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71 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Drug Efficacy in the Treatment of Antipsychotic-Induced Akathisia: A Systematic Review and Network Meta-Analysis.
Gerolymos C, Barazer R, Yon DK, Loundou A, Boyer L, Fond G. Gerolymos C, et al. JAMA Netw Open. 2024 Mar 4;7(3):e241527. doi: 10.1001/jamanetworkopen.2024.1527. JAMA Netw Open. 2024. PMID: 38451521 Free PMC article.
Mirtazapine (15 mg/d for 5 days; SMD, -1.20; 95% CI, -1.83 to -0.58), biperiden (6 mg/d for 14 days; SMD, -1.01; 95% CI, -1.69 to -0.34), vitamin B6 (600-1200 mg/d for 5 days; SMD, -0.92; 95% CI, -1.57 to -0.26), trazodone (50 mg/d for 5 days; SMD, -0.84; 95% CI, -1.54 to …
Mirtazapine (15 mg/d for 5 days; SMD, -1.20; 95% CI, -1.83 to -0.58), biperiden (6 mg/d for 14 days; SMD, -1.01; 95% CI, -1.69 to -0. …
Biperiden Challenge Model in Healthy Elderly as Proof-of-Pharmacology Tool: A Randomized, Placebo-Controlled Trial.
Bakker C, van Esdonk MJ, Stuurman RFE, Borghans LGJM, de Kam ML, van Gerven JMA, Groeneveld GJ. Bakker C, et al. J Clin Pharmacol. 2021 Nov;61(11):1466-1478. doi: 10.1002/jcph.1913. Epub 2021 Jul 29. J Clin Pharmacol. 2021. PMID: 34021607 Free PMC article. Clinical Trial.
A challenge with the M(1) mAChR antagonist biperiden could be used to demonstrate procognitive and pharmacological effects of selective M(1) mAChR agonists. ...Therefore a biperiden pharmacological challenge model can be used for proof-of-pharmacology studies and to …
A challenge with the M(1) mAChR antagonist biperiden could be used to demonstrate procognitive and pharmacological effects of selecti …
The antimuscarinic agent biperiden selectively impairs recognition of abstract figures without affecting the processing of non-words.
Toth M, Sambeth A, Blokland A. Toth M, et al. Hum Psychopharmacol. 2022 Mar;37(2):e2819. doi: 10.1002/hup.2819. Epub 2021 Sep 17. Hum Psychopharmacol. 2022. PMID: 34533841 Free PMC article. Clinical Trial.
The aim was to examine whether 4 mg biperiden could model the recognition memory impairment seen in healthy aging. METHODS: A double-blind, placebo-controlled, two-way crossover study was conducted. ...The recognition of the new abstract figures was unaffected by the drug. …
The aim was to examine whether 4 mg biperiden could model the recognition memory impairment seen in healthy aging. METHODS: A double- …
Biperiden selectively induces memory impairment in healthy volunteers: no interaction with citalopram.
Sambeth A, Riedel WJ, Klinkenberg I, Kähkönen S, Blokland A. Sambeth A, et al. Psychopharmacology (Berl). 2015 Jun;232(11):1887-97. doi: 10.1007/s00213-014-3822-9. Epub 2014 Dec 4. Psychopharmacology (Berl). 2015. PMID: 25466702 Clinical Trial.
Cognitive tests (verbal memory, continuous recognition memory, spatial memory, choice reaction) were performed 4 and 1 h after treatment with citalopram and biperiden, respectively. RESULTS: Biperiden impaired memory performance in the verbal learning task, the cont …
Cognitive tests (verbal memory, continuous recognition memory, spatial memory, choice reaction) were performed 4 and 1 h after treatment wit …
Biperiden effects and plasma levels in volunteers.
Hollmann M, Brode E, Greger G, Müller-Peltzer H, Wetzelsberger N. Hollmann M, et al. Eur J Clin Pharmacol. 1984;27(5):619-21. doi: 10.1007/BF00556903. Eur J Clin Pharmacol. 1984. PMID: 6519170 Clinical Trial.
The pharmacokinetics of biperiden was studied and compared with pharmacodynamics (pupil size, accommodation, self-rating mood scale) in 6 healthy volunteers. A single-blind cross-over design was employed with placebo and biperiden (4 mg as commercially available tab …
The pharmacokinetics of biperiden was studied and compared with pharmacodynamics (pupil size, accommodation, self-rating mood scale) …
miR-9-5p is Downregulated in Serum Extracellular Vesicles of Patients Treated with Biperiden After Traumatic Brain Injury.
