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DNA barcode identification of black cohosh herbal dietary supplements.
Baker DA, Stevenson DW, Little DP. Baker DA, et al. J AOAC Int. 2012 Jul-Aug;95(4):1023-34. doi: 10.5740/jaoacint.11-261. J AOAC Int. 2012. PMID: 22970567
Accidental misidentification and/or deliberate adulteration results in harvesting other related species that are then marketed as black cohosh. ...None of the other Actaea species in the validation set were falsely identified as black cohosh. Of …
Accidental misidentification and/or deliberate adulteration results in harvesting other related species that are then marketed as …
Rapid high-performance thin-layer chromatographic method for detection of 5% adulteration of black cohosh with Cimicifuga foetida, C. heracleifolia, C. dahurica, or C. americana.
Ankli A, Reich E, Steiner M. Ankli A, et al. J AOAC Int. 2008 Nov-Dec;91(6):1257-64. J AOAC Int. 2008. PMID: 19202784
Black cohosh (Cimicifuga racemosa) is used to treat discomfort during menopause and as a substitute for synthetic drugs in hormone replacement therapy. ...It can be used for quality control of black cohosh raw material in a current Good Manufact …
Black cohosh (Cimicifuga racemosa) is used to treat discomfort during menopause and as a substitute for synthetic drugs …
Investigation of market herbal products regulated under different categories: How can HPTLC help to detect quality problems?
Frommenwiler DA, Reich E, Sharaf MHM, Cañigueral S, Etheridge CJ. Frommenwiler DA, et al. Front Pharmacol. 2022 Aug 8;13:925298. doi: 10.3389/fphar.2022.925298. eCollection 2022. Front Pharmacol. 2022. PMID: 36003516 Free PMC article.
A significant number of food supplements show quality issues (mainly adulterations): 52.4% of milk thistle, 33.3% of coneflower, and 45.5% of black cohosh products. The same was observed in 66.6% of black cohosh herbal drugs and preparations....
A significant number of food supplements show quality issues (mainly adulterations): 52.4% of milk thistle, 33.3% of coneflower, and …
One-class modeling for verification of botanical identity: a review.
Harnly J. Harnly J. Front Pharmacol. 2025 Mar 27;16:1504230. doi: 10.3389/fphar.2025.1504230. eCollection 2025. Front Pharmacol. 2025. PMID: 40213685 Free PMC article. Review.
Multivariate analysis is commonly used for identification, providing a broader coverage of the identity specifications of the samples. ...Examples are presented for the application of one-class modeling to identification of American ginseng (Panax quinquefolius), Ec …
Multivariate analysis is commonly used for identification, providing a broader coverage of the identity specifications of the samples …
Authentication of the botanical origin of Western herbal products using Cimicifuga and Vitex products as examples.
Masada S. Masada S. J Nat Med. 2016 Jul;70(3):361-75. doi: 10.1007/s11418-016-1006-0. Epub 2016 May 17. J Nat Med. 2016. PMID: 27188194 Free PMC article. Review.
This review describes studies on Cimicifuga and Vitex products developed in Europe and Japan, focusing on establishing analytical methods to evaluate the origins of material plants and finished products. ...A genome-based authentication method and liquid chromatography-mas …
This review describes studies on Cimicifuga and Vitex products developed in Europe and Japan, focusing on establishing analytical met …
Metabolic profiling of Actaea species extracts using high performance liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry.
Ma C, Kavalier AR, Jiang B, Kennelly EJ. Ma C, et al. J Chromatogr A. 2011 Mar 18;1218(11):1461-76. doi: 10.1016/j.chroma.2011.01.033. Epub 2011 Jan 19. J Chromatogr A. 2011. PMID: 21316686 Free PMC article.
Black cohosh products have been associated with cases of liver toxicity, but subsequent evaluation found some products to be adulterated with other related plants from the same genus. US FDA regulations require that black cohosh products be unad …
Black cohosh products have been associated with cases of liver toxicity, but subsequent evaluation found some products to be …
[Application of high resolution melting curve to identification of Cimicifugae Rhizoma].
Sun W, Xiong C, Li JJ, Liu HG, Hu ZG, Liu D, Ren WC, Chen SL. Sun W, et al. Yao Xue Xue Bao. 2016 Oct;51(10):1638-42. Yao Xue Xue Bao. 2016. PMID: 29932620 Chinese.
HRM assay was established for identification based on ITS2 region of Cimicifugae Rhizomas and its adulterants(including 41 samples). Our findings showed that HRM allows not only the identification of adulteration but also the quantification of the most …
HRM assay was established for identification based on ITS2 region of Cimicifugae Rhizomas and its adulterants(including 41 sam …
[Identification of cimicifugae rhizoma and its adulterants using ITS2 sequence].
Ren WC, Ma XX, Yu JL, Ma W, Sun W. Ren WC, et al. Zhongguo Zhong Yao Za Zhi. 2014 Jun;39(12):2184-8. Zhongguo Zhong Yao Za Zhi. 2014. PMID: 25244741 Chinese.
In order to identify Cimicifugae Rhizoma from its adulterants and to ensure its safe use, the internal transcribed spacer 2 (ITS2) sequence of Cimicifugae Rhizoma and its adulterants were amplified and bidirectionally sequenced by DNA barcoding technology. ...The ge …
In order to identify Cimicifugae Rhizoma from its adulterants and to ensure its safe use, the internal transcribed spacer 2 (ITS2) se …
Phytochemical fingerprinting to thwart black cohosh adulteration: a 15 Actaea species analysis.
Jiang B, Ma C, Motley T, Kronenberg F, Kennelly EJ. Jiang B, et al. Phytochem Anal. 2011 Jul-Aug;22(4):339-51. doi: 10.1002/pca.1285. Epub 2011 Feb 19. Phytochem Anal. 2011. PMID: 21337649
Correct plant species identification is a key first step for good manufacturing practices of safe black cohosh products. OBJECTIVES: To develop analytical methods which distinguish black cohosh from other species (American and Asian) of Actaea i …
Correct plant species identification is a key first step for good manufacturing practices of safe black cohosh products …