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1978 1
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1988 3
1989 2
1990 20
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Page 1
Cannabinoid receptors: where they are and what they do.
Mackie K. Mackie K. J Neuroendocrinol. 2008 May;20 Suppl 1:10-4. doi: 10.1111/j.1365-2826.2008.01671.x. J Neuroendocrinol. 2008. PMID: 18426493 Review.
The endocannabinoid system consists of the endogenous cannabinoids (endocannabinoids), cannabinoid receptors and the enzymes that synthesise and degrade endocannabinoids. Many of the effects of cannabinoids and endocannabinoids are mediated by two G protein-coupled …
The endocannabinoid system consists of the endogenous cannabinoids (endocannabinoids), cannabinoid receptors and the enzymes t …
Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System.
Zou S, Kumar U. Zou S, et al. Int J Mol Sci. 2018 Mar 13;19(3):833. doi: 10.3390/ijms19030833. Int J Mol Sci. 2018. PMID: 29533978 Free PMC article. Review.
The biological effects of cannabinoids, the major constituents of the ancient medicinal plant Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled receptor family, cannabinoid receptors 1 (CB1R) and 2. The CB1R is the prominent subtype in …
The biological effects of cannabinoids, the major constituents of the ancient medicinal plant Cannabis sativa (marijuana) are mediated by tw …
Microglial Cannabinoid CB(2) Receptors in Pain Modulation.
Xu K, Wu Y, Tian Z, Xu Y, Wu C, Wang Z. Xu K, et al. Int J Mol Sci. 2023 Jan 25;24(3):2348. doi: 10.3390/ijms24032348. Int J Mol Sci. 2023. PMID: 36768668 Free PMC article. Review.
Cannabinoids ponhave been reported to produce potent analgesic effects in different preclinical pain models, where they primarily function as agonists of G(i/o) protein-coupled cannabinoid CB(1) and CB(2) receptors. The CB(1) receptors are abundantly expresse …
Cannabinoids ponhave been reported to produce potent analgesic effects in different preclinical pain models, where they primarily function a …
Cannabinoid Receptors in Myocardial Injury: A Brother Born to Rival.
Tang X, Liu Z, Li X, Wang J, Li L. Tang X, et al. Int J Mol Sci. 2021 Jun 26;22(13):6886. doi: 10.3390/ijms22136886. Int J Mol Sci. 2021. PMID: 34206926 Free PMC article. Review.
Cannabinoid receptors typically include type 1 (CB1) and type 2 (CB2), and they have attracted extensive attention in the central nervous system (CNS) and immune system. ...Herein, we introduce the general differences of CB1 and CB2 cannabinoid receptors …
Cannabinoid receptors typically include type 1 (CB1) and type 2 (CB2), and they have attracted extensive attention in the cent …
Molecular Insights into Epigenetics and Cannabinoid Receptors.
Basavarajappa BS, Subbanna S. Basavarajappa BS, et al. Biomolecules. 2022 Oct 26;12(11):1560. doi: 10.3390/biom12111560. Biomolecules. 2022. PMID: 36358910 Free PMC article. Review.
Cannabinoid receptors are crucial candidates for exploring their functions through epigenetic approaches due to their significant roles in health and diseases. ...Despite the exponential growth of new evidence on the critical functions of cannabinoid recep …
Cannabinoid receptors are crucial candidates for exploring their functions through epigenetic approaches due to their signific …
Molecular Mechanism and Cannabinoid Pharmacology.
Schurman LD, Lu D, Kendall DA, Howlett AC, Lichtman AH. Schurman LD, et al. Handb Exp Pharmacol. 2020;258:323-353. doi: 10.1007/164_2019_298. Handb Exp Pharmacol. 2020. PMID: 32236882 Free PMC article.
These pharmacological tools were instrumental in the ultimate discovery of the endogenous cannabinoid system, which consists of CB(1) and CB(2) cannabinoid receptors and endogenously produced ligands (endocannabinoids), which bind and activate both cannabi …
These pharmacological tools were instrumental in the ultimate discovery of the endogenous cannabinoid system, which consists of CB(1) …
Novel cannabinoid receptors.
Brown AJ. Brown AJ. Br J Pharmacol. 2007 Nov;152(5):567-75. doi: 10.1038/sj.bjp.0707481. Epub 2007 Oct 1. Br J Pharmacol. 2007. PMID: 17906678 Free PMC article. Review.
However, there remain several examples where these classical cannabinoid receptors do not explain observed pharmacology. Studies using mice genetically deleted for the known receptors have confirmed the existence of additional targets, which have come to be k …
However, there remain several examples where these classical cannabinoid receptors do not explain observed pharmacology. Studi …
Cannabinoid receptors as therapeutic targets for autoimmune diseases: where do we stand?
Gonçalves ED, Dutra RC. Gonçalves ED, et al. Drug Discov Today. 2019 Sep;24(9):1845-1853. doi: 10.1016/j.drudis.2019.05.023. Epub 2019 May 31. Drug Discov Today. 2019. PMID: 31158514 Review.
Described during the late 1980s and 1990s, cannabinoid receptors (CB1R and CB2R) are G-protein-coupled receptors (GPCRs) activated by endogenous ligands and cannabinoid drug compounds, such as delta9-THC. ...
Described during the late 1980s and 1990s, cannabinoid receptors (CB1R and CB2R) are G-protein-coupled receptors (GPCRs …
Targeting Cannabinoid Receptors: Current Status and Prospects of Natural Products.
An D, Peigneur S, Hendrickx LA, Tytgat J. An D, et al. Int J Mol Sci. 2020 Jul 17;21(14):5064. doi: 10.3390/ijms21145064. Int J Mol Sci. 2020. PMID: 32709050 Free PMC article. Review.
Cannabinoid receptors (CB1 and CB2), as part of the endocannabinoid system, play a critical role in numerous human physiological and pathological conditions. ...However, only a few of these ligands are clinically used. Recently, more detailed structural information …
Cannabinoid receptors (CB1 and CB2), as part of the endocannabinoid system, play a critical role in numerous human physiologic …
Cannabinoid Receptors: An Update on Cell Signaling, Pathophysiological Roles and Therapeutic Opportunities in Neurological, Cardiovascular, and Inflammatory Diseases.
Haspula D, Clark MA. Haspula D, et al. Int J Mol Sci. 2020 Oct 17;21(20):7693. doi: 10.3390/ijms21207693. Int J Mol Sci. 2020. PMID: 33080916 Free PMC article. Review.
The identification of the human cannabinoid receptors and their roles in health and disease, has been one of the most significant biochemical and pharmacological advancements to have occurred in the past few decades. ...This review focusses mostly on the pathophysio …
The identification of the human cannabinoid receptors and their roles in health and disease, has been one of the most signific …
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