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219 results

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Filters applied: Clinical Trial, Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Efficacy of berberine in patients with type 2 diabetes mellitus.
Yin J, Xing H, Ye J. Yin J, et al. Metabolism. 2008 May;57(5):712-7. doi: 10.1016/j.metabol.2008.01.013. Metabolism. 2008. PMID: 18442638 Free PMC article. Clinical Trial.
Berberine has been shown to regulate glucose and lipid metabolism in vitro and in vivo. ...In study B, 48 adults with poorly controlled type 2 diabetes mellitus were treated supplemented with berberine in a 3-month trial. Berberine acted by lowering fasting b …
Berberine has been shown to regulate glucose and lipid metabolism in vitro and in vivo. ...In study B, 48 adults with poorly controll …
Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study).
Zhang Y, Gu Y, Ren H, Wang S, Zhong H, Zhao X, Ma J, Gu X, Xue Y, Huang S, Yang J, Chen L, Chen G, Qu S, Liang J, Qin L, Huang Q, Peng Y, Li Q, Wang X, Kong P, Hou G, Gao M, Shi Z, Li X, Qiu Y, Zou Y, Yang H, Wang J, Xu G, Lai S, Li J, Ning G, Wang W. Zhang Y, et al. Nat Commun. 2020 Oct 6;11(1):5015. doi: 10.1038/s41467-020-18414-8. Nat Commun. 2020. PMID: 33024120 Free PMC article. Clinical Trial.
Measures altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, merit metabolic homoeostasis. We hence conducted a randomized, double-blind, placebo-controlled trial with newly diagnosed T2D patients from 20 centres in China. ...
Measures altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, merit metabolic homoeosta …
The Effect of Berberine on Metabolic Profiles in Type 2 Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Guo J, Chen H, Zhang X, Lou W, Zhang P, Qiu Y, Zhang C, Wang Y, Liu WJ. Guo J, et al. Oxid Med Cell Longev. 2021 Dec 15;2021:2074610. doi: 10.1155/2021/2074610. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 34956436 Free PMC article.
To determine the potential advantages of berberine for diabetic care, we conducted this systematic review and meta-analysis to examine the efficacy and safety of berberine in the treatment of patients with type 2 DM. ...In the future, this may be used to guide targe …
To determine the potential advantages of berberine for diabetic care, we conducted this systematic review and meta-analysis to examin …
The effect of berberine supplementation on obesity parameters, inflammation and liver function enzymes: A systematic review and meta-analysis of randomized controlled trials.
Asbaghi O, Ghanbari N, Shekari M, Reiner Ž, Amirani E, Hallajzadeh J, Mirsafaei L, Asemi Z. Asbaghi O, et al. Clin Nutr ESPEN. 2020 Aug;38:43-49. doi: 10.1016/j.clnesp.2020.04.010. Epub 2020 May 6. Clin Nutr ESPEN. 2020. PMID: 32690176
INTRODUCTION: So far, no study has summarized the findings on the effects of berberine intake on anthropometric parameters, C-reactive protein (CRP) and liver enzymes. ...Berberine administration had no significant effect on ALT and AST levels....
INTRODUCTION: So far, no study has summarized the findings on the effects of berberine intake on anthropometric parameters, C-reactiv …
Protective effect of berberine in diabetic nephropathy: A systematic review and meta-analysis revealing the mechanism of action.
Hu S, Wang J, Liu E, Zhang X, Xiang J, Li W, Wei P, Zeng J, Zhang Y, Ma X. Hu S, et al. Pharmacol Res. 2022 Nov;185:106481. doi: 10.1016/j.phrs.2022.106481. Epub 2022 Oct 3. Pharmacol Res. 2022. PMID: 36195307
Coptis Chinensis Franch is widely used in the treatment of diabetes, and berberine is the primary bioactive component in it. Evidence from previous studies has shown that berberine supplementation is effective for treating diabetic nephropathy (DN) in animal models. …
Coptis Chinensis Franch is widely used in the treatment of diabetes, and berberine is the primary bioactive component in it. Evidence …
Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis.
