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Berberine ameliorates chronic relapsing dextran sulfate sodium-induced colitis in C57BL/6 mice by suppressing Th17 responses.
Li YH, Xiao HT, Hu DD, Fatima S, Lin CY, Mu HX, Lee NP, Bian ZX. Li YH, et al. Pharmacol Res. 2016 Aug;110:227-239. doi: 10.1016/j.phrs.2016.02.010. Epub 2016 Mar 9. Pharmacol Res. 2016. PMID: 26969793
However, UC usually presents as a chronic condition with frequent relapse in patients. How berberine will act on chronic UC remains unclear. In the present study, we adopted dextran sulfate sodium (DSS)-induced chronic relapsing colitis model to …
However, UC usually presents as a chronic condition with frequent relapse in patients. How berberine will act on chronic UC re …
Protective role of berberine on ulcerative colitis through modulating enteric glial cells-intestinal epithelial cells-immune cells interactions.
Li H, Fan C, Lu H, Feng C, He P, Yang X, Xiang C, Zuo J, Tang W. Li H, et al. Acta Pharm Sin B. 2020 Mar;10(3):447-461. doi: 10.1016/j.apsb.2019.08.006. Epub 2019 Sep 5. Acta Pharm Sin B. 2020. PMID: 32140391 Free PMC article.
Administration of berberine can obviously ameliorate the disease severity and restore the mucosal barrier homeostasis of UC, closely accompanying by maintaining the residence of EGCs and attenuating inflammatory infiltrations and immune cells overactivation. ...Furt …
Administration of berberine can obviously ameliorate the disease severity and restore the mucosal barrier homeostasis of UC, c …
Berberrubine attenuates mucosal lesions and inflammation in dextran sodium sulfate-induced colitis in mice.
Yu XT, Xu YF, Huang YF, Qu C, Xu LQ, Su ZR, Zeng HF, Zheng L, Yi TG, Li HL, Chen JP, Zhang XJ. Yu XT, et al. PLoS One. 2018 Mar 14;13(3):e0194069. doi: 10.1371/journal.pone.0194069. eCollection 2018. PLoS One. 2018. PMID: 29538417 Free PMC article.
This study aimed to comparatively investigate the therapeutic effects of BB and BBR on dextran sodium sulfate (DSS)-induced mouse colitis model, and explore the potential underlying mechanism. ...BB treatment was shown to significantly ameliorate the DSS-indu …
This study aimed to comparatively investigate the therapeutic effects of BB and BBR on dextran sodium sulfate (DSS)-induced mo …
Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota.
Zhang XJ, Yuan ZW, Qu C, Yu XT, Huang T, Chen PV, Su ZR, Dou YX, Wu JZ, Zeng HF, Xie Y, Chen JN. Zhang XJ, et al. Pharmacol Res. 2018 Nov;137:34-46. doi: 10.1016/j.phrs.2018.09.010. Epub 2018 Sep 19. Pharmacol Res. 2018. PMID: 30243842
Inflammatory bowel disease (IBD), majorly include Crohn's disease (CD) and ulcerative colitis (UC), is chronic and relapsing inflammatory disorders of the gastrointestinal tract, which treatment options remain limited. Here we examined the therapeutic effects of an isoquin …
Inflammatory bowel disease (IBD), majorly include Crohn's disease (CD) and ulcerative colitis (UC), is chronic and relapsing inflamma …
Anti-inflammatory Efficacy of Combined Natural Alkaloid Berberine and S1PR Modulator Fingolimod at Low Doses in Ulcerative Colitis Preclinical Models.
Han Q, Tang HZ, Zou M, Zhao J, Wang L, Bian ZX, Li YH. Han Q, et al. J Nat Prod. 2020 Jun 26;83(6):1939-1949. doi: 10.1021/acs.jnatprod.0c00175. Epub 2020 May 20. J Nat Prod. 2020. PMID: 32432470
Whether fingolimod use can be extended to UC and how it interacts with berberine remain unclear. In the present study, the anti-inflammatory efficacies of berberine, fingolimod, and a combination of half-doses of them was examined in mice with dextran sulf
Whether fingolimod use can be extended to UC and how it interacts with berberine remain unclear. In the present study, the anti-infla …