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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
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2012 6
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249 results

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Page 1
The clinician's guide to prevention and treatment of osteoporosis.
LeBoff MS, Greenspan SL, Insogna KL, Lewiecki EM, Saag KG, Singer AJ, Siris ES. LeBoff MS, et al. Osteoporos Int. 2022 Oct;33(10):2049-2102. doi: 10.1007/s00198-021-05900-y. Epub 2022 Apr 28. Osteoporos Int. 2022. PMID: 35478046 Free PMC article.
Osteoporosis detection, diagnosis, and treatment should be routine practice in all adult healthcare settings. The Bone Health and Osteoporosis Foundation (BHOF) - formerly the National Osteoporosis Foundation - first published the Clinician's Guide in 1999 to provide accur …
Osteoporosis detection, diagnosis, and treatment should be routine practice in all adult healthcare settings. The Bone Health and Ost …
Bisphosphonate drug holiday: choosing appropriate candidates.
Ro C, Cooper O. Ro C, et al. Curr Osteoporos Rep. 2013 Mar;11(1):45-51. doi: 10.1007/s11914-012-0129-9. Curr Osteoporos Rep. 2013. PMID: 23296595 Free PMC article. Review.
The concept of a drug holiday has been proposed to potentially reduce incidence of these adverse events. ...As randomized clinical trial evidence is not yet available on who may qualify for drug holiday, this review will provide suggestions for clinici …
The concept of a drug holiday has been proposed to potentially reduce incidence of these adverse events. ...As randomized clin …
Effect of Oral Bisphosphonate Drug Holiday on Mortality Following Hip Fracture.
Leung MTY, Turner JP, Marquina C, Ilomaki J, Tran T, Bell JS. Leung MTY, et al. J Clin Endocrinol Metab. 2024 Oct 15;109(11):2793-2801. doi: 10.1210/clinem/dgae272. J Clin Endocrinol Metab. 2024. PMID: 38630464 Free PMC article.
CONTEXT: Current clinical guidelines recommend a drug holiday after extended use of oral bisphosphonates. However, no studies have investigated the effect of drug holidays before hip fractures on postfracture mortality. OBJECTIVE: This work aimed to in …
CONTEXT: Current clinical guidelines recommend a drug holiday after extended use of oral bisphosphonates. However, no s …
Italian position paper (SIPMO-SICMF) on medication-related osteonecrosis of the jaw (MRONJ).
Bedogni A, Mauceri R, Fusco V, Bertoldo F, Bettini G, Di Fede O, Lo Casto A, Marchetti C, Panzarella V, Saia G, Vescovi P, Campisi G. Bedogni A, et al. Oral Dis. 2024 Sep;30(6):3679-3709. doi: 10.1111/odi.14887. Epub 2024 Feb 5. Oral Dis. 2024. PMID: 38317291 Review.
CONCLUSION: The Expert Panel confirmed the MRONJ definition, the diagnostic work-up, the clinical-radiological staging system and the prophylactic drug holiday, as recognized by SIPMO-SICMF; while, it presented novel indications regarding the categories at risk of M …
CONCLUSION: The Expert Panel confirmed the MRONJ definition, the diagnostic work-up, the clinical-radiological staging system and the prophy …
Bisphosphonate therapy for osteoporosis: benefits, risks, and drug holiday.
McClung M, Harris ST, Miller PD, Bauer DC, Davison KS, Dian L, Hanley DA, Kendler DL, Yuen CK, Lewiecki EM. McClung M, et al. Am J Med. 2013 Jan;126(1):13-20. doi: 10.1016/j.amjmed.2012.06.023. Epub 2012 Nov 20. Am J Med. 2013. PMID: 23177553 Review.
