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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 2
1978 2
1979 3
1980 3
1981 8
1982 8
1983 10
1984 8
1985 6
1986 11
1987 17
1988 13
1989 7
1990 9
1991 7
1992 17
1993 22
1994 22
1995 12
1996 19
1997 21
1998 18
1999 12
2000 13
2001 14
2002 17
2003 22
2004 22
2005 34
2006 32
2007 34
2008 39
2009 28
2010 39
2011 52
2012 66
2013 78
2014 65
2015 68
2016 58
2017 55
2018 51
2019 49
2020 45
2021 55
2022 56
2023 62
2024 55
2025 61
2026 33

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1,291 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Buprenorphine-naloxone use in pregnancy: a systematic review and metaanalysis.
Link HM, Jones H, Miller L, Kaltenbach K, Seligman N. Link HM, et al. Am J Obstet Gynecol MFM. 2020 Aug;2(3):100179. doi: 10.1016/j.ajogmf.2020.100179. Epub 2020 Jul 3. Am J Obstet Gynecol MFM. 2020. PMID: 33345863
Of the 1875 mother-baby dyads available for analysis, medications prescribed as part of the medication-assisted treatment included buprenorphine-naloxone, buprenorphine alone, methadone, or long-acting opioids. There were no serious adverse maternal or neonatal outc …
Of the 1875 mother-baby dyads available for analysis, medications prescribed as part of the medication-assisted treatment included bupren …
Buprenorphine Compared with Methadone in Pregnancy: A Systematic Review and Meta-Analysis.
Kinsella M, Halliday LOE, Shaw M, Capel Y, Nelson SM, Kearns RJ. Kinsella M, et al. Subst Use Misuse. 2022;57(9):1400-1416. doi: 10.1080/10826084.2022.2083174. Epub 2022 Jun 25. Subst Use Misuse. 2022. PMID: 35758300 Free article.
Opioid substitution is recommended, but whether methadone or buprenorphine is the optimal agent remains unclear. METHODS: We searched EMBASE, PubMed, Web of Science, Scopus, Open Gray, CINAHL and the Cochrane Central Registry of Controlled Trials (CENTRAL) from inception t …
Opioid substitution is recommended, but whether methadone or buprenorphine is the optimal agent remains unclear. METHODS: We searched …
Emergency Department-Initiated Buprenorphine for Opioid Use Disorder: A Randomized Clinical Trial.
D'Onofrio G, Herring AA, Hawk KF, Perrone J, Cowan E, McCormack RP, Dziura J, Matthews AG, Pantalon MV, Owens P, Martel S, Coupet E Jr, Lofwall MR, Walsh SL, Edelman EJ, Carpenter JE, Strout TD, Baumann MR, Anderson E, Barrett TW, Dorey A, Taillac P, Cochran G, Crandall CS, Wilson J, Manteuffel J, Cole JB, Whiteside LK, Jones C, Samuels E, Huntley K, Fiellin DA; ED INNOVATION Investigators. D'Onofrio G, et al. JAMA. 2026 Mar 17;335(11):948-960. doi: 10.1001/jama.2025.27019. JAMA. 2026. PMID: 41670966 Free PMC article. Clinical Trial.
Engagement at 30 days was similar, with adjusted proportions of 43.8% with extended-release buprenorphine vs 44.9% with sublingual buprenorphine (adjusted difference, -1.5%; 95% CI, -6.2% to 3.2%). Precipitated withdrawal was rare: 6 (0.6%) with extended-release …
Engagement at 30 days was similar, with adjusted proportions of 43.8% with extended-release buprenorphine vs 44.9% with sublingual …
Buprenorphine for managing opioid withdrawal.
Gowing L, Ali R, White JM, Mbewe D. Gowing L, et al. Cochrane Database Syst Rev. 2017 Feb 21;2(2):CD002025. doi: 10.1002/14651858.CD002025.pub5. Cochrane Database Syst Rev. 2017. PMID: 28220474 Free PMC article.
The main comparators were clonidine or lofexidine (14 studies). Six studies compared buprenorphine versus methadone, and seven compared different rates of buprenorphine dose reduction. We assessed 12 studies as being at high risk of bias in at least one of seven dom …
The main comparators were clonidine or lofexidine (14 studies). Six studies compared buprenorphine versus methadone, and seven compar …
Weekly and Monthly Subcutaneous Buprenorphine Depot Formulations vs Daily Sublingual Buprenorphine With Naloxone for Treatment of Opioid Use Disorder: A Randomized Clinical Trial.
Lofwall MR, Walsh SL, Nunes EV, Bailey GL, Sigmon SC, Kampman KM, Frost M, Tiberg F, Linden M, Sheldon B, Oosman S, Peterson S, Chen M, Kim S. Lofwall MR, et al. JAMA Intern Med. 2018 Jun 1;178(6):764-773. doi: 10.1001/jamainternmed.2018.1052. JAMA Intern Med. 2018. PMID: 29799968 Free PMC article. Clinical Trial.
