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210 results

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Page 1
The epidemiology of Parkinson's disease: risk factors and prevention.
Ascherio A, Schwarzschild MA. Ascherio A, et al. Lancet Neurol. 2016 Nov;15(12):1257-1272. doi: 10.1016/S1474-4422(16)30230-7. Epub 2016 Oct 11. Lancet Neurol. 2016. PMID: 27751556 Review.
Randomised trials are investigating the possibility that some of the negative risk factors might be neuroprotective and thus beneficial in individuals with early Parkinson's disease, particularly with respect to smoking (nicotine), caffeine, and …
Randomised trials are investigating the possibility that some of the negative risk factors might be neuroprotective and thus benefici …
The neuroprotective effects of caffeine in neurodegenerative diseases.
Kolahdouzan M, Hamadeh MJ. Kolahdouzan M, et al. CNS Neurosci Ther. 2017 Apr;23(4):272-290. doi: 10.1111/cns.12684. CNS Neurosci Ther. 2017. PMID: 28317317 Free PMC article. Review.
In Alzheimer's disease (AD), caffeine is beneficial in both men and women, in humans and animals. Similar effects of caffeine were observed in men with Parkinson's disease (PD); however, the effect of caffeine in female PD patients …
In Alzheimer's disease (AD), caffeine is beneficial in both men and women, in humans and animals. Similar effects of caffei …
Neuroprotective Effect of Caffeine in Alzheimer's Disease.
M Yelanchezian YM, Waldvogel HJ, Faull RLM, Kwakowsky A. M Yelanchezian YM, et al. Molecules. 2022 Jun 10;27(12):3737. doi: 10.3390/molecules27123737. Molecules. 2022. PMID: 35744865 Free PMC article. Review.
There is suggestive evidence from clinical studies that caffeine is neuroprotective against dementia and possibly AD (20 out of 30 studies support this), but further studies, such as the "ideal" study proposed in this review, are required to prove this link. Clinica …
There is suggestive evidence from clinical studies that caffeine is neuroprotective against dementia and possibly AD (20 out o …
Neuroprotective Effects of Coffee Bioactive Compounds: A Review.
Socała K, Szopa A, Serefko A, Poleszak E, Wlaź P. Socała K, et al. Int J Mol Sci. 2020 Dec 24;22(1):107. doi: 10.3390/ijms22010107. Int J Mol Sci. 2020. PMID: 33374338 Free PMC article. Review.
Regular coffee intake may protect from many chronic disorders, including cardiovascular disease, type 2 diabetes, obesity, and some types of cancer. Importantly, coffee consumption seems to be also correlated with a decreased risk of developing some neurodegenera …
Regular coffee intake may protect from many chronic disorders, including cardiovascular disease, type 2 diabetes, obesity, and …
Coffee and Parkinson's disease.
Asuku AO, Ayinla MT, Olajide TS, Oyerinde TO, Yusuf JA, Bayo-Olugbami AA, Fajemidagba GA. Asuku AO, et al. Prog Brain Res. 2024;289:1-19. doi: 10.1016/bs.pbr.2024.06.001. Epub 2024 Jul 2. Prog Brain Res. 2024. PMID: 39168575 Review.
Parkinson's disease (PD) is a prevalent neurodegenerative disease marked by dopaminergic neuronal loss and misfolded alpha-synuclein (alpha-syn) accumulation, which results in both motor and cognitive symptoms. ...Epidemiological studies imply a …
Parkinson's disease (PD) is a prevalent neurodegenerative disease marked by dopaminergic neuronal loss an …
Association of Coffee Consumption and Prediagnostic Caffeine Metabolites With Incident Parkinson Disease in a Population-Based Cohort.
Zhao Y, Lai Y, Konijnenberg H, Huerta JM, Vinagre-Aragon A, Sabin JA, Hansen J, Petrova D, Sacerdote C, Zamora-Ros R, Pala V, Heath AK, Panico S, Guevara M, Masala G, Lill CM, Miller GW, Peters S, Vermeulen R. Zhao Y, et al. Neurology. 2024 Apr 23;102(8):e209201. doi: 10.1212/WNL.0000000000209201. Epub 2024 Mar 21. Neurology. 2024. PMID: 38513162 Free PMC article.
BACKGROUND AND OBJECTIVES: Inverse associations between caffeine intake and Parkinson disease (PD) have been frequently implicated in human studies. ...DISCUSSION: This study demonstrates that the neuroprotection of coffee on PD is attributed to caf …
BACKGROUND AND OBJECTIVES: Inverse associations between caffeine intake and Parkinson disease (PD) have been frequently …
Caffeine and Parkinson's Disease: Multiple Benefits and Emerging Mechanisms.