Because bisphosphonates are incorporated into the skeleton and continue to exert an antiresorptive effect for a period of time after dosing is discontinued, the concept of a drug holiday has emerged, whereby the risk of adverse effects might be decreased whil …
Because bisphosphonates are incorporated into the skeleton and continue to exert an antiresorptive effect for a period of time after …
Drug holiday patterns and bisphosphonate-related osteonecrosis of the jaw.
Jung SY, Suh HS, Park JW, Kwon JW. Jung SY, et al. Oral Dis. 2019 Mar;25(2):471-480. doi: 10.1111/odi.12966. Epub 2018 Sep 17. Oral Dis. 2019. PMID: 30153366
OBJECTIVES: There is limited evidence regarding the appropriate length of a bisphosphonate (BP) holiday to reduce the risk of osteonecrosis of the jaw (ONJ). In this cross-sectional study, we investigated the population-based patterns of the gaps between BP disconti …
OBJECTIVES: There is limited evidence regarding the appropriate length of a bisphosphonate (BP) holiday to reduce the risk of …
Sequential and Long-term Therapy for Osteoporosis.
McClung MR. McClung MR. Curr Osteoporos Rep. 2025 Mar 22;23(1):15. doi: 10.1007/s11914-025-00909-2. Curr Osteoporos Rep. 2025. PMID: 40119973 Review.
This review highlights the important transitions among osteoporosis therapies and outlines a strategy of intermittent bisphosphonate therapy for long-term maintenance. RECENT FINDINGS: Over the past few years, the effects and limitations of long-term treatment with …
This review highlights the important transitions among osteoporosis therapies and outlines a strategy of intermittent bisphosphonate …
Medication-Related Osteonecrosis of the Jaw (MRONJ): A Review of Pathophysiology, Risk Factors, Preventive Measures and Treatment Strategies.
AlRowis R, Aldawood A, AlOtaibi M, Alnasser E, AlSaif I, Aljaber A, Natto Z. AlRowis R, et al. Saudi Dent J. 2022 Mar;34(3):202-210. doi: 10.1016/j.sdentj.2022.01.003. Epub 2022 Jan 19. Saudi Dent J. 2022. PMID: 35935720 Free PMC article. Review.
Medication-related osteonecrosis of the jaw (MRONJ) is a major problem that can occur in people taking certain medications such bisphosphonates and denosumab. It can be used to treat osteoporosis or cancer. Bisphosphonate exposure, dental diseases and procedures, ag …
Medication-related osteonecrosis of the jaw (MRONJ) is a major problem that can occur in people taking certain medications such bisphosph …
OSTEOPOROTIC FRACTURES DURING BISPHOSPHONATE DRUG HOLIDAY.
Bindon B, Adams W, Balasubramanian N, Sandhu J, Camacho P. Bindon B, et al. Endocr Pract. 2018 Feb;24(2):163-169. doi: 10.4158/EP171975.OR. Epub 2017 Nov 16. Endocr Pract. 2018. PMID: 29144808
Our aim was to determine the clinical and laboratory parameters associated with increased fracture risk in patients on BP drug holiday. METHODS: A retrospective chart review was conducted of 401 patients with osteopenia or osteoporosis who began a BP drug …
Our aim was to determine the clinical and laboratory parameters associated with increased fracture risk in patients on BP drug hol …
Bisphosphonate Treatment in Osteoporosis: Optimal Duration of Therapy and the Incorporation of a Drug Holiday.
Villa JC, Gianakos A, Lane JM. Villa JC, et al. HSS J. 2016 Feb;12(1):66-73. doi: 10.1007/s11420-015-9469-1. Epub 2015 Dec 9. HSS J. 2016. PMID: 26855630 Free PMC article. Review.
QUESTIONS/PURPOSES: The purpose of this study is to review the literature to determine the (1) indications for drug holiday, (2) the duration of drug holiday, (3) the evaluation during drug holiday, and (4) the proper treatment and …
QUESTIONS/PURPOSES: The purpose of this study is to review the literature to determine the (1) indications for drug holiday, ( …
249 results