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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 4
1946 5
1947 5
1948 4
1949 1
1950 2
1951 3
1952 2
1953 3
1954 4
1958 2
1960 1
1961 1
1962 3
1963 2
1964 2
1965 2
1968 1
1969 5
1970 13
1971 58
1972 146
1973 234
1974 217
1975 171
1976 219
1977 214
1978 217
1979 166
1980 187
1981 185
1982 137
1983 145
1984 146
1985 132
1986 126
1987 147
1988 119
1989 115
1990 146
1991 177
1992 123
1993 146
1994 136
1995 215
1996 198
1997 244
1998 341
1999 335
2000 379
2001 442
2002 518
2003 578
2004 671
2005 914
2006 1003
2007 1168
2008 1348
2009 1230
2010 1374
2011 1420
2012 1502
2013 1403
2014 1526
2015 1564
2016 1755
2017 1736
2018 1809
2019 2060
2020 2463
2021 1781
Text availability
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Article type
Publication date

Search Results

30,162 results
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Page 1
The pharmacokinetics and the pharmacodynamics of cannabinoids.
Lucas CJ, Galettis P, Schneider J. Lucas CJ, et al. Br J Clin Pharmacol. 2018 Nov;84(11):2477-2482. doi: 10.1111/bcp.13710. Epub 2018 Aug 7. Br J Clin Pharmacol. 2018. PMID: 30001569 Free PMC article. Review.
There is increasing interest in the use of cannabinoids for disease and symptom management, but limited information available regarding their pharmacokinetics and pharmacodynamics to guide prescribers. Cannabis medicines contain a wide variety of chemical compounds, includ …
There is increasing interest in the use of cannabinoids for disease and symptom management, but limited information available regardi …
Pharmacokinetics and pharmacodynamics of cannabinoids.
Grotenhermen F. Grotenhermen F. Clin Pharmacokinet. 2003;42(4):327-60. doi: 10.2165/00003088-200342040-00003. Clin Pharmacokinet. 2003. PMID: 12648025 Review.
However, its acid metabolite THC-COOH, the non-psychotropic cannabidiol (CBD), several cannabinoid analogues and newly discovered modulators of the endogenous cannabinoid system are also promising candidates for clinical research and therapeutic uses. Cannabinoid
However, its acid metabolite THC-COOH, the non-psychotropic cannabidiol (CBD), several cannabinoid analogues and newly discovered mod …
Medical Use of Cannabinoids.
Fraguas-Sánchez AI, Torres-Suárez AI. Fraguas-Sánchez AI, et al. Drugs. 2018 Nov;78(16):1665-1703. doi: 10.1007/s40265-018-0996-1. Drugs. 2018. PMID: 30374797 Review.
Cannabinoids have shown promise as analgesics for the treatment of both inflammatory and neuropathic pain. ...Considering the importance of the endocannabinoid system and the therapeutic potential of cannabinoids in this vast number of medical conditions, several cl
Cannabinoids have shown promise as analgesics for the treatment of both inflammatory and neuropathic pain. ...Considering the importa
Cannabinoids: from pot to lab.
Papaseit E, Pérez-Mañá C, Pérez-Acevedo AP, Hladun O, Torres-Moreno MC, Muga R, Torrens M, Farré M. Papaseit E, et al. Int J Med Sci. 2018 Aug 6;15(12):1286-1295. doi: 10.7150/ijms.27087. eCollection 2018. Int J Med Sci. 2018. PMID: 30275754 Free PMC article. Review.
In recent years, the line between the natural (cannabis) and the synthetic (synthetic cannabinoids), the recreational (cannabis) and the medical (pharmaceutical cannabinoids and medical cannabis) has been crossed. ...We have also analyzed serious adverse reactions a …
In recent years, the line between the natural (cannabis) and the synthetic (synthetic cannabinoids), the recreational (cannabis) and …
Cannabinoids and the expanded endocannabinoid system in neurological disorders.
Cristino L, Bisogno T, Di Marzo V. Cristino L, et al. Nat Rev Neurol. 2020 Jan;16(1):9-29. doi: 10.1038/s41582-019-0284-z. Epub 2019 Dec 12. Nat Rev Neurol. 2020. PMID: 31831863 Review.