Ren X, Chen JF. Ren X, et al. Front Neurosci. 2020 Dec 17;14:602697. doi: 10.3389/fnins.2020.602697. eCollection 2020. Front Neurosci. 2020. PMID: 33390888 Free PMC article. Review.
Parkinson's disease (PD) is the second most common neurodegenerative disorder, characterized by dopaminergic neurodegeneration, motor impairment and non-motor symptoms. ...While caffeine has complex pharmacological profiles, studies with genetic …
Parkinson's disease (PD) is the second most common neurodegenerative disorder, characterized by dopaminergic neu …
A Review of the Role of Green Tea (Camellia sinensis) in Antiphotoaging, Stress Resistance, Neuroprotection, and Autophagy.
Prasanth MI, Sivamaruthi BS, Chaiyasut C, Tencomnao T. Prasanth MI, et al. Nutrients. 2019 Feb 23;11(2):474. doi: 10.3390/nu11020474. Nutrients. 2019. PMID: 30813433 Free PMC article. Review.
Growing evidence suggests that green tea can also be used as a potential agent to mediate neurodegenerative diseases, including Alzheimer's disease. EGCG, an abundant catechin in tea, was found to suppress the neurotoxicity induced by Abeta as it activates gl …
Growing evidence suggests that green tea can also be used as a potential agent to mediate neurodegenerative diseases, includin …
Methylxanthines and Neurodegenerative Diseases: An Update.
Janitschke D, Lauer AA, Bachmann CM, Grimm HS, Hartmann T, Grimm MOW. Janitschke D, et al. Nutrients. 2021 Feb 28;13(3):803. doi: 10.3390/nu13030803. Nutrients. 2021. PMID: 33671099 Free PMC article. Review.
Especially in the past years, the impact of methylxanthines in neurodegenerative diseases has been extensively studied and several new aspects have been elucidated. In this review we summarize the findings of methylxanthines linked to Alzheimers disease, P …
Especially in the past years, the impact of methylxanthines in neurodegenerative diseases has been extensively studied and sev …
Coffee and Alzheimer's disease.
Mirzaei F, Agbaria L, Bhatnagar K, Sirimanne N, Omar A'amar N, Jindal V, Gerald Thilagendra A, Tawfiq Raba F. Mirzaei F, et al. Prog Brain Res. 2024;289:21-55. doi: 10.1016/bs.pbr.2024.06.002. Epub 2024 Jul 3. Prog Brain Res. 2024. PMID: 39168581 Review.
Coffee, a universally consumed beverage, is known to contain thousands of bioactive constituents that have garnered interest due to their potential neuroprotective effects against various neurodegenerative disorders, including Alzheimer's disease (AD). …
Coffee, a universally consumed beverage, is known to contain thousands of bioactive constituents that have garnered interest due to their po …
Caffeine, creatine, GRIN2A and Parkinson's disease progression.
Simon DK, Wu C, Tilley BC, Lohmann K, Klein C, Payami H, Wills AM, Aminoff MJ, Bainbridge J, Dewey R, Hauser RA, Schaake S, Schneider JS, Sharma S, Singer C, Tanner CM, Truong D, Wei P, Wong PS, Yang T. Simon DK, et al. J Neurol Sci. 2017 Apr 15;375:355-359. doi: 10.1016/j.jns.2017.02.032. Epub 2017 Feb 17. J Neurol Sci. 2017. PMID: 28320167 Free PMC article.
Caffeine is neuroprotective in animal models of Parkinson's disease (PD) and caffeine intake is inversely associated with the risk of PD. ...However, there was a 4-way interaction between GRIN2A genotype, caffeine, creatine and the …
Caffeine is neuroprotective in animal models of Parkinson's disease (PD) and caffeine intake is in …
Glutathione-Mediated Neuroprotective Effect of Purine Derivatives.
Matsumura N, Aoyama K. Matsumura N, et al. Int J Mol Sci. 2023 Aug 22;24(17):13067. doi: 10.3390/ijms241713067. Int J Mol Sci. 2023. PMID: 37685879 Free PMC article. Review.
Epidemiological studies have also shown the inverse association of appropriate caffeine intake or serum urate levels with neurodegenerative diseases such as Alzheimer disease (AD) and Parkinson's disease (PD). ...This review summar …
Epidemiological studies have also shown the inverse association of appropriate caffeine intake or serum urate levels with neurodeg …
Effects of caffeine in Parkinson's disease: from neuroprotection to the management of motor and non-motor symptoms.
Prediger RD. Prediger RD. J Alzheimers Dis. 2010;20 Suppl 1:S205-20. doi: 10.3233/JAD-2010-091459. J Alzheimers Dis. 2010. PMID: 20182024 Review.
Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting approximately 1% of the population older than 60 years. ...Altogether, the studies reviewed provide strong evidence that caffeine may represent a promising t …
Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting approximately 1% of the …
Neurodegenerative Diseases: Can Caffeine Be a Powerful Ally to Weaken Neuroinflammation?
Ruggiero M, Calvello R, Porro C, Messina G, Cianciulli A, Panaro MA. Ruggiero M, et al. Int J Mol Sci. 2022 Oct 26;23(21):12958. doi: 10.3390/ijms232112958. Int J Mol Sci. 2022. PMID: 36361750 Free PMC article. Review.
The most known chronic NDs are represented by Alzheimer's disease (AD), Parkinson's disease (PD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS) and Huntington's disease (HD). According to epidemiological studies, regular co …
The most known chronic NDs are represented by Alzheimer's disease (AD), Parkinson's disease (PD), multiple scler …
Caffeine; the Forgotten Potential for Parkinson's Disease.
Negida A, Elfil M, Attia, Farahat E, Gabr M, Essam A, Attia D, Ahmed H. Negida A, et al. CNS Neurol Disord Drug Targets. 2017;16(6):652-657. doi: 10.2174/1871527315666161107091149. CNS Neurol Disord Drug Targets. 2017. PMID: 27823571 Review.
BACKGROUND: Parkinson's disease (PD) is the second most common neurological disorder characterized by loss of dopaminergic fibers in the basal ganglia and presence of Lewy bodies. ...In this review, we discussed the potential of caffeine as a possible …
BACKGROUND: Parkinson's disease (PD) is the second most common neurological disorder characterized by loss of dopaminer …
Neuroprotection by caffeine in the MPTP model of parkinson's disease and its dependence on adenosine A2A receptors.
Xu K, Di Luca DG, Orrú M, Xu Y, Chen JF, Schwarzschild MA. Xu K, et al. Neuroscience. 2016 May 13;322:129-37. doi: 10.1016/j.neuroscience.2016.02.035. Epub 2016 Feb 22. Neuroscience. 2016. PMID: 26905951 Free PMC article.
Considerable epidemiological and laboratory data have suggested that caffeine, a nonselective adenosine receptor antagonist, may protect against the underlying neurodegeneration of parkinson's disease (PD). Although both caffeine and more specif …
Considerable epidemiological and laboratory data have suggested that caffeine, a nonselective adenosine receptor antagonist, may prot …
Protective Effects of the Caffeine Against Neurodegenerative Diseases.
Tellone E, Galtieri A, Russo A, Ficarra S. Tellone E, et al. Curr Med Chem. 2019;26(27):5137-5151. doi: 10.2174/0929867324666171009104040. Curr Med Chem. 2019. PMID: 28990513 Review.
BACKGROUND: Recent studies and increased interest of the scientific community helped to clarify the neurological health property of caffeine, one of the pharmacologically active substances most consumed in the world. METHODS: This article is a review search to provide an o …
BACKGROUND: Recent studies and increased interest of the scientific community helped to clarify the neurological health property of caffe …
Cautionary optimism: caffeine and Parkinson's disease risk.
Sokol LL, Young MJ, Espay AJ, Postuma RB. Sokol LL, et al. J Clin Mov Disord. 2016 Jun 6;3:7. doi: 10.1186/s40734-016-0037-8. eCollection 2016. J Clin Mov Disord. 2016. PMID: 27275394 Free PMC article.
Most Parkinson's disease (PD) patients present without known family history and without a diagnosed prodromal phase, underscoring the difficulty of employing primary (neuroprevention) and secondary (neuroprotection) preventions. ...We briefly analyze t …
Most Parkinson's disease (PD) patients present without known family history and without a diagnosed prodromal phase, un …
Neuroprotection by caffeine and more specific A2A receptor antagonists in animal models of Parkinson's disease.
Schwarzschild MA, Xu K, Oztas E, Petzer JP, Castagnoli K, Castagnoli N Jr, Chen JF. Schwarzschild MA, et al. Neurology. 2003 Dec 9;61(11 Suppl 6):S55-61. doi: 10.1212/01.wnl.0000095214.53646.72. Neurology. 2003. PMID: 14663012 Review.
A remarkable convergence of epidemiologic and laboratory data has raised the possibility that caffeine reduces the risk of developing Parkinson's disease (PD) by preventing the degeneration of nigrostriatal dopaminergic neurons. ...Other studies demons …
A remarkable convergence of epidemiologic and laboratory data has raised the possibility that caffeine reduces the risk of developing …
210 results