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Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis.
Filippini G, Minozzi S, Borrelli F, Cinquini M, Dwan K. Filippini G, et al. Cochrane Database Syst Rev. 2022 May 5;5(5):CD013444. doi: 10.1002/14651858.CD013444.pub2. Cochrane Database Syst Rev. 2022. PMID: 35510826 Free PMC article.
HRQoL: cannabinoids may have little to no effect on HRQoL (SMD -0.08, 95% CI -0.17 to 0.02; 8 studies, 1942 participants; I(2) = 0%; low-certainty evidence); SAEs: cannabinoids may result in little to no difference in the number of participants who have SAEs compared with place …
HRQoL: cannabinoids may have little to no effect on HRQoL (SMD -0.08, 95% CI -0.17 to 0.02; 8 studies, 1942 participants; I(2) = 0%; low-cer …
Combination CBD/THC in the management of chemotherapy-induced peripheral neuropathy: a randomized double blind controlled trial.
Weiss M, Giaddui M, Kjelstrom S, Gary J, Ward SJ, Burrell J, Diguilio K, Bidas G, Erebor E, Meske S, Saeed L, Windawi S, Aliano Ruiz K, Ghaneie A, Hibbs J, Marks J, Holtz D, Ali Z, Shevade A, Sabol J, Ciocca R, Zeger E, Gilman P, Larson S, Shimamoto S, Martinez D. Weiss M, et al. Front Oncol. 2025 Oct 23;15:1590168. doi: 10.3389/fonc.2025.1590168. eCollection 2025. Front Oncol. 2025. PMID: 41211445 Free PMC article.
INTRODUCTION: Chemotherapy-induced peripheral neuropathy (CIPN) can greatly impair function, leading to disability or truncated treatment in cancer patients. Previous animal studies show that cannabidiol (CBD) and delta-9- tetrahydrocannabinol (THC) ca …
INTRODUCTION: Chemotherapy-induced peripheral neuropathy (CIPN) can greatly impair function, leading to disability or t …
Efficient Synthesis for Altering Side Chain Length on Cannabinoid Molecules and Their Effects in Chemotherapy and Chemotherapeutic Induced Neuropathic Pain.
Raup-Konsavage WM, Sepulveda DE, Morris DP, Amin S, Vrana KE, Graziane NM, Desai D. Raup-Konsavage WM, et al. Biomolecules. 2022 Dec 13;12(12):1869. doi: 10.3390/biom12121869. Biomolecules. 2022. PMID: 36551296 Free PMC article.
(1) Background: Recently, a number of side chain length variants for tetrahydrocannabinol and cannabidiol have been identified in cannabis; however, the precursor to these molecules would be based upon cannabigerol (CBG). ...These compounds were then tested in an animal mo …
(1) Background: Recently, a number of side chain length variants for tetrahydrocannabinol and cannabidiol have been identified in can …