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Efficacy of berberine in patients with type 2 diabetes mellitus.
Yin J, Xing H, Ye J. Yin J, et al. Metabolism. 2008 May;57(5):712-7. doi: 10.1016/j.metabol.2008.01.013. Metabolism. 2008. PMID: 18442638 Free PMC article. Clinical Trial.
This pilot study was to determine the efficacy and safety of berberine in the treatment of type 2 diabetes mellitus patients. In study A, 36 adults with newly diagnosed type 2 diabetes mellitus were randomly assigned …
This pilot study was to determine the efficacy and safety of berberine in the treatment of type 2 diabetes me …
Glucose-lowering effect of berberine on type 2 diabetes: A systematic review and meta-analysis.
Xie W, Su F, Wang G, Peng Z, Xu Y, Zhang Y, Xu N, Hou K, Hu Z, Chen Y, Chen R. Xie W, et al. Front Pharmacol. 2022 Nov 16;13:1015045. doi: 10.3389/fphar.2022.1015045. eCollection 2022. Front Pharmacol. 2022. PMID: 36467075 Free PMC article.
In order to shed light on the glucose-lowing effects of berberine in type 2 diabetes with different baseline fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c), we conducted a meta-analysis of randomized controlled trials. M …
In order to shed light on the glucose-lowing effects of berberine in type 2 diabetes with different baseline fas …
The Effect of Berberine on Metabolic Profiles in Type 2 Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Guo J, Chen H, Zhang X, Lou W, Zhang P, Qiu Y, Zhang C, Wang Y, Liu WJ. Guo J, et al. Oxid Med Cell Longev. 2021 Dec 15;2021:2074610. doi: 10.1155/2021/2074610. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 34956436 Free PMC article.
Glycemic metabolisms were the main factors studied, including glycosylated hemoglobin (HbA1c), fasting plasm glucose (FPG), and 2-hour postprandial blood glucose (2hPG). ...Serum creatinine (Scr), blood urea nitrogen (BUN), and adverse events were applied to evaluat …
Glycemic metabolisms were the main factors studied, including glycosylated hemoglobin (HbA1c), fasting plasm glucose (FPG), an …
Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study).
Zhang Y, Gu Y, Ren H, Wang S, Zhong H, Zhao X, Ma J, Gu X, Xue Y, Huang S, Yang J, Chen L, Chen G, Qu S, Liang J, Qin L, Huang Q, Peng Y, Li Q, Wang X, Kong P, Hou G, Gao M, Shi Z, Li X, Qiu Y, Zou Y, Yang H, Wang J, Xu G, Lai S, Li J, Ning G, Wang W. Zhang Y, et al. Nat Commun. 2020 Oct 6;11(1):5015. doi: 10.1038/s41467-020-18414-8. Nat Commun. 2020. PMID: 33024120 Free PMC article. Clinical Trial.
Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, merit metabolic homoeostasis. ...Four-hundred-nine eligible parti …
Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures altering gut microbiota like or …
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
Lan J, Zhao Y, Dong F, Yan Z, Zheng W, Fan J, Sun G. Lan J, et al. J Ethnopharmacol. 2015 Feb 23;161:69-81. doi: 10.1016/j.jep.2014.09.049. Epub 2014 Dec 10. J Ethnopharmacol. 2015. PMID: 25498346
ETHNOPHARMACOLOGICAL RELEVANCE: Berberine, extracted from Coptis Root and Phellodendron Chinese, has been frequently used for the adjuvant treatment of type 2 diabetes mellitus, hyperlipidemia, and hypertension in China. ...It is necessary to as …
ETHNOPHARMACOLOGICAL RELEVANCE: Berberine, extracted from Coptis Root and Phellodendron Chinese, has been frequently used for the adj …
Effects of administering berberine alone or in combination on type 2 diabetes mellitus: a systematic review and meta-analysis.
