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Protective Effects of (E)-β-Caryophyllene (BCP) in Chronic Inflammation.
Scandiffio R, Geddo F, Cottone E, Querio G, Antoniotti S, Gallo MP, Maffei ME, Bovolin P. Scandiffio R, et al. Nutrients. 2020 Oct 26;12(11):3273. doi: 10.3390/nu12113273. Nutrients. 2020. PMID: 33114564 Free PMC article. Review.
(E)-beta-caryophyllene (BCP) is a bicyclic sesquiterpene widely distributed in the plant kingdom, where it contributes a unique aroma to essential oils and has a pivotal role in the survival and evolution of higher plants. ...Experimental results show the ability of …
(E)-beta-caryophyllene (BCP) is a bicyclic sesquiterpene widely distributed in the plant kingdom, where it contributes a uniqu …
β-Caryophyllene, a Dietary Cannabinoid, Protects Against Metabolic and Immune Dysregulation in a Diet-Induced Obesity Mouse Model.
Franco-Arroyo NN, Viveros-Paredes JM, Zepeda-Morales ASM, Roldán E, Márquez-Aguirre AL, Zepeda-Nuño JS, Velázquez-Juárez G, Fafutis-Morris M, López-Roa RI. Franco-Arroyo NN, et al. J Med Food. 2022 Oct;25(10):993-1002. doi: 10.1089/jmf.2021.0166. Epub 2022 Jul 6. J Med Food. 2022. PMID: 35792574
In the present study, we evaluated the effect of beta-caryophyllene on C57BL/6 mice using a diet-induced obesity model. Male mice were randomly assigned to the following groups over a 16-week period: (1) standard diet as lean control, (2) high-fat diet (HFD) as obes …
In the present study, we evaluated the effect of beta-caryophyllene on C57BL/6 mice using a diet-induced obesity model. Male m …
β-caryophyllene and β-caryophyllene oxide-natural compounds of anticancer and analgesic properties.
Fidyt K, Fiedorowicz A, Strządała L, Szumny A. Fidyt K, et al. Cancer Med. 2016 Oct;5(10):3007-3017. doi: 10.1002/cam4.816. Epub 2016 Sep 30. Cancer Med. 2016. PMID: 27696789 Free PMC article. Review.
Natural bicyclic sesquiterpenes, beta-caryophyllene (BCP) and beta-caryophyllene oxide (BCPO), are present in a large number of plants worldwide. ...The mechanisms underlying the anticancer activities of these sesquiterpenes are poorly described. BCP i …
Natural bicyclic sesquiterpenes, beta-caryophyllene (BCP) and beta-caryophyllene oxide (BCPO), are present in a …
Therapeutic Potential of β-Caryophyllene: A Dietary Cannabinoid in Diabetes and Associated Complications.
Hashiesh HM, Meeran MFN, Sharma C, Sadek B, Kaabi JA, Ojha SK. Hashiesh HM, et al. Nutrients. 2020 Sep 28;12(10):2963. doi: 10.3390/nu12102963. Nutrients. 2020. PMID: 32998300 Free PMC article. Review.
The phytochemicals classes, in particular sesquiterpenes received attention because of potent antioxidant, anti-inflammatory, and antihyperglycemic effects and health benefits mediating modulation of enzymes, receptors, and signaling pathways deranged in DM and its complications. …
The phytochemicals classes, in particular sesquiterpenes received attention because of potent antioxidant, anti-inflammatory, and antihyperg …
A mechanistic review on immunomodulatory effects of selective type two cannabinoid receptor β-caryophyllene.
Baradaran Rahimi V, Askari VR. Baradaran Rahimi V, et al. Biofactors. 2022 Jul;48(4):857-882. doi: 10.1002/biof.1869. Epub 2022 Jun 1. Biofactors. 2022. PMID: 35648433 Review.
beta-Caryophyllene (BCP) is a plant-derived compound and occurs naturally in various foods and spices, including cinnamon, citrus, fruits, clove, curry, and pepper. ...It has also been demonstrated that BCP suppresses both protein and mRNA expression levels of inter …
beta-Caryophyllene (BCP) is a plant-derived compound and occurs naturally in various foods and spices, including cinnamon, cit …
A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid.
