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Up-regulatory impact of boron on vitamin D function -- does it reflect inhibition of 24-hydroxylase?
Miljkovic D, Miljkovic N, McCarty MF. Miljkovic D, et al. Med Hypotheses. 2004;63(6):1054-6. doi: 10.1016/j.mehy.2003.12.053. Med Hypotheses. 2004. PMID: 15504575
This inhibition may reflect a direct interaction with the enzyme, or perhaps boron's ability to form a covalent complex with the product of its activity, 24,25-dihydroxyvitamin D. ...There is growing evidence that good vitamin D status -- …
This inhibition may reflect a direct interaction with the enzyme, or perhaps boron's ability to form a covalent complex with t …
Development of a biologically active fluorescent-labeled calcitriol and its use to study hormone binding to the vitamin D receptor.
Barsony J, Renyi I, McKoy W, Kang HC, Haugland RP, Smith CL. Barsony J, et al. Anal Biochem. 1995 Jul 20;229(1):68-79. doi: 10.1006/abio.1995.1380. Anal Biochem. 1995. PMID: 8533897
To gain better insight into the mechanism of steroid receptor activation and calcitriol action, we have developed the first pharmacologically relevant fluorescent-labeled ligand for the vitamin D receptor (VDR). Purity and structure of three BODIPY-labeled ca …
To gain better insight into the mechanism of steroid receptor activation and calcitriol action, we have developed the first pharmacol …