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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1891 1
1935 2
1936 1
1944 1
1945 1
1947 7
1948 2
1949 4
1950 3
1951 3
1952 4
1953 6
1954 2
1955 3
1957 1
1958 4
1959 2
1960 3
1961 2
1963 8
1964 5
1965 4
1966 3
1967 1
1968 2
1969 1
1970 2
1971 2
1972 1
1973 4
1974 1
1975 4
1976 2
1977 3
1978 1
1979 1
1980 2
1981 3
1982 3
1983 2
1984 8
1985 2
1986 2
1987 1
1988 2
1989 3
1990 6
1991 11
1992 3
1993 6
1994 9
1995 5
1996 8
1997 8
1998 9
1999 12
2000 18
2001 15
2002 20
2003 26
2004 24
2005 34
2006 21
2007 36
2008 44
2009 47
2010 35
2011 52
2012 47
2013 57
2014 74
2015 86
2016 89
2017 96
2018 110
2019 108
2020 106
2021 130
2022 143
2023 56

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1,509 results

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Page 1
Impact of Coffee and Cacao Purine Metabolites on Neuroplasticity and Neurodegenerative Disease.
Camandola S, Plick N, Mattson MP. Camandola S, et al. Neurochem Res. 2019 Jan;44(1):214-227. doi: 10.1007/s11064-018-2492-0. Epub 2018 Feb 8. Neurochem Res. 2019. PMID: 29417473 Free PMC article. Review.
Increasing evidence suggests that regular consumption of coffee, tea and dark chocolate (cacao) can promote brain health and may reduce the risk of age-related neurodegenerative disorders. ...Downstream xanthine metabolites, such as theobromine and theophylline, may also c …
Increasing evidence suggests that regular consumption of coffee, tea and dark chocolate (cacao) can promote brain health and may redu …
Cacao biotechnology: current status and future prospects.
Wickramasuriya AM, Dunwell JM. Wickramasuriya AM, et al. Plant Biotechnol J. 2018 Jan;16(1):4-17. doi: 10.1111/pbi.12848. Epub 2017 Nov 19. Plant Biotechnol J. 2018. PMID: 28985014 Free PMC article. Review.
Theobroma cacao-The Food of the Gods, provides the raw material for the multibillion dollar chocolate industry and is also the main source of income for about 6 million smallholders around the world. ...In addition, in order to obtain an insight into the latest innovations …
Theobroma cacao-The Food of the Gods, provides the raw material for the multibillion dollar chocolate industry and is also the main s …
Chocolate.
[No authors listed] [No authors listed] 2022 Sep 19. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2022 Sep 19. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30372004 Free Books & Documents. Review.
Low intake of chocolate by a nursing mother is not problematic, but extreme amounts can affect the infant. Cacao butter, which is derived from Theobroma cacao, was found to be superior to mother's milk when applied to the nipples during the first 10 days postpartum. …
Low intake of chocolate by a nursing mother is not problematic, but extreme amounts can affect the infant. Cacao butter, which is der …
Health benefits of methylxanthines in cacao and chocolate.
Franco R, Oñatibia-Astibia A, Martínez-Pinilla E. Franco R, et al. Nutrients. 2013 Oct 18;5(10):4159-73. doi: 10.3390/nu5104159. Nutrients. 2013. PMID: 24145871 Free PMC article. Review.
Caffeine and theobromine are the most abundant methylxanthines in cacao and their physiological effects are notable. Their health-promoting benefits are so remarkable that chocolate is explored as a functional food. The consequences of adenosine receptor blockade by natura …
Caffeine and theobromine are the most abundant methylxanthines in cacao and their physiological effects are notable. Their health-pro …
Polyphenols: Inflammation.
Natsume M. Natsume M. Curr Pharm Des. 2018;24(2):191-202. doi: 10.2174/1381612823666171109104141. Curr Pharm Des. 2018. PMID: 29119920 Review.
