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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1980 1
1985 2
1986 1
1987 4
1988 3
1989 4
1990 7
1991 3
1992 6
1993 9
1994 14
1995 16
1996 19
1997 18
1998 14
1999 22
2000 17
2001 11
2002 14
2003 19
2004 27
2005 20
2006 15
2007 17
2008 11
2009 19
2010 11
2011 15
2012 17
2013 20
2014 24
2015 23
2016 13
2017 23
2018 29
2019 29
2020 32
2021 16
2022 0
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519 results
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Page 1
Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.
Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD. Stockwell BR, et al. Cell. 2017 Oct 5;171(2):273-285. doi: 10.1016/j.cell.2017.09.021. Cell. 2017. PMID: 28985560 Free PMC article. Review.
The sensitivity to ferroptosis is tightly linked to numerous biological processes, including amino acid, iron, and polyunsaturated fatty acid metabolism, and the biosynthesis of glutathione, phospholipids, NADPH, and coenzyme Q(10). Ferroptosis has been implicated in the p …
The sensitivity to ferroptosis is tightly linked to numerous biological processes, including amino acid, iron, and polyunsaturated fatty aci …
Oxidative Stress in Cancer.
Hayes JD, Dinkova-Kostova AT, Tew KD. Hayes JD, et al. Cancer Cell. 2020 Aug 10;38(2):167-197. doi: 10.1016/j.ccell.2020.06.001. Epub 2020 Jul 9. Cancer Cell. 2020. PMID: 32649885 Free PMC article. Review.
Contingent upon concentration, reactive oxygen species (ROS) influence cancer evolution in apparently contradictory ways, either initiating/stimulating tumorigenesis and supporting transformation/proliferation of cancer cells or causing cell death. To accommodate hi …
Contingent upon concentration, reactive oxygen species (ROS) influence cancer evolution in apparently contradictory ways, either init …
Glutathione metabolism in cancer progression and treatment resistance.
Bansal A, Simon MC. Bansal A, et al. J Cell Biol. 2018 Jul 2;217(7):2291-2298. doi: 10.1083/jcb.201804161. Epub 2018 Jun 18. J Cell Biol. 2018. PMID: 29915025 Free PMC article. Review.
GSH preserves sufficient levels of cysteine and detoxifies xenobiotics while also conferring therapeutic resistance to cancer cells. ...It is crucial to the removal and detoxification of carcinogens, and alterations in this pathway can have a profound effect on cell …
GSH preserves sufficient levels of cysteine and detoxifies xenobiotics while also conferring therapeutic resistance to cancer
A Review of Dietary (Phyto)Nutrients for Glutathione Support.
Minich DM, Brown BI. Minich DM, et al. Nutrients. 2019 Sep 3;11(9):2073. doi: 10.3390/nu11092073. Nutrients. 2019. PMID: 31484368 Free PMC article. Review.
Importantly, genetic variation is a modifier of glutathione status and influences response to nutritional factors that impact glutathione levels. This narrative review explores clinical evidence for nutritional strategies that could be used to improve …
Importantly, genetic variation is a modifier of glutathione status and influences response to nutritional factors that impact glut
Role of glutathione in cancer progression and chemoresistance.
Traverso N, Ricciarelli R, Nitti M, Marengo B, Furfaro AL, Pronzato MA, Marinari UM, Domenicotti C. Traverso N, et al. Oxid Med Cell Longev. 2013;2013:972913. doi: 10.1155/2013/972913. Epub 2013 May 20. Oxid Med Cell Longev. 2013. PMID: 23766865 Free PMC article. Review.
Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell differentiation, proliferation, and apoptosis, and disturbances in GSH homeostasis are involved in the etiology and progression of many human diseases including cancer
Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell differentiation, proliferation, and ap
Isothiocyanate from Broccoli, Sulforaphane, and Its Properties.
Vanduchova A, Anzenbacher P, Anzenbacherova E. Vanduchova A, et al. J Med Food. 2019 Feb;22(2):121-126. doi: 10.1089/jmf.2018.0024. Epub 2018 Oct 27. J Med Food. 2019. PMID: 30372361 Review.
Sulforaphane is metabolized through mercapturic acid pathway, being conjugated with glutathione and undergoes further biotransformation, yielding metabolites. ...Our review offers a short summary of interesting properties of sulforaphane. ...
Sulforaphane is metabolized through mercapturic acid pathway, being conjugated with glutathione and undergoes further biotransformati …
Free radicals, metals and antioxidants in oxidative stress-induced cancer.
Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M. Valko M, et al. Chem Biol Interact. 2006 Mar 10;160(1):1-40. doi: 10.1016/j.cbi.2005.12.009. Epub 2006 Jan 23. Chem Biol Interact. 2006. PMID: 16430879 Review.
DNA mutation is a critical step in carcinogenesis and elevated levels of oxidative DNA lesions (8-OH-G) have been noted in various tumours, strongly implicating such damage in the etiology of cancer. It appears that the DNA damage is predominantly linked with the in …
DNA mutation is a critical step in carcinogenesis and elevated levels of oxidative DNA lesions (8-OH-G) have been noted in various tu …
Ferroptosis and necroinflammation, a yet poorly explored link.
Proneth B, Conrad M. Proneth B, et al. Cell Death Differ. 2019 Jan;26(1):14-24. doi: 10.1038/s41418-018-0173-9. Epub 2018 Aug 6. Cell Death Differ. 2019. PMID: 30082768 Free PMC article. Review.
Ferroptosis is a non-apoptotic form of cell death characterized by overwhelming iron-dependent lipid peroxidation, which contributes to a number of pathologies, most notably tissue ischemia/reperfusion injury, neurodegeneration and cancer. Cysteine availability, glutath
Ferroptosis is a non-apoptotic form of cell death characterized by overwhelming iron-dependent lipid peroxidation, which contributes to a nu …
Nothing Boring About Boron.
Pizzorno L. Pizzorno L. Integr Med (Encinitas). 2015 Aug;14(4):35-48. Integr Med (Encinitas). 2015. PMID: 26770156 Free PMC article. Review.
As the current article shows, boron has been proven to be an important trace mineral because it (1) is essential for the growth and maintenance of bone; (2) greatly improves wound healing; (3) beneficially impacts the body's use of estrogen, testosterone, and vitamin D; (4 …
As the current article shows, boron has been proven to be an important trace mineral because it (1) is essential for the growth and maintena …
Targeting Free Radicals in Oxidative Stress-Related Human Diseases.
Poprac P, Jomova K, Simunkova M, Kollar V, Rhodes CJ, Valko M. Poprac P, et al. Trends Pharmacol Sci. 2017 Jul;38(7):592-607. doi: 10.1016/j.tips.2017.04.005. Epub 2017 May 24. Trends Pharmacol Sci. 2017. PMID: 28551354 Review.
Cancer and Alzheimer's disease (AD) are characterized by (i) opposing biological mechanisms, (ii) an inverse correlation between their incidences, and (iii) oxidative stress being a common denominator of both diseases. Increased formation of reactive oxygen species
Cancer and Alzheimer's disease (AD) are characterized by (i) opposing biological mechanisms, (ii) an inverse correlation betwe
519 results