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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1975 1
1976 3
1979 1
1982 2
1983 2
1984 2
1985 3
1986 8
1987 8
1988 11
1989 5
1990 14
1991 11
1992 9
1993 13
1994 8
1995 13
1996 13
1997 18
1998 13
1999 20
2000 41
2001 21
2002 36
2003 38
2004 39
2005 71
2006 68
2007 65
2008 61
2009 63
2010 73
2011 79
2012 81
2013 59
2014 60
2015 49
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2017 40
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2021 46
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2023 33
2024 49
2025 80
2026 33

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1,338 results

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Page 1
Testosterone Assays.
King B, Natale C, Hellstrom WJG. King B, et al. Urol Clin North Am. 2022 Nov;49(4):665-677. doi: 10.1016/j.ucl.2022.07.009. Epub 2022 Oct 7. Urol Clin North Am. 2022. PMID: 36309422 Review.
Total testosterone remains the most accessible for standard laboratories, while free testosterone and bioavailable testosterone may be useful adjuncts, particularly in men with low borderline testosterone values. Mass spectrometry is the gold st …
Total testosterone remains the most accessible for standard laboratories, while free testosterone and bioavailable t …
[Contribution of bioavailable testosterone assay for the diagnosis of androgen deficiency in elderly men].
Lejeune H, Déchaud H, Pugeat M. Lejeune H, et al. Ann Endocrinol (Paris). 2003 Apr;64(2):117-25. Ann Endocrinol (Paris). 2003. PMID: 12773947 Review. French.
While total testosterone levels decrease, sex hormone binding globulin (SHBG) levels on the contrary increase with age, with the result that the levels of free and non-SHBG-bound testosterone (corresponding to the fraction which is bioavailable to target cell …
While total testosterone levels decrease, sex hormone binding globulin (SHBG) levels on the contrary increase with age, with the resu …
Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline.
Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS, Montori VM; Task Force, Endocrine Society. Bhasin S, et al. J Clin Endocrinol Metab. 2010 Jun;95(6):2536-59. doi: 10.1210/jc.2009-2354. J Clin Endocrinol Metab. 2010. PMID: 20525905 Free article. Review.
CONCLUSIONS: We recommend making a diagnosis of androgen deficiency only in men with consistent symptoms and signs and unequivocally low serum testosterone levels. We suggest the measurement of morning total testosterone level by a reliable assay as the initi …
CONCLUSIONS: We recommend making a diagnosis of androgen deficiency only in men with consistent symptoms and signs and unequivocally low ser …
Uncovering novel protein pathways regulating bioavailable testosterone through sex hormone-binding globulin.
Hong Y. Hong Y. Comput Biol Chem. 2026 Feb;120(Pt 2):108742. doi: 10.1016/j.compbiolchem.2025.108742. Epub 2025 Oct 24. Comput Biol Chem. 2026. PMID: 41161126
Bioavailable testosterone (BAT), a critical factor for reproductive, metabolic, and psychological health, is primarily regulated by sex hormone-binding globulin (SHBG). ...Our findings reveal novel protein regulators of testosterone bioavailability thr …
Bioavailable testosterone (BAT), a critical factor for reproductive, metabolic, and psychological health, is primarily regulat …
Bioavailable testosterone reduces the risk of lung squamous cell carcinoma: a comprehensive data study.
Luo J, Liu P, Song J, Li Y, Xu M. Luo J, et al. J Transl Med. 2025 Dec 29;24(1):118. doi: 10.1186/s12967-025-07639-0. J Transl Med. 2025. PMID: 41462265 Free PMC article.
BACKGROUND: The association between testosterone and lung cancer remains unclear. This study investigates the relationship between testosterone levels and lung cancer risk, focusing on bioavailable testosterone levels (BTLs), total testosterone …
BACKGROUND: The association between testosterone and lung cancer remains unclear. This study investigates the relationship between …
A critical evaluation of simple methods for the estimation of free testosterone in serum.
Vermeulen A, Verdonck L, Kaufman JM. Vermeulen A, et al. J Clin Endocrinol Metab. 1999 Oct;84(10):3666-72. doi: 10.1210/jcem.84.10.6079. J Clin Endocrinol Metab. 1999. PMID: 10523012
Hence, it is important to have reliable indexes of these fractions. The apparent free testosterone (T) concentration obtained by equilibrium dialysis (AFTC) as well as the fraction of serum T not precipitated by 50% ammonium sulfate concentration (non-SHBG-T; SHBG, sex hor …
Hence, it is important to have reliable indexes of these fractions. The apparent free testosterone (T) concentration obtained by equi …
Monitoring testosterone levels in testosterone-treated men.
Winters SJ. Winters SJ. Curr Med Res Opin. 2016;32(2):271-2. doi: 10.1185/03007995.2015.1118023. Epub 2015 Nov 25. Curr Med Res Opin. 2016. PMID: 26551968
Dose adjustment with transdermal testosterone preparations should recognize the variability of serum total testosterone levels between applications and over the course of 24 h. Dose adjustments are also made difficult by between-laboratory assay variability. …
Dose adjustment with transdermal testosterone preparations should recognize the variability of serum total testosterone levels …
Assessment of free testosterone concentration.
Keevil BG, Adaway J. Keevil BG, et al. J Steroid Biochem Mol Biol. 2019 Jun;190:207-211. doi: 10.1016/j.jsbmb.2019.04.008. Epub 2019 Apr 7. J Steroid Biochem Mol Biol. 2019. PMID: 30970279 Review.
If the free hormone hypothesis is to be believed, then calculated free testosterone may offer the best way forward but better equations are needed to improve accuracy and these should be derived from detailed knowledge of testosterone binding to SHBG. There is still …
If the free hormone hypothesis is to be believed, then calculated free testosterone may offer the best way forward but better equatio …
Mendelian randomization analyses identified bioavailable testosterone mediates the effect of sex hormone-binding globulin on prostate cancer.
Wan B, Lu L, Lv C. Wan B, et al. Andrology. 2023 Sep;11(6):1023-1030. doi: 10.1111/andr.13358. Epub 2023 Jan 12. Andrology. 2023. PMID: 36524281 Free article.
The total effect of sex hormone-binding globulin on prostate cancer risk was decomposed into direct and indirect effects through the mediator, bioavailable testosterone. An inverse-variance-weighted method was the primary Mendelian randomization analysis meth …
The total effect of sex hormone-binding globulin on prostate cancer risk was decomposed into direct and indirect effects through the mediato …
Urinary equol is associated with bioavailable testosterone but not total testosterone in women.
Dong H, Xiong F, Zhong Q, Li Y, Liu M, Ling W, Tang X, Chen Y. Dong H, et al. Endocr J. 2020 Mar 28;67(3):257-266. doi: 10.1507/endocrj.EJ19-0319. Epub 2019 Nov 19. Endocr J. 2020. PMID: 31748434 Free article.
Little is known about the association between equol and bioavailable testosterone (BT) in adults. In this study, we examined the associations of urinary equol concentrations with serum concentrations of total, bioavailable and free testosterone (FT), d …
Little is known about the association between equol and bioavailable testosterone (BT) in adults. In this study, we examined t …
1,338 results