Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1982 1
1986 1
1987 1
1994 1
1995 1
1996 4
1997 5
1998 1
1999 3
2001 2
2002 3
2003 3
2004 2
2005 2
2006 1
2007 3
2008 3
2009 1
2010 2
2012 2
2013 2
2014 1
2016 1
2017 1
2018 1
2019 2
2020 2
2021 1
2025 1
2026 1

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

50 results

Results by year

Filters applied: . Clear all
Page 1
Separate effects of the coffee diterpenes cafestol and kahweol on serum lipids and liver aminotransferases.
Urgert R, Essed N, van der Weg G, Kosmeijer-Schuil TG, Katan MB. Urgert R, et al. Am J Clin Nutr. 1997 Feb;65(2):519-24. doi: 10.1093/ajcn/65.2.519. Am J Clin Nutr. 1997. PMID: 9022539 Clinical Trial.
The activity of kahweol is unknown. In a randomized, double-blind crossover study, we gave 10 healthy male volunteers either pure cafestol (61-64 mg/d) or a mixture of cafestol (60 mg/d) and kahweol (48-54 mg/d) for 28 d. ...Both cafestol and …
The activity of kahweol is unknown. In a randomized, double-blind crossover study, we gave 10 healthy male volunteers either pure …
Hepatoprotective and antioxidant effects of the coffee diterpenes kahweol and cafestol on carbon tetrachloride-induced liver damage in mice.
Lee KJ, Choi JH, Jeong HG. Lee KJ, et al. Food Chem Toxicol. 2007 Nov;45(11):2118-25. doi: 10.1016/j.fct.2007.05.010. Epub 2007 May 24. Food Chem Toxicol. 2007. PMID: 17590492
The histopathological evaluation of the livers also revealed that kahweol and cafestol reduced the incidence of liver lesions induced by CCl(4). ...Kahweol and cafestol exhibited antioxidant effects on FeCl(2)-ascorbate induced lipid pero …
The histopathological evaluation of the livers also revealed that kahweol and cafestol reduced the incidence of live …
Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice.
Lam LK, Sparnins VL, Wattenberg LW. Lam LK, et al. J Med Chem. 1987 Aug;30(8):1399-403. doi: 10.1021/jm00391a022. J Med Chem. 1987. PMID: 3612687
The coffee constituents cafestol and kahweol are inducers of the activity of the detoxifying enzyme, glutathione S-transferase in laboratory animals. ...In contrast, these compounds still retained their ability to induce increased levels of acid-soluble sulfhydryls …
The coffee constituents cafestol and kahweol are inducers of the activity of the detoxifying enzyme, glutathione S-transferase …
Coffee and liver health.
Morisco F, Lembo V, Mazzone G, Camera S, Caporaso N. Morisco F, et al. J Clin Gastroenterol. 2014 Nov-Dec;48 Suppl 1:S87-90. doi: 10.1097/MCG.0000000000000240. J Clin Gastroenterol. 2014. PMID: 25291138 Review.
Over the past 20 years, an increasing number of epidemiological and experimental studies have demonstrated the positive effects of coffee on chronic liver diseases. Coffee consumption has been inversely associated with the activity of liver enzymes in subjects at ri …
Over the past 20 years, an increasing number of epidemiological and experimental studies have demonstrated the positive effects of coffee on …
Effects of cafestol and kahweol from coffee grounds on serum lipids and serum liver enzymes in humans.
Urgert R, Schulz AG, Katan MB. Urgert R, et al. Am J Clin Nutr. 1995 Jan;61(1):149-54. doi: 10.1093/ajcn/61.1.149. Am J Clin Nutr. 1995. PMID: 7825527 Free article. Clinical Trial.
The diterpenes cafestol and kahweol are present in unfiltered coffee in oil droplets and floating fines. ...
The diterpenes cafestol and kahweol are present in unfiltered coffee in oil droplets and floating fines. ...
Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity.
Cavin C, Holzhaeuser D, Scharf G, Constable A, Huber WW, Schilter B. Cavin C, et al. Food Chem Toxicol. 2002 Aug;40(8):1155-63. doi: 10.1016/s0278-6915(02)00029-7. Food Chem Toxicol. 2002. PMID: 12067578 Review.
In animal models and cell culture systems, the coffee diterpenes cafestol and kahweol (C+K) were shown to produce a broad range of biochemical effects resulting in a reduction of the genotoxicity of several carcinogens including 7,12-dimethylbenz[a]anthracene (DMBA) …
In animal models and cell culture systems, the coffee diterpenes cafestol and kahweol (C+K) were shown to produce a broad rang …
[Coffee as hepatoprotective factor].
Szántová M, Ďurkovičová Z. Szántová M, et al. Vnitr Lek. 2016 Winter;62(12):990-997. Vnitr Lek. 2016. PMID: 28139128 Review. Czech.
Consensual protective effect of coffee on the progression of chronic liver diseases (NASH, viral hepatitis, liver cirrhosis, hepatocelullar carcinoma) was detected in experimental, clinical and large population studies together with decrease of mortality. ...Inverse …
Consensual protective effect of coffee on the progression of chronic liver diseases (NASH, viral hepatitis, liver cirrhosis, h …
Isolation and identification of kahweol palmitate and cafestol palmitate as active constituents of green coffee beans that enhance glutathione S-transferase activity in the mouse.
Lam LK, Sparnins VL, Wattenberg LW. Lam LK, et al. Cancer Res. 1982 Apr;42(4):1193-8. Cancer Res. 1982. PMID: 7059995
A similar diterpene ester, cafestol palmitate, isolated from green coffee beans was active but less so than was kahweol palmitate. ...Kahweol palmitate and cafestol palmitate were extracted from green coffee beans into petroleum ether. ...
A similar diterpene ester, cafestol palmitate, isolated from green coffee beans was active but less so than was kahweol palmit …
[Coffee in Cancer Chemoprevention].
Neuwirthová J, Gál B, Smilek P, Urbánková P. Neuwirthová J, et al. Klin Onkol. 2017 Spring;30(2):106-114. doi: 10.14735/amko2017106. Klin Onkol. 2017. PMID: 28397506 Review. Czech.
Several modes of action have been proposed, namely, inhibition of oxidative stress and damage, activation of metabolizing liver enzymes involved in carcinogen detoxification processes, and anti-inflammatory effects. ...Coffee also contains two specific diterpenes, cafes …
Several modes of action have been proposed, namely, inhibition of oxidative stress and damage, activation of metabolizing liver enzym …
Coffee and its chemopreventive components Kahweol and Cafestol increase the activity of O6-methylguanine-DNA methyltransferase in rat liver--comparison with phase II xenobiotic metabolism.
Huber WW, Scharf G, Nagel G, Prustomersky S, Schulte-Hermann R, Kaina B. Huber WW, et al. Mutat Res. 2003 Jan 28;522(1-2):57-68. doi: 10.1016/s0027-5107(02)00264-6. Mutat Res. 2003. PMID: 12517412
A lower rate of colon cancer was observed in consumers of coffee with a high content of the diterpenes Kahweol and Cafestol (K/C). In animal models, K/C have been found to protect against the mutagenic/carcinogenic effects of compounds such as 2-amino-1-methyl-6-phe …
A lower rate of colon cancer was observed in consumers of coffee with a high content of the diterpenes Kahweol and Cafestol (K …
50 results