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Year Number of Results
2010 1
2011 3
2012 1
2013 1
2014 2
2015 1
2016 4
2017 5
2018 2
2019 1
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2022 4
2023 7
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60 results

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Page 1
Enhancing KLF15 activity in cardiomyocytes: a novel approach to prevent pathological reprogramming and fibrosis via nuclease-deficient dCas9VPR.
Schoger E, Kim R, Bleckwedel F, Peralta TM, Priesmeier L, Fischer JA, Stengel L, Rocha C, Santos GL, Lutz S, Boileau E, Baumgarten N, Schulz MH, Dieterich C, Müller OJ, Cyganek L, Cabrera-Orefice A, Eberl H, Maack C, Streckfuss-Bömeke K, Pavez-Giani MG, Doroudgar S, Sossalla S, Zelarayán LC. Schoger E, et al. Among authors: cabrera orefice a. Signal Transduct Target Ther. 2026 Mar 3;11(1):76. doi: 10.1038/s41392-026-02593-9. Signal Transduct Target Ther. 2026. PMID: 41771837 Free PMC article.
The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells.
Herrle N, Malacarne PF, Warwick T, Cabrera-Orefice A, Chen Y, Gheisari M, Chatterjee S, Leisegang MS, Sarakpi T, Wionski S, Lopez M, Kader C, Teichmann T, Drekolia MK, Koch I, Keßler M, Klein S, Erhard Uschner F, Trebicka J, Brunst S, Proschak E, Günther S, Rosas-Lemus M, Baumgarten N, Klatt S, Speer T, Bibli SI, Segarra M, Acker-Palmer A, Wagner JUG, Wittig I, Dimmeler S, Schulz MH, Richards JB, Gilsbach R, T Denton T, Fleming I, Hannibal L, Brandes RP, Rezende F. Herrle N, et al. Among authors: cabrera orefice a. EMBO J. 2026 Feb;45(3):820-855. doi: 10.1038/s44318-025-00642-7. Epub 2025 Dec 17. EMBO J. 2026. PMID: 41408486 Free PMC article.
Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure.
Salazar-Ramírez FJ, Luévano-Martínez LA, Méndez-Fernández A, Bernal-Ramírez J, Morales-Ochoa CA, Silva-Platas C, Cabrera-Orefice A, Murrieta AC, Velasco-Bolom JL, Mendiola-Garza G, Contreras-Torres F, Torre-Amione G, Aiello EA, García-Rivas G. Salazar-Ramírez FJ, et al. Among authors: cabrera orefice a. Br J Pharmacol. 2026 Apr;183(7):1404-1426. doi: 10.1111/bph.70253. Epub 2025 Nov 14. Br J Pharmacol. 2026. PMID: 41239783
Pathogenesis of mtDNA point mutation m.10191T>C affecting complex I function is a multifactorial process leading to metabolic remodeling of mitochondria.
Ahmadi ZA, Cabrera-Orefice A, Zaninello M, Barth E, Veronese M, Rodenburg R, Rugarli EI, Brodesser S, Arnold S, Brandt U. Ahmadi ZA, et al. Among authors: cabrera orefice a. Biochim Biophys Acta Mol Basis Dis. 2026 Feb;1872(2):168070. doi: 10.1016/j.bbadis.2025.168070. Epub 2025 Oct 10. Biochim Biophys Acta Mol Basis Dis. 2026. PMID: 41077097 Free article.
RTN4IP1 is required for the final stages of mitochondrial complex I assembly and CoQ biosynthesis.
Oláhová M, Guerra RM, Collier JJ, Heidler J, Thompson K, White CR, Castañeda-Tamez P, Cabrera-Orefice A, Lightowlers RN, Chrzanowska-Lightowlers ZMA, Galkin A, Wittig I, Pagliarini DJ, Taylor RW. Oláhová M, et al. Among authors: cabrera orefice a. EMBO J. 2025 Oct;44(19):5482-5508. doi: 10.1038/s44318-025-00533-x. Epub 2025 Aug 26. EMBO J. 2025. PMID: 40859035 Free PMC article.
Venomics of the Arabian saw-scaled viper (Echis coloratus) through transcriptome-guided proteomics and in vitro functional profiling.
Avella I, Schulte L, Damm M, Uhrig L, Cabrera-Orefice A, Eichberg J, Hardes K, Hurka S, Lindner T, Vilcinskas A, Lüddecke T. Avella I, et al. Among authors: cabrera orefice a. PLoS Negl Trop Dis. 2025 Aug 14;19(8):e0013439. doi: 10.1371/journal.pntd.0013439. eCollection 2025 Aug. PLoS Negl Trop Dis. 2025. PMID: 40811711 Free PMC article.
Complexome profiling showed impaired immunoproteasome assembly in a novel PRAAS subtype caused by monoallelic PSMB8 variants.
Wijngaard R, van der Made CI, Kalkan Uçar S, Ramakrishnan G, Rosenfeld JA, Vogel TP, Nicholas SK, Weisz-Hubshman M; Undiagnosed Diseases Network; Cabrera-Orefice A, Siebels B, Mair T, Schlüter H, Smeets RL, van Beek R, van Karnebeek CDM, Hoischen A, Vissers LELM, Wortmann SB, Wevers RA, Oud MM, Guerrero-Castillo S. Wijngaard R, et al. Among authors: cabrera orefice a. medRxiv [Preprint]. 2025 Jun 26:2025.06.25.25330124. doi: 10.1101/2025.06.25.25330124. medRxiv. 2025. PMID: 40666351 Free PMC article. Preprint.
Microprotein SMIM26 drives oxidative metabolism via serine-responsive mitochondrial translation.
Nah J, Mahendran S, Kerouanton B, Cui L, Hock DH, Cabrera-Orefice A, Dunlap K, Robinson D, Tung DWH, Leong SH, Tan KY, Chothani SP, Sun J, Dziegowska A, Leszczynska G, Rackham OJL, Wittig I, Dedon P, Ducker GS, Stroud DA, Ho L. Nah J, et al. Among authors: cabrera orefice a. Mol Cell. 2025 Jul 17;85(14):2759-2775.e12. doi: 10.1016/j.molcel.2025.05.033. Epub 2025 Jun 26. Mol Cell. 2025. PMID: 40578345
60 results