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Synthesis and in vitro antiproliferative evaluation of PEGylated triterpene acids.
Medina-O'Donnell M, Rivas F, Reyes-Zurita FJ, Martinez A, Galisteo-González F, Lupiañez JA, Parra A. Medina-O'Donnell M, et al. Fitoterapia. 2017 Jul;120:25-40. doi: 10.1016/j.fitote.2017.05.006. Epub 2017 May 25. Fitoterapia. 2017. PMID: 28552598
Another set of PEGylated derivatives has been semi-synthesised by connecting the same four ethylene glycols to the hydroxyl groups of the A ring of these triterpenic acids, through a carbonate linker, by reaction with trichloromethyl chloroformate. The aqueous solub …
Another set of PEGylated derivatives has been semi-synthesised by connecting the same four ethylene glycols to the hydroxyl groups of the A …
Synthesis of targeted drug delivery system for fluorouracil using sulfadiazine as the carrier.
Hu XG, Wang SM, Zhang QX, Cao MM, Lu Y. Hu XG, et al. Di Yi Jun Yi Da Xue Xue Bao. 2002 Nov;22(11):1042-4. Di Yi Jun Yi Da Xue Xue Bao. 2002. PMID: 12433646
METHODS: SF-poly (ethylene glycol) (PEG) conjugate was initially synthesized. 5Fu was subjected to reaction with trichloromethyl chloroformate to prepare chloroformyl 5Fu, which was linked to a spacer hydroxyl group of PEG that served as a macromolecular linking arm …
METHODS: SF-poly (ethylene glycol) (PEG) conjugate was initially synthesized. 5Fu was subjected to reaction with trichloromethyl c …