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Year Number of Results
2000 1
2004 1
2012 1
2016 1
2017 9
2018 54
2019 1445
2020 11374
2021 44
2022 3
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11,374 results
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Page 1
Emerging Mechanisms and Disease Relevance of Ferroptosis.
Stockwell BR, Jiang X, Gu W. Stockwell BR, et al. Trends Cell Biol. 2020 Jun;30(6):478-490. doi: 10.1016/j.tcb.2020.02.009. Epub 2020 Mar 21. Trends Cell Biol. 2020. PMID: 32413317 Free PMC article. Review.
Cell death is an essential feature of development in multicellular organisms, a critical driver of degenerative diseases, and can be harnessed for treating some cancers. Understanding the mechanisms governing cell death is critical for addressing its role in disease. ...
Cell death is an essential feature of development in multicellular organisms, a critical driver of degenerative diseases, and can be harness …
Role of RNA modifications in cancer.
Barbieri I, Kouzarides T. Barbieri I, et al. Nat Rev Cancer. 2020 Jun;20(6):303-322. doi: 10.1038/s41568-020-0253-2. Epub 2020 Apr 16. Nat Rev Cancer. 2020. PMID: 32300195 Review.
Many of the enzymes responsible for regulating protein and DNA modifications are targets of current cancer therapies. RNA epitranscriptomics, the study of RNA modifications, is the new frontier of this arena. ...Increasing evidence suggests that RNA modification pathways a …
Many of the enzymes responsible for regulating protein and DNA modifications are targets of current cancer therapies. RNA epitranscri …
Cancer Incidence and Trends.
Hulvat MC. Hulvat MC. Surg Clin North Am. 2020 Jun;100(3):469-481. doi: 10.1016/j.suc.2020.01.002. Epub 2020 Mar 27. Surg Clin North Am. 2020. PMID: 32402294 Review.
The incidence of many types of cancer continues to increase, and despite many successes in the realms of screening, prevention, and treatment, cancer remains the second leading cause of death in North America. ...These cancer survivors face unique challenges …
The incidence of many types of cancer continues to increase, and despite many successes in the realms of screening, prevention, and t …
Review of precision cancer medicine: Evolution of the treatment paradigm.
Tsimberidou AM, Fountzilas E, Nikanjam M, Kurzrock R. Tsimberidou AM, et al. Cancer Treat Rev. 2020 Jun;86:102019. doi: 10.1016/j.ctrv.2020.102019. Epub 2020 Mar 31. Cancer Treat Rev. 2020. PMID: 32251926 Free PMC article. Review.
The majority of these trials demonstrated that matched therapy is associated with superior outcomes compared to non-matched therapy across tumor types and in specific cancers. To improve the implementation of precision medicine, this approach should be used early in the co …
The majority of these trials demonstrated that matched therapy is associated with superior outcomes compared to non-matched therapy across t …
Anal Cancer.
Young AN, Jacob E, Willauer P, Smucker L, Monzon R, Oceguera L. Young AN, et al. Surg Clin North Am. 2020 Jun;100(3):629-634. doi: 10.1016/j.suc.2020.02.007. Epub 2020 Mar 27. Surg Clin North Am. 2020. PMID: 32402305 Review.
Anal cancer is a rare cancer, comprising less than 5% of gastrointestinal tract malignancies. Diagnosis of anal canal cancer can be difficult given that presenting symptoms are similar to those of benign anorectal diseases. ...
Anal cancer is a rare cancer, comprising less than 5% of gastrointestinal tract malignancies. Diagnosis of anal canal cance
Papillary Thyroid Cancer-Aggressive Variants and Impact on Management: A Narrative Review.
Coca-Pelaz A, Shah JP, Hernandez-Prera JC, Ghossein RA, Rodrigo JP, Hartl DM, Olsen KD, Shaha AR, Zafereo M, Suarez C, Nixon IJ, Randolph GW, Mäkitie AA, Kowalski LP, Vander Poorten V, Sanabria A, Guntinas-Lichius O, Simo R, Zbären P, Angelos P, Khafif A, Rinaldo A, Ferlito A. Coca-Pelaz A, et al. Adv Ther. 2020 Jul;37(7):3112-3128. doi: 10.1007/s12325-020-01391-1. Epub 2020 Jun 1. Adv Ther. 2020. PMID: 32488657 Free PMC article. Review.
INTRODUCTION: Aggressive variants of papillary thyroid cancer (PTC) have been described with increasing frequency. These variants include diffuse sclerosing variant, tall cell variant, columnar cell variant, solid variant, and hobnail variant. ...
INTRODUCTION: Aggressive variants of papillary thyroid cancer (PTC) have been described with increasing frequency. These variants inc …
Memory CD8+ T cell responses to cancer.
Han J, Khatwani N, Searles TG, Turk MJ, Angeles CV. Han J, et al. Semin Immunol. 2020 Jun;49:101435. doi: 10.1016/j.smim.2020.101435. Epub 2020 Nov 30. Semin Immunol. 2020. PMID: 33272898 Free PMC article. Review.
Studies over the past two decades have identified four subsets of memory CD8(+) T cells - central, effector, stem-like, and tissue resident memory - that either circulate through blood, lymphoid and peripheral organs, or reside in tissues where cancers develop. In this art …
Studies over the past two decades have identified four subsets of memory CD8(+) T cells - central, effector, stem-like, and tissue resident …
Cancer Genetics.
Van Cott C. Van Cott C. Surg Clin North Am. 2020 Jun;100(3):483-498. doi: 10.1016/j.suc.2020.02.012. Epub 2020 Apr 16. Surg Clin North Am. 2020. PMID: 32402295 Review.
For most individuals, cancer development is multifactorial; however, up to 10% of all cancers are related to an inherited genetic mutation. As health care shifts to having a greater emphasis on prevention, care providers, including general surgeons, will need to pla …
For most individuals, cancer development is multifactorial; however, up to 10% of all cancers are related to an inherited gene …
DC-CIK as a widely applicable cancer immunotherapy.
Wang S, Wang X, Zhou X, Lyerly HK, Morse MA, Ren J. Wang S, et al. Expert Opin Biol Ther. 2020 Jun;20(6):601-607. doi: 10.1080/14712598.2020.1728250. Epub 2020 Feb 13. Expert Opin Biol Ther. 2020. PMID: 32033522 Review.
A widely applicable, non-MHC dependent, cellular therapy, consisting of in vitro generated dendritic cells (DC) combined with cytokine-induced killer cells (CIK), is highly efficient to produce from individual patients and has demonstrated safety and efficacy alone or with chemot …
A widely applicable, non-MHC dependent, cellular therapy, consisting of in vitro generated dendritic cells (DC) combined with cytokine-induc …
Tim-3 finds its place in the cancer immunotherapy landscape.
Acharya N, Sabatos-Peyton C, Anderson AC. Acharya N, et al. J Immunother Cancer. 2020 Jun;8(1):e000911. doi: 10.1136/jitc-2020-000911. J Immunother Cancer. 2020. PMID: 32601081 Free PMC article. Review.
The blockade of immune checkpoint receptors has made great strides in the treatment of major cancers, including melanoma, Hodgkin's lymphoma, renal, and lung cancer. However, the success rate of immune checkpoint blockade is still low and some cancers, …
The blockade of immune checkpoint receptors has made great strides in the treatment of major cancers, including melanoma, Hodgkin' …
11,374 results
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