IMPORTANCE: Buprenorphine treatment for opioid use disorder may be improved by sustained-release formulations. OBJECTIVE: To determine whether treatment involving novel weekly and monthly subcutaneous (SC) buprenorphine depot formulations is noninferior to a daily s …
IMPORTANCE: Buprenorphine treatment for opioid use disorder may be improved by sustained-release formulations. OBJECTIVE: To determin …
Is Buprenorphine Effective for Chronic Pain? A Systematic Review and Meta-analysis.
Lazaridou A, Paschali M, Edwards RR, Gilligan C. Lazaridou A, et al. Pain Med. 2020 Dec 25;21(12):3691-3699. doi: 10.1093/pm/pnaa089. Pain Med. 2020. PMID: 32330264
OBJECTIVE: The objective was to perform a systematic review and meta-analysis of the literature on the effects of buprenorphine on chronic pain outcomes (i.e., patient-reported pain intensity) in patients with and without opioid use disorder (OUD). ...METHODS: Two separate …
OBJECTIVE: The objective was to perform a systematic review and meta-analysis of the literature on the effects of buprenorphine on ch …
Buprenorphine-naloxone versus buprenorphine for opioid use disorder during pregnancy: A systematic review and meta-analysis.
de Lima FR, Molino GOG, Gallo Ruelas M, Barbosa EC, Silva PHCMD, Guimarães FBM, Petrucci ABC, Silva GHSD, Sbardelotto ÂEE, Lança SB, Garbacka A. de Lima FR, et al. Drug Alcohol Depend. 2025 Jun 1;271:112632. doi: 10.1016/j.drugalcdep.2025.112632. Epub 2025 Feb 28. Drug Alcohol Depend. 2025. PMID: 40073807
This systematic review and meta-analysis aims to compare buprenorphine-naloxone vs buprenorphine alone for OUD during pregnancy, assessing gestational and neonatal outcomes. METHODS: We systematically searched MEDLINE, Embase, and Cochrane Library databases to ident …
This systematic review and meta-analysis aims to compare buprenorphine-naloxone vs buprenorphine alone for OUD during pregnanc …
The efficacy and safety of buprenorphine for the treatment of depression: A systematic review and meta-analysis.
Riblet NB, Young-Xu Y, Shiner B, Schnurr PP, Watts BV. Riblet NB, et al. J Psychiatr Res. 2023 May;161:393-401. doi: 10.1016/j.jpsychires.2023.03.037. Epub 2023 Mar 30. J Psychiatr Res. 2023. PMID: 37019069 Free PMC article.
METHODS: A meta-analysis comparing the efficacy, tolerability, and safety of buprenorphine (or combinations such as buprenorphine/samidorphan) versus control in improving symptoms in patients with depression. ...Most studies found buprenorphine was well-toler …
METHODS: A meta-analysis comparing the efficacy, tolerability, and safety of buprenorphine (or combinations such as buprenorphine …
Buprenorphine Versus Diclofenac for Pain Relief in Acute Pancreatitis: A Double-Blinded Randomized Controlled Trial.
Saini M, Samanta J, Kumar A, Choudhury A, Dhar J, Jafra A, Chauhan R, Muktesh G, Gupta P, Gupta V, Yadav TD, Kochhar R, Capurso G, De-Madaria E, Facciorusso A. Saini M, et al. Clin Gastroenterol Hepatol. 2024 Mar;22(3):532-541.e8. doi: 10.1016/j.cgh.2023.10.021. Epub 2023 Nov 3. Clin Gastroenterol Hepatol. 2024. PMID: 37924855 Clinical Trial.
RESULTS: Twenty-four patients were randomized to diclofenac and 24 to buprenorphine. The 2 groups were matched at baseline. The total amount of rescue fentanyl required was significantly lower in the buprenorphine group:130 mug, interquartile range (IQR), 80-255 vs …
RESULTS: Twenty-four patients were randomized to diclofenac and 24 to buprenorphine. The 2 groups were matched at baseline. The total …
Buprenorphine for treating cancer pain.
Schmidt-Hansen M, Bromham N, Taubert M, Arnold S, Hilgart JS. Schmidt-Hansen M, et al. Cochrane Database Syst Rev. 2015 Mar 31;2015(3):CD009596. doi: 10.1002/14651858.CD009596.pub4. Cochrane Database Syst Rev. 2015. PMID: 25826743 Free PMC article.
SELECTION CRITERIA: We included randomised controlled trials, with parallel-group or crossover design, comparing buprenorphine (any formulation and any route of administration) with placebo or an active drug (including buprenorphine) for cancer background pain in ad …
SELECTION CRITERIA: We included randomised controlled trials, with parallel-group or crossover design, comparing buprenorphine (any f …
1,291 results