Hashiesh HM, Sharma C, Goyal SN, Sadek B, Jha NK, Kaabi JA, Ojha S. Hashiesh HM, et al. Biomed Pharmacother. 2021 Aug;140:111639. doi: 10.1016/j.biopha.2021.111639. Epub 2021 Jun 3. Biomed Pharmacother. 2021. PMID: 34091179 Free article. Review.
The ligands activate CB2R are of endogenous, synthetic and plant origin. In recent years, beta-caryophyllene (BCP), a natural bicyclic sesquiterpene in cannabis as well as non-cannabis plants, has received attention due to its selective agonist property on CB2R. ...
The ligands activate CB2R are of endogenous, synthetic and plant origin. In recent years, beta-caryophyllene (BCP), a natural …
Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.
Russo EB. Russo EB. Br J Pharmacol. 2011 Aug;163(7):1344-64. doi: 10.1111/j.1476-5381.2011.01238.x. Br J Pharmacol. 2011. PMID: 21749363 Free PMC article. Review.
This review will explore another echelon of phytotherapeutic agents, the cannabis terpenoids: limonene, myrcene, alpha-pinene, linalool, beta-caryophyllene, caryophyllene oxide, nerolidol and phytol. Terpenoids share a precursor with phytocannabinoids, and ar …
This review will explore another echelon of phytotherapeutic agents, the cannabis terpenoids: limonene, myrcene, alpha-pinene, linalool, …
β-Caryophyllene nanoparticles design and development: Controlled drug delivery of cannabinoid CB2 agonist as a strategic tool towards neurodegeneration.
Alberti TB, Coelho DS, Maraschin M. Alberti TB, et al. Mater Sci Eng C Mater Biol Appl. 2021 Feb;121:111824. doi: 10.1016/j.msec.2020.111824. Epub 2020 Dec 29. Mater Sci Eng C Mater Biol Appl. 2021. PMID: 33579467
The sesquiterpene beta-caryophyllene (BCP) is a structurally singular cannabinoid and a selective agonist of the CB2 receptor, which in addition to being expressed in the CNS, is intrinsically expressed within the immune system and lacks psychoactivity. ...BC …
The sesquiterpene beta-caryophyllene (BCP) is a structurally singular cannabinoid and a selective agonist of the CB2 re …
β-Caryophyllene, a natural bicyclic sesquiterpene attenuates β-adrenergic agonist-induced myocardial injury in a cannabinoid receptor-2 dependent and independent manner.
Meeran MFN, Laham F, Azimullah S, Sharma C, Al Kaabi AJ, Tariq S, Adeghate E, Goyal SN, Ojha S. Meeran MFN, et al. Free Radic Biol Med. 2021 May 1;167:348-366. doi: 10.1016/j.freeradbiomed.2021.01.046. Epub 2021 Feb 13. Free Radic Biol Med. 2021. PMID: 33588052
In the present study, we investigated the cardioprotective effect of beta-caryophyllene (BCP), a naturally occurring dietary cannabinoid in rat model of MI. ...AM630 (1 mg/kg), a CB2 receptor antagonist, was injected intraperitoneal as a pharmacological chall …
In the present study, we investigated the cardioprotective effect of beta-caryophyllene (BCP), a naturally occurring dietary …
β-Caryophyllene, A Natural Dietary CB2 Receptor Selective Cannabinoid can be a Candidate to Target the Trinity of Infection, Immunity, and Inflammation in COVID-19.
Jha NK, Sharma C, Hashiesh HM, Arunachalam S, Meeran MN, Javed H, Patil CR, Goyal SN, Ojha S. Jha NK, et al. Front Pharmacol. 2021 May 14;12:590201. doi: 10.3389/fphar.2021.590201. eCollection 2021. Front Pharmacol. 2021. PMID: 34054510 Free PMC article.
One of the most promising therapeutic targets for the modulation of immune-inflammatory responses is the endocannabinoid system, particularly the activation of cannabinoid type 2 receptors (CB2R), a G-protein coupled receptor which mediates the anti-inflammatory properties …
One of the most promising therapeutic targets for the modulation of immune-inflammatory responses is the endocannabinoid system, particularl …
147 results