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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1890 1
1914 2
1918 1
1919 1
1925 1
1928 1
1929 1
1930 1
1932 1
1933 3
1934 5
1935 8
1936 9
1937 4
1938 3
1939 1
1940 1
1941 3
1942 1
1943 1
1944 1
1945 7
1946 29
1947 24
1948 14
1949 24
1950 16
1951 55
1952 64
1953 81
1954 80
1955 99
1956 135
1957 126
1958 153
1959 128
1960 149
1961 129
1962 90
1963 128
1964 199
1965 224
1966 288
1967 346
1968 331
1969 400
1970 505
1971 571
1972 607
1973 751
1974 810
1975 913
1976 1060
1977 1204
1978 1293
1979 1359
1980 1497
1981 1560
1982 1404
1983 1527
1984 1663
1985 1973
1986 2142
1987 2389
1988 3200
1989 3492
1990 4270
1991 4293
1992 4720
1993 5223
1994 5571
1995 6191
1996 6959
1997 7499
1998 8358
1999 9054
2000 10969
2001 12190
2002 13017
2003 14628
2004 16234
2005 17950
2006 19671
2007 21900
2008 23671
2009 25742
2010 28871
2011 32662
2012 35804
2013 38950
2014 43028
2015 44687
2016 45789
2017 45527
2018 47317
2019 50874
2020 51154
2021 49515
2022 46271
2023 40980
2024 53092
2025 3979

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838,305 results

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Page 1
Targeting cancer metabolism in the era of precision oncology.
Stine ZE, Schug ZT, Salvino JM, Dang CV. Stine ZE, et al. Nat Rev Drug Discov. 2022 Feb;21(2):141-162. doi: 10.1038/s41573-021-00339-6. Epub 2021 Dec 3. Nat Rev Drug Discov. 2022. PMID: 34862480 Free PMC article. Review.
One hundred years have passed since Warburg discovered alterations in cancer metabolism, more than 70 years since Sidney Farber introduced anti-folates that transformed the treatment of childhood leukaemia, and 20 years since metabolism was linked to oncogene …
One hundred years have passed since Warburg discovered alterations in cancer metabolism, more than 70 years since Sidney Farbe …
Cancer Metabolism: Phenotype, Signaling and Therapeutic Targets.
Park JH, Pyun WY, Park HW. Park JH, et al. Cells. 2020 Oct 16;9(10):2308. doi: 10.3390/cells9102308. Cells. 2020. PMID: 33081387 Free PMC article. Review.
Aberrant metabolism is a major hallmark of cancer. Abnormal cancer metabolism, such as aerobic glycolysis and increased anabolic pathways, has important roles in tumorigenesis, metastasis, drug resistance, and cancer stem cells. ...We also provi …
Aberrant metabolism is a major hallmark of cancer. Abnormal cancer metabolism, such as aerobic glycolysis and in …
Cancer Metabolism as a Therapeutic Target and Review of Interventions.
Halma MTJ, Tuszynski JA, Marik PE. Halma MTJ, et al. Nutrients. 2023 Oct 1;15(19):4245. doi: 10.3390/nu15194245. Nutrients. 2023. PMID: 37836529 Free PMC article. Review.
Cancer is amenable to low-cost treatments, given that it has a significant metabolic component, which can be affected through diet and lifestyle change at minimal cost. The Warburg hypothesis states that cancer cells have an altered cell metabolism towards an
Cancer is amenable to low-cost treatments, given that it has a significant metabolic component, which can be affected through diet an
The role of ubiquitination and deubiquitination in cancer metabolism.
Sun T, Liu Z, Yang Q. Sun T, et al. Mol Cancer. 2020 Oct 1;19(1):146. doi: 10.1186/s12943-020-01262-x. Mol Cancer. 2020. PMID: 33004065 Free PMC article. Review.
