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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1927 1
1929 2
1930 1
1932 1
1933 3
1934 1
1940 1
1944 1
1948 1
1949 2
1950 1
1952 3
1953 4
1954 2
1955 1
1956 4
1958 3
1959 5
1960 7
1961 2
1962 10
1963 8
1964 14
1965 9
1966 6
1967 6
1968 5
1969 13
1970 16
1971 11
1972 20
1973 10
1974 11
1975 18
1976 20
1977 31
1978 14
1979 13
1980 8
1981 17
1982 18
1983 20
1984 13
1985 22
1986 37
1987 36
1988 38
1989 44
1990 49
1991 45
1992 64
1993 44
1994 49
1995 43
1996 95
1997 46
1998 64
1999 56
2000 106
2001 76
2002 72
2003 83
2004 87
2005 125
2006 141
2007 158
2008 179
2009 204
2010 274
2011 302
2012 333
2013 313
2014 399
2015 407
2016 436
2017 466
2018 513
2019 523
2020 652
2021 719
2022 705
2023 640
2024 317

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8,281 results

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Page 1
Biological properties and clinical applications of berberine.
Song D, Hao J, Fan D. Song D, et al. Front Med. 2020 Oct;14(5):564-582. doi: 10.1007/s11684-019-0724-6. Epub 2020 Apr 25. Front Med. 2020. PMID: 32335802 Review.
Recent evidence has confirmed that berberine improves the efficacy and safety of chemoradiotherapies. ...Berberine shows potent neuroprotective effects, including antioxidative, antiapoptotic, and anti-ischemic. ...
Recent evidence has confirmed that berberine improves the efficacy and safety of chemoradiotherapies. ...Berberine shows poten …
The metabolism of berberine and its contribution to the pharmacological effects.
Wang K, Feng X, Chai L, Cao S, Qiu F. Wang K, et al. Drug Metab Rev. 2017 May;49(2):139-157. doi: 10.1080/03602532.2017.1306544. Epub 2017 Apr 3. Drug Metab Rev. 2017. PMID: 28290706 Review.
Meanwhile, berberine undergoes extensive metabolism after oral administration which results in its extremely low plasma exposure. ...Overall, berberine together with its metabolites formed the material basis of berberine in vivo....
Meanwhile, berberine undergoes extensive metabolism after oral administration which results in its extremely low plasma exposure. ... …
Berberine and Its Role in Chronic Disease.
Cicero AF, Baggioni A. Cicero AF, et al. Adv Exp Med Biol. 2016;928:27-45. doi: 10.1007/978-3-319-41334-1_2. Adv Exp Med Biol. 2016. PMID: 27671811 Review.
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Altogether the available evidences suggest a possible application of berberine use in the management of chronic cardiometabolic disorders....
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. ...Altogether the available evidence
Berberine, an epiphany against cancer.
Ortiz LM, Lombardi P, Tillhon M, Scovassi AI. Ortiz LM, et al. Molecules. 2014 Aug 15;19(8):12349-67. doi: 10.3390/molecules190812349. Molecules. 2014. PMID: 25153862 Free PMC article. Review.
In recent years, berberine has been reported to inhibit cell proliferation and to be cytotoxic towards cancer cells. ...The main properties of berberine and derivatives will be illustrated....
In recent years, berberine has been reported to inhibit cell proliferation and to be cytotoxic towards cancer cells. ...The main prop …
Berberine pharmacology and the gut microbiota: A hidden therapeutic link.
Habtemariam S. Habtemariam S. Pharmacol Res. 2020 May;155:104722. doi: 10.1016/j.phrs.2020.104722. Epub 2020 Feb 24. Pharmacol Res. 2020. PMID: 32105754 Review.
The multifunctional nature of berberine as a therapeutic agent is an attribute of its diverse effects on enzymes, receptors and cell signalling pathways. ...A growing evidence now suggest the role of the gut microbiota, the so-called the hidden organ, as targets for the mu …
The multifunctional nature of berberine as a therapeutic agent is an attribute of its diverse effects on enzymes, receptors and cell …
Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics.
Feng X, Sureda A, Jafari S, Memariani Z, Tewari D, Annunziata G, Barrea L, Hassan STS, Šmejkal K, Malaník M, Sychrová A, Barreca D, Ziberna L, Mahomoodally MF, Zengin G, Xu S, Nabavi SM, Shen AZ. Feng X, et al. Theranostics. 2019 Mar 16;9(7):1923-1951. doi: 10.7150/thno.30787. eCollection 2019. Theranostics. 2019. PMID: 31037148 Free PMC article. Review.
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide, underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is an eminent component of traditional Chinese and Ayurvedic medicine for more than 2000 years. ...
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide, underscoring the urgent necessity to develop new pha …
Anticancer Effects and Mechanisms of Berberine from Medicinal Herbs: An Update Review.
Xiong RG, Huang SY, Wu SX, Zhou DD, Yang ZJ, Saimaiti A, Zhao CN, Shang A, Zhang YJ, Gan RY, Li HB. Xiong RG, et al. Molecules. 2022 Jul 15;27(14):4523. doi: 10.3390/molecules27144523. Molecules. 2022. PMID: 35889396 Free PMC article. Review.
In addition, the nanotechnologies to improve bioavailability of berberine are included. Moreover, the side effects of berberine are also discussed. This paper is helpful for the prevention and treatment of cancers using berberine....
In addition, the nanotechnologies to improve bioavailability of berberine are included. Moreover, the side effects of berberine
Berberine as a Potential Anticancer Agent: A Comprehensive Review.
Rauf A, Abu-Izneid T, Khalil AA, Imran M, Shah ZA, Emran TB, Mitra S, Khan Z, Alhumaydhi FA, Aljohani ASM, Khan I, Rahman MM, Jeandet P, Gondal TA. Rauf A, et al. Molecules. 2021 Dec 4;26(23):7368. doi: 10.3390/molecules26237368. Molecules. 2021. PMID: 34885950 Free PMC article. Review.
Berberine (BBR), a potential bioactive agent, has remarkable health benefits. ...Despite its significance as a potentially promising drug candidate, there are currently no pure berberine preparations approved to treat specific ailments. Hence, this review highlights
Berberine (BBR), a potential bioactive agent, has remarkable health benefits. ...Despite its significance as a potentially promising
Berberine in Non-Alcoholic Fatty Liver Disease-A Review.
Koperska A, Wesołek A, Moszak M, Szulińska M. Koperska A, et al. Nutrients. 2022 Aug 23;14(17):3459. doi: 10.3390/nu14173459. Nutrients. 2022. PMID: 36079717 Free PMC article. Review.
Multiple bioactive compounds have been proposed to treat NAFLD. One of the most promising is Berberine (BBR). Its pleiotropic effect positively impacts various cardiometabolic aspects. ...
Multiple bioactive compounds have been proposed to treat NAFLD. One of the most promising is Berberine (BBR). Its pleiotropic effect …
Effects of Berberine against Pancreatitis and Pancreatic Cancer.
Vlavcheski F, O'Neill EJ, Gagacev F, Tsiani E. Vlavcheski F, et al. Molecules. 2022 Dec 6;27(23):8630. doi: 10.3390/molecules27238630. Molecules. 2022. PMID: 36500723 Free PMC article. Review.
Inflammation and fibrosis caused by chronic pancreatitis exacerbate malignant transformation and significantly increase the risk of developing pancreatic cancer, the world's most aggressive cancer with a 5-year survival rate less than 10%. Berberine (BBR) is a naturally oc …
Inflammation and fibrosis caused by chronic pancreatitis exacerbate malignant transformation and significantly increase the risk of developi …
8,281 results