BACKGROUND: Polyphenols widely distributed in plants, fruits and vegetables have received considerable attention on account of their physiological functions, including their antioxidant and anti-inflammatory properties. Some antioxidant components of cacao liquor prepared …
BACKGROUND: Polyphenols widely distributed in plants, fruits and vegetables have received considerable attention on account of their physiol …
Effect of cacao polyphenol-rich chocolate on postprandial glycemia, insulin, and incretin secretion in healthy participants.
Kawakami Y, Watanabe Y, Mazuka M, Yagi N, Sawazaki A, Koganei M, Natsume M, Kuriki K, Morimoto T, Asai T, Arai H. Kawakami Y, et al. Nutrition. 2021 May;85:111128. doi: 10.1016/j.nut.2020.111128. Epub 2021 Jan 2. Nutrition. 2021. PMID: 33545542 Free article. Clinical Trial.
OBJECTIVES: There is substantial interest in using dark chocolate to prevent postprandial hyperglycemia. We investigated the effects of cacao polyphenol-rich chocolate on postprandial glycemic and insulinemic responses and whether cacao polyphenol-rich chocolate inc …
OBJECTIVES: There is substantial interest in using dark chocolate to prevent postprandial hyperglycemia. We investigated the effects of c …
The History of Cacao and Its Diseases in the Americas.
Díaz-Valderrama JR, Leiva-Espinoza ST, Aime MC. Díaz-Valderrama JR, et al. Phytopathology. 2020 Oct;110(10):1604-1619. doi: 10.1094/PHYTO-05-20-0178-RVW. Epub 2020 Sep 14. Phytopathology. 2020. PMID: 32820671 Review.
Cacao is a commodity crop from the tropics cultivated by about 6 million smallholder farmers. The tree, Theobroma cacao, originated in the Upper Amazon where it was domesticated ca. 5450 to 5300 B.P. ...
Cacao is a commodity crop from the tropics cultivated by about 6 million smallholder farmers. The tree, Theobroma cacao, origi …
Cacao Swollen Shoot Viruses in Ghana.
Gyamera EA, Domfeh O, Ameyaw GA. Gyamera EA, et al. Plant Dis. 2023 May;107(5):1261-1278. doi: 10.1094/PDIS-10-22-2412-FE. Epub 2023 May 19. Plant Dis. 2023. PMID: 36510419 Free article. Review.
Cacao swollen shoot virus causes cacao swollen shoot disease of Theobroma cacao (cacao) plants. At least six cacao-infecting Badnavirus species-Cacao swollen shoot Togo A virus, Cacao swollen shoot Togo B virus (previously known as …
Cacao swollen shoot virus causes cacao swollen shoot disease of Theobroma cacao (cacao) plants. At least six …
Theobroma cacao: Somatic Embryogenesis.
Guillou C, Verdier D. Guillou C, et al. Methods Mol Biol. 2022;2527:69-81. doi: 10.1007/978-1-0716-2485-2_6. Methods Mol Biol. 2022. PMID: 35951184
A two-step process combining direct and indirect somatic embryogenesis, on solid and liquid medium, respectively is described for Theobroma cacao L. Staminodes and petals from unopened bud flowers are used to induce primary direct embryos. ...Despite a very strong clone de …
A two-step process combining direct and indirect somatic embryogenesis, on solid and liquid medium, respectively is described for Theobroma …
Chocolate Under Threat from Old and New Cacao Diseases.
Marelli JP, Guest DI, Bailey BA, Evans HC, Brown JK, Junaid M, Barreto RW, Lisboa DO, Puig AS. Marelli JP, et al. Phytopathology. 2019 Aug;109(8):1331-1343. doi: 10.1094/PHYTO-12-18-0477-RVW. Epub 2019 Jul 1. Phytopathology. 2019. PMID: 31115251 Free article. Review.
Theobroma cacao, the source of chocolate, is affected by destructive diseases wherever it is grown. ...Cacao swollen shoot disease caused by Cacao swollen shoot virus is rapidly spreading in West Africa. ...
Theobroma cacao, the source of chocolate, is affected by destructive diseases wherever it is grown. ...Cacao swollen shoot dis …
1,509 results