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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
A randomized placebo controlled trial to evaluate the effects of butamirate and dextromethorphan on capsaicin induced cough in healthy volunteers.
Faruqi S, Wright C, Thompson R, Morice AH. Faruqi S, et al. Br J Clin Pharmacol. 2014 Dec;78(6):1272-80. doi: 10.1111/bcp.12458. Br J Clin Pharmacol. 2014. PMID: 24995954 Free PMC article. Clinical Trial.
Dextromethorphan was superior to placebo (P = 0.01) but butamirate failed to show significant activity with maximum attenuation at the 45 mg dose. ...The lack of efficacy of butamirate could be due to formulation issues at higher doses....
Dextromethorphan was superior to placebo (P = 0.01) but butamirate failed to show significant activity with maximum attenuation at th …
Comparative evaluation of the antitussive activity of butamirate citrate linctus versus clobutinol syrup.
Charpin J, Weibel MA. Charpin J, et al. Respiration. 1990;57(4):275-9. doi: 10.1159/000195855. Respiration. 1990. PMID: 2095610 Clinical Trial.
In a double-blind randomized study 60 patients with either irritative cough due to seasonal respiratory disorders or chronic cough of any etiology were treated with either butamirate citrate linctus (Sinecod, Zyma) or with clobutinol syrup (Silomat, Boehringer, Ingelheim) …
In a double-blind randomized study 60 patients with either irritative cough due to seasonal respiratory disorders or chronic cough of any et …
Relative bioavailability of different butamirate citrate preparations after single dose oral administration to 18 healthy volunteers.
Bohner H, Janiak PS, Nitsche V, Eichinger A, Schütz H. Bohner H, et al. Int J Clin Pharmacol Ther. 1997 Mar;35(3):117-22. Int J Clin Pharmacol Ther. 1997. PMID: 9089001 Clinical Trial.
Eighteen volunteers have been treated with different oral formulations of butamirate citrate according to 2 randomized 2-way crossover designs. In the first study (study I) the test preparation was a syrup (Demotussol Hustensirup, Demopharm), and the reference preparation …
Eighteen volunteers have been treated with different oral formulations of butamirate citrate according to 2 randomized 2-way crossove …
[Rengalin, a novel drug for treatment of cough in children. Intermediate data on multicentre, comparative randomized clinical trial].
Geppe NA, Kondyurina EG, Galustyan AN, Pak TE, Baltserovich NB, Zhiglinskaya OV, Kamaev AV, Lazareva SG, Laleko SL, Melnikova IM, Mikhalkova EV, Perminova OA, Sabitov AU, Spivakovsky YM. Geppe NA, et al. Antibiot Khimioter. 2014;59(7-8):16-24. Antibiot Khimioter. 2014. PMID: 25975103 Clinical Trial. Russian.
For 3 days the patients of group 1 (n = 71) and group 2 (n = 75) were treated with rengalin and sinekod (butamirate) respectively. For the following 4 days the patients (in case of viscid expectoration were treated with ambroxole in the age doses. ...CONCLUSION: He antitus …
For 3 days the patients of group 1 (n = 71) and group 2 (n = 75) were treated with rengalin and sinekod (butamirate) respectively. Fo …