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Page 1
Melanocytes Sense Blue Light and Regulate Pigmentation through Opsin-3.
Regazzetti C, Sormani L, Debayle D, Bernerd F, Tulic MK, De Donatis GM, Chignon-Sicard B, Rocchi S, Passeron T. Regazzetti C, et al. J Invest Dermatol. 2018 Jan;138(1):171-178. doi: 10.1016/j.jid.2017.07.833. Epub 2017 Aug 24. J Invest Dermatol. 2018. PMID: 28842328 Free article.
This multimeric tyrosinase/tyrosinase-related protein complex is mainly formed in dark-skinned melanocytes and induces a sustained tyrosinase activity, thus explaining the long-lasting hyperpigmentation that is observed only in skin type III and higher after blue
This multimeric tyrosinase/tyrosinase-related protein complex is mainly formed in dark-skinned melanocytes and induces a sustained ty …
The Pigmentation of Blue Light Is Mediated by Both Melanogenesis Activation and Autophagy Inhibition through OPN3-TRPV1.
Yu E, Oh SW, Park SH, Kwon K, Han SB, Kang SH, Lee JH, Ha H, Yoon D, Jung E, Song M, Cho JY, Lee J. Yu E, et al. J Invest Dermatol. 2025 Apr;145(4):908-918.e6. doi: 10.1016/j.jid.2024.07.034. Epub 2024 Sep 4. J Invest Dermatol. 2025. PMID: 39241981 Free article.
Blue light, a high-energy radiation in the visible light spectrum, was recently reported to induce skin pigmentation. ...Furthermore, these results suggest that TRPV1 and clusterin could be potential therapeutic targets for blue light
Blue light, a high-energy radiation in the visible light spectrum, was recently reported to induce skin pigme
The Aqueous Extract of Polypodium leucotomos (Fernblock( )) Regulates Opsin 3 and Prevents Photooxidation of Melanin Precursors on Skin Cells Exposed to Blue Light Emitted from Digital Devices.
Portillo M, Mataix M, Alonso-Juarranz M, Lorrio S, Villalba M, Rodríguez-Luna A, González S. Portillo M, et al. Antioxidants (Basel). 2021 Mar 6;10(3):400. doi: 10.3390/antiox10030400. Antioxidants (Basel). 2021. PMID: 33800784 Free PMC article.
The effects of sun exposure on the skin and specifically those related to pigmentation disorders are well known. It has recently been shown that blue light leads to the induction of oxidative stress and long-lasting pigmentation. ...Our aim was …
The effects of sun exposure on the skin and specifically those related to pigmentation disorders are well known. It has recent …
The regulation of skin pigmentation in response to environmental light by pineal Type II opsins and skin melanophore melatonin receptors.
Bertolesi GE, Atkinson-Leadbeater K, Mackey EM, Song YN, Heyne B, McFarlane S. Bertolesi GE, et al. J Photochem Photobiol B. 2020 Nov;212:112024. doi: 10.1016/j.jphotobiol.2020.112024. Epub 2020 Sep 11. J Photochem Photobiol B. 2020. PMID: 32957069
These genes were grouped into subfamilies based on their predicted amino acid sequences and the presence of specific amino acids essential for their function. The pineal complex expresses mainly blue light sensitive opsins [pinopsin, parietopsin, opn3, and me …
These genes were grouped into subfamilies based on their predicted amino acid sequences and the presence of specific amino acids essential f …
Sws2 Gene Positively Regulates Melanin Production in Plectropomus leopardus Skin via Direct Regulation of the Synthesis of Retinoic Acid.
Yu H, Chen H, Wang X, Zhang Y, Tan Y, Wang L, Sun J, Luo J, Song F. Yu H, et al. Int J Mol Sci. 2024 Jul 9;25(14):7513. doi: 10.3390/ijms25147513. Int J Mol Sci. 2024. PMID: 39062755 Free PMC article.
Opsins are a class of transmembrane proteins encoded by opsin genes, and they play a variety of functional roles. Short wavelength-sensitive opsin 2 (sws2), one of the five classes of visual opsin genes, mainly senses blue light. ...
Opsins are a class of transmembrane proteins encoded by opsin genes, and they play a variety of functional roles. Short wavele
From extraocular photoreception to pigment movement regulation: a new control mechanism of the lanternshark luminescence.
Duchatelet L, Sugihara T, Delroisse J, Koyanagi M, Rezsohazy R, Terakita A, Mallefet J. Duchatelet L, et al. Sci Rep. 2020 Jun 23;10(1):10195. doi: 10.1038/s41598-020-67287-w. Sci Rep. 2020. PMID: 32576969 Free PMC article.
The velvet belly lanternshark, Etmopterus spinax, uses counterillumination to disappear in the surrounding blue light of its marine environment. This shark displays hormonally controlled bioluminescence in which melatonin (MT) and prolactin (PRL) trigger light
The velvet belly lanternshark, Etmopterus spinax, uses counterillumination to disappear in the surrounding blue light of its m …