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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1981 1
1982 1
1983 1
1984 1
1985 4
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1989 3
1990 8
1991 11
1992 16
1993 28
1994 34
1995 34
1996 28
1997 50
1998 56
1999 57
2000 48
2001 52
2002 42
2003 62
2004 68
2005 42
2006 50
2007 55
2008 48
2009 49
2010 53
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2012 61
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2014 38
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2024 14

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1,239 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Role of Beta-Carotene in Lung Cancer Primary Chemoprevention: A Systematic Review with Meta-Analysis and Meta-Regression.
Kordiak J, Bielec F, Jabłoński S, Pastuszak-Lewandoska D. Kordiak J, et al. Nutrients. 2022 Mar 24;14(7):1361. doi: 10.3390/nu14071361. Nutrients. 2022. PMID: 35405977 Free PMC article. Review.
A meta-regression found no relationship between the beta-carotene supplementation dose and the size of the negative effect associated with lung cancer risk. Our findings indicate that beta-carotene supplementation has no effect on lung cancer risk. Mor …
A meta-regression found no relationship between the beta-carotene supplementation dose and the size of the negative effect ass …
Sunscreen and prevention of skin aging: a randomized trial.
Hughes MC, Williams GM, Baker P, Green AC. Hughes MC, et al. Ann Intern Med. 2013 Jun 4;158(11):781-90. doi: 10.7326/0003-4819-158-11-201306040-00002. Ann Intern Med. 2013. PMID: 23732711 Clinical Trial.
OBJECTIVE: To determine whether regular use of sunscreen compared with discretionary use or beta-carotene supplements compared with placebo retard skin aging, measured by degree of photoaging. ...INTERVENTION: Random assignment into 4 groups: daily use of broad-spec …
OBJECTIVE: To determine whether regular use of sunscreen compared with discretionary use or beta-carotene supplements compared …
Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial.
Age-Related Eye Disease Study 2 Research Group. Age-Related Eye Disease Study 2 Research Group. JAMA. 2013 May 15;309(19):2005-15. doi: 10.1001/jama.2013.4997. JAMA. 2013. PMID: 23644932 Clinical Trial.
IMPORTANCE: Oral supplementation with the Age-Related Eye Disease Study (AREDS) formulation (antioxidant vitamins C and E, beta carotene, and zinc) has been shown to reduce the risk of progression to advanced age-related macular degeneration (AMD). ...Comparison wit …
IMPORTANCE: Oral supplementation with the Age-Related Eye Disease Study (AREDS) formulation (antioxidant vitamins C and E, beta ca
Investigating Causal Associations of Circulating Micronutrients Concentrations with the Risk of Lung Cancer: A Mendelian Randomization Study.
Yan H, Jin X, Yin L, Zhu C, Feng G. Yan H, et al. Nutrients. 2022 Oct 31;14(21):4569. doi: 10.3390/nu14214569. Nutrients. 2022. PMID: 36364831 Free PMC article.
The instrumental variables (IVs) of 11 micronutrients (beta-carotene, calcium, copper, folate, lycopene, magnesium, phosphorus, retinol, selenium, zinc, and vitamin B6) were screened from the published genome-wide association studies (GWAS). ...Our study suggested t …
The instrumental variables (IVs) of 11 micronutrients (beta-carotene, calcium, copper, folate, lycopene, magnesium, phosphorus …
Development of a comprehensive dietary antioxidant index and application to lung cancer risk in a cohort of male smokers.
Wright ME, Mayne ST, Stolzenberg-Solomon RZ, Li Z, Pietinen P, Taylor PR, Virtamo J, Albanes D. Wright ME, et al. Am J Epidemiol. 2004 Jul 1;160(1):68-76. doi: 10.1093/aje/kwh173. Am J Epidemiol. 2004. PMID: 15229119 Clinical Trial.
The authors constructed a dietary antioxidant index and evaluated its ability to predict lung cancer risk within the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study cohort. At baseline (1985-1988), 27,111 Finnish male smokers aged 50-69 years completed a die …
The authors constructed a dietary antioxidant index and evaluated its ability to predict lung cancer risk within the Alpha-Tocopherol, Be
Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomised controlled trial.
Green A, Williams G, Neale R, Hart V, Leslie D, Parsons P, Marks GC, Gaffney P, Battistutta D, Frost C, Lang C, Russell A. Green A, et al. Lancet. 1999 Aug 28;354(9180):723-9. doi: 10.1016/S0140-6736(98)12168-2. Lancet. 1999. PMID: 10475183 Clinical Trial.
METHODS: In a community-based randomised trial with a 2 by 2 factorial design, individuals were assigned to four treatment groups: daily application of a sun protection factor 15-plus sunscreen to the head, neck, arms, and hands, and betacarotene supplementation (30 mg per …
METHODS: In a community-based randomised trial with a 2 by 2 factorial design, individuals were assigned to four treatment groups: daily app …
Dietary vitamin and carotenoid intake and risk of age-related cataract.
Jiang H, Yin Y, Wu CR, Liu Y, Guo F, Li M, Ma L. Jiang H, et al. Am J Clin Nutr. 2019 Jan 1;109(1):43-54. doi: 10.1093/ajcn/nqy270. Am J Clin Nutr. 2019. PMID: 30624584 Free article. Review.

