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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1983 4
1984 6
1985 7
1986 25
1987 13
1988 23
1989 34
1990 36
1991 36
1992 36
1993 47
1994 41
1995 41
1996 36
1997 38
1998 50
1999 42
2000 37
2001 42
2002 36
2003 24
2004 29
2005 29
2006 35
2007 41
2008 46
2009 24
2010 35
2011 31
2012 21
2013 24
2014 30
2015 32
2016 21
2017 25
2018 25
2019 30
2020 25
2021 24
2022 11
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1,144 results
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Page 1
Diagnosis and treatment of Lyme arthritis.
Arvikar SL, Steere AC. Arvikar SL, et al. Infect Dis Clin North Am. 2015 Jun;29(2):269-80. doi: 10.1016/j.idc.2015.02.004. Infect Dis Clin North Am. 2015. PMID: 25999223 Free PMC article. Review.
In the United States, Lyme arthritis is the most common feature of late-stage Borrelia burgdorferi infection, usually beginning months after the initial bite. In some, earlier phases are asymptomatic and arthritis is the presenting manifestation. Patients wit …
In the United States, Lyme arthritis is the most common feature of late-stage Borrelia burgdorferi infection, usually beginnin …
Lyme arthritis: linking infection, inflammation and autoimmunity.
Lochhead RB, Strle K, Arvikar SL, Weis JJ, Steere AC. Lochhead RB, et al. Nat Rev Rheumatol. 2021 Aug;17(8):449-461. doi: 10.1038/s41584-021-00648-5. Epub 2021 Jul 5. Nat Rev Rheumatol. 2021. PMID: 34226730 Review.
Infectious agents can trigger autoimmune responses in a number of chronic inflammatory diseases. Lyme arthritis, which is caused by the tick-transmitted spirochaete Borrelia burgdorferi, is effectively treated in most patients with antibiotic therapy; however, in a …
Infectious agents can trigger autoimmune responses in a number of chronic inflammatory diseases. Lyme arthritis, which is caused by t …
Septic Arthritis: Diagnosis and Treatment.
Earwood JS, Walker TR, Sue GJC. Earwood JS, et al. Am Fam Physician. 2021 Dec 1;104(6):589-597. Am Fam Physician. 2021. PMID: 34913662
Septic arthritis must be considered and promptly diagnosed in any patient presenting with acute atraumatic joint pain, swelling, and fever. Risk factors for septic arthritis include age older than 80 years, diabetes mellitus, rheumatoid arthritis, recent join …
Septic arthritis must be considered and promptly diagnosed in any patient presenting with acute atraumatic joint pain, swelling, and …
Lyme borreliosis.
Steere AC, Strle F, Wormser GP, Hu LT, Branda JA, Hovius JW, Li X, Mead PS. Steere AC, et al. Nat Rev Dis Primers. 2016 Dec 15;2:16090. doi: 10.1038/nrdp.2016.90. Nat Rev Dis Primers. 2016. PMID: 27976670 Free PMC article. Review.
Lyme borreliosis is a tick-borne disease that predominantly occurs in temperate regions of the northern hemisphere and is primarily caused by the bacterium Borrelia burgdorferi in North America and Borrelia afzelii or Borrelia garinii in Europe and Asia. Infe …
Lyme borreliosis is a tick-borne disease that predominantly occurs in temperate regions of the northern hemisphere and is primarily caused b …
Clinical spectrum of Lyme disease.
Cardenas-de la Garza JA, De la Cruz-Valadez E, Ocampo-Candiani J, Welsh O. Cardenas-de la Garza JA, et al. Eur J Clin Microbiol Infect Dis. 2019 Feb;38(2):201-208. doi: 10.1007/s10096-018-3417-1. Epub 2018 Nov 19. Eur J Clin Microbiol Infect Dis. 2019. PMID: 30456435 Review.
Its incidence and geographic expansion has been steadily increasing in the last decades. Lyme disease is caused by Borrelia burgdorferi sensu lato, a heterogeneous group of which three genospecies have been systematically associated to Lyme disease: B. burgdorferi sensu st …
Its incidence and geographic expansion has been steadily increasing in the last decades. Lyme disease is caused by Borrelia burgdorfe …
Lyme borreliosis: diagnosis and management.
Kullberg BJ, Vrijmoeth HD, van de Schoor F, Hovius JW. Kullberg BJ, et al. BMJ. 2020 May 26;369:m1041. doi: 10.1136/bmj.m1041. BMJ. 2020. PMID: 32457042 Review.
It usually begins with erythema migrans; early disseminated infection particularly causes multiple erythema migrans or neurologic disease, and late manifestations predominantly include arthritis in North America, and acrodermatitis chronica atrophicans (ACA) in Europe. ... …
It usually begins with erythema migrans; early disseminated infection particularly causes multiple erythema migrans or neurologic disease, a …
Tick borne illness-Lyme disease.
Bush LM, Vazquez-Pertejo MT. Bush LM, et al. Dis Mon. 2018 May;64(5):195-212. doi: 10.1016/j.disamonth.2018.01.007. Dis Mon. 2018. PMID: 29402399 Review.
Lyme disease is the most commonly reported tick-borneillness in the United States. Thecausative spirochete, Borrelia burgdorferi is transmitted by 4 species of Ixodes tick species. ...Signs and symptomsof infection occur in 3 stages; early localized, typified by erythema m …
Lyme disease is the most commonly reported tick-borneillness in the United States. Thecausative spirochete, Borrelia burgdorferi is t …
Arthritis is developed in Borrelia-primed and -infected mice deficient of interleukin-17.
Kuo J, Warner TF, Munson EL, Nardelli DT, Schell RF. Kuo J, et al. Pathog Dis. 2016 Oct;74(7):ftw077. doi: 10.1093/femspd/ftw077. Epub 2016 Aug 4. Pathog Dis. 2016. PMID: 27493062
Interleukin-17 (IL-17) has been shown to participate in the development of Lyme arthritis in experimental mice. For example, neutralization of IL-17 with antibodies inhibits induction of arthritis in Borrelia-primed and -infected C57BL/6 wild-type mice. We hy …
Interleukin-17 (IL-17) has been shown to participate in the development of Lyme arthritis in experimental mice. For example, neutrali …
Borrelia-primed and -infected mice deficient of interleukin-17 develop arthritis after neutralization of gamma-interferon.
Kuo J, Warner TF, Schell RF. Kuo J, et al. Pathog Dis. 2017 Mar 1;75(2). doi: 10.1093/femspd/ftx014. Pathog Dis. 2017. PMID: 28175297
Elevated levels of IL-17 and/or IFN-gamma have been reported in samples from human Lyme arthritis patients and experimental mice. In addition, IL-17 and IFN-gamma have been implicated in the onset of arthritis in Borrelia-primed and -infected C57BL/6 mice. .. …
Elevated levels of IL-17 and/or IFN-gamma have been reported in samples from human Lyme arthritis patients and experimental mice. In …
The Borrelia burgdorferi VlsE Lipoprotein Prevents Antibody Binding to an Arthritis-Related Surface Antigen.
Lone AG, Bankhead T. Lone AG, et al. Cell Rep. 2020 Mar 17;30(11):3663-3670.e5. doi: 10.1016/j.celrep.2020.02.081. Cell Rep. 2020. PMID: 32187539 Free PMC article.
Arp is an immunogenic protein of the Lyme disease spirochete Borrelia burgdorferi and contributes to joint inflammation during infection. ...
Arp is an immunogenic protein of the Lyme disease spirochete Borrelia burgdorferi and contributes to joint inflammation during infect …
1,144 results