Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation.
Elliott KH, Balchand SK, Bonatto Paese CL, Chang CF, Yang Y, Brown KM, Rasicci DT, He H, Thorner K, Chaturvedi P, Murray SA, Chen J, Porollo A, Peterson KA, Brugmann SA.
Elliott KH, et al. Among authors: brugmann sa.
Development. 2023 Apr 15;150(8):dev201237. doi: 10.1242/dev.201237. Epub 2023 Apr 27.
Development. 2023.
PMID: 36971348
Free PMC article.
Primary cilia are nearly ubiquitous organelles that transduce molecular and mechanical signals. ...The biological relevance of ciliary heterogeneity was functionally validated by using Cas9 gene-editing to disrupt ciliary genes that displayed dynamic gene expression profil …
Primary cilia are nearly ubiquitous organelles that transduce molecular and mechanical signals. ...The biological relevance of ciliar …