Most vitamins and carotenoids were significantly associated with reduced risk of ARC in the cohort studies, including vitamin A (RR: 0.81; 95% CI: 0.71, 0.92; P = 0.001), vitamin C (RR: 0.80; 95% CI: 0.72, 0.88; P < 0.001), vitamin E (RR: 0.90; 95% CI: 0.80, 1.00; P = 0.049),

Most vitamins and carotenoids were significantly associated with reduced risk of ARC in the cohort studies, including vitamin A (RR: 0.81; 9 …
Vitamins C, E, and beta-Carotene and Risk of Type 2 Diabetes: A Systematic Review and Meta-Analysis.
Lampousi AM, Lundberg T, Löfvenborg JE, Carlsson S. Lampousi AM, et al. Adv Nutr. 2024 May;15(5):100211. doi: 10.1016/j.advnut.2024.100211. Epub 2024 Mar 15. Adv Nutr. 2024. PMID: 38493875 Free PMC article. Review.
The lowest risk was seen at intakes of 70 mg/d of vitamin C (RR: 0.76; CI: 0.61, 0.95), 12 mg/d of vitamin E (RR: 0.72; CI: 0.61, 0.86), and 4 mg/d of beta-carotene (RR: 0.78; CI: 0.65, 0.94). Supplementation with vitamin E (RR: 1.01; CI: 0.93, 1.10) or beta- …
The lowest risk was seen at intakes of 70 mg/d of vitamin C (RR: 0.76; CI: 0.61, 0.95), 12 mg/d of vitamin E (RR: 0.72; CI: 0.61, 0.86), and …
Re-remembering the influence of randomized beta-carotene on cognitive decline.
Kopec RE, Chasman DI, Okereke OI, Sesso HD. Kopec RE, et al. Alzheimers Dement. 2023 Aug;19(8):3718-3721. doi: 10.1002/alz.13018. Epub 2023 Mar 20. Alzheimers Dement. 2023. PMID: 36939000 Clinical Trial.
As a motivating example, we highlight an ancillary report from the Physicians' Health Study, where subjects randomized to beta-carotene (a provitamin A carotenoid) had a more attenuated change in longitudinal global cognitive performance and verbal memory, as compar …
As a motivating example, we highlight an ancillary report from the Physicians' Health Study, where subjects randomized to beta-car
Antioxidant supplements for liver diseases.
Bjelakovic G, Gluud LL, Nikolova D, Bjelakovic M, Nagorni A, Gluud C. Bjelakovic G, et al. Cochrane Database Syst Rev. 2011 Mar 16;(3):CD007749. doi: 10.1002/14651858.CD007749.pub2. Cochrane Database Syst Rev. 2011. PMID: 21412909 Review.
SELECTION CRITERIA: We considered for inclusion randomised trials that compared antioxidant supplements (beta-carotene, vitamin A, C, E, and selenium) versus placebo or no intervention for autoimmune liver diseases, viral hepatitis, alcoholic liver disease, and cirr …
SELECTION CRITERIA: We considered for inclusion randomised trials that compared antioxidant supplements (beta-carotene, vitami …
1,239 results