Wang J, Bi C, Xi H, Wei F. Wang J, et al. Front Pharmacol. 2024 Nov 21;15:1455534. doi: 10.3389/fphar.2024.1455534. eCollection 2024. Front Pharmacol. 2024. PMID: 39640489 Free PMC article. Review.
BACKGROUND: Despite the availability of multiple therapies for Type 2 diabetes mellitus (T2DM), challenges remain due to side effects and efficacy limitations. ...CONCLUSION: Current evidence suggests that BBR alone or in combination has significant po …
BACKGROUND: Despite the availability of multiple therapies for Type 2 diabetes mellitus (T2DM), challenges remai …
Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
Zhang Y, Li X, Zou D, Liu W, Yang J, Zhu N, Huo L, Wang M, Hong J, Wu P, Ren G, Ning G. Zhang Y, et al. J Clin Endocrinol Metab. 2008 Jul;93(7):2559-65. doi: 10.1210/jc.2007-2404. Epub 2008 Apr 8. J Clin Endocrinol Metab. 2008. PMID: 18397984 Clinical Trial.
OBJECTIVE: The objective of the study was to evaluate the efficacy and safety of berberine in the treatment of type 2 diabetic patients with dyslipidemia. DESIGN: One hundred sixteen patients with type 2 diabetes and dyslipidemia were randomly allocate …
OBJECTIVE: The objective of the study was to evaluate the efficacy and safety of berberine in the treatment of type 2 diabetic patien …
Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial.
Ji L, Ma J, Ma Y, Cheng Z, Gan S, Yuan G, Liu D, Li S, Liu Y, Xue X, Bai J, Wang K, Cai H, Li S, Liu K, Yu M, Liu L. Ji L, et al. JAMA Netw Open. 2025 Mar 3;8(3):e2462185. doi: 10.1001/jamanetworkopen.2024.62185. JAMA Netw Open. 2025. PMID: 40029660 Free PMC article. Clinical Trial.
IMPORTANCE: Few of the available therapies for type 2 diabetes (T2D) comprehensively address disease burden beyond glycemic control. ...DESIGN, SETTING, AND PARTICIPANTS: This phase 2 double-blind, placebo-controlled, 12-week randomized clinical trial, conduc …
IMPORTANCE: Few of the available therapies for type 2 diabetes (T2D) comprehensively address disease burden beyond glyc …
Effects of berberine on blood glucose in patients with type 2 diabetes mellitus: a systematic literature review and a meta-analysis.
Liang Y, Xu X, Yin M, Zhang Y, Huang L, Chen R, Ni J. Liang Y, et al. Endocr J. 2019 Jan 28;66(1):51-63. doi: 10.1507/endocrj.EJ18-0109. Epub 2018 Nov 3. Endocr J. 2019. PMID: 30393248 Free article.
We conducted a systematic review and meta-analysis to evaluate the effect of Berberine on glucose in patients with type 2 diabetes mellitus and identify potential factors may modifying the hypoglycemic effect. ...Twenty-eight studies were identi …
We conducted a systematic review and meta-analysis to evaluate the effect of Berberine on glucose in patients with type 2 …
The efficacy and safety of berberine in combination with cinnamon supplementation in patients with type 2 diabetes: a randomized clinical trial.
Mansour A, Sajjadi-Jazi SM, Gerami H, Khorasanian AS, Moalemzadeh B, Karimi S, Afrakoti NM, Mofid V, Mohajeri-Tehrani MR, Hekmatdoost A. Mansour A, et al. Eur J Nutr. 2025 Feb 25;64(2):102. doi: 10.1007/s00394-025-03618-9. Eur J Nutr. 2025. PMID: 39998703 Clinical Trial.
METHODS: Patients with type 2 diabetes were recruited to participate in a parallel, double-blind, placebo-controlled, randomized study. ...RESULTS: At the end of study, fasting blood sugar (FBS) (P = 0.031) and hemoglobin A1C (HbA1c) (P = 0.013) …
METHODS: Patients with type 2 diabetes were recruited to participate in a parallel, double-blind, placebo-controlled, r …
36 results