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Complications of collagen biostimulators in Brazil: Description of products, treatments, and evolution of 55 cases.
Ianhez M, de Goés E Silva Freire G, Sigrist RMS, Colpas PT, de Faria IA, Parada MOAB, Miot HA. Ianhez M, et al. J Cosmet Dermatol. 2024 Sep;23(9):2829-2835. doi: 10.1111/jocd.16343. Epub 2024 May 1. J Cosmet Dermatol. 2024. PMID: 38693639
However, there is a lack of comparative data regarding poly-L-lactic acid (PLLA), calcium hydroxyapatite (CaHA), and polycaprolactone (PCL) known as collagen biostimulators. AIMS: This study addressed the complications of collagen biostimulators concer …
However, there is a lack of comparative data regarding poly-L-lactic acid (PLLA), calcium hydroxyapatite (CaHA), and polycaprolactone (PCL) …
Efficacy and Safety of Poly-l-Lactic Acid in Facial Aesthetics: A Systematic Review.
Signori R, Barbosa AP, Cezar-Dos-Santos F, Carbone AC, Ventura S, Nobre BBS, Neves MLBB, Câmara-Souza MB, Poluha RL, De la Torre Canales G. Signori R, et al. Polymers (Basel). 2024 Sep 11;16(18):2564. doi: 10.3390/polym16182564. Polymers (Basel). 2024. PMID: 39339028 Free PMC article. Review.
Eleven RCTs out of 1467 identified citations were included. Four studies showed increased dermal thickness, significant improvement in facial lipoatrophy severity and aesthetic clinical scores, after PLLA treatment with its effects sustained for at least 25 months. Two stu …
Eleven RCTs out of 1467 identified citations were included. Four studies showed increased dermal thickness, significant improvement i …
Consensus Recommendations for the Use of Hyperdiluted Calcium Hydroxyapatite (Radiesse) as a Face and Body Biostimulatory Agent.
de Almeida AT, Figueredo V, da Cunha ALG, Casabona G, Costa de Faria JR, Alves EV, Sato M, Branco A, Guarnieri C, Palermo E. de Almeida AT, et al. Plast Reconstr Surg Glob Open. 2019 Mar 14;7(3):e2160. doi: 10.1097/GOX.0000000000002160. eCollection 2019 Mar. Plast Reconstr Surg Glob Open. 2019. PMID: 31044123 Free PMC article.
BACKGROUND: Calcium hydroxyapatite (CaHA) is a well-established collagen stimulator. In recent years, it has been increasingly used in hyperdiluted form as a biostimulatory agent rather than a volumizing filler to improve skin quality and firmness in both facial and corpor …
BACKGROUND: Calcium hydroxyapatite (CaHA) is a well-established collagen stimulator. In recent years, it has been increasingly used i …
A Systematic Review on the Effectiveness and Safety of Combining Biostimulators with Botulinum Toxin, Dermal Fillers, and Energy-Based Devices.
Tam E, Choo JPS, Rao P, Webb WR, Carruthers JDA, Rahman E. Tam E, et al. Aesthetic Plast Surg. 2025 May;49(10):2809-2833. doi: 10.1007/s00266-024-04627-5. Epub 2024 Dec 24. Aesthetic Plast Surg. 2025. PMID: 39719485
The search included terms related to biostimulators and combination treatments. Studies meeting inclusion criteria reported clinical outcomes of combined biostimulator treatments, including effectiveness, safety, patient satisfaction, and adverse effects. ...These s …
The search included terms related to biostimulators and combination treatments. Studies meeting inclusion criteria reported clinical …
Recommendations for volume augmentation and rejuvenation of the face and hands with the new generation polycaprolactone-based collagen stimulator (Ellanse()).
de Melo F, Nicolau P, Piovano L, Lin SL, Baptista-Fernandes T, King MI, Camporese A, Hong K, Khattar MM, Christen MO. de Melo F, et al. Clin Cosmet Investig Dermatol. 2017 Nov 8;10:431-440. doi: 10.2147/CCID.S145195. eCollection 2017. Clin Cosmet Investig Dermatol. 2017. PMID: 29184426 Free PMC article. Review.
