Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 2
1967 1
1970 2
1973 1
1974 3
1975 1
1976 2
1977 2
1978 5
1979 3
1980 5
1981 4
1982 7
1983 6
1984 6
1985 13
1986 11
1987 17
1988 12
1989 20
1990 28
1991 35
1992 26
1993 24
1994 38
1995 38
1996 38
1997 30
1998 38
1999 32
2000 34
2001 54
2002 44
2003 46
2004 50
2005 70
2006 72
2007 70
2008 60
2009 63
2010 69
2011 81
2012 89
2013 89
2014 117
2015 128
2016 144
2017 113
2018 101
2019 110
2020 121
2021 153
2022 138
2023 105
2024 150
2025 131
2026 59

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

2,540 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Effects of caffeine on anxiety and panic attacks in patients with panic disorder: A systematic review and meta-analysis.
Klevebrant L, Frick A. Klevebrant L, et al. Gen Hosp Psychiatry. 2022 Jan-Feb;74:22-31. doi: 10.1016/j.genhosppsych.2021.11.005. Epub 2021 Dec 2. Gen Hosp Psychiatry. 2022. PMID: 34871964 Free article.
Caffeine also increases anxiety in PD patients as well as among healthy adults at these doses although the exact relationship between caffeine-induced anxiety and panic attacks remains uncertain. The results suggest that caffeine targets important mechanisms
Caffeine also increases anxiety in PD patients as well as among healthy adults at these doses although the exact relationship between
Caffeine Intake Alters Recovery Sleep after Sleep Deprivation.
Pauchon B, Beauchamps V, Gomez-Mérino D, Erblang M, Drogou C, Beers PV, Guillard M, Quiquempoix M, Léger D, Chennaoui M, Sauvet F. Pauchon B, et al. Nutrients. 2024 Oct 11;16(20):3442. doi: 10.3390/nu16203442. Nutrients. 2024. PMID: 39458438 Free PMC article. Clinical Trial.
Nevertheless, caffeine can alter sleep duration and quality, particularly during recovery sleep. We evaluated the effects of acute caffeine intake on the duration and quality of recovery sleep following total sleep deprivation (TSD), taking into account daily caf
Nevertheless, caffeine can alter sleep duration and quality, particularly during recovery sleep. We evaluated the effects of acute …
Maternal caffeine consumption during pregnancy and offspring cord blood DNA methylation: an epigenome-wide association study meta-analysis.
Schellhas L, Monasso GS, Felix JF, Jaddoe VW, Huang P, Fernández-Barrés S, Vrijheid M, Pesce G, Annesi-Maesano I, Page CM, Brantsæter AL, Bekkhus M, Håberg SE, London SJ, Munafò MR, Zuccolo L, Sharp GC. Schellhas L, et al. Epigenomics. 2023 Nov;15(22):1179-1193. doi: 10.2217/epi-2023-0263. Epub 2023 Nov 29. Epigenomics. 2023. PMID: 38018434 Free PMC article. Review.
Differential methylation related to self-reported caffeine intake (mg/day) from coffee, tea and cola was compared with assess whether caffeine is driving effects. Results: One CpG site (cg19370043, PRRX1) was associated with caffeine and another (cg14591243, …
Differential methylation related to self-reported caffeine intake (mg/day) from coffee, tea and cola was compared with assess whether …
Caffeine, but not paracetamol (acetaminophen), enhances muscular endurance, strength, and power.
Scapec B, Grgic J, Varovic D, Mikulic P. Scapec B, et al. J Int Soc Sports Nutr. 2024 Dec;21(1):2400513. doi: 10.1080/15502783.2024.2400513. Epub 2024 Sep 8. J Int Soc Sports Nutr. 2024. PMID: 39246027 Free PMC article. Clinical Trial.
BACKGROUND: Caffeine is one of the most popular ergogenic aids consumed by athletes. Caffeine's ergogenic effect has been generally explained by its ability to bind to adenosine receptors, thus modulating pain and reducing perceived exertion. ...This study ai …
BACKGROUND: Caffeine is one of the most popular ergogenic aids consumed by athletes. Caffeine's ergogenic effect has be …
Regular Caffeine Intake Delays REM Sleep Promotion and Attenuates Sleep Quality in Healthy Men.