Villena-Rueda BE, Kajitani GS, Ota VK, Honorato-Mauer J, Santoro ML, Bugiga AVG, Rosa JS, Asprino PF, Meneghetti P, Torrecilhas AC, Intasqui P, Bertolla RP, Foresti ML, da Graça Naffah-Mazzacoratti M, de Moraes Mello LEA, Belangero SI. Villena-Rueda BE, et al. Mol Neurobiol. 2024 Nov;61(11):9595-9607. doi: 10.1007/s12035-024-04194-5. Epub 2024 Apr 26. Mol Neurobiol. 2024. PMID: 38664300 Clinical Trial.
A total of 18 patients received biperiden, with three subjects developing PTE, and 19 received placebo, with two developing PTE. ...These findings indicate that biperiden may alter miR-9-5p expression in serum EVs, which may play a role in TBI resolution....
A total of 18 patients received biperiden, with three subjects developing PTE, and 19 received placebo, with two developing PTE. ...T …
Interaction study between remoxipride and biperiden.
Yisak W, Farde L, von Bahr C, Nilsson LB, Fredriksson G, Ogenstad S. Yisak W, et al. Psychopharmacology (Berl). 1993;111(1):27-32. doi: 10.1007/BF02257403. Psychopharmacology (Berl). 1993. PMID: 7870930 Clinical Trial.
Twelve healthy male volunteers took part in a double-blind randomised cross-over study composed of three treatment sessions: remoxipride 100 mg; remoxipride 100 mg plus biperiden 4 mg; and biperiden 4 mg. Plasma and urine concentrations of remoxipride and biperid …
Twelve healthy male volunteers took part in a double-blind randomised cross-over study composed of three treatment sessions: remoxipride 100 …
Effects of biperiden on the treatment of cocaine/crack addiction: a randomised, double-blind, placebo-controlled trial.
Dieckmann LH, Ramos AC, Silva EA, Justo LP, Sabioni P, Frade IF, de Souza AL, Galduróz JC. Dieckmann LH, et al. Eur Neuropsychopharmacol. 2014 Aug;24(8):1196-202. doi: 10.1016/j.euroneuro.2014.06.001. Epub 2014 Jun 12. Eur Neuropsychopharmacol. 2014. PMID: 24974353 Clinical Trial.
Two groups were compared: placebo (n=55) or biperiden (n=56) combined with weekly sessions of brief group cognitive-behavioural therapy. ...There was statistically significant difference between the craving score in the biperiden group. Pharmacological blockade of t …
Two groups were compared: placebo (n=55) or biperiden (n=56) combined with weekly sessions of brief group cognitive-behavioural thera …
Preliminary investigation of the administration of biperiden to reduce relapses in individuals with cocaine/crack user disorder: A randomized controlled clinical trial.
Junior MSC, Bezerra AG, Curado DF, Gregório RP, Galduróz JCF. Junior MSC, et al. Pharmacol Biochem Behav. 2024 Apr;237:173725. doi: 10.1016/j.pbb.2024.173725. Epub 2024 Feb 9. Pharmacol Biochem Behav. 2024. PMID: 38340989 Clinical Trial.

RESULTS: The sample comprised 128 people, with 61 in the control group and 67 in the biperiden group. Lower substance consumption was observed in the group that received biperiden treatment two (bT2 = -2.2 [-3.3; -1.0], p < 0.001) and six months (bT4 = -6, 2 [-8.

…
RESULTS: The sample comprised 128 people, with 61 in the control group and 67 in the biperiden group. Lower substance consumption was …
Effects of biperiden and acute tryptophan depletion and their combination on verbal word memory and EEG.
Borghans LG, Blokland A, Sambeth A. Borghans LG, et al. Psychopharmacology (Berl). 2017 Apr;234(7):1135-1143. doi: 10.1007/s00213-017-4549-1. Epub 2017 Feb 16. Psychopharmacology (Berl). 2017. PMID: 28210777 Free PMC article. Clinical Trial.
In this study, we tested the effects of the muscarinic M1 antagonist biperiden, acute tryptophan depletion (ATD), and the interaction between the two on episodic memory using the verbal learning task. ...RESULTS: Results revealed decreased scores on the delayed recall afte …
In this study, we tested the effects of the muscarinic M1 antagonist biperiden, acute tryptophan depletion (ATD), and the interaction …
71 results

Searches related to "biperiden"