The latest advances in filler technology include collagen biostimulators that exert their esthetic effect by promoting neocollagenesis. One such product is the next-generation collagen biostimulator (Ellanse()) that demonstrates properties as yet unsee …
The latest advances in filler technology include collagen biostimulators that exert their esthetic effect by promoting neocoll …
Combining topical dermal infused exosomes with injected calcium hydroxylapatite for enhanced tissue biostimulation.
Chernoff G. Chernoff G. J Cosmet Dermatol. 2023 Mar;22 Suppl 1:15-27. doi: 10.1111/jocd.15695. J Cosmet Dermatol. 2023. PMID: 36988469
Twenty patients underwent facial biostimulatory dermal infusion alone, to determine if this method allowed adequate exosome absorption. ...Five patients underwent Facial Dilute CaHA injection (1:1 dilution) alone, without dermal infusion. Five patients underwent nec …
Twenty patients underwent facial biostimulatory dermal infusion alone, to determine if this method allowed adequate exosome absorptio …
Effect of poly-L-lactic acid and polydioxanone biostimulators on type I and III collagen biosynthesis.
Bernardo RTR, Oliveira RCG, Freitas KMS, Albergaria-Barbosa JR, Rizzatti-Barbosa CM. Bernardo RTR, et al. Skin Res Technol. 2024 Apr;30(4):e13681. doi: 10.1111/srt.13681. Skin Res Technol. 2024. PMID: 38584576 Free PMC article.
OBJECTIVE: Safe, effective, and biocompatible minimally invasive procedures with the potential to stimulate collagen production have been made to recover dermal thickness and skin quality. The main of this animal model experiment was to observe the effect of poly-L- …
OBJECTIVE: Safe, effective, and biocompatible minimally invasive procedures with the potential to stimulate collagen production have …
Safety of the Immediate Reconstitution of Poly-l-Lactic Acid for Facial and Body Treatment-A Multicenter Retrospective Study.
Vasconcelos-Berg R, Real J, Wenz F, Avelar LET. Vasconcelos-Berg R, et al. J Cosmet Dermatol. 2024 Dec;23(12):3918-3923. doi: 10.1111/jocd.16560. Epub 2024 Sep 17. J Cosmet Dermatol. 2024. PMID: 39285829 Free PMC article.
BACKGROUND: Poly-l-lactic acid (PLLA-SCA; Sculptra) was approved in 1999 in Europe and 2004 in United States as a collagen biostimulator. It is a freeze-dried preparation containing 150 mg PLLA-SCA per vial and, since approval, has been recommended to be reconstitut …
BACKGROUND: Poly-l-lactic acid (PLLA-SCA; Sculptra) was approved in 1999 in Europe and 2004 in United States as a collagen biostim …
Exploring the Safety and Satisfaction of Patients Injected With Collagen Biostimulators-A Prospective Investigation Into Injectable Poly-l-Lactic Acid (PLLA).
Bravo BSF, Calvacante T, Nobre CS, Bravo LG, Zafra MC, Elias MC. Bravo BSF, et al. J Cosmet Dermatol. 2025 Feb;24(2):e16723. doi: 10.1111/jocd.16723. Epub 2024 Dec 12. J Cosmet Dermatol. 2025. PMID: 39663956 Free PMC article.
The patients' mid and lower face was treated by injecting Rennova Elleva (a collagen biostimulator containing 210 mg of PLLA) into the zygomatic and pre-masseteric regions. ...CONCLUSION: Rennova Elleva, a PLLA-based collagen biostimulator, is safe and …
The patients' mid and lower face was treated by injecting Rennova Elleva (a collagen biostimulator containing 210 mg of PLLA) …
41 results