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High cortisol awakening response is associated with an impairment of the effect of bright light therapy.
Martiny K, Lunde M, Undén M, Dam H, Bech P. Martiny K, et al. Acta Psychiatr Scand. 2009 Sep;120(3):196-202. doi: 10.1111/j.1600-0447.2009.01359.x. Epub 2009 Feb 12. Acta Psychiatr Scand. 2009. PMID: 19222404 Clinical Trial.
OBJECTIVE: We investigated the predictive validity of the cortisol awakening response (CAR) in patients with non-seasonal major depression. METHOD: Patients were treated with sertraline in combination with bright or dim light therapy for a 5-wee …
OBJECTIVE: We investigated the predictive validity of the cortisol awakening response (CAR) in patients with non-season …
The effects of post-awakening light exposure on the cortisol awakening response in healthy male individuals.
Petrowski K, Schmalbach B, Niedling M, Stalder T. Petrowski K, et al. Psychoneuroendocrinology. 2019 Oct;108:28-34. doi: 10.1016/j.psyneuen.2019.05.016. Epub 2019 May 17. Psychoneuroendocrinology. 2019. PMID: 31220690
BACKGROUND: It is assumed that the expression of the cortisol awakening response (CAR) is modulated by light exposure during the peri-awakening period. While initial evidence supports this principal effect, the specific role of the spectral comp …
BACKGROUND: It is assumed that the expression of the cortisol awakening response (CAR) is modulated by light exp …
The effects of light exposure on the cortisol stress response in human males.
Petrowski K, Buehrer S, Niedling M, Schmalbach B. Petrowski K, et al. Stress. 2021 Jan;24(1):29-35. doi: 10.1080/10253890.2020.1741543. Epub 2020 Apr 6. Stress. 2021. PMID: 32160826 Free article. Clinical Trial.
It is assumed that the production of cortisol is modulated by light exposure. While initial evidence supports this principal effect, the specific effect of light (intensity and wavelength) onto the cortisol stress response is still not completel …
It is assumed that the production of cortisol is modulated by light exposure. While initial evidence supports this principal e …
Cortisol awakening response in pregnant women with depressive disorders: a potential marker of recovery status from pregnancy to postpartum.
Broeks CW, Bais B, Van R, Bijma HH, van Rossum EFC, Hoogendijk WJG, Lambregtse-Van den Berg MP, Kamperman AM. Broeks CW, et al. Compr Psychoneuroendocrinol. 2025 Apr 28;23:100297. doi: 10.1016/j.cpnec.2025.100297. eCollection 2025 Aug. Compr Psychoneuroendocrinol. 2025. PMID: 40416950 Free PMC article.
This study examines the relationship between the cortisol awakening response (CAR) during pregnancy and depressive symptom reduction postpartum. ...CONCLUSION: Higher AUCi and peak cortisol reactivity of the cortisol awakening response
This study examines the relationship between the cortisol awakening response (CAR) during pregnancy and depressive symp …
The effect of dawn simulation on the cortisol response to awakening in healthy participants.
Thorn L, Hucklebridge F, Esgate A, Evans P, Clow A. Thorn L, et al. Psychoneuroendocrinology. 2004 Aug;29(7):925-30. doi: 10.1016/j.psyneuen.2003.08.005. Psychoneuroendocrinology. 2004. PMID: 15177708 Clinical Trial.
Bright light exposure after awakening has been shown to elevate cortisol levels in healthy participants. ...Participants also reported greater arousal in the experimental condition and there was a trend for an association between increased arousal and
Bright light exposure after awakening has been shown to elevate cortisol levels in healthy participants. ...Part
Increase in cortisol concentration due to standardized bright and blue light exposure on saliva cortisol in the morning following sleep laboratory.
Petrowski K, Bührer S, Albus C, Schmalbach B. Petrowski K, et al. Stress. 2021 May;24(3):331-337. doi: 10.1080/10253890.2020.1803265. Epub 2020 Aug 10. Stress. 2021. PMID: 32723201 Free article. Clinical Trial.
Results from repeated measures ANOVA confirm that light exposure affects the cortisol concentration. Study 1 revealed an increase in the saliva cortisol concentration after bright light exposure compared to dim light. ...This study shows …
Results from repeated measures ANOVA confirm that light exposure affects the cortisol concentration. Study 1 revealed an incre …
The influence of light on Interleukin-10: A preliminary study.
Mekschrat L, Göring M, Schmalbach B, Rohleder N, Petrowski K. Mekschrat L, et al. Brain Behav Immun Health. 2024 Oct 6;42:100887. doi: 10.1016/j.bbih.2024.100887. eCollection 2024 Dec. Brain Behav Immun Health. 2024. PMID: 39435315 Free PMC article.
In a between-subject design, N = 42 participants were exposed to either bright, dim, blue or red light after wake-up. Two mixed-model analyses with the factors of light condition and time (across eight IL-10 and cortisol sampling points) were conducted …
In a between-subject design, N = 42 participants were exposed to either bright, dim, blue or red light after wake-up. Two mixe …
The normalization of the cortisol awakening response and of the cortisol shift profile across consecutive night shifts--an experimental study.
Griefahn B, Robens S. Griefahn B, et al. Psychoneuroendocrinology. 2010 Nov;35(10):1501-9. doi: 10.1016/j.psyneuen.2010.05.002. Epub 2010 Jun 8. Psychoneuroendocrinology. 2010. PMID: 20570446
This study tested the hypothesis that the cortisol awakening response (CAR) and the cortisol shift profile normalize with successive night shifts due to the shift of the circadian system. 18 students (9 women, 9 men, 19-29 years), worked first four con …
This study tested the hypothesis that the cortisol awakening response (CAR) and the cortisol shift profile norma …
Novel Augmentation Strategies in Major Depression.
Martiny K. Martiny K. Dan Med J. 2017 Apr;64(4):B5338. Dan Med J. 2017. PMID: 28385173 Free article. Review.
Results from the Bright Light study Analysis of the saliva cortisol measurements taken at baseline of the study as cortisol awakening profiles (CAR) showed that patients responded differentially to light treatment according to their CAR l …
Results from the Bright Light study Analysis of the saliva cortisol measurements taken at baseline of the study as c
The inflammatory immune system after wake up in healthy male individuals: A highly standardized and controlled study.
Petrowski K, Schmalbach B, Linhardt M, Mekschrat L, Rohleder N. Petrowski K, et al. Brain Behav Immun Health. 2022 Aug 28;25:100504. doi: 10.1016/j.bbih.2022.100504. eCollection 2022 Nov. Brain Behav Immun Health. 2022. PMID: 36093437 Free PMC article.
This study investigates the effects of two light conditions on innate proinflammatory IL-6 cytokines and the cortisol awakening response. ...Cortisol significantly increased with bright light exposure as compared to dim light
This study investigates the effects of two light conditions on innate proinflammatory IL-6 cytokines and the cortisol awake