Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2004 1
2005 1
2012 1
2013 1
2015 2
2016 1
2019 1
2020 1
2022 1
2023 1
2024 1

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

11 results

Results by year

Filters applied: . Clear all
Page 1
Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells.
Liu JJ, Nilsson A, Oredsson S, Badmaev V, Zhao WZ, Duan RD. Liu JJ, et al. Carcinogenesis. 2002 Dec;23(12):2087-93. doi: 10.1093/carcin/23.12.2087. Carcinogenesis. 2002. PMID: 12507932
We studied their antiproliferative and apoptotic effects on colon cancer cells and the pathway leading to apoptosis. HT-29 cells were treated with beta-boswellic acid (BA), keto-beta-boswellic acid (K-BA) and acetyl-keto-beta-boswellic …
We studied their antiproliferative and apoptotic effects on colon cancer cells and the pathway leading to apoptosis. HT-29 cells were …
Recent Advances Regarding the Molecular Mechanisms of Triterpenic Acids: A Review (Part II).
Mioc M, Prodea A, Racoviceanu R, Mioc A, Ghiulai R, Milan A, Voicu M, Mardale G, Șoica C. Mioc M, et al. Int J Mol Sci. 2022 Aug 10;23(16):8896. doi: 10.3390/ijms23168896. Int J Mol Sci. 2022. PMID: 36012159 Free PMC article. Review.
The current paper aimed to summarize the most recent (last 5 years) studies regarding the MOA of betulinic acid, boswellic acid, glycyrrhetinic acid, madecassic acid, moronic acid, and pomolic acid in order to provide scientists with updated and accessible material …
The current paper aimed to summarize the most recent (last 5 years) studies regarding the MOA of betulinic acid, boswellic acid …
Triggering of Suicidal Erythrocyte Death Following Boswellic Acid Exposure.
Calabrò S, Alzoubi K, Faggio C, Laufer S, Lang F. Calabrò S, et al. Cell Physiol Biochem. 2015;37(1):131-42. doi: 10.1159/000430339. Epub 2015 Aug 17. Cell Physiol Biochem. 2015. PMID: 26303375 Free article.
BACKGROUND/AIMS: The antinflammatory natural product boswellic acid is effective against cancer at least in part by inducing tumor cell apoptosis. ...Boswellic acid did not significantly modify [Ca(2+)]i, cytosolic ATP, ROS, or ceramide abundanc …
BACKGROUND/AIMS: The antinflammatory natural product boswellic acid is effective against cancer at least in part by inducing t …
Boswellic acid disables signal transduction of IL-6-STAT-3 in Ehrlich ascites tumor bearing irradiated mice.
Moustafa EM, Thabet NM, Azab KS. Moustafa EM, et al. Biochem Cell Biol. 2016 Aug;94(4):307-13. doi: 10.1139/bcb-2015-0169. Epub 2016 Mar 22. Biochem Cell Biol. 2016. PMID: 27458759
Boswellic acid (BA) is known for its ability to trigger apoptosis as well as to inhibit angiogenesis in tumor tissue. ...We propose that BA interfered with IL-6-STAT-3 signal transduction, thereby preventing the activation of caspase-3 and subsequently …
Boswellic acid (BA) is known for its ability to trigger apoptosis as well as to inhibit angiogenesis in tumor ti …
Pegylated polymeric micelles of boswellic acid-selenium mitigates repetitive mild traumatic brain injury: Regulation of miR-155 and miR-146a/BDNF/ Klotho/Foxo3a cue.
El-Gazar AA, El-Emam SZ, M El-Sayyad S, El-Mancy SS, Fayez SM, Sheta NM, Al-Mokaddem AK, Ragab GM. El-Gazar AA, et al. Int Immunopharmacol. 2024 Jun 15;134:112118. doi: 10.1016/j.intimp.2024.112118. Epub 2024 May 4. Int Immunopharmacol. 2024. PMID: 38705029
This study aims to explore the protective machinery of pegylated polymeric micelles of boswellic acid-selenium (PMBS) against secondary neuronal damage triggered by mild repetitive traumatic brain injury (RTBI). ...Groups 2 was RTBI positive control, while 3, …
This study aims to explore the protective machinery of pegylated polymeric micelles of boswellic acid-selenium (PMBS) against …
