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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 2
1970 4
1971 1
1973 2
1974 4
1975 7
1976 5
1977 1
1978 6
1979 10
1980 9
1981 10
1982 19
1983 23
1984 21
1985 24
1986 34
1987 41
1988 57
1989 81
1990 110
1991 106
1992 123
1993 126
1994 138
1995 141
1996 150
1997 167
1998 200
1999 162
2000 181
2001 149
2002 149
2003 182
2004 181
2005 201
2006 164
2007 170
2008 181
2009 215
2010 185
2011 186
2012 192
2013 189
2014 204
2015 199
2016 185
2017 187
2018 179
2019 154
2020 167
2021 151
2022 160
2023 146
2024 134
2025 65

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5,768 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Perineural Liposomal Bupivacaine Is Not Superior to Nonliposomal Bupivacaine for Peripheral Nerve Block Analgesia.
Hussain N, Brull R, Sheehy B, Essandoh MK, Stahl DL, Weaver TE, Abdallah FW. Hussain N, et al. Anesthesiology. 2021 Feb 1;134(2):147-164. doi: 10.1097/ALN.0000000000003651. Anesthesiology. 2021. PMID: 33372953
When all trials were pooled, AUC pain scores SD at 24 to 72 h were 7.6 4.9 cm . h and 6.6 4.6 cm . h for nonliposomal and liposomal bupivacaine, respectively. As such, perineural liposomal bupivacaine provided a clinically unimportant benefit by improving the AUC (9 …
When all trials were pooled, AUC pain scores SD at 24 to 72 h were 7.6 4.9 cm . h and 6.6 4.6 cm . h for nonliposomal and liposomal bupiv …
Epidural ropivacaine versus bupivacaine for cesarean sections: a system review and meta-analysis.
Kang T, Tao J, Wang X, Liu Y, Jin D. Kang T, et al. J Matern Fetal Neonatal Med. 2024 Dec;37(1):2313356. doi: 10.1080/14767058.2024.2313356. Epub 2024 Feb 11. J Matern Fetal Neonatal Med. 2024. PMID: 38342577 Free article. Review.
This system review and meta-analysis aimed to compare the efficacy of epidural ropivacaine and bupivacaine for elective CSs and investigate relative complications for parturients and neonates. ...RESULTS: We analyzed 8 RCTs with 532 parturients. 0.75% ropivacaine is associ …
This system review and meta-analysis aimed to compare the efficacy of epidural ropivacaine and bupivacaine for elective CSs and inves …
Efficacy of liposomal bupivacaine vs. traditional anaesthetic infiltration for pain management in total hip arthroplasty: a systematic review and meta-analysis.
Zhou SC, Liu BG, Wang ZH. Zhou SC, et al. Eur Rev Med Pharmacol Sci. 2020 Nov;24(21):11305-11314. doi: 10.26355/eurrev_202011_23620. Eur Rev Med Pharmacol Sci. 2020. PMID: 33215450 Free article.
In this review, we assess the effectiveness of liposomal bupivacaine against the traditional bupivacaine infiltration in the postoperative management of total hip arthroplasty (THA). ...Liposomal bupivacaine has selective benefits in terms of opioid consumpti …
In this review, we assess the effectiveness of liposomal bupivacaine against the traditional bupivacaine infiltration in the p …
Hyperbaric vs. isobaric bupivacaine for spinal anaesthesia for elective caesarean section: a Cochrane systematic review.
Sng BL, Han NLR, Leong WL, Sultana R, Siddiqui FJ, Assam PN, Chan ES, Tan KH, Sia AT. Sng BL, et al. Anaesthesia. 2018 Apr;73(4):499-511. doi: 10.1111/anae.14084. Epub 2017 Oct 17. Anaesthesia. 2018. PMID: 29044483 Free article.
Both isobaric and hyperbaric bupivacaine have been used for spinal anaesthesia for elective caesarean section, but it is not clear if one is better than the other. The primary objective of this systematic review was to determine the effectiveness and safety of hyperbaric …
Both isobaric and hyperbaric bupivacaine have been used for spinal anaesthesia for elective caesarean section, but it is not clear if …
SABER-Bupivacaine Reduces Postoperative Pain and Opioid Consumption After Arthroscopic Subacromial Decompression: A Randomized, Placebo-Controlled Trial.
Ekelund A, Peredistijs A, Grohs J, Meisner J, Verity N, Rasmussen S. Ekelund A, et al. J Am Acad Orthop Surg Glob Res Rev. 2022 May 1;6(5):e21.00287. doi: 10.5435/JAAOSGlobal-D-21-00287. J Am Acad Orthop Surg Glob Res Rev. 2022. PMID: 35584248 Free PMC article. Clinical Trial.