Zhao H, Xing C, Zhang J, He B. Zhao H, et al. Reprod Health. 2021 Aug 18;18(1):171. doi: 10.1186/s12978-021-01207-7. Reprod Health. 2021. PMID: 34407851 Free PMC article.
BACKGROUND: Multiple oral insulin-sensitizing agents, such as metformin, thiazolidinediones, inositols, and berberine, have been proven safe and efficacious in improving the endocrine, metabolic, and reproductive abnormalities seen in polycystic ovary syndrome (PCOS), prov …
BACKGROUND: Multiple oral insulin-sensitizing agents, such as metformin, thiazolidinediones, inositols, and berberine, have been prov …
Effects of berberine on blood glucose in patients with type 2 diabetes mellitus: a systematic literature review and a meta-analysis.
Liang Y, Xu X, Yin M, Zhang Y, Huang L, Chen R, Ni J. Liang Y, et al. Endocr J. 2019 Jan 28;66(1):51-63. doi: 10.1507/endocrj.EJ18-0109. Epub 2018 Nov 3. Endocr J. 2019. PMID: 30393248 Free article.
The efficiency of Berberine combined with hypoglycaemics is better than either Berberine or hypoglycaemic alone. The dosage and treatment duration of Berberine and patients' age may modify the effect....
The efficiency of Berberine combined with hypoglycaemics is better than either Berberine or hypoglycaemic alone. The dosage an …
Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study.
Chen YX, Gao QY, Zou TH, Wang BM, Liu SD, Sheng JQ, Ren JL, Zou XP, Liu ZJ, Song YY, Xiao B, Sun XM, Dou XT, Cao HL, Yang XN, Li N, Kang Q, Zhu W, Xu HZ, Chen HM, Cao XC, Fang JY. Chen YX, et al. Lancet Gastroenterol Hepatol. 2020 Mar;5(3):267-275. doi: 10.1016/S2468-1253(19)30409-1. Epub 2020 Jan 8. Lancet Gastroenterol Hepatol. 2020. PMID: 31926918 Clinical Trial.
FINDINGS: Between Nov 14, 2014, and Dec 30, 2016, 553 participants were randomly assigned to the berberine group and 555 to the placebo group. The full analysis set consisted of 429 participants in the berberine group and 462 in the placebo group. 155 (36%) particip …
FINDINGS: Between Nov 14, 2014, and Dec 30, 2016, 553 participants were randomly assigned to the berberine group and 555 to the place …
Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins.
Kong W, Wei J, Abidi P, Lin M, Inaba S, Li C, Wang Y, Wang Z, Si S, Pan H, Wang S, Wu J, Wang Y, Li Z, Liu J, Jiang JD. Kong W, et al. Nat Med. 2004 Dec;10(12):1344-51. doi: 10.1038/nm1135. Epub 2004 Nov 7. Nat Med. 2004. PMID: 15531889 Free article. Clinical Trial.
We identify berberine (BBR), a compound isolated from a Chinese herb, as a new cholesterol-lowering drug. ...
We identify berberine (BBR), a compound isolated from a Chinese herb, as a new cholesterol-lowering drug. ...
The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review.
Nie Q, Li M, Huang C, Yuan Y, Liang Q, Ma X, Qiu T, Li J. Nie Q, et al. J Transl Med. 2024 Mar 1;22(1):225. doi: 10.1186/s12967-024-05011-2. J Transl Med. 2024. PMID: 38429794 Free PMC article.
Importantly, Berberine exhibited a favorable safety profile, with only mild gastrointestinal adverse events reported. CONCLUSION: This meta-analysis demonstrates berberine's efficacy in improving liver enzymes, lipid profile, and insulin sensitivity in NAFLD patient …
Importantly, Berberine exhibited a favorable safety profile, with only mild gastrointestinal adverse events reported. CONCLUSION: Thi …
219 results