Anecdotal evidence that cannabis preparations have medical benefits together with the discovery of the psychotropic plant cannabinoid delta(9)-tetrahydrocannabinol (THC) initiated efforts to develop cannabinoid-based therapeutics. ...The approvals of nabiximols, a m …
Anecdotal evidence that cannabis preparations have medical benefits together with the discovery of the psychotropic plant cannabinoid
Pharmacogenetics of Cannabinoids.
Hryhorowicz S, Walczak M, Zakerska-Banaszak O, Słomski R, Skrzypczak-Zielińska M. Hryhorowicz S, et al. Eur J Drug Metab Pharmacokinet. 2018 Feb;43(1):1-12. doi: 10.1007/s13318-017-0416-z. Eur J Drug Metab Pharmacokinet. 2018. PMID: 28534260 Free PMC article. Review.
Knowledge based on proteins and molecules involved in the transport, action, and metabolism of cannabinoids in the human organism leads us to predict candidate genes which variations are responsible for the presence of the therapeutic and side effects of medical marijuana …
Knowledge based on proteins and molecules involved in the transport, action, and metabolism of cannabinoids in the human organism lea …
Pharmacology of cannabinoids in the treatment of epilepsy.
Gaston TE, Friedman D. Gaston TE, et al. Epilepsy Behav. 2017 May;70(Pt B):313-318. doi: 10.1016/j.yebeh.2016.11.016. Epub 2017 Jan 10. Epilepsy Behav. 2017. PMID: 28087250 Review.
We describe the absorption, distribution, metabolism, and excretion of each of the above mentioned compounds. Cannabinoids as a whole are very lipophilic, resulting in decreased bioavailability, which presents challenges in optimal drug delivery. ...This article is part of …
We describe the absorption, distribution, metabolism, and excretion of each of the above mentioned compounds. Cannabinoids as a whole …
Cannabinoids for Symptom Management and Cancer Therapy: The Evidence.
Davis MP. Davis MP. J Natl Compr Canc Netw. 2016 Jul;14(7):915-22. doi: 10.6004/jnccn.2016.0094. J Natl Compr Canc Netw. 2016. PMID: 27407130 Review.
Structurally, there are 3 groups of cannabinoids. Multiple studies, most of which are of moderate to low quality, demonstrate that tetrahydrocannabinol (THC) and oromucosal cannabinoid combinations of THC and cannabidiol (CBD) modestly reduce cancer pain. ...Preclin …
Structurally, there are 3 groups of cannabinoids. Multiple studies, most of which are of moderate to low quality, demonstrate that te …
Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications.
Castaneto MS, Gorelick DA, Desrosiers NA, Hartman RL, Pirard S, Huestis MA. Castaneto MS, et al. Drug Alcohol Depend. 2014 Nov 1;144:12-41. doi: 10.1016/j.drugalcdep.2014.08.005. Epub 2014 Aug 18. Drug Alcohol Depend. 2014. PMID: 25220897 Free PMC article. Review.
BACKGROUND: Synthetic cannabinoids (SC) are a heterogeneous group of compounds developed to probe the endogenous cannabinoid system or as potential therapeutics. ...In the early 2000s, SC became popular as "legal highs" under brand names such as Spice and K2, in par …
BACKGROUND: Synthetic cannabinoids (SC) are a heterogeneous group of compounds developed to probe the endogenous cannabinoid s …
The use of cannabinoids for sleep: A critical review on clinical trials.
Kuhathasan N, Dufort A, MacKillop J, Gottschalk R, Minuzzi L, Frey BN. Kuhathasan N, et al. Exp Clin Psychopharmacol. 2019 Aug;27(4):383-401. doi: 10.1037/pha0000285. Epub 2019 May 23. Exp Clin Psychopharmacol. 2019. PMID: 31120284
To further examine this association, we conducted a critical review of clinical studies examining the effects of cannabinoids on subjective and objective measures of sleep. PubMED, Web of Science, and Google Scholar were searched using terms and synonyms related to cann
To further examine this association, we conducted a critical review of clinical studies examining the effects of cannabinoids on subj …
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