Metabolic reprogramming, including enhanced biosynthesis of macromolecules, altered energy metabolism, and maintenance of redox homeostasis, is considered a hallmark of cancer, sustaining cancer cell growth. Multiple signaling pathways, transcription factors …
Metabolic reprogramming, including enhanced biosynthesis of macromolecules, altered energy metabolism, and maintenance of redox homeo …
Glucose Metabolism in Cancer.
Bose S, Le A. Bose S, et al. Adv Exp Med Biol. 2018;1063:3-12. doi: 10.1007/978-3-319-77736-8_1. Adv Exp Med Biol. 2018. PMID: 29946772 Review.
Otto Warburg observed a peculiar phenomenon in 1924, unknowingly laying the foundation for the field of cancer metabolism. While his contemporaries hypothesized that tumor cells derived the energy required for uncontrolled replication from proteolysis and lipolysis, …
Otto Warburg observed a peculiar phenomenon in 1924, unknowingly laying the foundation for the field of cancer metabolism. Whi …
PKM2, cancer metabolism, and the road ahead.
Dayton TL, Jacks T, Vander Heiden MG. Dayton TL, et al. EMBO Rep. 2016 Dec;17(12):1721-1730. doi: 10.15252/embr.201643300. Epub 2016 Nov 17. EMBO Rep. 2016. PMID: 27856534 Free PMC article. Review.
A major metabolic aberration associated with cancer is a change in glucose metabolism. Isoform selection of the glycolytic enzyme pyruvate kinase has been implicated in the metabolic phenotype of cancer cells, and specific pyruvate kinase isoforms have been s …
A major metabolic aberration associated with cancer is a change in glucose metabolism. Isoform selection of the glycolytic enz …
Cancer metabolism.
Pietrobon V. Pietrobon V. J Transl Med. 2021 Feb 25;19(1):87. doi: 10.1186/s12967-021-02753-1. J Transl Med. 2021. PMID: 33632223 Free PMC article. No abstract available.
CircRNAs in cancer metabolism: a review.
Yu T, Wang Y, Fan Y, Fang N, Wang T, Xu T, Shu Y. Yu T, et al. J Hematol Oncol. 2019 Sep 4;12(1):90. doi: 10.1186/s13045-019-0776-8. J Hematol Oncol. 2019. PMID: 31484561 Free PMC article. Review.
Altered energy metabolism is a hallmark of tumors aiming at supplying necessary nutrients for tumorigenesis and development. ...In addition, we also discuss the possibility of circRNAs exerting their functions via exosomes and cancer stem cells. Owing to their uniqu …
Altered energy metabolism is a hallmark of tumors aiming at supplying necessary nutrients for tumorigenesis and development. ...In ad …
Diet and Cancer Metabolism.
Locasale JW, Goncalves MD, Di Tano M, Burgos-Barragan G. Locasale JW, et al. Cold Spring Harb Perspect Med. 2024 Dec 2;14(12):a041549. doi: 10.1101/cshperspect.a041549. Cold Spring Harb Perspect Med. 2024. PMID: 38621831 Review.
Despite enormous public interest, there are limited defined diet and exercise regimens for cancer patients. Nevertheless, the molecular basis of cancer has converged over the past 15 years on an essential role for altered metabolism in cancer. However, …
Despite enormous public interest, there are limited defined diet and exercise regimens for cancer patients. Nevertheless, the molecul …
Glucose Metabolism in Cancer: The Warburg Effect and Beyond.
Bose S, Zhang C, Le A. Bose S, et al. Adv Exp Med Biol. 2021;1311:3-15. doi: 10.1007/978-3-030-65768-0_1. Adv Exp Med Biol. 2021. PMID: 34014531 Free PMC article.
Otto Warburg observed a peculiar phenomenon in 1924, unknowingly laying the foundation for the field of cancer metabolism. While his contemporaries hypothesized that tumor cells derived the energy required for uncontrolled replication from proteolysis and lipolysis, …
Otto Warburg observed a peculiar phenomenon in 1924, unknowingly laying the foundation for the field of cancer metabolism. Whi …
838,305 results
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