Antiproliferative and cell cycle arrest potentials of 3-O-acetyl-11-keto-beta-boswellic acid against MCF-7 cells in vitro.
Ahmed SA, Al-Shanon AF, Al-Saffar AZ, Tawang A, Al-Obaidi JR. Ahmed SA, et al. J Genet Eng Biotechnol. 2023 Jul 2;21(1):75. doi: 10.1186/s43141-023-00529-2. J Genet Eng Biotechnol. 2023. PMID: 37393563 Free PMC article.
Therefore, searching for alternatives and nonorthodox methods of treatments with high efficiency, selectivity and less toxicity is the main goal in fighting cancer. Acetyl-11-keto-beta-boswellic acid (AKBA), is a derivative pentacyclic triterpenoid that exhibited va …
Therefore, searching for alternatives and nonorthodox methods of treatments with high efficiency, selectivity and less toxicity is the main …
[Boswellic acids (components of frankincense) as the active principle in treatment of chronic inflammatory diseases].
Ammon HP. Ammon HP. Wien Med Wochenschr. 2002;152(15-16):373-8. doi: 10.1046/j.1563-258x.2002.02056.x. Wien Med Wochenschr. 2002. PMID: 12244881 Review. German.
Compounds from the gum with genuine antiinflammatory effects are pentacyclic triterpenes of the boswellic acid type. Boswellic acids inhibit the leukotriene biosynthesis in neutrophilic granulocytes by a non-redox, noncompetitive inhibition of 5-lipoxygenase. The ef …
Compounds from the gum with genuine antiinflammatory effects are pentacyclic triterpenes of the boswellic acid type. Boswellic …
Acetyl-11-keto-beta-boswellic acid triggers premature senescence via induction of DNA damage accompanied by impairment of DNA repair genes in hepatocellular carcinoma cells in vitro and in vivo.
Wang S, Wang H, Sun B, Li D, Wu J, Li J, Tian X, Qin C, Chang H, Liu Y. Wang S, et al. Fundam Clin Pharmacol. 2020 Feb;34(1):65-76. doi: 10.1111/fcp.12488. Epub 2019 Jun 26. Fundam Clin Pharmacol. 2020. PMID: 31141202
Recently, cellular senescence has been emerging as one of the principal mechanisms of tumor suppression, which can be induced by low doses of therapeutic drugs in cancer cells. Acetyl-11-keto-beta-boswellic acid (AKBA), an active ingredient isolated from the plant B …
Recently, cellular senescence has been emerging as one of the principal mechanisms of tumor suppression, which can be induced by low doses o …
Inhibition of IkappaB kinase activity by acetyl-boswellic acids promotes apoptosis in androgen-independent PC-3 prostate cancer cells in vitro and in vivo.
Syrovets T, Gschwend JE, Büchele B, Laumonnier Y, Zugmaier W, Genze F, Simmet T. Syrovets T, et al. J Biol Chem. 2005 Feb 18;280(7):6170-80. doi: 10.1074/jbc.M409477200. Epub 2004 Dec 2. J Biol Chem. 2005. PMID: 15576374 Free article.
Here we show that the natural compounds acetyl-beta-boswellic acid and acetyl-11-keto-beta-boswellic acid (AKbetaBA) inhibit proliferation and elicit cell death in chemoresistant androgen-independent PC-3 prostate cancer cells in vitro and in vivo. ... …
Here we show that the natural compounds acetyl-beta-boswellic acid and acetyl-11-keto-beta-boswellic acid (AKbet …
A novel semisynthetic inhibitor of the FRB domain of mammalian target of rapamycin blocks proliferation and triggers apoptosis in chemoresistant prostate cancer cells.
Morad SA, Schmid M, Büchele B, Siehl HU, El Gafaary M, Lunov O, Syrovets T, Simmet T. Morad SA, et al. Mol Pharmacol. 2013 Feb;83(2):531-41. doi: 10.1124/mol.112.081349. Epub 2012 Dec 3. Mol Pharmacol. 2013. PMID: 23208958
We synthesized and chemically characterized a novel, semisynthetic triterpenoid derivative, 3-cinnamoyl-11-keto-beta-boswellic acid (C-KbetaBA). Its pharmacodynamic effects on mTOR and several other signaling pathways were assessed in a number of prostate and breast …
We synthesized and chemically characterized a novel, semisynthetic triterpenoid derivative, 3-cinnamoyl-11-keto-beta-boswellic aci …
11 results