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HIV broadly neutralizing antibody escape dynamics drive the outcome of AAV vectored immunotherapy in humanized mice.
Galvez NMS, Nitido AD, Yoo SB, Cao Y, Deal CE, Boutros CL, MacDonald SW, Albrecht YES, Lam EC, Sheehan ML, Parsons D, Lin AZ, Deymier MJ, Brady JM, Moon B, Bullock CB, Tanno S, Pegu A, Chen X, Liu C, Koup RA, Mascola JR, Vrbanac VD, Lingwood D, Balazs AB. Galvez NMS, et al. Among authors: boutros cl, balazs ab. bioRxiv [Preprint]. 2025 Jun 14:2024.07.11.603156. doi: 10.1101/2024.07.11.603156. bioRxiv. 2025. PMID: 39026699 Free PMC article. Preprint.
Antibody-mediated prevention of vaginal HIV transmission is dictated by IgG subclass in humanized mice.
Brady JM, Phelps M, MacDonald SW, Lam EC, Nitido A, Parsons D, Boutros CL, Deal CE, Garcia-Beltran WF, Tanno S, Natarajan H, Ackerman ME, Vrbanac VD, Balazs AB. Brady JM, et al. Among authors: boutros cl, balazs ab. Sci Transl Med. 2022 Jul 27;14(655):eabn9662. doi: 10.1126/scitranslmed.abn9662. Epub 2022 Jul 27. Sci Transl Med. 2022. PMID: 35895834 Free PMC article.