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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1934 1
1945 2
1946 4
1947 5
1948 7
1949 5
1950 4
1951 14
1952 9
1953 11
1954 5
1955 6
1956 7
1957 12
1958 9
1959 8
1960 17
1961 11
1962 13
1963 10
1964 14
1965 19
1966 12
1967 15
1968 22
1969 17
1970 28
1971 30
1972 30
1973 19
1974 27
1975 183
1976 208
1977 191
1978 222
1979 239
1980 234
1981 267
1982 280
1983 337
1984 352
1985 346
1986 336
1987 350
1988 468
1989 586
1990 567
1991 558
1992 608
1993 732
1994 769
1995 796
1996 833
1997 966
1998 942
1999 1080
2000 1085
2001 1181
2002 1196
2003 1280
2004 1400
2005 1507
2006 1524
2007 1735
2008 1817
2009 2000
2010 2146
2011 2336
2012 2417
2013 2677
2014 2953
2015 3011
2016 3090
2017 3303
2018 3540
2019 3783
2020 4350
2021 4851
2022 4775
2023 4827
2024 5100
2025 674

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73,549 results

Results by year

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Page 1
The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection.
Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR. Patel SG, et al. Lancet Gastroenterol Hepatol. 2022 Mar;7(3):262-274. doi: 10.1016/S2468-1253(21)00426-X. Epub 2022 Jan 26. Lancet Gastroenterol Hepatol. 2022. PMID: 35090605 Review.
The incidence of early-onset colorectal cnacer-ie, colorectal cancer diagnosed in patients under the age of 50 years- has been increasing around the world. This Series paper provides a comprehensive review on the topic of early-onset colorectal canc
The incidence of early-onset colorectal cnacer-ie, colorectal cancer diagnosed in patients under the age of 50 years- h …
A comprehensive framework for early-onset colorectal cancer research.
Eng C, Jácome AA, Agarwal R, Hayat MH, Byndloss MX, Holowatyj AN, Bailey C, Lieu CH. Eng C, et al. Lancet Oncol. 2022 Mar;23(3):e116-e128. doi: 10.1016/S1470-2045(21)00588-X. Epub 2022 Jan 31. Lancet Oncol. 2022. PMID: 35090673 Review.
In this Series paper, we discuss the potential underlying causes of early-onset colorectal cancer, the role of energy balance, biological and genomic mechanisms (including microbiome aspects), and the treatment of early-onset colorectal cancer. We have …
In this Series paper, we discuss the potential underlying causes of early-onset colorectal cancer, the role of energy balance, …
Early-Onset Cancer in the Gastrointestinal Tract Is on the Rise-Evidence and Implications.
Ben-Aharon I, van Laarhoven HWM, Fontana E, Obermannova R, Nilsson M, Lordick F. Ben-Aharon I, et al. Cancer Discov. 2023 Mar 1;13(3):538-551. doi: 10.1158/2159-8290.CD-22-1038. Cancer Discov. 2023. PMID: 36757194 Review.
Epidemiologic data indicate a significant increase in the incidence of colorectal cancer in younger populations in the past three decades. Moreover, recent evidence also demonstrates a similar trend in gastric, pancreatic, and biliary tract cancers. ...This review e …
Epidemiologic data indicate a significant increase in the incidence of colorectal cancer in younger populations in the past three dec …
New-Onset Age of Nonalcoholic Fatty Liver Disease and Cancer Risk.
Liu C, Liu T, Zhang Q, Jia P, Song M, Zhang Q, Ruan G, Ge Y, Lin S, Wang Z, Xie H, Shi J, Han R, Chen Y, Zheng X, Shen L, Deng L, Wu S, Shi H. Liu C, et al. JAMA Netw Open. 2023 Sep 5;6(9):e2335511. doi: 10.1001/jamanetworkopen.2023.35511. JAMA Netw Open. 2023. PMID: 37747732 Free PMC article.
IMPORTANCE: The onset age of nonalcoholic fatty liver disease (NAFLD) is decreasing, and whether earlier ages of NAFLD onset are associated with increased cancer risk is currently unclear. ...PAFs also showed that in patients aged less than 45 years at …
IMPORTANCE: The onset age of nonalcoholic fatty liver disease (NAFLD) is decreasing, and whether earlier ages of NAFLD onse
Addressing the rise of early-onset colorectal cancer.
The Lancet Gastroenterology Hepatology. The Lancet Gastroenterology Hepatology. Lancet Gastroenterol Hepatol. 2022 Mar;7(3):197. doi: 10.1016/S2468-1253(22)00003-6. Epub 2022 Jan 31. Lancet Gastroenterol Hepatol. 2022. PMID: 35093209 No abstract available.
Early-Onset colorectal Cancer: From the laboratory to the clinic.
Gandini A, Taieb J, Blons H, Netter J, Laurent-Puig P, Gallois C. Gandini A, et al. Cancer Treat Rev. 2024 Nov;130:102821. doi: 10.1016/j.ctrv.2024.102821. Epub 2024 Aug 30. Cancer Treat Rev. 2024. PMID: 39236404 Free article. Review.
Colorectal cancer that occurs before age of 50 is defined as Early-Onset Colorectal Cancer (EOCRC). ...However, lot of questions remain open, including screening age and prognosis. Indeed, young patients tend to be treated more aggressively, eve …
Colorectal cancer that occurs before age of 50 is defined as Early-Onset Colorectal Cancer (EOCRC). ...However, …
Early onset colorectal cancer: Cancer promotion in young tissue.
Giardina C, Kuo A, Nito K, Kurkcu S. Giardina C, et al. Biochem Pharmacol. 2024 Aug;226:116393. doi: 10.1016/j.bcp.2024.116393. Epub 2024 Jun 26. Biochem Pharmacol. 2024. PMID: 38942088 Review.
The incidence of colorectal cancer (CRC) in patients under 50 has been increasing over the past several decades. The factors underlying the increase in early onset colorectal cancer (EOCRC) are not entirely clear, although several genetic and clinical differe …
The incidence of colorectal cancer (CRC) in patients under 50 has been increasing over the past several decades. The factors underlyi …
Non-hereditary early onset gastric cancer: An unmet medical need.
Petrillo A, Federico P, Marte G, Liguori C, Seeber A, Ottaviano M, Tufo A, Daniele B. Petrillo A, et al. Curr Opin Pharmacol. 2023 Feb;68:102344. doi: 10.1016/j.coph.2022.102344. Epub 2023 Jan 4. Curr Opin Pharmacol. 2023. PMID: 36608410 Review.
Gastric cancer (GC) is a lethal disease and the diagnosis in the young population is a major challenge from both individual and social point of views. Early-onset GC accounts for 5% of GC; among them, 3% are part of a hereditary syndrome and the majority are sporadi …
Gastric cancer (GC) is a lethal disease and the diagnosis in the young population is a major challenge from both individual and socia …
73,549 results
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