Sucrose acetate isobutyrate extended-release bupivacaine (SABER-Bupivacaine; trade name Posimir) is a novel depot formulation of bupivacaine designed to provide analgesia at the surgical site for up to 72 hours. ...The median time to first use of morphine res …
Sucrose acetate isobutyrate extended-release bupivacaine (SABER-Bupivacaine; trade name Posimir) is a novel depot formulation …
Efficacy of Liposomal Bupivacaine Versus Standard Bupivacaine Following Abdominal Surgeries: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Saad Sayed M, Rath S, Rasool W, Saeed F, Kashif H, Amer M. Saad Sayed M, et al. Pain Pract. 2025 Jun;25(5):e70048. doi: 10.1111/papr.70048. Pain Pract. 2025. PMID: 40387544 Review.
BACKGROUND: The development of liposomal bupivacaine (LB) as an anesthetic was widely lauded due to the potential benefits this drug claimed to carry. This systematic review and meta-analysis aimed to assess the efficacy of LB versus standard bupivacaine (SB) in imp …
BACKGROUND: The development of liposomal bupivacaine (LB) as an anesthetic was widely lauded due to the potential benefits this drug …
Use of hyperbaric versus isobaric bupivacaine for spinal anaesthesia for caesarean section.
Sia AT, Tan KH, Sng BL, Lim Y, Chan ES, Siddiqui FJ. Sia AT, et al. Cochrane Database Syst Rev. 2013 May 31;(5):CD005143. doi: 10.1002/14651858.CD005143.pub2. Cochrane Database Syst Rev. 2013. PMID: 23728652 Review.
Several trials have compared hyperbaric and isobaric bupivacaine but none have conclusively shown benefit of either. OBJECTIVES: This systematic review aimed to summarize the effectiveness and safety of hyperbaric versus isobaric bupivacaine in providing anaesthesia …
Several trials have compared hyperbaric and isobaric bupivacaine but none have conclusively shown benefit of either. OBJECTIVES: This …
Effect of scalp infiltration with bupivacaine on analgesic requirement following elective craniotomy.
Abdullahi AA, Aliyu A. Abdullahi AA, et al. Ann Afr Med. 2022 Oct-Dec;21(4):309-315. doi: 10.4103/aam.aam_89_20. Ann Afr Med. 2022. PMID: 36412328 Free PMC article. Clinical Trial.
Group A received 20 ml of 0.25% plain bupivacaine, while Group B received 20 ml normal saline. Pain scores were assessed using the Visual Analog Scale (VAS) on admission into the intensive care unit (ICU) then at 4, 8, 12, 16, 20, 24, and 48 h after surgery. ...There was a …
Group A received 20 ml of 0.25% plain bupivacaine, while Group B received 20 ml normal saline. Pain scores were assessed using the Vi …
Analgesic Characteristics of Bupivacaine Alone and in Combination with Dexmedetomidine or Meperidine in Spinal Anesthesia during Cesarean Section: A Double-Blind Randomized Clinical Trial Study.
Azemati S, Zarghami A, Jouybar R, Naderi-Boldaji V. Azemati S, et al. Pain Res Manag. 2022 Jul 18;2022:5111214. doi: 10.1155/2022/5111214. eCollection 2022. Pain Res Manag. 2022. PMID: 35899020 Free PMC article. Clinical Trial.
BACKGROUND: Comparing bupivacaine's adjuvants in spinal anesthesia, we assessed the specific blocking characteristics and adverse effects of bupivacaine alone and in combination with dexmedetomidine or meperidine in spinal anesthesia during cesarean section. …
BACKGROUND: Comparing bupivacaine's adjuvants in spinal anesthesia, we assessed the specific blocking characteristics and adve …
Efficacy of low-dose bupivacaine in spinal anaesthesia for Caesarean delivery: systematic review and meta-analysis.
Arzola C, Wieczorek PM. Arzola C, et al. Br J Anaesth. 2011 Sep;107(3):308-18. doi: 10.1093/bja/aer200. Epub 2011 Jul 14. Br J Anaesth. 2011. PMID: 21764820 Free article.
Different strategies have been attempted to prevent spinal-induced hypotension, including the use of low-dose bupivacaine. We conducted a systematic search for randomized controlled trials comparing the efficacy of spinal bupivacaine in low dose (LD 8 mg) with conve …
Different strategies have been attempted to prevent spinal-induced hypotension, including the use of low-dose bupivacaine. We conduct …
5,768 results