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Hair cell ribbon synapses.
Moser T, Brandt A, Lysakowski A. Moser T, et al. Among authors: brandt a. Cell Tissue Res. 2006 Nov;326(2):347-59. doi: 10.1007/s00441-006-0276-3. Epub 2006 Aug 31. Cell Tissue Res. 2006. PMID: 16944206 Free PMC article. Review.
Hearing and balance rely on the faithful synaptic coding of mechanical input by the auditory and vestibular hair cells of the inner ear. Mechanical deflection of their stereocilia causes the opening of mechanosensitive channels, resulting in hair ce
Hearing and balance rely on the faithful synaptic coding of mechanical input by the auditory and vestibular hair cells
Few CaV1.3 channels regulate the exocytosis of a synaptic vesicle at the hair cell ribbon synapse.
Brandt A, Khimich D, Moser T. Brandt A, et al. J Neurosci. 2005 Dec 14;25(50):11577-85. doi: 10.1523/JNEUROSCI.3411-05.2005. J Neurosci. 2005. PMID: 16354915 Free PMC article.
Hearing relies on faithful sound coding at hair cell ribbon synapses, which use Ca2+-triggered glutamate release to signal with submillisecond precision. Here, we investigated stimulus-secretion coupling at mammalian inner hair cell (IHC) synapses to e …
Hearing relies on faithful sound coding at hair cell ribbon synapses, which use Ca2+-triggered glutamate release to signal wit …
[Update on physiology and pathophysiology of the inner ear: pathomechanisms of sensorineural hearing loss].
Strenzke N, Pauli-Magnus D, Meyer A, Brandt A, Maier H, Moser T. Strenzke N, et al. Among authors: brandt a. HNO. 2008 Jan;56(1):27-36. doi: 10.1007/s00106-007-1640-7. HNO. 2008. PMID: 18210004 Review. German.
First, insights gained from models for specific defects in cochlear sound amplification and ion homeostasis are discussed followed by a focus on disorders of the inner hair cell synapses (auditory synaptopathy) and the auditory nerve (auditory n …
First, insights gained from models for specific defects in cochlear sound amplification and ion homeostasis are discussed followed by a focu …
CaV1.3 channels are essential for development and presynaptic activity of cochlear inner hair cells.
Brandt A, Striessnig J, Moser T. Brandt A, et al. J Neurosci. 2003 Nov 26;23(34):10832-40. doi: 10.1523/JNEUROSCI.23-34-10832.2003. J Neurosci. 2003. PMID: 14645476 Free PMC article.
Cochlear inner hair cells (IHCs) release neurotransmitter onto afferent auditory nerve fibers in response to sound stimulation. ...Most strikingly, we observed a continued presence of efferent cholinergic synaptic transmission and a lack of functional large-c …
Cochlear inner hair cells (IHCs) release neurotransmitter onto afferent auditory nerve fibers in response to sound stim …