Weibel J, Lin YS, Landolt HP, Berthomier C, Brandewinder M, Kistler J, Rehm S, Rentsch KM, Meyer M, Borgwardt S, Cajochen C, Reichert CF. Weibel J, et al. J Biol Rhythms. 2021 Aug;36(4):384-394. doi: 10.1177/07487304211013995. Epub 2021 May 23. J Biol Rhythms. 2021. PMID: 34024173 Free PMC article. Clinical Trial.
However, it is not known whether such changes persist under chronic caffeine consumption during daytime. Twenty male caffeine consumers (26.4 4 years old, habitual caffeine intake 478.1 102.8 mg/day) participated in a double-blind crossover study. Each vo …
However, it is not known whether such changes persist under chronic caffeine consumption during daytime. Twenty male caffeine
Association between caffeine intake and erectile dysfunction: a meta-analysis of cohort studies.
Karimi M, Asbaghi O, Kazemi K, Sedgi FM, Soleimani E, Moghadam HK. Karimi M, et al. J Health Popul Nutr. 2024 Sep 28;43(1):154. doi: 10.1186/s41043-024-00645-w. J Health Popul Nutr. 2024. PMID: 39342393 Free PMC article.
This meta-analysis aims to evaluate the association between caffeine intake and the risk of ED by analyzing data from cohort studies. METHODS: A systematic search was conducted across PubMed, Web of Science, Scopus, and Embase databases, and a manual search was conducted o …
This meta-analysis aims to evaluate the association between caffeine intake and the risk of ED by analyzing data from cohort studies. …
The impact of daily caffeine intake on nighttime sleep in young adult men.
Weibel J, Lin YS, Landolt HP, Kistler J, Rehm S, Rentsch KM, Slawik H, Borgwardt S, Cajochen C, Reichert CF. Weibel J, et al. Sci Rep. 2021 Feb 25;11(1):4668. doi: 10.1038/s41598-021-84088-x. Sci Rep. 2021. PMID: 33633278 Free PMC article. Clinical Trial.
To address this question, we investigated the sleep of twenty male young habitual caffeine consumers during a double-blind, randomized, crossover study including three 10-day conditions: caffeine (3 150 mg caffeine daily), withdrawal (3 150 mg caffeine
To address this question, we investigated the sleep of twenty male young habitual caffeine consumers during a double-blind, randomize …
Effects of caffeine on the human circadian clock in vivo and in vitro.
Burke TM, Markwald RR, McHill AW, Chinoy ED, Snider JA, Bessman SC, Jung CM, O'Neill JS, Wright KP Jr. Burke TM, et al. Sci Transl Med. 2015 Sep 16;7(305):305ra146. doi: 10.1126/scitranslmed.aac5125. Sci Transl Med. 2015. PMID: 26378246 Free PMC article. Clinical Trial.
Caffeine's wakefulness-promoting and sleep-disrupting effects are well established, yet whether caffeine affects human circadian timing is unknown. ...Furthermore, using human osteosarcoma U2OS cells expressing clock gene luciferase reporters, we found a dose
Caffeine's wakefulness-promoting and sleep-disrupting effects are well established, yet whether caffeine affects human
The Effects of Caffeine on Jumping Performance and Maximal Strength in Female Collegiate Athletes.
Burke BI, Travis SK, Gentles JA, Sato K, Lang HM, Bazyler CD. Burke BI, et al. Nutrients. 2021 Jul 22;13(8):2496. doi: 10.3390/nu13082496. Nutrients. 2021. PMID: 34444656 Free PMC article. Clinical Trial.
Caffeine is often used in a variety of forms to enhance athletic performance; however, research regarding caffeine's effects on strength and power in female athletes is lacking. ...Resting systolic blood pressure was significantly greater following caffein
Caffeine is often used in a variety of forms to enhance athletic performance; however, research regarding caffeine's ef
Caffeine for asthma.
Welsh EJ, Bara A, Barley E, Cates CJ. Welsh EJ, et al. Cochrane Database Syst Rev. 2010 Jan 20;2010(1):CD001112. doi: 10.1002/14651858.CD001112.pub2. Cochrane Database Syst Rev. 2010. PMID: 20091514 Free PMC article.
OBJECTIVES: To assess the effects of caffeine on lung function and identify whether there is a need to control for caffeine consumption prior to either lung function or exhaled nitric oxide testing. ...People may need to avoid caffeine for at least four hours …
OBJECTIVES: To assess the effects of caffeine on lung function and identify whether there is a need to control for caffeine co …
2,540 results