992 64
1993 44
1994 49
1995 43
1996 95
1997 46
1998 64
1999 56
2000 106
2001 76
2002 72
2003 83
2004 87
2005 125
2006 141
2007 158
2008 179
2009 204
2010 274
2011 302
2012 333
2013 313
2014 399
2015 407
2016 436
2017 466
2018 513
2019 523
2020 652
2021 718
2022 726
2023 682
2024 794
2025 943
2026 220

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9,789 results

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Page 1
Biological properties and clinical applications of berberine.
Song D, Hao J, Fan D. Song D, et al. Front Med. 2020 Oct;14(5):564-582. doi: 10.1007/s11684-019-0724-6. Epub 2020 Apr 25. Front Med. 2020. PMID: 32335802 Review.
Berberine also inhibits the proliferation of various types of cancer cells and impedes invasion and metastasis. ...Berberine shows potent neuroprotective effects, including antioxidative, antiapoptotic, and anti-ischemic. ...
Berberine also inhibits the proliferation of various types of cancer cells and impedes invasion and metastasis. ...Berberine s …
The effect of Berberine on weight loss in order to prevent obesity: A systematic review.
Ilyas Z, Perna S, Al-Thawadi S, Alalwan TA, Riva A, Petrangolini G, Gasparri C, Infantino V, Peroni G, Rondanelli M. Ilyas Z, et al. Biomed Pharmacother. 2020 Jul;127:110137. doi: 10.1016/j.biopha.2020.110137. Epub 2020 Apr 27. Biomed Pharmacother. 2020. PMID: 32353823 Free article.
As a result of this review, we summarized the effects of Berberine in different models and the related mechanism of actions. In preclinical models, Berberine demonstrates that it affects gut microbiota by reducing diversity of microbes starting at a dosage of 100 mg …
As a result of this review, we summarized the effects of Berberine in different models and the related mechanism of actions. In precl …
The metabolism of berberine and its contribution to the pharmacological effects.
Wang K, Feng X, Chai L, Cao S, Qiu F. Wang K, et al. Drug Metab Rev. 2017 May;49(2):139-157. doi: 10.1080/03602532.2017.1306544. Epub 2017 Apr 3. Drug Metab Rev. 2017. PMID: 28290706 Review.
Meanwhile, berberine undergoes extensive metabolism after oral administration which results in its extremely low plasma exposure. ...Overall, berberine together with its metabolites formed the material basis of berberine in vivo....
Meanwhile, berberine undergoes extensive metabolism after oral administration which results in its extremely low plasma exposure. ... …
Inhibition of inflammation by berberine: Molecular mechanism and network pharmacology analysis.
Wang K, Yin J, Chen J, Ma J, Si H, Xia D. Wang K, et al. Phytomedicine. 2024 Jun;128:155258. doi: 10.1016/j.phymed.2023.155258. Epub 2024 Jan 11. Phytomedicine. 2024. PMID: 38522318
Furthermore, it delves into a deeper understanding of berberine's effectiveness by integrating network pharmacology and molecular docking techniques in the context of treating inflammatory diseases. It provides guidance and reference for berberine's su …
Furthermore, it delves into a deeper understanding of berberine's effectiveness by integrating network pharmacology and molecu …
Anticancer Effects and Mechanisms of Berberine from Medicinal Herbs: An Update Review.
Xiong RG, Huang SY, Wu SX, Zhou DD, Yang ZJ, Saimaiti A, Zhao CN, Shang A, Zhang YJ, Gan RY, Li HB. Xiong RG, et al. Molecules. 2022 Jul 15;27(14):4523. doi: 10.3390/molecules27144523. Molecules. 2022. PMID: 35889396 Free PMC article. Review.
This paper summarizes effectiveness and mechanisms of berberine on different cancers and highlights the mechanisms of action. In addition, the nanotechnologies to improve bioavailability of berberine are included. Moreover, the side effects of berberine are a …
This paper summarizes effectiveness and mechanisms of berberine on different cancers and highlights the mechanisms of action. In addi …
Biological Activity of Berberine-A Summary Update.
Och A, Podgórski R, Nowak R. Och A, et al. Toxins (Basel). 2020 Nov 12;12(11):713. doi: 10.3390/toxins12110713. Toxins (Basel). 2020. PMID: 33198257 Free PMC article. Review.
Berberine is a plant metabolite belonging to the group of isoquinoline alkaloids with strong biological and pharmacological activity. ...Therefore, the growing number of papers on berberine demands summarizing the knowledge and research trends. The efficacy of be …
Berberine is a plant metabolite belonging to the group of isoquinoline alkaloids with strong biological and pharmacological activity. …
Berberine and Its Role in Chronic Disease.
Cicero AF, Baggioni A. Cicero AF, et al. Adv Exp Med Biol. 2016;928:27-45. doi: 10.1007/978-3-319-41334-1_2. Adv Exp Med Biol. 2016. PMID: 27671811 Review.
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Altogether the available evidences suggest a possible application of berberine use in the management of chronic cardiometabolic disorders....
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Altogether the available evidence …
Berberine and barberry (Berberis vulgaris): A clinical review.
Imenshahidi M, Hosseinzadeh H. Imenshahidi M, et al. Phytother Res. 2019 Mar;33(3):504-523. doi: 10.1002/ptr.6252. Epub 2019 Jan 13. Phytother Res. 2019. PMID: 30637820 Review.
Here, we investigated the clinical uses of berberine and B. vulgaris in the treatment of different diseases in humans. An extensive search in electronic databases (PubMed, Scopus, Embase, Web of Sciences and Science Direct) was used to identify the clinical trials on B. vu …
Here, we investigated the clinical uses of berberine and B. vulgaris in the treatment of different diseases in humans. An extensive s …
Berberine pharmacology and the gut microbiota: A hidden therapeutic link.
Habtemariam S. Habtemariam S. Pharmacol Res. 2020 May;155:104722. doi: 10.1016/j.phrs.2020.104722. Epub 2020 Feb 24. Pharmacol Res. 2020. PMID: 32105754 Review.
The multifunctional nature of berberine as a therapeutic agent is an attribute of its diverse effects on enzymes, receptors and cell signalling pathways. ...A growing evidence now suggest the role of the gut microbiota, the so-called the hidden organ, as targets for the mu …
The multifunctional nature of berberine as a therapeutic agent is an attribute of its diverse effects on enzymes, receptors and cell …
Berberine: Pharmacological Features in Health, Disease and Aging.
Gasmi A, Asghar F, Zafar S, Oliinyk P, Khavrona O, Lysiuk R, Peana M, Piscopo S, Antonyak H, Pen JJ, Lozynska I, Noor S, Lenchyk L, Muhammad A, Vladimirova I, Dub N, Antoniv O, Tsal O, Upyr T, Bjørklund G. Gasmi A, et al. Curr Med Chem. 2024;31(10):1214-1234. doi: 10.2174/0929867330666230207112539. Curr Med Chem. 2024. PMID: 36748808 Review.
BACKGROUND: Berberine is the main active compound of different herbs and is defined as an isoquinoline quaternary botanical alkaloid found in barks and roots of numerous plants. ...Berberine exhibits neuroprotective properties in various neurodegenerative and neurop …
BACKGROUND: Berberine is the main active compound of different herbs and is defined as an isoquinoline quaternary botanical alkaloid …
9,789 results